MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Glutathione

(RWSXRVCMGQZWBV-WDSKDSINSA-N)

Structure

SMILES: SC[C@@H](C(=O)NCC(=O)O)NC(=O)CC[C@@H](C(=O)O)N
Type(s): Approved; Investigational; Nutraceutical
ATC code(s): V03AB32
Molecular Formula:: C10H17N3O6S
Molecular Weight:: 307.323
Log P:: -0.7240
Hydrogen Bond Acceptor:: 10
Hydrogen Bond Donor:: 6
TPSA:: 197.62
CAS Number(s):: 70-18-8; 98726-08-0

Synonym(s)

Glutathione

Reduced Glutathione

gamma-L-Glu-L-Cys-Gly

gamma-L-Glutamyl-L-Cysteinylglycine

Glutathione, Reduced

gamma L Glu L Cys Gly

gamma L Glutamyl L Cysteinylglycine

External Link(s)

MeSH	D005978
PubChem Compound	124886 25246407
BindingDB	50422268
ChEBI	60836 16856
CHEMBL	CHEMBL1543
DrugBank	DB00143
DrugCentral	1312
IUPHAR/BPS Guide to PHARMACOLOGY	6737
KEGG	cpd:C00051 cpd:C02471 dr:D00014
Therapeutic Target Database	D02HFD
ZINC	3830891

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Abscess of eyelid			OFFSIDES
2	Activities of daily living impaired			OFFSIDES
3	Acute Coronary Syndrome			OFFSIDES
4	Acute kidney injury		10729747	CTD
5	Agraphia			OFFSIDES
6	Alanine Aminotransferase Increased			OFFSIDES
7	Altered state of consciousness			OFFSIDES
8	Amnesia		14643852	CTD
9	Amphetamines			OFFSIDES
10	Anorexia			OFFSIDES
11	Anti-insulin antibody positive			OFFSIDES
12	Anticonvulsant drug level decreased			OFFSIDES
13	Apathy			OFFSIDES
14	Appendicitis			OFFSIDES
15	Asthma		22867017	CTD OFFSIDES
16	Atrioventricular Block			OFFSIDES
17	Autistic Disorder		View details 16917939 18929414 19056591 19267885 24676906	CTD
18	Basal cell carcinoma			OFFSIDES
19	Benign neoplasm of bladder			OFFSIDES
20	Blood alkaline phosphatase increased			OFFSIDES
21	Blood creatine phosphokinase increased			OFFSIDES
22	Blood immunoglobulin E			OFFSIDES
23	Blood lactate dehydrogenase increased			OFFSIDES
24	Blood uric acid			OFFSIDES
25	Cardiomyopathies		1914080 2074045	CTD
26	Chemical and Drug Induced Liver Injury		View details 17584759 22310181 23333575 25743375	CTD
27	Choking sensation			OFFSIDES
28	Cholangiolitis			OFFSIDES
29	Cholestasis, Extrahepatic		30026087	CTD
30	Cholestasis		8377599	CTD
31	Chromaturia			OFFSIDES
32	Cirrhosis			OFFSIDES
33	Cognition Disorders		View details 11212865 18208924 18343489 19464315	CTD
34	Colitis		23810507	CTD
35	Corneal Ulcer			OFFSIDES
36	Cystic Fibrosis		19747007	CTD
37	Cystitis		16708234 24550594	CTD
38	Deafness			OFFSIDES
39	Depressed Level of Consciousness			OFFSIDES
40	Dermatitis		31330126	CTD
41	Diabetes			OFFSIDES
42	Diabetic Foot		11983006	CTD
43	Disease Progression			OFFSIDES
44	Drug toxicity			OFFSIDES
45	Dyskinesia, Drug-Induced		24406377	CTD
46	Edema		19874808 24550594	CTD
47	Epstein-Barr virus associated lymphoproliferative disorder			OFFSIDES
48	Exanthema		8377599	CTD
49	Fanconi Anemia		22628295	CTD
50	Fatty Liver		10860543	CTD
51	Fever		8377599	CTD
52	Gamma-Glutamyltransferase Increased			OFFSIDES
53	Gastrointestinal Diseases		9199886	CTD
54	Gastropleural fistula			OFFSIDES
55	Gaze palsy			OFFSIDES
56	Heart Diseases		10887039	CTD
57	Hematuria		2773078	CTD
58	Hemorrhage		16708234 24550594	CTD
59	Hepatic Insufficiency		30026087	CTD
60	Hepatic vein occlusion			OFFSIDES
61	Hepatitis B			OFFSIDES
62	Hepatomegaly		30026087	CTD
63	Histiocytosis haematophagic			OFFSIDES
64	Hyperhomocysteinemia		20413874	CTD
65	Hyperthyroidism		19914224	CTD
66	Hypoxia			OFFSIDES
67	Incontinence			OFFSIDES
68	Injection site discomfort	Canada Vigilance: 1		Canada Vigilance
69	Injection site erythema			OFFSIDES
70	Injection site pruritus			OFFSIDES
71	Intestinal Obstruction			OFFSIDES
72	Kidney Calculi		24360074	CTD
73	Kidney Diseases		1724173 2344991 18536492	CTD
74	Leukopenia neonatal			OFFSIDES
75	Liver Cirrhosis, Experimental		15962377	CTD
76	Liver neoplasms		7852184	CTD
77	Lymphocyte stimulation test positive			OFFSIDES
78	MELAS Syndrome		11907800	CTD
79	Memory Disorders		20871768	CTD
80	Mercury Poisoning, Nervous System		8806884	CTD
81	Mercury Poisoning		18536492	CTD
82	Methemoglobinemia		1308751	CTD
83	Movement Disorders		20833709	CTD
84	Multiple Sclerosis			OFFSIDES
85	Myopia			OFFSIDES
86	Necrosis		10753958	CTD
87	Neurotoxicity Syndromes		20696200	CTD
88	Obesity		23956348	CTD
89	Occupational Diseases		23791970	CTD
90	Oculomucocutaneous syndrome			OFFSIDES
91	Oliguria			OFFSIDES
92	Overdose			OFFSIDES
93	PROTHROMBIN TIME			OFFSIDES
94	Pericardial effusion			OFFSIDES
95	Periodontitis			OFFSIDES
96	Peripheral Nervous System Diseases		1336008	CTD
97	Peritoneal Infection			OFFSIDES
98	Pharyngolaryngeal Pain			OFFSIDES
99	Pleural fistula			OFFSIDES
100	Pneumothorax			OFFSIDES
101	Polycystic Ovary Syndrome		26545973	CTD
102	Prostatic Neoplasms		23575993	CTD
103	Retinal Vein Occlusion			OFFSIDES
104	Rhabdomyolysis			OFFSIDES
105	Risus sardonicus			OFFSIDES
106	Seizures		View details 2892286 19798568 19800361 20592767 21620807	CTD
107	Skin test positive			OFFSIDES
108	Status Epilepticus		15752349	CTD
109	Stomach Diseases		3613839	CTD
110	Ureteral Calculi		24360074	CTD
111	Urinary Bladder Diseases		2773078 7548731	CTD
112	Ventricle rupture			OFFSIDES
113	jaundice		8377599	CTD

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