MetaADEDB 2.0 @ LMMD
Pentamidine
(YBVNFKZSMZGRAD-UHFFFAOYSA-N)
Structure
SMILES
NC(=N)c1ccc(cc1)OCCCCCOc1ccc(cc1)C(=N)N.OCCS(=O)(=O)O.OCCS(=O)(=O)O
Molecular Formula:
C23H36N4O10S2
Molecular Weight:
592.683
Log P:
4.3775
Hydrogen Bond Acceptor:
14
Hydrogen Bond Donor:
8
TPSA:
284.16
CAS Number(s):
140-64-7
Synonym(s)
1.
Pentamidine
2.
Pentamidine Isethionate
3.
Diamidine
4.
Lomidine
5.
NebuPent
6.
Pentacarinat
7.
Pentam
8.
Pentamidin
9.
Pentamidine Mesylate
External Link(s)
MeSHD010419
PubChem Compound8813
ChEBI7977
CHEMBLCHEMBL361506
KEGGdr:D00834
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1BronchospasmFAERS: 7US FAERS
2WheezingFAERS: 3US FAERS
3Respiratory FailureFAERS: 2OFFSIDES
US FAERS
4DysphoniaFAERS: 1US FAERS
5Respiratory distressFAERS: 1US FAERS
6Throat irritationFAERS: 1
Canada Vigilance: 3		Canada Vigilance
US FAERS
7Unresponsive to stimuliFAERS: 1US FAERS
8Abdominal PainOFFSIDES
9Abnormal visionOFFSIDES
10Acanthamoeba InfectionOFFSIDES
11Acid refluxOFFSIDES
12AcidosisOFFSIDES
13Acute graft versus host disease in liverOFFSIDES
14Acute sinusitisOFFSIDES
15AdenoiditisOFFSIDES
16Alanine Aminotransferase IncreasedOFFSIDES
17AlopeciaOFFSIDES
18AlveolitisOFFSIDES
19AnhedoniaOFFSIDES
20AnhidrosisOFFSIDES
21Anorectal operationOFFSIDES
22AnorexiaOFFSIDES
23ApathyOFFSIDES
24Aphthous StomatitisOFFSIDES
25AppendectomyOFFSIDES
26AppendicitisOFFSIDES
27Arteriovenous fistula aneurysmOFFSIDES
28AscitesOFFSIDES
29AspergillosisOFFSIDES
30AstheniaOFFSIDES
31AstigmatismOFFSIDES
32BK virus infectionOFFSIDES
33Bacillus infectionOFFSIDES
34Bacteria stool identifiedOFFSIDES
35Band neutrophil percentage decreasedOFFSIDES
36Bilirubin conjugated increasedOFFSIDES
37BlepharoptosisOFFSIDES
38Blood GlucoseOFFSIDES
39Blood HIV RNAOFFSIDES
40Blood alkaline phosphatase increasedOFFSIDES
41Blood amylase increasedOFFSIDES
42Blood chloride decreasedOFFSIDES
43Blood chloride increasedOFFSIDES
44Blood cholesterolOFFSIDES
45Blood electrolytes abnormalOFFSIDES
46Blood lactate dehydrogenase increasedOFFSIDES
47Blood osmolarity increasedOFFSIDES
48Blood pH increasedOFFSIDES
49Blood phosphorus increasedOFFSIDES
50Blood sodiumOFFSIDES
51Blood triglycerides increasedOFFSIDES
52Blood uric acid decreasedOFFSIDES
53Blood uric acidOFFSIDES
54Blood zinc decreasedOFFSIDES
55Body TemperatureOFFSIDES
56Bone lesionOFFSIDES
57BradycardiaOFFSIDES
58Brain natriuretic peptide increasedOFFSIDES
59BronchiolitisOFFSIDES
60BronchitisOFFSIDES
61Bronchoalveolar LavageOFFSIDES
62Buccal polypOFFSIDES
63CD4 Lymphocytes DecreasedOFFSIDES
64Cardiac HypertrophyOFFSIDES
65Central line infectionOFFSIDES
66Chest PainCanada Vigilance: 3Canada Vigilance
67Coagulation factor IX level decreasedOFFSIDES
68Coagulation factor VII level decreasedOFFSIDES
69Coagulation factor X level decreasedOFFSIDES
70ColitisOFFSIDES
71Color blindnessOFFSIDES
72ConfabulationOFFSIDES
73Conjunctival depositOFFSIDES
74CraniosynostosisOFFSIDES
75Creatinine renal clearance decreasedOFFSIDES
76Creatinine urine decreasedOFFSIDES
77CryptosporidiosisOFFSIDES
78CyanosisOFFSIDES
79Cytolytic hepatitisOFFSIDES
80Cytomegalovirus chorioretinitisOFFSIDES
81Cytomegalovirus test positiveOFFSIDES
82Deafness NeurosensoryOFFSIDES
83DeafnessOFFSIDES
84DehydrationOFFSIDES
85DiabetesOFFSIDES
86DiarrheaOFFSIDES
87DizzinessCanada Vigilance: 1Canada Vigilance
OFFSIDES
88DrowsinessOFFSIDES
89Dry skinOFFSIDES
90Dysthymic DisorderOFFSIDES
91Electrocardiogram ST segment abnormalOFFSIDES
92Electrocardiogram ST-T changeOFFSIDES
93Electromechanical dissociationOFFSIDES
94Engraftment syndromeOFFSIDES
95EnthesopathyOFFSIDES
96EnuresisOFFSIDES
97Escherichia infectionOFFSIDES
98Facial wastingOFFSIDES
99Failure to ThriveOFFSIDES
100Fat redistributionOFFSIDES
101Feeling ColdOFFSIDES
102FlatulenceOFFSIDES
103Fluid overloadOFFSIDES
104Fungus culture positiveOFFSIDES
105Gamma-Glutamyltransferase IncreasedOFFSIDES
106Gastric ulcerOFFSIDES
107GastroenteritisOFFSIDES
108Gastrointestinal arteriovenous malformationOFFSIDES
109General physical health deteriorationOFFSIDES
110Genital HerpesOFFSIDES
111GliomaOFFSIDES
112GlobulinuriaOFFSIDES
113GoiterOFFSIDES
114GranulocytosisOFFSIDES
115HIV Wasting SyndromeOFFSIDES
116HaematotoxicityOFFSIDES
117HepatectomyOFFSIDES
118Hepatic infection bacterialOFFSIDES
119Hepatitis BOFFSIDES
120HepatitisOFFSIDES
121HepatoblastomaOFFSIDES
122HepatotoxicityOFFSIDES
123HydronephrosisOFFSIDES
124HyperaldosteronismOFFSIDES
125HypertrichosisOFFSIDES
126HypophagiaOFFSIDES
127Immune reconstitution syndromeOFFSIDES
128Impaired gastric emptyingOFFSIDES
129ImpetigoOFFSIDES
130Incision site infectionOFFSIDES
131Infusion site mobility decreasedOFFSIDES
132Intervertebral disc disorderOFFSIDES
133Intraductal papilloma of breastOFFSIDES
134Joint Range of Motion DecreasedOFFSIDES
135Kidney FailureOFFSIDES
136Lactobacillus infectionOFFSIDES
137Leukopenia neonatalOFFSIDES
138Limb injuryOFFSIDES
139Lip erosionOFFSIDES
140LipaseOFFSIDES
141Lipodystrophy acquiredOFFSIDES
142Liver AbscessOFFSIDES
143Liver transplant rejectionOFFSIDES
144Mammary duct ectasiaOFFSIDES
145MedulloblastomaOFFSIDES
146Mental status changesOFFSIDES
147Metapneumovirus infectionOFFSIDES
148Mixed liver injuryOFFSIDES
149Muscle WeaknessOFFSIDES
150Musculoskeletal discomfortOFFSIDES
151Musculoskeletal stiffnessOFFSIDES
152Mycobacterium avium complex immune restoration diseaseOFFSIDES
153MyelitisOFFSIDES
154NasopharyngitisOFFSIDES
155NauseaOFFSIDES
156Neutrophil count decreasedOFFSIDES
157ObstructionOFFSIDES
158Optic NeuritisOFFSIDES
159Optic NeuropathyOFFSIDES
160Oral polypectomyOFFSIDES
161Oropharyngeal painCanada Vigilance: 1Canada Vigilance
162PainOFFSIDES
163PancreatitisOFFSIDES
164ParaplegiaOFFSIDES
165ParathyroidectomyOFFSIDES
166Pericardial effusionOFFSIDES
167PericarditisOFFSIDES
168Pigmentary retinopathyOFFSIDES
169Pneumocystis jiroveci pneumoniaOFFSIDES
170PneumothoraxOFFSIDES
171PolyneuropathyOFFSIDES
172Poor sucking reflexOFFSIDES
173Post procedural urine leakOFFSIDES
174Precocious PubertyOFFSIDES
175Product use issueCanada Vigilance: 3Canada Vigilance
176Prothrombin level decreasedOFFSIDES
177Pseudomonal sepsisOFFSIDES
178QuadriparesisOFFSIDES
179Radiation necrosisOFFSIDES
180RalesOFFSIDES
181Rectal fissureOFFSIDES
182Refusal of treatment by relativeOFFSIDES
183Renal cystOFFSIDES
184Renal tubular disorderOFFSIDES
185Respiratory syncytial virus test positiveOFFSIDES
186RetinitisOFFSIDES
187RhinitisOFFSIDES
188RhinorrheaOFFSIDES
189SchizophreniaOFFSIDES
190Septic ShockOFFSIDES
191Serum SicknessOFFSIDES
192SinusitisOFFSIDES
193Skin IndurationOFFSIDES
194Skin hypertrophyOFFSIDES
195Speech rehabilitationOFFSIDES
196Staphylococcal Scalded Skin SyndromeOFFSIDES
197Stem cell transplantOFFSIDES
198SynostosisOFFSIDES
199Therapeutic product ineffectiveOFFSIDES
200ToxoplasmosisOFFSIDES
201Transfusion ReactionOFFSIDES
202Trichosporon infectionOFFSIDES
203Ultrasound abdomen abnormalOFFSIDES
204Urine osmolarity decreasedOFFSIDES
205Urine uric acid decreasedOFFSIDES
206Venoocclusive diseaseOFFSIDES
207Ventricular hypokinesiaOFFSIDES
208Virus serology test positiveOFFSIDES
209Walking aid userOFFSIDES
210Wheelchair userOFFSIDES
211Wound infection pseudomonasOFFSIDES
212kyphosisOFFSIDES
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