MetaADEDB 2.0 @ LMMD
Flutamide
(MKXKFYHWDHIYRV-UHFFFAOYSA-N)
Structure
SMILES
O=C(C(C)C)Nc1ccc(c(c1)C(F)(F)F)[N+](=O)[O-]
Type(s)
Approved; Investigational
ATC code(s)
L02BB01
Molecular Formula:
C11H11F3N2O3
Molecular Weight:
276.212
Log P:
3.8043
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
1
TPSA:
74.92
CAS Number(s):
13311-84-7; 37209-54-4
Synonym(s)
1.
Flutamide
2.
Niftolid
3.
Apimid
4.
Apo-Flutamide
5.
Chimax
6.
Cytamid
7.
Drogenil
8.
Euflex
9.
Eulexin
10.
Eulexine
11.
Fluken
12.
Flulem
13.
Flumid
14.
Fluta 1A Pharma
15.
Fluta-GRY
16.
Fluta-cell
17.
Flutamin
18.
Flutandrona
19.
Flutaplex
20.
Flutexin
21.
Fugerel
22.
Grisetin
23.
Niftolide
24.
Novo-Flutamide
25.
Oncosal
26.
PMS-Flutamide
27.
Prostacur
28.
Prostica
29.
Prostogenat
30.
SCH-13521
31.
Testotard
32.
Apo Flutamide
33.
ApoFlutamide
34.
Fluta GRY
35.
Fluta cell
36.
FlutaGRY
37.
Flutacell
38.
Novo Flutamide
39.
NovoFlutamide
40.
PMS Flutamide
41.
SCH 13521
42.
SCH13521
External Link(s)
MeSHD005485
PubChem Compound3397
BindingDB50131270
ChEBI5132
CHEMBLCHEMBL806
DrugBankDB00499
DrugCentral1223
IUPHAR/BPS Guide to PHARMACOLOGY6943
KEGGcpd:C07653
dr:D00586
Therapeutic Target DatabaseD0Y0SW
ZINC3812944
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1MeningitisFAERS: 3US FAERS
2PneumoniaFAERS: 3US FAERS
3Post procedural complicationFAERS: 3US FAERS
4Adverse eventFAERS: 2US FAERS
5Alanine Aminotransferase IncreasedFAERS: 2OFFSIDES
US FAERS
6AstheniaFAERS: 2OFFSIDES
SIDER
US FAERS
7Bronchoalveolar lavage abnormalFAERS: 2OFFSIDES
US FAERS
8HypoxiaFAERS: 2US FAERS
9AbasiaFAERS: 1OFFSIDES
US FAERS
10Abdominal PainFAERS: 1OFFSIDES
US FAERS
11Activities of daily living impairedFAERS: 1US FAERS
12AnxietyFAERS: 1OFFSIDES
SIDER
US FAERS
13ArthralgiaFAERS: 1US FAERS
14Aspartate Aminotransferase IncreasedFAERS: 1SIDER
US FAERS
15Blood alkaline phosphatase increasedFAERS: 1OFFSIDES
US FAERS
16Blood lactate dehydrogenase increasedFAERS: 1OFFSIDES
US FAERS
17Bone painFAERS: 1OFFSIDES
US FAERS
18Chest PainFAERS: 1US FAERS
19Chest discomfortFAERS: 1US FAERS
20CholestasisFAERS: 117409513CTD
US FAERS
21CyanosisFAERS: 1US FAERS
22DysgraphiaFAERS: 1US FAERS
23Escherichia urinary tract infectionFAERS: 1US FAERS
24FatigueFAERS: 1SIDER
US FAERS
25Gastric ulcerFAERS: 1OFFSIDES
US FAERS
26General physical health deteriorationFAERS: 1OFFSIDES
US FAERS
27HeadacheFAERS: 1SIDER
US FAERS
28Hepatic necrosisFAERS: 1SIDER
US FAERS
29Hepatitis EFAERS: 1US FAERS
30HepatitisFAERS: 1

View details

2311846
8734324
9267134
10386060
10396113
16307333
 		CTD
SIDER
US FAERS
31HepatomegalyFAERS: 128108177CTD
US FAERS
32HepatotoxicityFAERS: 1OFFSIDES
US FAERS
33HypotensionFAERS: 1US FAERS
34Impaired driving abilityFAERS: 1US FAERS
35IntussusceptionFAERS: 1US FAERS
36MalaiseFAERS: 1SIDER
US FAERS
37Malignant neoplasm progressionFAERS: 1US FAERS
38MetastasisFAERS: 1SIDER
US FAERS
39MyalgiaFAERS: 1US FAERS
40NauseaFAERS: 1OFFSIDES
SIDER
US FAERS
41PhlebitisFAERS: 1US FAERS
42ProlactinomaFAERS: 1US FAERS
43PyelonephritisFAERS: 1US FAERS
44Respiratory FailureFAERS: 1US FAERS
45RetinitisFAERS: 1US FAERS
46SchizophreniaFAERS: 1US FAERS
47SomnolenceFAERS: 1SIDER
US FAERS
48Systemic lupus erythematosus rashFAERS: 1US FAERS
49VitiligoFAERS: 1US FAERS
50VomitingFAERS: 1SIDER
US FAERS
51Acid refluxOFFSIDES
52Acute kidney injury12180480CTD
53Acute respiratory failureOFFSIDES
54Acute sinusitisOFFSIDES
55Adenocarcinoma12820454
15154626		CTD
OFFSIDES
56Anemia10233450
12820454		CTD
57AnhidrosisOFFSIDES
58Ankle FractureOFFSIDES
59AnorexiaOFFSIDES
SIDER
60Aortic AneurysmOFFSIDES
61ApathyOFFSIDES
62ArteriosclerosisOFFSIDES
63ArthritisOFFSIDES
64Ascites2911917CTD
65AsterixisOFFSIDES
66AtaxiaOFFSIDES
67AtelectasisOFFSIDES
68Atrial FlutterOFFSIDES
69Basal ganglion degenerationOFFSIDES
70BedriddenOFFSIDES
71Benign Prostatic HyperplasiaOFFSIDES
72Bladder painSIDER
73BlepharitisOFFSIDES
74Blood GlucoseOFFSIDES
75Blood albumin increasedOFFSIDES
76Blood chloride increasedOFFSIDES
77Blood creatinine increasedOFFSIDES
78Blood iron increasedOFFSIDES
79Blood parathyroid hormone increasedOFFSIDES
80Blood phosphorus increasedOFFSIDES
81Blood urea increasedSIDER
82Blood uric acidOFFSIDES
83Bone lesionOFFSIDES
84Bone scan abnormalOFFSIDES
85Brain stem thrombosisOFFSIDES
86Breast Neoplasms, Male15154626CTD
87Breast tendernessSIDER
88BronchiectasisOFFSIDES
89BronchitisOFFSIDES
90BronchopneumoniaOFFSIDES
91Bullous eruptionSIDER
92Carcinoma8708714CTD
SIDER
93Cardiovascular Diseases8708714CTD
94Carotid bruitOFFSIDES
95Cataract operationOFFSIDES
96CataractOFFSIDES
97Cerebral artery occlusionOFFSIDES
98Chemical and Drug Induced Liver Injury

View details

1835038
2719431
2911917
8359091
8943975
9324896
9742783
9759603
9927799
10215102
10902281
11563686
14971714
14997310
16137480
19442681
21735453
22166485
22258563
22331495
22843567
23397584
24085192
24136188
24747151
25371773
26921665
27485346
28069987
28437613
28762043
 		CTD
99CholangiolitisOFFSIDES
100CholecystitisOFFSIDES
101ChromaturiaSIDER
102Chronic sinusitisOFFSIDES
103Clostridium difficile colitisOFFSIDES
104Colitis, Ischemic9854217CTD
105ColitisOFFSIDES
106Colon adenomaOFFSIDES
107Congenital tricuspid valve incompetenceOFFSIDES
108ConstipationSIDER
109Cor pulmonaleOFFSIDES
110Cryptorchidism18340380CTD
111Cyst removalOFFSIDES
112CystitisSIDER
113CystOFFSIDES
114DeafnessOFFSIDES
115Dental FistulaOFFSIDES
116Dental abscessOFFSIDES
117Dental cariesOFFSIDES
118DermatitisSIDER
119DiabetesOFFSIDES
120Diabetes MellitusSIDER
121Diabetes mellitus exacerbatedSIDER
122DiarrheaOFFSIDES
123DiscomfortSIDER
124Disturbance in sexual arousalSIDER
125DiverticulosisOFFSIDES
126DiverticulumOFFSIDES
127DizzinessSIDER
128DrowsinessSIDER
129Drug toxicityOFFSIDES
130Drug withdrawal headacheOFFSIDES
131DyspepsiaOFFSIDES
132DysphemiaOFFSIDES
133EcchymosisSIDER
134EczemaOFFSIDES
135Edema7837136
24992288		CTD
136Embolic strokeOFFSIDES
137Endodontic procedureOFFSIDES
138Erectile dysfunction3358677
10646878
10737536		CTD
OFFSIDES
SIDER
139ErythemaSIDER
140Essential HypertensionOFFSIDES
141ExophthalmosOFFSIDES
142Extremity necrosisOFFSIDES
143Eye painOFFSIDES
144Feeling abnormalOFFSIDES
SIDER
145Feeling of body temperature changeOFFSIDES
146FlatulenceOFFSIDES
147Focal glomerulosclerosisOFFSIDES
148FormicationOFFSIDES
149GangreneOFFSIDES
150Gene MutationOFFSIDES
151Genital Diseases, Male12446607CTD
152Glossopharyngeal nerve paralysisOFFSIDES
153GoiterOFFSIDES
154Graft infectionOFFSIDES
155GranulomaOFFSIDES
156Gynecomastia15715105CTD
157Hair Diseases12962443CTD
158Heart Diseases22166485CTD
159Hepatic Encephalopathy

View details

2911917
8014445
9091557
12962443
15017238
 		CTD
SIDER
160Hepatic Insufficiency7771407CTD
161Hepatitis B positiveOFFSIDES
162Hepatitis, Animal18559427CTD
163Hirsutism7837136
10459914		CTD
164Hyperandrogenism15356085CTD
165HyperparathyroidismOFFSIDES
166Hyperplasia17311803
21525395		CTD
167Hypertensive angiopathyOFFSIDES
168Hypertensive heart diseaseOFFSIDES
169Hypospadias18340380CTD
170Incorrect route of drug administrationOFFSIDES
171InfectionOFFSIDES
172Infusion site mobility decreasedOFFSIDES
173Injection site irritationSIDER
174Intentional drug misuseOFFSIDES
175Intestinal infarctionOFFSIDES
176LeukopeniaSIDER
177Limb injuryOFFSIDES
178Liver Failure, Acute

View details

8014445
9102495
10215102
10459914
10985104
 		CTD
179Liver Failure

View details

2365984
9324896
10386060
14997310
 		CTD
180Liver diseases

View details

10431581
10500955
11411099
13129633
 		CTD
181Mastication disorderOFFSIDES
182Memory Disorders24902786CTD
183Mental disorders3777267CTD
184Metabolic acidosisOFFSIDES
185Metastatic CarcinomaSIDER
186Metastatic NeoplasmSIDER
187Metastatic painOFFSIDES
188Muscle WeaknessOFFSIDES
189Musculoskeletal discomfortOFFSIDES
190Musculoskeletal stiffnessOFFSIDES
191MyelodysplasiaOFFSIDES
192Necrolysis epidermalSIDER
193Nephrotic SyndromeOFFSIDES
194NervousnessSIDER
195Neurosensory hypoacusisOFFSIDES
196NoduleOFFSIDES
SIDER
197Occult blood positiveOFFSIDES
198Ocular vascular disorderOFFSIDES
199Oligospermia11856573CTD
200Oral dischargeOFFSIDES
201OsteopeniaOFFSIDES
202PainOFFSIDES
203PancreatitisOFFSIDES
204Penile size reducedOFFSIDES
205Peripheral arterial occlusive diseaseOFFSIDES
206Physical disabilityOFFSIDES
207Platelet count abnormalOFFSIDES
208Poisoning28728110CTD
209Polycystic Ovary Syndrome15356085CTD
210Postoperative wound complicationOFFSIDES
211Prenatal Exposure Delayed Effects27639664CTD
212ProctitisOFFSIDES
SIDER
213Prostate cancer recurrentOFFSIDES
214Prostatic Hyperplasia10752671CTD
215Prostatic Neoplasms

View details

2201041
2365984
2911917
3169114
3777267
7505229
8014445
8359091
8708714
8826789
8943975
9091557
9267134
9324896
9759603
10215102
10386060
10431581
10500955
10752671
11085345
11411099
11563686
12180480
12820454
14997310
15154626
16307333
19442681
21846139
22076107
28757136
 		CTD
216Protein total decreasedOFFSIDES
217PruritusSIDER
218Pulmonary EmbolismSIDER
219Pulmonary congestionOFFSIDES
220Pulmonary function test decreasedOFFSIDES
221Red blood cell schistocytes presentOFFSIDES
222Renal Insufficiency22166485CTD
223Renal abscessOFFSIDES
224Renal cystOFFSIDES
225Reperfusion Injury17973111CTD
226Retinal vascular occlusionOFFSIDES
227Retroperitoneal lymphadenopathyOFFSIDES
228Seizures12752460CTD
229Septic ShockOFFSIDES
230SinusitisOFFSIDES
231Skin ErosionOFFSIDES
232Spinal column stenosisOFFSIDES
233StressOFFSIDES
234Subcutaneous AbscessOFFSIDES
235Supraventricular tachycardiaOFFSIDES
236SympathicotoniaOFFSIDES
237TensionSIDER
238Testicular Diseases17679765
26485406		CTD
239TetanyOFFSIDES
240Thoracic vertebral fractureOFFSIDES
241Thrombin-antithrombin III complex increasedOFFSIDES
242ThrombocytopeniaSIDER
243Thromboembolism8708714CTD
244ThyroidectomyOFFSIDES
245Tooth LossOFFSIDES
246Toxic Epidermal NecrolysisSIDER
247Transaminases increasedSIDER
248Traumatic liver injurySIDER
249Tumor Lysis Syndrome15017238CTD
250UlcerSIDER
251Urge IncontinenceOFFSIDES
252VertebroplastyOFFSIDES
253Wound necrosisOFFSIDES
254jaundice2911917
12962443		CTD
SIDER
255kyphosisOFFSIDES
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