MetaADEDB 2.0 @ LMMD
Diphenhydramine
(ZZVUWRFHKOJYTH-UHFFFAOYSA-N)
Structure
SMILES
CN(CCOC(c1ccccc1)c1ccccc1)C
Type(s)
Approved; Investigational
ATC code(s)
D04AA32; D04AA33; R06AA02; R06AA52
Molecular Formula:
C17H21NO
Molecular Weight:
255.355
Log P:
3.3542
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
0
TPSA:
12.47
CAS Number(s):
58-73-1; 147-24-0; 2122800-18-2
Synonym(s)
1.
Diphenhydramine
2.
Benhydramin
3.
Diphenylhydramin
4.
2-Diphenylmethoxy-N,N-dimethylethylamine
5.
Allerdryl
6.
Benadryl
7.
Benylin
8.
Benzhydramine
9.
Dimedrol
10.
Diphenhydramine Citrate
11.
Diphenhydramine Citrate (1:1)
12.
Diphenhydramine Hydrochloride
13.
Diphenylhydramine
14.
Dormin
15.
Citrate, Diphenhydramine
16.
Hydrochloride, Diphenhydramine
External Link(s)
MeSHD004155
PubChem Compound3100
BindingDB50017674
ChEBI4636
CHEMBLCHEMBL657
DrugBankDB01075
DrugCentral916
IUPHAR/BPS Guide to PHARMACOLOGY1224
KEGGcpd:C06960
dr:D00300
Therapeutic Target DatabaseD02AKO
D01FGR
ZINC20244
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Toxicity to various agentsFAERS: 140
Canada Vigilance: 1
Canada Vigilance
US FAERS
2OverdoseFAERS: 125
Canada Vigilance: 7
Canada Vigilance
US FAERS
3Completed SuicideFAERS: 96
Canada Vigilance: 15
Canada Vigilance
US FAERS
4SomnolenceFAERS: 50
Canada Vigilance: 15
Canada Vigilance
SIDER
US FAERS
5TachycardiaFAERS: 48
Canada Vigilance: 7
5694107
12369036
15749198
CTD
SIDER
Canada Vigilance
US FAERS
6HypersensitivityFAERS: 46
Canada Vigilance: 8
830291
7420640
7937288
CTD
Canada Vigilance
US FAERS
7Drug DependenceFAERS: 45
Canada Vigilance: 3
Canada Vigilance
US FAERS
8Cardiac ArrestFAERS: 43
Canada Vigilance: 2
Canada Vigilance
US FAERS
9DizzinessFAERS: 39
Canada Vigilance: 8
5694107CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
10Product quality issueFAERS: 38US FAERS
11TremorFAERS: 38
Canada Vigilance: 10
2735633
5694107
7937288
CTD
SIDER
Canada Vigilance
US FAERS
12Drug abuseFAERS: 36US FAERS
13VomitingFAERS: 36
Canada Vigilance: 7
3554086
16304666
CTD
SIDER
Canada Vigilance
US FAERS
14Accidental overdoseFAERS: 30
Canada Vigilance: 2
Canada Vigilance
US FAERS
15DeliriumFAERS: 30
Canada Vigilance: 2

View details

CTD
Canada Vigilance
US FAERS
16Product use in unapproved indicationFAERS: 30US FAERS
17Product use issueFAERS: 30US FAERS
18AgitationFAERS: 29
Canada Vigilance: 5
Canada Vigilance
SIDER
US FAERS
19HypotensionFAERS: 29
Canada Vigilance: 1

View details

CTD
SIDER
Canada Vigilance
US FAERS
20NauseaFAERS: 29
Canada Vigilance: 5
6196992
16304666
CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
21Respiratory arrestFAERS: 29
Canada Vigilance: 2
Canada Vigilance
US FAERS
22Incorrect dose administeredFAERS: 28OFFSIDES
US FAERS
23Intentional drug misuseFAERS: 25OFFSIDES
US FAERS
24UrticariaFAERS: 25
Canada Vigilance: 9
947035
2404434
12637407
CTD
SIDER
Canada Vigilance
US FAERS
25PruritusFAERS: 24
Canada Vigilance: 8

View details

CTD
Canada Vigilance
US FAERS
26MalaiseFAERS: 23
Canada Vigilance: 3
Canada Vigilance
US FAERS
27Feeling abnormalFAERS: 22SIDER
US FAERS
28Mental status changesFAERS: 21OFFSIDES
US FAERS
29Suicide attemptFAERS: 21US FAERS
30Accidental drug intake by childFAERS: 19US FAERS
31DependenceFAERS: 19OFFSIDES
US FAERS
32Medication ErrorFAERS: 19
Canada Vigilance: 3
Canada Vigilance
US FAERS
33Drug ineffectiveFAERS: 18
Canada Vigilance: 3
Canada Vigilance
US FAERS
34MydriasisFAERS: 18
Canada Vigilance: 7
Canada Vigilance
US FAERS
35Sinus TachycardiaFAERS: 18US FAERS
36HeadacheFAERS: 17
Canada Vigilance: 2
7420640CTD
SIDER
Canada Vigilance
US FAERS
37Accidental exposure to product by childFAERS: 16US FAERS
38Depressed Level of ConsciousnessFAERS: 16OFFSIDES
US FAERS
39Unresponsive to stimuliFAERS: 16OFFSIDES
US FAERS
40Wrong drug administeredFAERS: 16US FAERS
41PainFAERS: 15
Canada Vigilance: 1
9832659
17202008
CTD
OFFSIDES
Canada Vigilance
US FAERS
42Urinary RetentionFAERS: 15
Canada Vigilance: 2
15039480CTD
SIDER
Canada Vigilance
US FAERS
43Chest PainFAERS: 14
Canada Vigilance: 4
Canada Vigilance
OFFSIDES
US FAERS
44DysarthriaFAERS: 14
Canada Vigilance: 1
2735633
4144147
7937288
CTD
Canada Vigilance
US FAERS
45AstheniaFAERS: 13
Canada Vigilance: 2
Canada Vigilance
OFFSIDES
SIDER
US FAERS
46FlushingFAERS: 13
Canada Vigilance: 3
Canada Vigilance
US FAERS
47SwellingFAERS: 13
Canada Vigilance: 1
Canada Vigilance
US FAERS
48SyncopeFAERS: 13
Canada Vigilance: 2
Canada Vigilance
US FAERS
49Drug screen positiveFAERS: 12
Canada Vigilance: 2
Canada Vigilance
US FAERS
50Drug toxicityFAERS: 12US FAERS
51Lip swellingFAERS: 12
Canada Vigilance: 1
Canada Vigilance
US FAERS
52RhabdomyolysisFAERS: 1219458581CTD
US FAERS
53DisorientationFAERS: 11US FAERS
54ErythemaFAERS: 11US FAERS
55Intentional product misuseFAERS: 11US FAERS
56Memory impairmentFAERS: 11US FAERS
57Accidental exposure to productFAERS: 10US FAERS
58AnxietyFAERS: 10
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
59ChillsFAERS: 10
Canada Vigilance: 6
Canada Vigilance
SIDER
US FAERS
60DementiaFAERS: 10US FAERS
61Drug ineffective for unapproved indicationFAERS: 10
Canada Vigilance: 2
Canada Vigilance
US FAERS
62Pharmaceutical product complaintFAERS: 10US FAERS
63Ventricular arrhythmiaFAERS: 10US FAERS
64Anticholinergic SyndromeFAERS: 9
Canada Vigilance: 5
Canada Vigilance
US FAERS
65Drug withdrawal syndromeFAERS: 9US FAERS
66FatigueFAERS: 9
Canada Vigilance: 2
Canada Vigilance
OFFSIDES
SIDER
US FAERS
67HypersomniaFAERS: 9US FAERS
68Metabolic acidosisFAERS: 9US FAERS
69Muscle RigidityFAERS: 92735633
6823166
CTD
US FAERS
70Therapeutic response unexpectedFAERS: 9OFFSIDES
US FAERS
71Accidental exposureFAERS: 8US FAERS
72Anaphylactic shockFAERS: 8
Canada Vigilance: 1
Canada Vigilance
US FAERS
73Dry skinFAERS: 8US FAERS
74DysphoniaFAERS: 8
Canada Vigilance: 1
Canada Vigilance
US FAERS
75Expired drug administeredFAERS: 8US FAERS
76LethargyFAERS: 8OFFSIDES
US FAERS
77Status EpilepticusFAERS: 8US FAERS
78Unevaluable eventFAERS: 8US FAERS
79Altered state of consciousnessFAERS: 7US FAERS
80DehydrationFAERS: 7OFFSIDES
US FAERS
81DysuriaFAERS: 7US FAERS
82PalpitationsFAERS: 7
Canada Vigilance: 3
Canada Vigilance
SIDER
US FAERS
83ShockFAERS: 7US FAERS
84StaringFAERS: 7US FAERS
85AbasiaFAERS: 6US FAERS
86Blood glucose increasedFAERS: 6US FAERS
87Brain DeathFAERS: 6US FAERS
88Drug exposure during pregnancyFAERS: 6US FAERS
89IncoherentFAERS: 6
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
90Respiratory FailureFAERS: 6OFFSIDES
US FAERS
91Weight decreasedFAERS: 6US FAERS
92AmnesiaFAERS: 59600577
14614911
CTD
OFFSIDES
US FAERS
93AsthmaFAERS: 5US FAERS
94Atrial FibrillationFAERS: 5US FAERS
95BradycardiaFAERS: 56177211CTD
US FAERS
96Chest discomfortFAERS: 5SIDER
US FAERS
97CryingFAERS: 5US FAERS
98CyanosisFAERS: 5OFFSIDES
US FAERS
99Diabetes MellitusFAERS: 5US FAERS
100DiscomfortFAERS: 5
Canada Vigilance: 1
Canada Vigilance
US FAERS
101Euphoric moodFAERS: 5SIDER
US FAERS
102FormicationFAERS: 5US FAERS
103HypokinesiaFAERS: 5US FAERS
104HypoxiaFAERS: 5US FAERS
105Intentional misuseFAERS: 5US FAERS
106Maternal exposure during pregnancyFAERS: 5US FAERS
107Myocardial InfarctionFAERS: 5US FAERS
108PoisoningFAERS: 512460839CTD
US FAERS
109Rash erythematousFAERS: 5US FAERS
110Reduced facial expressionFAERS: 5US FAERS
111Respiratory DepressionFAERS: 5US FAERS
112RestlessnessFAERS: 5
Canada Vigilance: 2
Canada Vigilance
US FAERS
113VertigoFAERS: 5
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
114Visual disturbanceFAERS: 5US FAERS
115Abdominal PainFAERS: 4OFFSIDES
US FAERS
116AngioedemaFAERS: 4

View details

CTD
OFFSIDES
US FAERS
117AphasiaFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
118Aspartate Aminotransferase IncreasedFAERS: 4US FAERS
119Blood pH decreasedFAERS: 4US FAERS
120Cerebrovascular accidentFAERS: 4US FAERS
121Circumstance or information capable of leading to medication errorFAERS: 4US FAERS
122Drug abuserFAERS: 4US FAERS
123Drug level above therapeuticFAERS: 4US FAERS
124Hallucinations, mixedFAERS: 4US FAERS
125HyperreflexiaFAERS: 4US FAERS
126Intentional product use issueFAERS: 4US FAERS
127Muscle necrosisFAERS: 4US FAERS
128NystagmusFAERS: 4US FAERS
129PresyncopeFAERS: 4US FAERS
130Product label issueFAERS: 4US FAERS
131TinnitusFAERS: 4
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
132Victim of homicideFAERS: 4US FAERS
133AcidosisFAERS: 3OFFSIDES
US FAERS
134AgeusiaFAERS: 3US FAERS
135Agonal rhythmFAERS: 3US FAERS
136Application site burnFAERS: 3US FAERS
137ArthralgiaFAERS: 3
Canada Vigilance: 2
Canada Vigilance
US FAERS
138Blood alcohol increasedFAERS: 3US FAERS
139Burning sensationFAERS: 3US FAERS
140ChokingFAERS: 3US FAERS
141Cold sweatFAERS: 3
Canada Vigilance: 2
Canada Vigilance
US FAERS
142Disseminated Intravascular CoagulationFAERS: 3OFFSIDES
US FAERS
143Drug administered to patient of inappropriate ageFAERS: 3US FAERS
144Drug administration errorFAERS: 3OFFSIDES
US FAERS
145DysphemiaFAERS: 3US FAERS
146DystoniaFAERS: 3

View details

CTD
US FAERS
147Electrocardiogram abnormalFAERS: 3US FAERS
148EpistaxisFAERS: 3US FAERS
149Erectile dysfunctionFAERS: 3US FAERS
150Failure of child resistant mechanism for pharmaceutical productFAERS: 3US FAERS
151Feeling ColdFAERS: 3OFFSIDES
US FAERS
152Gaze palsyFAERS: 3US FAERS
153Hyporesponsive to stimuliFAERS: 3US FAERS
154Impaired work abilityFAERS: 3US FAERS
155Incorrect route of drug administrationFAERS: 3US FAERS
156Injection Site ReactionFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
157Injection site painFAERS: 3US FAERS
158Injection site warmthFAERS: 3US FAERS
159Medication residue presentFAERS: 3US FAERS
160Multiple allergiesFAERS: 3US FAERS
161No reaction on previous exposure to drugFAERS: 3OFFSIDES
US FAERS
162PolyuriaFAERS: 3OFFSIDES
US FAERS
163Poor quality drug administeredFAERS: 3US FAERS
164Pulmonary congestionFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
165Pupillary light reflex tests abnormalFAERS: 3US FAERS
166Reaction to drug excipientsFAERS: 3US FAERS
167Restless Legs SyndromeFAERS: 3US FAERS
168ScreamingFAERS: 3
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
169Skin irritationFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
170Sudden infant death syndromeFAERS: 3US FAERS
171Thermal burnFAERS: 3US FAERS
172Throat irritationFAERS: 3US FAERS
173Urinary tract infectionFAERS: 3US FAERS
174Ventricular FibrillationFAERS: 3OFFSIDES
US FAERS
175Wrong technique in drug usage processFAERS: 3US FAERS
176Acute kidney injuryFAERS: 219458581CTD
US FAERS
177Alanine Aminotransferase IncreasedFAERS: 2US FAERS
178AngerFAERS: 2US FAERS
179Anion GapFAERS: 2US FAERS
180Anion gap abnormalFAERS: 2US FAERS
181AnorexiaFAERS: 2OFFSIDES
SIDER
US FAERS
182AphagiaFAERS: 2US FAERS
183Application site drynessFAERS: 2US FAERS
184Application site painFAERS: 2US FAERS
185Application site scarFAERS: 2US FAERS
186ArthropathyFAERS: 2US FAERS
187AsphyxiaFAERS: 2US FAERS
188AtaxiaFAERS: 2
Canada Vigilance: 1
4221165
15746546
CTD
Canada Vigilance
US FAERS
189Back PainFAERS: 2US FAERS
190Blood creatine phosphokinase increasedFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
191Blood creatinine increasedFAERS: 2OFFSIDES
US FAERS
192BursitisFAERS: 2OFFSIDES
US FAERS
193Cardiovascular insufficiencyFAERS: 2US FAERS
194CholelithiasisFAERS: 2US FAERS
195ClonusFAERS: 2US FAERS
196Coma scale abnormalFAERS: 2US FAERS
197ConstipationFAERS: 2SIDER
US FAERS
198Drug level increasedFAERS: 2
Canada Vigilance: 12
Canada Vigilance
US FAERS
199EczemaFAERS: 2US FAERS
200ExophthalmosFAERS: 2US FAERS
201Food AllergyFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
202Gastrointestinal sounds abnormalFAERS: 2US FAERS
203Genital painFAERS: 2US FAERS
204HyperacusisFAERS: 2US FAERS
205HypoperfusionFAERS: 2US FAERS
206ImmobileFAERS: 2US FAERS
207Infusion site phlebitisFAERS: 2US FAERS
208Injection site necrosisFAERS: 2US FAERS
209Joint swellingFAERS: 2US FAERS
210Lipase increasedFAERS: 2US FAERS
211Mental impairmentFAERS: 2US FAERS
212Middle insomniaFAERS: 2US FAERS
213Musculoskeletal stiffnessFAERS: 2
Canada Vigilance: 2
Canada Vigilance
US FAERS
214NervousnessFAERS: 2SIDER
US FAERS
215No adverse effectFAERS: 2US FAERS
216Oropharyngeal swellingFAERS: 2US FAERS
217Oxygen saturation abnormalFAERS: 2US FAERS
218Panic DisorderFAERS: 2US FAERS
219ParanoiaFAERS: 2US FAERS
220Peptic Ulcer PerforationFAERS: 2
Canada Vigilance: 2
Canada Vigilance
US FAERS
221Pharyngolaryngeal PainFAERS: 2OFFSIDES
US FAERS
222PneumoniaFAERS: 2US FAERS
223Poor quality sleepFAERS: 2US FAERS
224Product contamination microbialFAERS: 2US FAERS
225Secretion dischargeFAERS: 2US FAERS
226Seizure like phenomenaFAERS: 2US FAERS
227StillbirthFAERS: 2US FAERS
228Therapy non-responderFAERS: 2OFFSIDES
US FAERS
229Tongue blisteringFAERS: 2US FAERS
230Urinary IncontinenceFAERS: 2US FAERS
231Vasoplegia syndromeFAERS: 2US FAERS
232Visual ImpairmentFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
233treatment failureFAERS: 2US FAERS
234Abdominal massFAERS: 1US FAERS
235Acquired Immunodeficiency SyndromeFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
236Activities of daily living impairedFAERS: 1US FAERS
237Acute respiratory failureFAERS: 1OFFSIDES
US FAERS
238Adverse eventFAERS: 1OFFSIDES
US FAERS
239AkathisiaFAERS: 1US FAERS
240Alcohol interactionFAERS: 1US FAERS
241AlopeciaFAERS: 1OFFSIDES
US FAERS
242Amphetamines positiveFAERS: 1US FAERS
243Anaphylactoid ReactionFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
244Angina PectorisFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
245AnhedoniaFAERS: 1US FAERS
246AnosmiaFAERS: 1OFFSIDES
US FAERS
247AnuriaFAERS: 1US FAERS
248Apallic syndromeFAERS: 1US FAERS
249Apparent deathFAERS: 1US FAERS
250Apparent life threatening eventFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
251AppendicitisFAERS: 1OFFSIDES
US FAERS
252Application site rashFAERS: 1US FAERS
253ArthritisFAERS: 1US FAERS
254AthetosisFAERS: 14144147CTD
US FAERS
255Atrioventricular BlockFAERS: 1US FAERS
256Back disorderFAERS: 1US FAERS
257Bacteria urine identifiedFAERS: 1US FAERS
258BlindnessFAERS: 1US FAERS
259Blood cholesterol increasedFAERS: 1US FAERS
260Blood creatine increasedFAERS: 1US FAERS
261Blood gases abnormalFAERS: 1US FAERS
262Blood glucose decreasedFAERS: 1OFFSIDES
US FAERS
263Blood lactate dehydrogenase increasedFAERS: 1US FAERS
264Blood pressure fluctuationFAERS: 1US FAERS
265Blood pressure immeasurableFAERS: 1US FAERS
266Blood sodium decreasedFAERS: 1US FAERS
267Brain scan abnormalFAERS: 1US FAERS
268Breath alcohol test positiveFAERS: 1US FAERS
269Bronchial secretion retentionFAERS: 1US FAERS
270BronchopneumoniaFAERS: 1US FAERS
271Buccal cavity papillomaFAERS: 1US FAERS
272CD8 lymphocytes decreasedFAERS: 1US FAERS
273Cardiac discomfortFAERS: 1US FAERS
274Cardiac infectionFAERS: 1US FAERS
275Cardiac perforationFAERS: 1US FAERS
276Carotid artery occlusionFAERS: 1US FAERS
277CellulitisFAERS: 1OFFSIDES
US FAERS
278Cerebral disorderFAERS: 1US FAERS
279CheilitisFAERS: 1US FAERS
280Choking sensationFAERS: 1OFFSIDES
US FAERS
281Contraindicated drug administeredFAERS: 1US FAERS
282CystitisFAERS: 1US FAERS
283Dark circles under eyesFAERS: 1US FAERS
284DeformityFAERS: 1US FAERS
285Depressed moodFAERS: 1US FAERS
286DermatitisFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
287Device related infectionFAERS: 1OFFSIDES
US FAERS
288Diabetic ulcerFAERS: 1US FAERS
289DroolingFAERS: 1US FAERS
290Dropped head syndromeFAERS: 1US FAERS
291Drug dispensing errorFAERS: 1US FAERS
292Drug diversionFAERS: 1US FAERS
293Drug dose omissionFAERS: 1US FAERS
294Drug screen false positiveFAERS: 1US FAERS
295Drug-disease interactionFAERS: 1US FAERS
296DysgeusiaFAERS: 1US FAERS
297DyspepsiaFAERS: 1
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
298Echocardiogram abnormalFAERS: 1US FAERS
299Electrocardiogram ST-T changeFAERS: 1US FAERS
300Electrocardiogram changeFAERS: 1US FAERS
301Electroencephalogram abnormalFAERS: 1US FAERS
302Electrolyte imbalanceFAERS: 1US FAERS
303Emotional disorderFAERS: 1US FAERS
304Emotional distressFAERS: 1OFFSIDES
US FAERS
305EpilepsyFAERS: 1US FAERS
306ExcitabilityFAERS: 1US FAERS
307Expired product administeredFAERS: 1
Canada Vigilance: 2
Canada Vigilance
US FAERS
308Exposure during breast feedingFAERS: 1US FAERS
309Exposure to toxic agentFAERS: 1US FAERS
310Exposure via ingestionFAERS: 1US FAERS
311Extra dose administeredFAERS: 1US FAERS
312Extraocular Muscle ParesisFAERS: 1US FAERS
313Extremity necrosisFAERS: 1US FAERS
314Eye InfectionFAERS: 1US FAERS
315Eye irritationFAERS: 1US FAERS
316Eye painFAERS: 1US FAERS
317Facial paralysisFAERS: 1US FAERS
318False positive laboratory resultFAERS: 1US FAERS
319Feeling jitteryFAERS: 1US FAERS
320Feeling of body temperature changeFAERS: 1US FAERS
321Fibrin D dimer increasedFAERS: 1US FAERS
322FlatulenceFAERS: 1US FAERS
323Foaming at mouthFAERS: 1US FAERS
324Gamma-Glutamyltransferase IncreasedFAERS: 1US FAERS
325GangreneFAERS: 1OFFSIDES
US FAERS
326Gastric DilatationFAERS: 1US FAERS
327GastritisFAERS: 1US FAERS
328Gastrointestinal hypomotilityFAERS: 1US FAERS
329General physical health deteriorationFAERS: 1
Canada Vigilance: 2
Canada Vigilance
US FAERS
330General symptomFAERS: 1US FAERS
331Genital burning sensationFAERS: 1US FAERS
332Genital discomfortFAERS: 1US FAERS
333Genital erythemaFAERS: 1US FAERS
334Genital swellingFAERS: 1US FAERS
335GlaucomaFAERS: 1US FAERS
336Head discomfortFAERS: 1US FAERS
337Heart sounds abnormalFAERS: 1US FAERS
338Heart-lung transplant rejectionFAERS: 1US FAERS
339HepatitisFAERS: 1US FAERS
340HepatotoxicityFAERS: 1US FAERS
341HomicideFAERS: 1US FAERS
342HyperchlorhydriaFAERS: 1US FAERS
343HyperlipasaemiaFAERS: 1US FAERS
344HyperventilationFAERS: 1US FAERS
345Hypoaesthesia facialFAERS: 1US FAERS
346HypometabolismFAERS: 1US FAERS
347IleusFAERS: 1US FAERS
348Impaired driving abilityFAERS: 1OFFSIDES
US FAERS
349Impaired gastric emptyingFAERS: 1OFFSIDES
US FAERS
350Impaired self-careFAERS: 1US FAERS
351Implant site infectionFAERS: 1US FAERS
352IncontinenceFAERS: 1OFFSIDES
US FAERS
353Incorrect drug administration rateFAERS: 1US FAERS
354Incorrect route of product administrationFAERS: 1US FAERS
355Increased upper airway secretionFAERS: 1US FAERS
356InfectionFAERS: 1US FAERS
357InflammationFAERS: 1US FAERS
358Initial insomniaFAERS: 1US FAERS
359Injury asphyxiationFAERS: 1US FAERS
360Intercepted drug dispensing errorFAERS: 1US FAERS
361LacerationFAERS: 1US FAERS
362Locked-In SyndromeFAERS: 1US FAERS
363LymphomaFAERS: 1US FAERS
364MalnutritionFAERS: 1US FAERS
365Maternal exposure during deliveryFAERS: 1US FAERS
366Medication tamperingFAERS: 1US FAERS
367MoaningFAERS: 1US FAERS
368Mood swingsFAERS: 1US FAERS
369Multiple SclerosisFAERS: 1OFFSIDES
US FAERS
370Multiple System AtrophyFAERS: 1US FAERS
371Muscle tightnessFAERS: 1OFFSIDES
US FAERS
372Musculoskeletal PainFAERS: 1US FAERS
373MutismFAERS: 1US FAERS
374MyoclonusFAERS: 1US FAERS
375Myoglobin blood increasedFAERS: 1US FAERS
376Myoglobin urine presentFAERS: 1US FAERS
377NecrosisFAERS: 18363115CTD
US FAERS
378NeuritisFAERS: 1SIDER
US FAERS
379Neurotransmitter level alteredFAERS: 1US FAERS
380Nonspecific reactionFAERS: 1US FAERS
381OligodipsiaFAERS: 1US FAERS
382Open woundFAERS: 1US FAERS
383Oropharyngeal spasmFAERS: 1US FAERS
384OsteoporosisFAERS: 1US FAERS
385PCO2 decreasedFAERS: 1US FAERS
386PO2 decreasedFAERS: 1US FAERS
387PallorFAERS: 1OFFSIDES
US FAERS
388PapillomaFAERS: 1US FAERS
389Peripheral swellingFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
390Personality ChangeFAERS: 1US FAERS
391Pharyngeal swellingFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
392PhotophobiaFAERS: 1US FAERS
393Post procedural complicationFAERS: 1US FAERS
394Postmortem blood drug level increasedFAERS: 1US FAERS
395Pressure of speechFAERS: 1US FAERS
396Procedural complicationFAERS: 1US FAERS
397Product closure issueFAERS: 1US FAERS
398Product formulation issueFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
399Product label confusionFAERS: 1US FAERS
400Product outer packaging issueFAERS: 1US FAERS
401Product package associated injuryFAERS: 1US FAERS
402Product packaging issueFAERS: 1US FAERS
403Product substitution issueFAERS: 1US FAERS
404Product tamperingFAERS: 1US FAERS
405Prostatic ObstructionFAERS: 1US FAERS
406Protein urine presentFAERS: 1US FAERS
407Reaction to excipientFAERS: 1US FAERS
408Reaction to preservativesFAERS: 1US FAERS
409Respiratory distressFAERS: 1US FAERS
410RetchingFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
411Rheumatoid ArthritisFAERS: 1US FAERS
412Right ventricular systolic pressure increasedFAERS: 1US FAERS
413SepsisFAERS: 1US FAERS
414Skin PapillomaFAERS: 1US FAERS
415Skin UlcerFAERS: 1US FAERS
416Skin lesionFAERS: 1US FAERS
417Skin reactionFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
418Slow speechFAERS: 1US FAERS
419Stevens-Johnson SyndromeFAERS: 1OFFSIDES
US FAERS
420Sudden deathFAERS: 1OFFSIDES
US FAERS
421Suprapubic painFAERS: 1US FAERS
422Supraventricular tachycardiaFAERS: 1US FAERS
423Systemic leakageFAERS: 1US FAERS
424Tablet issueFAERS: 1US FAERS
425Tardive DyskinesiaFAERS: 1OFFSIDES
US FAERS
426Tonic clonic movementsFAERS: 1US FAERS
427Tooth LossFAERS: 1US FAERS
428ToothacheFAERS: 1US FAERS
429Toxicologic test abnormalFAERS: 1US FAERS
430Transmission of an infectious agent via a medicinal productFAERS: 1US FAERS
431Traumatic Brain InjuryFAERS: 1US FAERS
432TrismusFAERS: 1830291
2735633
7937288
CTD
US FAERS
433UlcerFAERS: 1US FAERS
434Upper-airway cough syndromeFAERS: 1US FAERS
435Urinary hesitationFAERS: 1US FAERS
436Urine amphetamine positiveFAERS: 1US FAERS
437Vaginal burning sensationFAERS: 1US FAERS
438VasculitisFAERS: 1US FAERS
439Vitreous floatersFAERS: 1US FAERS
440WheezingFAERS: 1SIDER
US FAERS
441Wrong patient received medicationFAERS: 1US FAERS
442nervous system disorderFAERS: 1US FAERS
443skin abrasionFAERS: 1US FAERS
444Abdominal discomfortOFFSIDES
445Abdominal rigidityOFFSIDES
446Abdominal strangulated herniaOFFSIDES
447AbuseOFFSIDES
448Acute bronchitisOFFSIDES
449Acute graft versus host disease in liverOFFSIDES
450Acute myocardial infarctionOFFSIDES
451Adenomatous Polyposis ColiOFFSIDES
452AgoraphobiaOFFSIDES
453AgranulocytosisCanada Vigilance: 2Canada Vigilance
SIDER
454Airway Obstruction2233075
18651722
CTD
455Akathisia, Drug-Induced

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CTD
456Alcohol consumptionOFFSIDES
457AlveolitisOFFSIDES
458Anal FissureOFFSIDES
459AndropauseOFFSIDES
460Anemia12601542CTD
461Anoxic EncephalopathyOFFSIDES
462Anticonvulsant drug level decreasedOFFSIDES
463Antidepressant drug clearance increasedOFFSIDES
464Anxiety Disorders3415026
10770471
12409990
CTD
465ApathyOFFSIDES
466AphoniaCanada Vigilance: 1Canada Vigilance
467Application site vesiclesOFFSIDES
468Application site warmthOFFSIDES
469ArteriosclerosisOFFSIDES
470Arteriovenous fistula thrombosisOFFSIDES
471Aspiration PneumoniaOFFSIDES
472AtelectasisOFFSIDES
473Atrial tachycardiaOFFSIDES
474Bacterial culture positiveOFFSIDES
475Basal Ganglia Diseases

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CTD
476BelligerenceOFFSIDES
477Biliary dilatationOFFSIDES
478Bipolar DisorderOFFSIDES
479Blood osmolarity increasedOFFSIDES
480Blood phosphorus increasedOFFSIDES
481Blood potassium decreasedOFFSIDES
482Blood testosterone decreasedOFFSIDES
483Blood thyroid stimulating hormoneOFFSIDES
484Blood thyroid stimulating hormone increasedOFFSIDES
485Blood urine presentCanada Vigilance: 1Canada Vigilance
486Blunted affectOFFSIDES
487Blurred visionOFFSIDES
488BradyphreniaCanada Vigilance: 2Canada Vigilance
489Breast cancer stage IIIOFFSIDES
490BronchitisOFFSIDES
491BruxismOFFSIDES
492Cardiac enzymes increasedOFFSIDES
493Catalepsy6141553CTD
494CataractOFFSIDES
495Catatonia4477392CTD
496Catheter site infectionOFFSIDES
497Cerebellar artery thrombosisOFFSIDES
498Chemical and Drug Induced Liver Injury6886037CTD
499Chest tightnessSIDER
500Chronic Obstructive Airway DiseaseOFFSIDES
501Chronic respiratory failureOFFSIDES
502Chronic sinusitisOFFSIDES
503CirrhosisOFFSIDES
504Clostridium difficile colitisOFFSIDES
505Cognition Disorders

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CTD
506ColitisOFFSIDES
507Colon adenomaOFFSIDES
508Common Cold8407755CTD
509Compulsive shoppingOFFSIDES
510Conduct Disorder14742796CTD
511Confusion947035
2735633
5694107
CTD
512Conjunctival depositOFFSIDES
513Consciousness Disorders242240
7937288
CTD
514Contact DermatitisOFFSIDES
515Culture positiveOFFSIDES
516Deglutition Disorders2735633CTD
517Developmental Coordination DisorderOFFSIDES
518DiabetesOFFSIDES
519Diabetes mellitus inadequate controlOFFSIDES
520DiarrheaOFFSIDES
521DiplopiaCanada Vigilance: 17420640CTD
SIDER
Canada Vigilance
522Disorders of Excessive Somnolence

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CTD
523DrowsinessOFFSIDES
SIDER
524Drug Eruptions464432
7091988
CTD
525Drug Overdose12369036
15749198
CTD
526Drug level fluctuatingOFFSIDES
527Drug withdrawal headacheOFFSIDES
528Dyskinesia, Drug-Induced830291
947035
1147302
CTD
529Dysthymic DisorderOFFSIDES
530Edema947035
9274987
CTD
531Electromechanical dissociationOFFSIDES
532Endometrial Neoplasms12601542CTD
533Endometrial cancer stage IIOFFSIDES
534Engraftment syndromeOFFSIDES
535Epigastric distressSIDER
536Erythema MultiformeOFFSIDES
537Exanthema7196160CTD
538Exposure via breast milkCanada Vigilance: 1Canada Vigilance
539Eye inflammationCanada Vigilance: 1Canada Vigilance
540Facial Nerve Diseases9250654CTD
541Failure to ThriveOFFSIDES
542Febrile NeutropeniaOFFSIDES
543Fetal Diseases8012899CTD
544Fever10225031CTD
545Flank PainOFFSIDES
546Fluid overloadOFFSIDES
547Gait Disorders, Neurologic4221165CTD
548GamblingOFFSIDES
549Gastric hypermotilityOFFSIDES
550Gastric ulcerOFFSIDES
551Glioblastoma MultiformeOFFSIDES
552GranulocytosisOFFSIDES
553Hallucinations

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CTD
554Heart failure3378606CTD
555Heat Stroke12190212CTD
556HemiparesisOFFSIDES
557Heparin-induced thrombocytopeniaOFFSIDES
558Hepatic vein occlusionOFFSIDES
559Hepatitis AOFFSIDES
560Hepatitis BOFFSIDES
561Hepatitis COFFSIDES
562HepatosplenomegalyOFFSIDES
563HiccoughOFFSIDES
564Hyperalgesia19038771CTD
565Hyperglycemia17026994CTD
566Hypesthesia19458581CTD
567Hypoglycemia2414028CTD
568Hypokalemia7497894CTD
569HysterectomyOFFSIDES
570IleitisOFFSIDES
571ImmunosuppressionOFFSIDES
572Implant site reactionOFFSIDES
573Inappropriate affectCanada Vigilance: 1Canada Vigilance
574Injection site coldnessOFFSIDES
575Injection site erythemaOFFSIDES
576Injection site inflammationCanada Vigilance: 5Canada Vigilance
577Injection site pruritusOFFSIDES
578Injection site urticariaOFFSIDES
579Intention tremorOFFSIDES
580Kidney FailureOFFSIDES
581Klebsiella sepsisOFFSIDES
582LabyrinthitisSIDER
583Laryngeal Diseases2330407CTD
584LaryngospasmCanada Vigilance: 1Canada Vigilance
585Left atrial dilatationOFFSIDES
586Leukopenia neonatalOFFSIDES
587LeukopeniaCanada Vigilance: 212601542CTD
Canada Vigilance
588Listeria sepsisOFFSIDES
589Liver Failure, Acute18986731CTD
590Long QT Syndrome15749198
24052561
25822712
CTD
591Lung InjuryOFFSIDES
592Malignant HypertensionOFFSIDES
593Malignant neoplasm progressionOFFSIDES
594MeningiomaOFFSIDES
595MetaplasiaOFFSIDES
596Migraine Disorders20045576CTD
597Mood Disorders5095411CTD
598Mood disorder due to a general medical conditionOFFSIDES
599Motor Skills Disorders2735633CTD
600Mouth swellingCanada Vigilance: 1Canada Vigilance
601Movement Disorders7492048
19519270
CTD
602Multi-organ disorderOFFSIDES
603Muscle SpasticityCanada Vigilance: 1Canada Vigilance
604NasopharyngitisOFFSIDES
605Nephrogenic Fibrosing DermopathyOFFSIDES
606Nervous tensionOFFSIDES
607Neurobehavioral Manifestations12369036CTD
608Neuroleptic Malignant Syndrome16669738CTD
609Neutropenia12601542CTD
610Neutropenic sepsisOFFSIDES
611Neutrophil count decreasedOFFSIDES
612Nicotine DependenceOFFSIDES
613NoduleOFFSIDES
614Ocular Motility Disorders

View details

CTD
615Oliguria19458581CTD
616Open reduction of fractureOFFSIDES
617Oropharyngeal painOFFSIDES
618OrthopneaOFFSIDES
619Pancreatic PseudocystOFFSIDES
620PancreatitisOFFSIDES
621Pericardial effusionOFFSIDES
622Peripheral Nervous System Diseases12601542CTD
623Peripheral occlusive diseaseOFFSIDES
624Perirectal abscessOFFSIDES
625PeritonsillitisOFFSIDES
626PhlebitisCanada Vigilance: 3Canada Vigilance
627Poor sucking reflexOFFSIDES
628Post procedural infectionOFFSIDES
629Product administration errorCanada Vigilance: 1Canada Vigilance
630Psychomotor Agitation242240CTD
631Psychomotor Disorders12352276CTD
632Psychoses, Substance-Induced

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CTD
633Pulmonary HypertensionOFFSIDES
634Renal cystOFFSIDES
635Renal tubular necrosisOFFSIDES
636RhonchiOFFSIDES
637Seizures

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CTD
638Semen volume decreasedOFFSIDES
639Septic ShockOFFSIDES
640Serum SicknessOFFSIDES
641Sinusitis12637407CTD
642Skeletal injuryOFFSIDES
643Sleep Initiation and Maintenance Disorders18344728
19458581
CTD
644Sleep TalkingOFFSIDES
645Sneezing8100058CTD
646Soft Tissue InjuriesOFFSIDES
647Somnambulism453369CTD
648Spasm4144147
4180232
CTD
649Speech Disorders

View details

CTD
650Splenic InfarctionOFFSIDES
651Status AsthmaticusCanada Vigilance: 1Canada Vigilance
652StressOFFSIDES
653Subcutaneous EmphysemaOFFSIDES
654Substance Withdrawal Syndrome66559
10225031
20193724
CTD
655TensionSIDER
656ThrombocytopeniaSIDER
657TineaOFFSIDES
658Tobacco userOFFSIDES
659TonsillitisOFFSIDES
660Torticollis

View details

CTD
661Tracheal StenosisOFFSIDES
662Ultrasound pelvisOFFSIDES
663Urinary tract infection fungalOFFSIDES
664Vasculitis, Leukocytoclastic, Cutaneous4221165CTD
665Venoocclusive diseaseOFFSIDES
666Voice Disorders15086036CTD
667Water PollutionOFFSIDES
668Wrong patient received productCanada Vigilance: 1Canada Vigilance
669XerosisOFFSIDES
670Xerostomia5694107
17092978
CTD
671melanoma16569656CTD
672muscle injuryOFFSIDES
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