MetaADEDB 2.0 @ LMMD
Carbimazole
(CFOYWRHIYXMDOT-UHFFFAOYSA-N)
Structure
SMILES
CCOC(=O)n1ccn(c1=S)C
Type(s)
Approved; Investigational
ATC code(s)
H03BB01
Molecular Formula:
C7H10N2O2S
Molecular Weight:
186.231
Log P:
1.5607
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
0
TPSA:
68.25
CAS Number(s):
22232-54-8
Synonym(s)
1.
Carbimazole
2.
Carbimazole Henning
3.
Neo Tomizol
4.
Neo-Mercazole
5.
Neo-Thyreostat
6.
Neomercazole
External Link(s)
MeSHD002231
PubChem Compound31072
BindingDB50275889
ChEBI617099
CHEMBLCHEMBL508102
DrugBankDB00389
DrugCentral497
KEGGcpd:C07615
dr:D07616
Therapeutic Target DatabaseD02CKX
ZINC1091
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal Pain3968675CTD
2Abdominal tendernessOFFSIDES
3Abnormalities, Drug-Induced9450891CTD
4AgeusiaSIDER
5AgranulocytosisCanada Vigilance: 14172680
18816182
20587933		CTD
SIDER
Canada Vigilance
6AlopeciaSIDER
7AlveolitisOFFSIDES
8Amyopathic dermatomyositis17986297CTD
9Anemia10848805CTD
10AngerOFFSIDES
11AngioedemaSIDER
12Anti-Glomerular Basement Membrane Disease3587472CTD
13Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis8542214
19263707		CTD
14Antipsychotic drug level increasedOFFSIDES
15ApathyOFFSIDES
16Arteriovenous fistula thrombosisOFFSIDES
17Arthralgia2565460
15785249
17986297		CTD
SIDER
18Arthritis15785249
19263707		CTD
19AscitesOFFSIDES
20Asthenia17986297CTD
21Asthma3968675CTD
22Basal cell carcinomaOFFSIDES
23Bipolar DisorderOFFSIDES
24Blood and lymphatic system disordersSIDER
25Blood magnesium decreasedOFFSIDES
26Blood sodium increasedOFFSIDES
27Blunted affectOFFSIDES
28Bone marrow depressionSIDER
29Burning sensationOFFSIDES
30Capillary Leak SyndromeOFFSIDES
31Cardiovascular insufficiencyOFFSIDES
32Cerebral AtherosclerosisOFFSIDES
33Cerebral atrophyOFFSIDES
34Cerebrovascular InsufficiencyOFFSIDES
35Chemical and Drug Induced Liver Injury

View details

2646363
2682839
3718146
4026479
7504976
8223196
8724032
12201214
12549952
20587933
 		CTD
36Choanal Atresia9450891
12124735		CTD
37Cholestasis

View details

2646363
2682839
3718146
4026479
7504976
12201214
20587933
 		CTD
38Chronic active hepatitisOFFSIDES
39Chronic left ventricular failureOFFSIDES
40Circumstance or information capable of leading to medication errorOFFSIDES
41ConfabulationOFFSIDES
42Consciousness fluctuatingOFFSIDES
43Craniofacial Abnormalities9450891CTD
44Depressed Level of ConsciousnessOFFSIDES
45Depressed moodOFFSIDES
46DermatitisSIDER
47Developmental Disabilities9450891CTD
48Diabetes mellitus inadequate controlOFFSIDES
49DiscomfortSIDER
50DistressSIDER
51Drug exposure during pregnancyOFFSIDES
52DyslogiaOFFSIDES
53DysphemiaOFFSIDES
54DystoniaOFFSIDES
55Electrocardiogram QT corrected intervalOFFSIDES
56Electromechanical dissociationOFFSIDES
57Emotional distressSIDER
58End Stage Liver Disease8724032CTD
59EosinophiliaSIDER
60Erythema Nodosum12201214CTD
61Erythema17986297CTD
62Euthyroid Sick Syndromes8542214CTD
63Exanthema2565460
15785249		CTD
64Feeding and Eating Disorders8223196CTD
65Feeling abnormalSIDER
66Fever15785249
19263707		CTD
67FilariasisOFFSIDES
68General physical health deteriorationOFFSIDES
69Glomerulonephritis8542214
15785249		CTD
70GoiterOFFSIDES
71Graves Disease

View details

1681385
7950664
9450891
12201214
16018796
19263707
 		CTD
72Grip strengthOFFSIDES
73HeadacheSIDER
74Hearing Loss7950664
21127764		CTD
75Hemorrhage15785249CTD
76Hepatic Encephalopathy8724032CTD
77Hepatitis AOFFSIDES
78Hepatitis B positiveOFFSIDES
79Hepatitis BOFFSIDES
80Hepatitis8724032CTD
OFFSIDES
SIDER
81Hepatomegaly3718146CTD
82HepatotoxicityOFFSIDES
83HypercapniaOFFSIDES
84HyperpigmentationOFFSIDES
85HypersensitivitySIDER
86Hyperthyroidism

View details

2646363
3544631
4186442
8223196
8542214
8724032
12549952
17986297
20587933
 		CTD
87HypogeusiaSIDER
88HypoparathyroidismOFFSIDES
89HyporeflexiaOFFSIDES
90Hypothyroidism4186442CTD
91Illogical thinkingOFFSIDES
92Impaired self-careOFFSIDES
93InfectionSIDER
94Intention tremorOFFSIDES
95Jaundice, Obstructive3968675CTD
96Kidney FailureOFFSIDES
97LethargyOFFSIDES
98LeukopeniaSIDER
99Liver Failure8223196
12549952		CTD
100Lung diseases15785249CTD
101MalaiseSIDER
102Mallory-Weiss SyndromeOFFSIDES
103Mononucleosis heterophile test positiveOFFSIDES
104Muscle Weakness17986297CTD
OFFSIDES
105Musculoskeletal chest painOFFSIDES
106Musculoskeletal discomfortSIDER
107Musculoskeletal stiffnessOFFSIDES
108MyalgiaSIDER
109MyopathySIDER
110Myositis1681385
2565460		CTD
111Narcotic intoxicationOFFSIDES
112Nausea2565460
3718146		CTD
SIDER
113NegativismOFFSIDES
114Nephritis, Interstitial12543903CTD
115Nephrogenic Diabetes InsipidusOFFSIDES
116Neutropenia10848805CTD
SIDER
117Neutropenic sepsisOFFSIDES
118Oropharyngeal discomfortSIDER
119Oropharyngeal painOFFSIDES
SIDER
120OrthopneaOFFSIDES
121OsteomyelitisOFFSIDES
122Pancreatitis12201214CTD
123PancytopeniaSIDER
124Paranoid Personality DisorderOFFSIDES
125Parotitis19263707CTD
126Peripheral embolismOFFSIDES
127PolyneuropathyOFFSIDES
128Prenatal Exposure Delayed Effects9450891
12124735		CTD
129Pruritus2565460CTD
SIDER
130Psychoses, Substance-Induced4186442CTD
131PurulenceOFFSIDES
132QuadriparesisOFFSIDES
133RhabdomyolysisOFFSIDES
134SchizophreniaOFFSIDES
135Spleen scan abnormalOFFSIDES
136StomatitisSIDER
137StubbornnessOFFSIDES
138Thrombocytopenia10848805CTD
SIDER
139ThyroiditisOFFSIDES
140Thyrotoxicosis6548829
8542214
14530534		CTD
141Tinnitus7950664
21127764		CTD
142Tobacco Use Disorder12549952CTD
143Torsades de Pointes11707056CTD
144Urticaria15785249CTD
SIDER
145Vanishing bile duct syndromeOFFSIDES
146Vasculitis, Leukocytoclastic, Cutaneous10327480
12543903		CTD
147Vasculitis1681385CTD
148Vocal Cord ParalysisOFFSIDES
149Vomiting3718146CTD
150White blood cell count abnormalOFFSIDES
151Wound DebridementOFFSIDES
152Wrong drug administeredOFFSIDES
153insulinomaOFFSIDES
154jaundice3718146
4026479
8724032		CTD
SIDER
155nervous system disorderSIDER
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