MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Nitrendipine

(PVHUJELLJLJGLN-UHFFFAOYSA-N)

Structure

SMILES: CCOC(=O)C1=C(C)NC(=C(C1c1cccc(c1)[N+](=O)[O-])C(=O)OC)C
Type(s): Approved; Investigational
ATC code(s): C08CA08; C09BB06
Molecular Formula:: C18H20N2O6
Molecular Weight:: 360.361
Log P:: 3.4177
Hydrogen Bond Acceptor:: 5
Hydrogen Bond Donor:: 1
TPSA:: 110.45
CAS Number(s):: 39562-70-4; 80873-62-7; 86052-02-0

Synonym(s)

Nitrendipine

Balminil

Bay e 5009

Bayotensin

Baypresol

Baypress

Gericin

Jutapress

Nidrel

10.

Niprina

11.

Nitre AbZ

12.

Nitre-Puren

13.

Nitregamma

14.

Nitren 1A Pharma

15.

Nitren Lich

16.

Nitren acis

17.

Nitrend KSK

18.

Nitrendepat

19.

Nitrendi Biochemie

20.

Nitrendidoc

21.

Nitrendimerck

22.

Nitrendipin AL

23.

Nitrendipin Apogepha

24.

Nitrendipin Atid

25.

Nitrendipin Basics

26.

Nitrendipin Heumann

27.

Nitrendipin Jenapharm

28.

Nitrendipin Lindo

29.

Nitrendipin Stada

30.

Nitrendipin beta

31.

Nitrendipin-ratiopharm

32.

Nitrendipino Bayvit

33.

Nitrendipino Ratiopharm

34.

Nitrensal

35.

Nitrepress

36.

Tensogradal

37.

Trendinol

38.

Vastensium

39.

nitrendipin von ct

40.

nitrendipin-corax

41.

Nitre Puren

42.

NitrePuren

43.

Nitrendipin ratiopharm

44.

Nitrendipinratiopharm

45.

nitrendipin corax

46.

nitrendipincorax

External Link(s)

MeSH	D009568
PubChem Compound	4507
BindingDB	50237611 50012016
ChEBI	7582
CHEMBL	CHEMBL475534 CHEMBL3195219
DrugBank	DB01054
DrugCentral	1947
IUPHAR/BPS Guide to PHARMACOLOGY	2334
KEGG	cpd:C07713 dr:D00629
Therapeutic Target Database	D0A1DH

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Abdominal Infection		OFFSIDES
2	Acute myocardial infarction		OFFSIDES
3	Acute prerenal failure		OFFSIDES
4	Adenoma		OFFSIDES
5	Adverse event		OFFSIDES
6	Albuminuria	1639466 8282322 8743521	CTD
7	Amblyopia		OFFSIDES
8	Arthropathy		OFFSIDES
9	Atherosclerosis	3300663	CTD
10	Atrial tachycardia		OFFSIDES
11	Benign Prostatic Hyperplasia		OFFSIDES
12	Blood aldosterone increased		OFFSIDES
13	Blood count abnormal		OFFSIDES
14	Blood creatine increased		OFFSIDES
15	Blood creatine phosphokinase increased		OFFSIDES
16	Blood creatinine increased		OFFSIDES
17	Blood parathyroid hormone		OFFSIDES
18	Blood pressure inadequately controlled		OFFSIDES
19	Blood sodium increased		OFFSIDES
20	Blood sodium		OFFSIDES
21	Blood thyroid stimulating hormone increased		OFFSIDES
22	Blood uric acid		OFFSIDES
23	Calciphylaxis		OFFSIDES
24	Candidiasis of vagina		OFFSIDES
25	Cardiomegaly	6085384	CTD
26	Catalepsy	11143713	CTD
27	Cataract operation		OFFSIDES
28	Cataract		OFFSIDES
29	Catheter site pain		OFFSIDES
30	Catheter site swelling		OFFSIDES
31	Cerebellar infarction		OFFSIDES
32	Cerebral atrophy		OFFSIDES
33	Choking sensation		OFFSIDES
34	Cholecystitis		OFFSIDES
35	Cytolytic hepatitis		OFFSIDES
36	Dehydration		OFFSIDES
37	Diabetic Nephropathy		OFFSIDES
38	Diplopia		OFFSIDES
39	Diverticulum		OFFSIDES
40	Drowsiness		OFFSIDES
41	Drug administration error		OFFSIDES
42	Duodenal Ulcer		OFFSIDES
43	Edema	2642658 2920503	CTD
44	Electromechanical dissociation		OFFSIDES
45	Enterococcal sepsis		OFFSIDES
46	Epistaxis		OFFSIDES
47	Erosive gastritis		OFFSIDES
48	Erythema Multiforme		OFFSIDES
49	Escherichia urinary tract infection		OFFSIDES
50	Familial Mediterranean Fever		OFFSIDES
51	Fatty Liver		OFFSIDES
52	Flushing	2920503	CTD
53	Formication		OFFSIDES
54	Gastric ulcer		OFFSIDES
55	Gastrointestinal infection		OFFSIDES
56	Gastrointestinal mucosal disorder		OFFSIDES
57	General physical health deterioration		OFFSIDES
58	Genital erosion		OFFSIDES
59	Helicobacter pylori identification test positive		OFFSIDES
60	Hepatic artery thrombosis		OFFSIDES
61	Hyperaldosteronism		OFFSIDES
62	Hypotension	8345498	CTD
63	Hypoxia	2327189	CTD
64	Implant site infection		OFFSIDES
65	Incorrect dose administered		OFFSIDES
66	Infection in an immunocompromised host		OFFSIDES
67	Intestinal infarction		OFFSIDES
68	Ischemia	6085384	CTD
69	Leukoencephalopathy		OFFSIDES
70	Lip erosion		OFFSIDES
71	Lupus Erythematosus, Cutaneous	12695145	CTD
72	Lymphocyte stimulation test positive		OFFSIDES
73	Lymphocyte transformation test positive		OFFSIDES
74	Magnesium Deficiency		OFFSIDES
75	Muscle necrosis		OFFSIDES
76	Myelodysplasia		OFFSIDES
77	Nasal mucosal disorder		OFFSIDES
78	Nephrosclerosis	1639466	CTD
79	Oliguria		OFFSIDES
80	Orchitis		OFFSIDES
81	Overdose		OFFSIDES
82	Pain of skin		OFFSIDES
83	Peripheral embolism		OFFSIDES
84	Peritonitis		OFFSIDES
85	Pneumocystis jiroveci pneumonia		OFFSIDES
86	Polyuria		OFFSIDES
87	Post procedural urine leak		OFFSIDES
88	Productive Cough		OFFSIDES
89	Psychomotor skills impaired		OFFSIDES
90	Pulmonary congestion		OFFSIDES
91	Renal Artery Stenosis		OFFSIDES
92	Renal aneurysm		OFFSIDES
93	Renal artery occlusion		OFFSIDES
94	Retinal vascular occlusion		OFFSIDES
95	Retinitis		OFFSIDES
96	Rhabdomyolysis		OFFSIDES
97	Seizures	1963805	CTD
98	Skin lesion		OFFSIDES
99	Soft Tissue Infection		OFFSIDES
100	Soft tissue necrosis		OFFSIDES
101	Staring		OFFSIDES
102	Stevens-Johnson Syndrome		OFFSIDES
103	Substance Withdrawal Syndrome	1557510 10702963	CTD
104	Tachycardia	1691398 1691399 2642658	CTD
105	Thrombophlebitis		OFFSIDES
106	Thyroidectomy		OFFSIDES
107	Urinary tract infection enterococcal		OFFSIDES
108	Vascular Diseases	1646895	CTD
109	Vascular calcification	6085384	CTD
110	Ventricular Dysfunction, Left	9250456	CTD
111	Visual disturbance		OFFSIDES
112	kyphosis		OFFSIDES

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