MetaADEDB 2.0 @ LMMD
Desonide
(WBGKWQHBNHJJPZ-LECWWXJVSA-N)
Structure
SMILES
OCC(=O)[C@@]12OC(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@H]2[C@H]1CCC1=CC(=O)C=C[C@]21C)(C)C
Type(s)
Approved; Investigational
ATC code(s)
D07AB08; D07BB02; S01BA11
Molecular Formula:
C24H32O6
Molecular Weight:
416.507
Log P:
2.3267
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
93.06
CAS Number(s):
638-94-8
Synonym(s)
1.
Desonide
2.
Prednacinolone
3.
Desocort
4.
Desone
5.
Desowen
6.
Locapred
7.
Locatop
8.
Tridesilon
9.
Tridésonit
External Link(s)
MeSHD003898
PubChem Compound5311066
ChEBI204734
CHEMBLCHEMBL1201109
DrugBankDB01260
DrugCentral3135
IUPHAR/BPS Guide to PHARMACOLOGY7066
KEGGdr:D03696
Therapeutic Target DatabaseD02JNM
ZINC4212851
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 18OFFSIDES
US FAERS
2Application site painFAERS: 11SIDER
US FAERS
3Application site erythemaFAERS: 8SIDER
US FAERS
4ErythemaFAERS: 6OFFSIDES
SIDER
US FAERS
5Expired product administeredFAERS: 6US FAERS
6Product physical consistency issueFAERS: 6US FAERS
7Product quality issueFAERS: 4US FAERS
8Product use in unapproved indicationFAERS: 4US FAERS
9Application site burnFAERS: 3OFFSIDES
SIDER
US FAERS
10Application site irritationFAERS: 3SIDER
US FAERS
11Dry skinFAERS: 3OFFSIDES
US FAERS
12EczemaFAERS: 3OFFSIDES
US FAERS
13HypersensitivityFAERS: 3US FAERS
14Product use issueFAERS: 3US FAERS
15PruritusFAERS: 3
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
16Skin irritationFAERS: 3US FAERS
17UrticariaFAERS: 3US FAERS
18Abdominal discomfortFAERS: 2OFFSIDES
US FAERS
19Application site exfoliationFAERS: 2US FAERS
20Application site reactionFAERS: 2SIDER
US FAERS
21Burning sensationFAERS: 2US FAERS
22CataractFAERS: 2OFFSIDES
US FAERS
23DermatitisFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
24Eye irritationFAERS: 2US FAERS
25Eye painFAERS: 2OFFSIDES
US FAERS
26HeadacheFAERS: 2SIDER
US FAERS
27Skin tightnessFAERS: 2US FAERS
28Accidental exposure to productFAERS: 1US FAERS
29AlopeciaFAERS: 1OFFSIDES
US FAERS
30Ankle FractureFAERS: 1US FAERS
31Application site atrophyFAERS: 1SIDER
US FAERS
32Application site papulesFAERS: 1US FAERS
33Application site pruritusFAERS: 1SIDER
US FAERS
34Application site rashFAERS: 1SIDER
US FAERS
35Drug dose omissionFAERS: 1US FAERS
36Drug effective for unapproved indicationFAERS: 1US FAERS
37Drug ineffective for unapproved indicationFAERS: 1US FAERS
38DysphemiaFAERS: 1US FAERS
39FlatulenceFAERS: 1US FAERS
40Inappropriate schedule of drug administrationFAERS: 1US FAERS
41Incorrect dose administeredFAERS: 1US FAERS
42Incorrect product administration durationFAERS: 1US FAERS
43Incorrect route of drug administrationFAERS: 1US FAERS
44InfectionFAERS: 1SIDER
US FAERS
45Intentional product misuseFAERS: 1US FAERS
46Intentional product use issueFAERS: 1US FAERS
47Intercepted medication errorFAERS: 1US FAERS
48MalaiseFAERS: 1US FAERS
49Medication ErrorFAERS: 1US FAERS
50NauseaFAERS: 1OFFSIDES
US FAERS
51No adverse eventFAERS: 1US FAERS
52PainFAERS: 1OFFSIDES
SIDER
US FAERS
53PallorFAERS: 1US FAERS
54Poor quality product administeredFAERS: 1US FAERS
55Product substitution issueFAERS: 1US FAERS
56PsoriasisFAERS: 16754511CTD
OFFSIDES
US FAERS
57Skin discomfortFAERS: 1US FAERS
58Skin test positiveFAERS: 1US FAERS
59Steroid withdrawal syndromeFAERS: 1US FAERS
60Therapeutic response unexpectedFAERS: 1US FAERS
61Unevaluable eventFAERS: 1US FAERS
62VomitingFAERS: 1US FAERS
63Wrong technique in product usage processFAERS: 1US FAERS
64AbasiaOFFSIDES
65Abdominal AbscessOFFSIDES
66Abdominal PainOFFSIDES
67Abnormal visionOFFSIDES
68Acid refluxOFFSIDES
69Actinic keratosisOFFSIDES
70Acute respiratory failureOFFSIDES
71AdenocarcinomaOFFSIDES
72Adenomatous Polyposis ColiOFFSIDES
73AgoraphobiaOFFSIDES
74AmnesiaOFFSIDES
75Anal FissureOFFSIDES
76AnhedoniaOFFSIDES
77AnorexiaOFFSIDES
78AnxietyOFFSIDES
79AppendectomyOFFSIDES
80ArteriosclerosisOFFSIDES
81ArthritisOFFSIDES
82AstheniaOFFSIDES
83AsthmaOFFSIDES
SIDER
84AtelectasisOFFSIDES
85AtherosclerosisOFFSIDES
86Atrial tachycardiaOFFSIDES
87AuraOFFSIDES
88Bacterial disease carrierOFFSIDES
89Band neutrophil count increasedOFFSIDES
90Basal cell carcinomaOFFSIDES
91Blood albumin decreasedOFFSIDES
92Blood cholesterolOFFSIDES
93Blurred visionOFFSIDES
94Bone lesionOFFSIDES
95Bone painOFFSIDES
96BradycardiaOFFSIDES
97CandiduriaOFFSIDES
98Cataract operationOFFSIDES
99CellulitisOFFSIDES
100Chest PainOFFSIDES
101Choking sensationOFFSIDES
102Choroidal DetachmentOFFSIDES
103Chronic Obstructive Airway DiseaseOFFSIDES
104Chronic ulcerative colitisOFFSIDES
105Clostridium difficile colitisOFFSIDES
106ColitisOFFSIDES
107Colon adenomaOFFSIDES
108Completed SuicideOFFSIDES
109Conjunctival depositOFFSIDES
110Contact DermatitisOFFSIDES
111Corneal dystrophyOFFSIDES
112CryotherapyOFFSIDES
113Delayed sleep phaseOFFSIDES
114DemyelinationOFFSIDES
115Dermatitis acneiformSIDER
116Dermatitis, Allergic Contact2530056CTD
117DiabetesOFFSIDES
118DiarrheaOFFSIDES
119DiverticulitisOFFSIDES
120DiverticulumOFFSIDES
121DizzinessOFFSIDES
122Drug exposure during pregnancyOFFSIDES
123Drug withdrawal headacheOFFSIDES
124DysgeusiaOFFSIDES
125DysmenorrheaOFFSIDES
126DysphoniaOFFSIDES
127Dysthymic DisorderOFFSIDES
128DysuriaOFFSIDES
129Economic problemOFFSIDES
130Emotional disorderOFFSIDES
131Enamel anomalyOFFSIDES
132Endodontic procedureOFFSIDES
133Erythrodermic psoriasisOFFSIDES
134Essential HypertensionOFFSIDES
135Eye laser surgeryOFFSIDES
136FatigueOFFSIDES
137FibromyalgiaOFFSIDES
138Flank PainOFFSIDES
139FolliculitisSIDER
140FormicationOFFSIDES
141General physical health deteriorationOFFSIDES
142GoiterOFFSIDES
143HepatitisOFFSIDES
144Hodgkin's disease mixed cellularity stage I supradiaphragmaticOFFSIDES
145HyperkeratosisOFFSIDES
146HypophagiaOFFSIDES
147HypoxiaOFFSIDES
148IleitisOFFSIDES
149Incision site infectionOFFSIDES
150IndurationSIDER
151Infectious MononucleosisOFFSIDES
152InfestationSIDER
153Intervertebral Disc DegenerationOFFSIDES
154Intestinal ObstructionOFFSIDES
155Joint sprainOFFSIDES
156LaparotomyOFFSIDES
157LeukodermaSIDER
158Limb injuryOFFSIDES
159Limb operationOFFSIDES
160Lip exfoliationOFFSIDES
161Loose toothOFFSIDES
162LymphomaOFFSIDES
163Mental status changesOFFSIDES
164Metabolic acidosisOFFSIDES
165Metastatic NeoplasmOFFSIDES
166MiliariaSIDER
167Multi-organ disorderOFFSIDES
168Multiple MyelomaOFFSIDES
169Multiple SclerosisOFFSIDES
170Muscle tightnessOFFSIDES
171Musculoskeletal stiffnessOFFSIDES
172Mycosis FungoidesOFFSIDES
173Nephrogenic Fibrosing DermopathyOFFSIDES
174Neutropenic sepsisOFFSIDES
175Oropharyngeal swellingOFFSIDES
176OsteomyelitisOFFSIDES
177OsteopeniaOFFSIDES
178OsteoporosisOFFSIDES
179Pancreatic enzymes increasedOFFSIDES
180PancreatitisOFFSIDES
181Panic DisorderOFFSIDES
182Pathogen resistanceOFFSIDES
183Performance status decreasedOFFSIDES
184Perirectal abscessOFFSIDES
185PharyngitisSIDER
186PhlebitisOFFSIDES
187Polymyalgia RheumaticaOFFSIDES
188Post procedural hypothyroidismOFFSIDES
189ProctitisOFFSIDES
190Purulent dischargeOFFSIDES
191QRS axis abnormalOFFSIDES
192Rash erythematousCanada Vigilance: 1Canada Vigilance
193RectoceleOFFSIDES
194ScotomaOFFSIDES
195SeptoplastyOFFSIDES
196Sick Sinus SyndromeOFFSIDES
197SinusitisOFFSIDES
198Skin lesionOFFSIDES
199Soft tissue inflammationOFFSIDES
200Spinal column stenosisOFFSIDES
201Squamous cell carcinoma of skinOFFSIDES
202Status EpilepticusOFFSIDES
203Stem cell transplantOFFSIDES
204Stevens-Johnson SyndromeOFFSIDES
205Subcutaneous AbscessOFFSIDES
206SweatingSIDER
207T-Cell LymphomaOFFSIDES
208TendinitisOFFSIDES
209TinnitusOFFSIDES
210TonsillectomyOFFSIDES
211Tooth ExtractionOFFSIDES
212Tooth LossOFFSIDES
213UlcerOFFSIDES
214Umbilical herniaOFFSIDES
215Ventricular hypoplasiaOFFSIDES
216Visual disturbanceOFFSIDES
217Wound InfectionOFFSIDES
218Wound dehiscenceOFFSIDES
219XerosisOFFSIDES
220furuncleOFFSIDES
221kyphosisOFFSIDES
222nervous system disorderSIDER
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120239

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.