MetaADEDB 2.0 @ LMMD
Procainamide
(REQCZEXYDRLIBE-UHFFFAOYSA-N)
Structure
SMILES
CCN(CCNC(=O)c1ccc(cc1)N)CC
Type(s)
Approved
ATC code(s)
C01BA02
Molecular Formula:
C13H21N3O
Molecular Weight:
235.325
Log P:
2.3125
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
58.36
CAS Number(s):
51-06-9; 614-39-1; 18788
Synonym(s)
1.
Procainamide
2.
Procaine Amide
3.
Apo-Procainamide
4.
Biocoryl
5.
Novocainamide
6.
Novocamid
7.
Procainamide Hydrochloride
8.
Procamide
9.
Procan
10.
Procan SR
11.
Procanbid
12.
Pronestyl
13.
Rhythmin
14.
Amide, Procaine
15.
Hydrochloride, Procainamide
External Link(s)
MeSHD011342
PubChem Compound4913
BindingDB39344
50059898
ChEBI8428
CHEMBLCHEMBL640
DrugBankDB01035
DrugCentral2270
IUPHAR/BPS Guide to PHARMACOLOGY4811
KEGGcpd:C07401
dr:D08421
Therapeutic Target DatabaseD0U5SI
ZINC1530756
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Sudden Cardiac DeathFAERS: 3US FAERS
2Drug ineffectiveFAERS: 2US FAERS
3Electrocardiogram repolarisation abnormalityFAERS: 2US FAERS
4Lupus-like syndromeFAERS: 2SIDER
US FAERS
5SyncopeFAERS: 2US FAERS
6Drug dose omissionFAERS: 1US FAERS
7NauseaFAERS: 1
Canada Vigilance: 8		1098684
4817707		CTD
SIDER
Canada Vigilance
US FAERS
8Therapeutic response unexpected with drug substitutionFAERS: 1US FAERS
9Abdominal PainSIDER
10Abdominal discomfortCanada Vigilance: 1Canada Vigilance
SIDER
11Acidosis, Lactic3155037CTD
12Agranulocytosis694426CTD
SIDER
13Anemia, Hemolytic417435
6858967		CTD
14Anemia694426CTD
15AngioedemaCanada Vigilance: 33971860CTD
SIDER
Canada Vigilance
16Anorexia4517705CTD
SIDER
17ArthralgiaCanada Vigilance: 84122729CTD
SIDER
Canada Vigilance
18ArthritisCanada Vigilance: 1Canada Vigilance
SIDER
19Aspartate Aminotransferase IncreasedCanada Vigilance: 1Canada Vigilance
20AstheniaCanada Vigilance: 2Canada Vigilance
SIDER
21Atrial FibrillationCanada Vigilance: 13713755
9607135
12620943		CTD
SIDER
Canada Vigilance
22Atrial Flutter

View details

2036596
7687390
7784240
11329104
11942585
 		CTD
23Atrial tachycardiaSIDER
24Atrioventricular Block2462213CTD
25Autoimmune Diseases9668287CTD
26Bipolar Disorder3337281CTD
27Blood Coagulation Disorders3142154CTD
28Blood creatinine decreasedSIDER
29BradycardiaCanada Vigilance: 26175805CTD
SIDER
Canada Vigilance
30Bundle-Branch Block679762
817046		CTD
31Cardiac ArrestCanada Vigilance: 1Canada Vigilance
SIDER
32Cerebellar Ataxia6497531CTD
33Chest PainCanada Vigilance: 33713755CTD
Canada Vigilance
34ChillsCanada Vigilance: 12Canada Vigilance
SIDER
35Coronary Artery Disease5015024CTD
36Creatinine lowSIDER
37Deglutition Disorders7687390CTD
38Delirium4188133CTD
39Diarrhea4817707CTD
40DiscomfortSIDER
41Disseminated Intravascular Coagulation10589462CTD
42DizzinessCanada Vigilance: 24817707CTD
SIDER
Canada Vigilance
43Drug Eruptions2973973
10589462		CTD
44Drug level increasedCanada Vigilance: 1Canada Vigilance
45Drug-induced lupus erythematosusSIDER
46DysgeusiaSIDER
47Dyspnea3713755CTD
48Electrocardiogram QRS complexSIDER
49Electrocardiogram abnormalCanada Vigilance: 1Canada Vigilance
50Electrocardiogram changeSIDER
51EosinophiliaCanada Vigilance: 1Canada Vigilance
SIDER
52ErythemaCanada Vigilance: 2Canada Vigilance
53Exanthema4122729CTD
54FatigueCanada Vigilance: 14817707CTD
Canada Vigilance
55Feeling abnormalSIDER
56Fever455820
4122729
4517705		CTD
57FlushingSIDER
58Gastrointestinal PainSIDER
59Glomerulonephritis95811
2940667
7015825		CTD
60Hallucinations4817707CTD
61HeadacheCanada Vigilance: 24122729CTD
Canada Vigilance
62Heart Block75367CTD
63Heart failure3155037
4042115
12519739		CTD
64HemiparesisCanada Vigilance: 1Canada Vigilance
65HepatomegalySIDER
66HypersensitivitySIDER
67Hypotension, Orthostatic4122729CTD
68HypotensionCanada Vigilance: 2

View details

509999
1098684
1860187
4053522
4371992
6175805
7154501
10496451
20370763
 		CTD
SIDER
Canada Vigilance
69HypotensiveSIDER
70Jaundice, Obstructive8477118CTD
71LethargySIDER
72LeukocytosisCanada Vigilance: 1Canada Vigilance
73LeukopeniaCanada Vigilance: 1Canada Vigilance
74LightheadednessSIDER
75Long QT Syndrome10217665
16178046		CTD
76Lupus Erythematosus, Cutaneous3769245CTD
77Lupus Erythematosus, Systemic

View details

19187
68769
95811
617255
921427
2940667
4517705
4781063
5015024
5031767
6155782
6159783
6261406
6858967
7015825
15286391
 		CTD
78Lupus ErythematosusSIDER
79Lupus Nephritis455820
9774137		CTD
80MalaiseCanada Vigilance: 5Canada Vigilance
SIDER
81Muscle Weakness

View details

2712073
3762585
6263235
7687390
 		CTD
82Musculoskeletal discomfortSIDER
83MyalgiaCanada Vigilance: 2Canada Vigilance
SIDER
84Myasthenia Gravis8236002CTD
85Myocardial InfarctionCanada Vigilance: 11098684CTD
Canada Vigilance
86Myocarditis6642765CTD
87Myoclonus3762585CTD
88Myositis7359164CTD
89Necrosis8328751CTD
90Nephrotic Syndrome455820CTD
91Neuromuscular Diseases3762585CTD
92NeutropeniaSIDER
93OliguriaSIDER
94PainCanada Vigilance: 1Canada Vigilance
95Paroxysmal atrial tachycardiaSIDER
96Pericardial effusionCanada Vigilance: 1

View details

921427
4781063
5053150
6155782
 		CTD
Canada Vigilance
97PericarditisCanada Vigilance: 1455820
4517705
5015024		CTD
SIDER
Canada Vigilance
98Peripheral Nervous System Diseases6261406CTD
99PleurisyCanada Vigilance: 14517705CTD
Canada Vigilance
100Pleuritic painCanada Vigilance: 1Canada Vigilance
101PneumonitisCanada Vigilance: 1Canada Vigilance
102Polyradiculoneuropathy, Chronic Inflammatory Demyelinating9521292CTD
103Polyradiculoneuropathy617255CTD
104Proteinuria7015825CTD
105Prothrombin level decreasedCanada Vigilance: 1Canada Vigilance
106PruritusCanada Vigilance: 2Canada Vigilance
SIDER
107Psychoses, Substance-Induced567255
6498664		CTD
108Rash erythematousCanada Vigilance: 6Canada Vigilance
109Renal Insufficiency7015825CTD
110Respiratory Insufficiency2842116CTD
111Respiratory Paralysis2712073CTD
112Rheumatoid ArthritisCanada Vigilance: 2Canada Vigilance
113Right upper quadrant painSIDER
114Shock, Cardiogenic7154501CTD
115ShockSIDER
116Sinus rhythmCanada Vigilance: 1Canada Vigilance
117Sleep Initiation and Maintenance Disorders4817707CTD
118Supraventricular tachycardiaSIDER
119SynovitisCanada Vigilance: 1Canada Vigilance
120Systemic lupus erythematosus rashCanada Vigilance: 2Canada Vigilance
121Tachycardia, Paroxysmal799549CTD
122Tachycardia, Ventricular

View details

1707220
2406361
2420424
2433319
2480708
2623834
3081184
3486933
3762585
3799443
5041936
6465015
6497531
7234705
7817931
8417082
10217665
10589462
10944996
13172862
15566921
20370763
 		CTD
123Tachycardia

View details

688720
2429270
3806932
4835257
6017018
6486026
6847803
 		CTD
124ThrombocytopeniaSIDER
125Thrombocytopenic purpuraCanada Vigilance: 1Canada Vigilance
126Thrombosis3124275CTD
127TinnitusCanada Vigilance: 1Canada Vigilance
128Torsades de Pointes

View details

1423949
2416504
6695782
7784240
7817931
8055145
8230644
9141970
10217665
16178046
 		CTD
129TremorCanada Vigilance: 32418674CTD
Canada Vigilance
130UrticariaCanada Vigilance: 42973973CTD
SIDER
Canada Vigilance
131Vasculitis, Leukocytoclastic, Cutaneous2973973CTD
132Vasculitis3769245
5649364
6023008		CTD
SIDER
133Ventricular Fibrillation

View details

509999
2726785
3081184
3393179
3704313
4966361
6193348
7817931
 		CTD
SIDER
134Ventricular arrhythmiaCanada Vigilance: 1Canada Vigilance
135VomitingCanada Vigilance: 51098684CTD
SIDER
Canada Vigilance
136Weight decreasedCanada Vigilance: 1Canada Vigilance
137Wolff-Parkinson-White Syndrome4835257CTD
138pH urine decreasedSIDER
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