MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Thymidine

(IQFYYKKMVGJFEH-XLPZGREQSA-N)

Structure

SMILES: OC[C@H]1O[C@H](C[C@@H]1O)n1cc(C)c(=O)[nH]c1=O
Type(s): Experimental; Investigational
Molecular Formula:: C10H14N2O5
Molecular Weight:: 242.229
Log P:: -1.5143
Hydrogen Bond Acceptor:: 6
Hydrogen Bond Donor:: 3
TPSA:: 104.55
CAS Number(s):: 50-89-5; 3424-98-4; 157049-39-3; 157049-40-6

Synonym(s)

Thymidine

2'-Deoxythymidine

Deoxythymidine

2' Deoxythymidine

External Link(s)

MeSH	D013936
PubChem Compound	5789
BindingDB	1
ChEBI	17748
CHEMBL	CHEMBL52609
DrugBank	DB04485
IUPHAR/BPS Guide to PHARMACOLOGY	4718
KEGG	cpd:C00214
Therapeutic Target Database	D01GLG D0X4JL
ZINC	25672

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Abdominal Pain		OFFSIDES SIDER
2	Abdominal discomfort		OFFSIDES SIDER
3	Abdominal rebound tenderness		OFFSIDES
4	Abdominal tenderness		OFFSIDES
5	Acidosis		OFFSIDES
6	Acute Coronary Syndrome		OFFSIDES
7	Acute kidney injury	1838364	CTD
8	Acute respiratory failure		OFFSIDES
9	Alanine Aminotransferase Increased		OFFSIDES SIDER
10	Alpha hydroxybutyrate dehydrogenase increased		OFFSIDES
11	Amylase increased		SIDER
12	Anorexia		OFFSIDES
13	Anuria		OFFSIDES
14	Anxiety		OFFSIDES
15	Apathy		OFFSIDES
16	Appendicitis		OFFSIDES
17	Arteriosclerosis		OFFSIDES
18	Arthralgia		SIDER
19	Aspartate Aminotransferase Increased		SIDER
20	Asterixis		OFFSIDES
21	Asthenia		OFFSIDES SIDER
22	Asthma		OFFSIDES
23	Atrial hypertrophy		OFFSIDES
24	Atrial tachycardia		OFFSIDES
25	Axonal neuropathy		OFFSIDES
26	Back Pain		SIDER
27	Band neutrophil percentage increased		OFFSIDES
28	Base excess increased		OFFSIDES
29	Bilirubin conjugated increased		OFFSIDES
30	Blood Glucose		OFFSIDES
31	Blood amylase increased		SIDER
32	Blood bilirubin unconjugated increased		OFFSIDES
33	Blood creatine phosphokinase		OFFSIDES
34	Blood creatine phosphokinase MB		OFFSIDES
35	Blood creatine phosphokinase MB abnormal		OFFSIDES
36	Blood creatine phosphokinase MB increased		OFFSIDES
37	Blood creatine phosphokinase abnormal		OFFSIDES
38	Blood creatine phosphokinase increased		OFFSIDES SIDER
39	Blood creatinine increased		OFFSIDES
40	Blood gases abnormal		OFFSIDES
41	Blood lactate dehydrogenase increased		OFFSIDES
42	Blood pH decreased		OFFSIDES
43	Blood potassium decreased		OFFSIDES
44	Blood potassium increased		OFFSIDES
45	Blood pressure fluctuation		OFFSIDES
46	Blood urea increased		OFFSIDES
47	Blood uric acid		OFFSIDES
48	Blood urine present		OFFSIDES
49	Brain Diseases	9816193	CTD
50	Cardiac enzymes increased		OFFSIDES
51	Chest Pain		SIDER
52	Chest discomfort		SIDER
53	Chest wall pain		SIDER
54	Choking sensation		OFFSIDES
55	Cholangiolitis		OFFSIDES
56	Chromaturia		OFFSIDES
57	Chronic left ventricular failure		OFFSIDES
58	Claustrophobia		OFFSIDES
59	Colorectal Neoplasms	6491697	CTD
60	Craniotomy		OFFSIDES
61	Creatine Phosphokinase Increased		SIDER
62	Demyelination		OFFSIDES
63	Dermatitis		SIDER
64	Discomfort		SIDER
65	Disease Progression		OFFSIDES SIDER
66	Disseminated Intravascular Coagulation		OFFSIDES
67	Dizziness		SIDER
68	Drowsiness		OFFSIDES
69	Drug exposure during pregnancy		OFFSIDES
70	Dysgeusia		SIDER
71	Dyspepsia		SIDER
72	Electromyogram abnormal		OFFSIDES
73	Eosinophilic myocarditis		OFFSIDES
74	Erosive gastritis		OFFSIDES
75	Escherichia sepsis		OFFSIDES
76	Exanthema	6607976	CTD
77	Fatigue		OFFSIDES SIDER
78	Feeling abnormal		OFFSIDES SIDER
79	Feeling of body temperature change		OFFSIDES
80	Fibromyalgia		SIDER
81	Flank Pain		SIDER
82	Food aversion		OFFSIDES
83	Formication		OFFSIDES
84	Full blood count increased		OFFSIDES
85	Gastritis		SIDER
86	Gastrointestinal Pain		SIDER
87	Headache		SIDER
88	Hepatitis B DNA increased		OFFSIDES
89	Hepatitis B surface antigen positive		OFFSIDES
90	Hepatitis B		OFFSIDES SIDER
91	Hepatitis		SIDER
92	Hepatomegaly		SIDER
93	Hyperreflexia		OFFSIDES
94	Hyperventilation		OFFSIDES
95	Influenza-like symptoms		SIDER
96	Influenza		SIDER
97	Infusion site mobility decreased		OFFSIDES
98	Leukopenia	6491697 6607976	CTD
99	Limb discomfort		OFFSIDES
100	Lipase increased		SIDER
101	Liver Neoplasms, Experimental	6145526	CTD
102	Lumbar radiculopathy		OFFSIDES
103	Lymphocytic infiltration		OFFSIDES
104	Malaise		SIDER
105	Malnutrition		SIDER
106	Marasmus		OFFSIDES
107	Mechanical ventilation		OFFSIDES
108	Metabolic acidosis		OFFSIDES
109	Muscle Fatigue		OFFSIDES
110	Muscle Weakness		OFFSIDES
111	Muscle necrosis		OFFSIDES
112	Muscle strain		OFFSIDES
113	Musculoskeletal Pain		OFFSIDES SIDER
114	Musculoskeletal chest pain		SIDER
115	Musculoskeletal discomfort		OFFSIDES SIDER
116	Musculoskeletal stiffness		OFFSIDES SIDER
117	Myalgia		SIDER
118	Myoglobin blood increased		OFFSIDES
119	Myopathy		SIDER
120	Myositis		SIDER
121	Nasopharyngitis		SIDER
122	Nausea		OFFSIDES SIDER
123	Neck Pain		SIDER
124	Necrosis	4049281	CTD
125	Nephrolithiasis		OFFSIDES
126	Neural Tube Defects	4049281	CTD
127	Neuralgia		OFFSIDES
128	Neurologic Manifestations	6491697	CTD
129	Neutropenia		SIDER
130	Non-cardiac chest pain		SIDER
131	Ocular icterus		OFFSIDES
132	Oliguria		OFFSIDES
133	Oropharyngeal pain		OFFSIDES
134	PCO2 decreased		OFFSIDES
135	Pain of skin		OFFSIDES
136	Pain		OFFSIDES SIDER
137	Pallor		OFFSIDES
138	Peripheral arterial occlusive disease		OFFSIDES
139	Pharyngitis		SIDER
140	Pharyngolaryngeal Pain		SIDER
141	Poikilocytosis		OFFSIDES
142	Polymyositis		OFFSIDES
143	Polyneuropathy		OFFSIDES
144	Poor quality sleep		OFFSIDES
145	Post procedural pain		SIDER
146	Prenatal Exposure Delayed Effects	4049281	CTD
147	Productive Cough		SIDER
148	Protein total decreased		OFFSIDES
149	Pruritus		SIDER
150	Pulmonary Hypertension		OFFSIDES
151	Rales		OFFSIDES
152	Renal Insufficiency	9164227	CTD
153	Respiratory Failure		OFFSIDES
154	Rhabdomyolysis		OFFSIDES SIDER
155	Rheumatoid factor increased		OFFSIDES
156	Rhinorrhea		OFFSIDES
157	Right upper quadrant pain		SIDER
158	Sciatica		SIDER
159	Sepsis		SIDER
160	Sinus headache		SIDER
161	Stiffness		SIDER
162	Stomatitis	6607976	CTD
163	Stress ulcer		OFFSIDES
164	Tension Headache		SIDER
165	Thrombocytopenia	6607976	CTD SIDER
166	Total bile acids increased		OFFSIDES
167	Transaminases abnormal		OFFSIDES
168	Troponin I increased		OFFSIDES
169	Troponin increased		OFFSIDES
170	Ultrasound liver abnormal		OFFSIDES
171	Urine bilirubin increased		OFFSIDES
172	Urine ketone body present		OFFSIDES
173	Vibration test abnormal		OFFSIDES
174	Vital functions abnormal		OFFSIDES
175	Vomiting		SIDER
176	Wound Complication		OFFSIDES
177	effusion		OFFSIDES
178	muscle injury		OFFSIDES
179	nervous system disorder		SIDER

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