MetaADEDB 2.0 @ LMMD
Chloramphenicol
(WIIZWVCIJKGZOK-RKDXNWHRSA-N)
Structure
SMILES
OC[C@H]([C@@H](c1ccc(cc1)[N+](=O)[O-])O)NC(=O)C(Cl)Cl
Type(s)
Approved; Vet_approved
ATC code(s)
D06AX02; D10AF03; G01AA05; J01BA01; S01AA01; S02AA01; S03AA08
Molecular Formula:
C11H12Cl2N2O5
Molecular Weight:
323.129
Log P:
1.8231
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
3
TPSA:
115.38
CAS Number(s):
56-75-7; 2787-09-9
Synonym(s)
1.
Chloramphenicol
2.
Cloranfenicol
3.
Kloramfenikol
4.
Levomycetin
5.
Amphenicol
6.
Amphenicols
7.
Chlornitromycin
8.
Chlorocid
9.
Chloromycetin
10.
Detreomycin
11.
Ophthochlor
12.
Syntomycin
External Link(s)
MeSHD002701
PubChem Compound5959
BindingDB23447
50028502
ChEBI17698
CHEMBLCHEMBL130
DrugBankDB00446
DrugCentral589
KEGGcpd:C00918
dr:D00104
Therapeutic Target DatabaseD0X6IU
ZINC113382
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Accidental overdoseFAERS: 5US FAERS
2BlindnessFAERS: 4US FAERS
3Eye irritationFAERS: 4SIDER
US FAERS
4HypersensitivityFAERS: 4SIDER
US FAERS
5Drug ineffectiveFAERS: 3US FAERS
6Drug label confusionFAERS: 3US FAERS
7Eye painFAERS: 3
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
8Incorrect route of drug administrationFAERS: 3US FAERS
9Intentional product misuseFAERS: 3US FAERS
10Achromotrichia acquiredFAERS: 2US FAERS
11CataractFAERS: 2US FAERS
12CyanosisFAERS: 24825630CTD
SIDER
US FAERS
13DeliriumFAERS: 2SIDER
US FAERS
14Drug dispensing errorFAERS: 2US FAERS
15HepatitisFAERS: 2OFFSIDES
US FAERS
16IridocyclitisFAERS: 2US FAERS
17MeningitisFAERS: 22041948
3289662
6416440		CTD
US FAERS
18Product label confusionFAERS: 2US FAERS
19Product use issueFAERS: 2US FAERS
20ShockFAERS: 2SIDER
US FAERS
21Unresponsive to stimuliFAERS: 2US FAERS
22Visual ImpairmentFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
23VitiligoFAERS: 2US FAERS
24pseudomembranous colitisFAERS: 2US FAERS
25Abdominal PainFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
26AngioedemaFAERS: 1
Canada Vigilance: 2		3994402CTD
SIDER
Canada Vigilance
US FAERS
27Corneal ScarFAERS: 1US FAERS
28Corneal abscessFAERS: 1US FAERS
29Corneal thinningFAERS: 1US FAERS
30EmpyemaFAERS: 1US FAERS
31Eye inflammationFAERS: 1OFFSIDES
US FAERS
32FatigueFAERS: 1
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
33General physical health deteriorationFAERS: 1US FAERS
34GlaucomaFAERS: 1OFFSIDES
US FAERS
35HypotensionFAERS: 12922508
10100024		CTD
US FAERS
36Local reactionFAERS: 1US FAERS
37MYELODYSPLASTIC SYNDROMEFAERS: 1US FAERS
38Medication residueFAERS: 1US FAERS
39Ocular discomfortFAERS: 1US FAERS
40Oropharyngeal painFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
41PancytopeniaFAERS: 1
Canada Vigilance: 3		6071896
7143157		CTD
SIDER
Canada Vigilance
US FAERS
42Postoperative wound complicationFAERS: 1US FAERS
43Potentiating drug interactionFAERS: 1OFFSIDES
US FAERS
44Product use in unapproved indicationFAERS: 1US FAERS
45Purulent dischargeFAERS: 1US FAERS
46SinusitisFAERS: 1US FAERS
47SymblepharonFAERS: 1US FAERS
48TachycardiaFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
49ThrombocytopeniaFAERS: 1
Canada Vigilance: 3		6071896CTD
SIDER
Canada Vigilance
US FAERS
50TonsillitisFAERS: 1US FAERS
51UveitisFAERS: 1US FAERS
52Wrong drug administeredFAERS: 1US FAERS
53AgranulocytosisCanada Vigilance: 21166296CTD
SIDER
Canada Vigilance
54AmnesiaOFFSIDES
55Anaphylactic shockSIDER
56Anemia

View details

5821752
7471903
11295484
16645427
 		CTD
57AngerOFFSIDES
58AnorexiaOFFSIDES
59AnxietyOFFSIDES
60Aphthous StomatitisOFFSIDES
61Application site reactionCanada Vigilance: 1Canada Vigilance
62Arthritis, Infectious16611451CTD
63Aseptic MeningitisOFFSIDES
64AtelectasisOFFSIDES
65AuraOFFSIDES
66Bacteroides Infections6139884CTD
67Blood and lymphatic system disordersSIDER
68Blood fibrinogenOFFSIDES
69Blood immunoglobulin A decreasedOFFSIDES
70Blood magnesium decreasedOFFSIDES
71Blood phosphorus decreasedOFFSIDES
72Blood potassium decreasedOFFSIDES
73Blood sodiumOFFSIDES
74Blurred visionOFFSIDES
75Bone Marrow Diseases4324369
4908993
6416440		CTD
76Bone marrow depressionSIDER
77Bradycardia2922508CTD
78Brain Abscess3289662
6139884		CTD
79BronchopneumoniaOFFSIDES
80BruxismOFFSIDES
81Burning sensationOFFSIDES
SIDER
82Cardioactive drug level increasedOFFSIDES
83Cataract operationOFFSIDES
84Cataract operation complicationOFFSIDES
85CatatoniaOFFSIDES
86Catheter related infectionOFFSIDES
87Central line infectionOFFSIDES
88Cerebral Hemorrhage6071896CTD
89Chemical and Drug Induced Liver Injury

View details

4800729
7143157
22331495
26881866
 		CTD
90ChillsCanada Vigilance: 1Canada Vigilance
91CholangiolitisOFFSIDES
92Cholestasis of pregnancyOFFSIDES
93ChromaturiaOFFSIDES
94Chronic granulomatous diseaseOFFSIDES
95ClumsinessOFFSIDES
96ConjunctivitisCanada Vigilance: 3Canada Vigilance
97Corneal UlcerOFFSIDES
98Corneal lesionCanada Vigilance: 1Canada Vigilance
99Croup infectiousOFFSIDES
100CryingOFFSIDES
101Deafness NeurosensoryOFFSIDES
102Deafness1085985CTD
103Depressed moodOFFSIDES
104DermatitisCanada Vigilance: 3Canada Vigilance
SIDER
105DizzinessCanada Vigilance: 2Canada Vigilance
106DrowsinessOFFSIDES
107Drug Overdose6416440CTD
108Drug exposure during pregnancyOFFSIDES
109Drug toxicityOFFSIDES
110DyspepsiaOFFSIDES
111Dysthymic DisorderOFFSIDES
112DysuriaOFFSIDES
113Emotional distressOFFSIDES
114EndophthalmitisSIDER
115EnterocolitisSIDER
116EntropionOFFSIDES
117Eosinophilia4800729CTD
118Epidermal necrosisOFFSIDES
119Epilepsy8487076CTD
120EpistaxisCanada Vigilance: 1Canada Vigilance
121Epstein-Barr virus associated lymphoproliferative disorderOFFSIDES
122ErythemaCanada Vigilance: 5Canada Vigilance
123Escherichia coli Infections1107297CTD
124Exanthema4800729CTD
125ExophthalmosOFFSIDES
126Eyelid DiseasesOFFSIDES
127Feeling abnormalSIDER
128Feelings of worthlessnessOFFSIDES
129Fever4800729CTD
130FlatulenceCanada Vigilance: 1Canada Vigilance
131FormicationOFFSIDES
132FrustrationOFFSIDES
133Gait Ataxia500438CTD
134Gastrointestinal Hemorrhage6071896CTD
135Gastrointestinal infectionOFFSIDES
136GlossitisCanada Vigilance: 1Canada Vigilance
SIDER
137Gram-Positive Bacterial Infections16000513
16584310		CTD
138Haemophilus Infections517570
3289662
7229771		CTD
139HeadacheCanada Vigilance: 2Canada Vigilance
SIDER
140Hearing Loss, Bilateral2041948
6715985		CTD
141Hemoglobinuria, Paroxysmal16212156CTD
142Hepatomegaly28108177CTD
143Hydrocephalus2041948CTD
144HypervigilanceOFFSIDES
145ImmunosuppressionOFFSIDES
146Inappropriate affectOFFSIDES
147Intentional self-injuryOFFSIDES
148Intraocular pressure testOFFSIDES
149KeratopathyOFFSIDES
150LagophthalmosOFFSIDES
151LethargyOFFSIDES
152LeukocytosisCanada Vigilance: 14800729CTD
Canada Vigilance
153LeukopeniaCanada Vigilance: 96071896
11295484		CTD
SIDER
Canada Vigilance
154Live BirthOFFSIDES
155Livedo ReticularisOFFSIDES
156Lower respiratory tract infection viralOFFSIDES
157Lung AbscessOFFSIDES
158Memory Disorders6817363CTD
159Meningitis, Bacterial16000513CTD
160Meningitis, Haemophilus

View details

306816
312922
343483
913899
1085985
 		CTD
161Meningitis, Pneumococcal1923686CTD
162Micronuclei, Chromosome-Defective23249641CTD
163Mitochondrial Diseases16207263CTD
164Mucoepidermoid CarcinomaOFFSIDES
165MutismOFFSIDES
166NauseaCanada Vigilance: 1Canada Vigilance
SIDER
167Necrosis26881866CTD
168Neonatal respiratory failureOFFSIDES
169Neoplasm Metastasis20338993CTD
170Nervous tensionOFFSIDES
171NeuralgiaOFFSIDES
172NeuritisSIDER
173Neurologic Manifestations6094437CTD
174NeutropeniaCanada Vigilance: 2Canada Vigilance
175Ocular ToxicityOFFSIDES
176OliguriaOFFSIDES
177Optic Atrophy420471
980520
4475322		CTD
178Optic Neuritis

View details

617068
839647
3380586
4175520
4742995
5087293
5706011
6047242
 		CTD
179Osteomyelitis839647
6071896		CTD
180OverdoseCanada Vigilance: 1Canada Vigilance
181PainCanada Vigilance: 28265690CTD
SIDER
Canada Vigilance
182PallorOFFSIDES
183Paresis2041948CTD
184ParophthalmiaOFFSIDES
185Peripheral Nervous System Diseases

View details

839647
3380586
4175520
4374461
 		CTD
186Peritonitis6071896CTD
187PetechiaeCanada Vigilance: 1Canada Vigilance
188Pharyngolaryngeal PainOFFSIDES
189Pneumonia2041948
4023934
6071896		CTD
190Post procedural complicationOFFSIDES
191PosturingOFFSIDES
192Pregnancy on oral contraceptiveOFFSIDES
193Proteus Infections1107297CTD
194PruritusCanada Vigilance: 6Canada Vigilance
SIDER
195Pseudomonas Infections1107297CTD
196PterygiumOFFSIDES
197PyelonephritisOFFSIDES
198Rash erythematousCanada Vigilance: 2Canada Vigilance
199Reaction gastrointestinalSIDER
200Reaction to drug excipientsSIDER
201Respiratory Insufficiency6416440CTD
202ReticulocytosisCanada Vigilance: 1Canada Vigilance
203Salmonella infections839647CTD
204Scrotal erythemaOFFSIDES
205Sepsis6071896CTD
206Skin reactionCanada Vigilance: 2Canada Vigilance
207Soft Tissue InjuriesOFFSIDES
208Stevens-Johnson SyndromeOFFSIDES
209StomatitisCanada Vigilance: 1Canada Vigilance
SIDER
210Subdural Effusion2041948CTD
211SwellingCanada Vigilance: 1Canada Vigilance
212ThoracotomyOFFSIDES
213Toxic anterior segment syndromeOFFSIDES
214Typhoid Fever3289662
4938432		CTD
SIDER
215UrticariaCanada Vigilance: 5Canada Vigilance
SIDER
216Vascular Diseases4825630CTD
217Vasomotor collapseSIDER
218Ventricular Dysfunction, Left1736269
7229771		CTD
219Vibration test abnormalOFFSIDES
220Viral upper respiratory tract infectionOFFSIDES
221VomitingSIDER
222Vulvovaginal pruritusCanada Vigilance: 1Canada Vigilance
223Waxy flexibilityOFFSIDES
224leukemia1211407
8834551
18559535		CTD
225nervous system disorderSIDER
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