MetaADEDB 2.0 @ LMMD
Estramustine phosphate
(ADFOJJHRTBFFOF-RBRWEJTLSA-N)
Structure
SMILES
ClCCN(C(=O)Oc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2OP(=O)(O)O)C)CCCl
Type(s)
Approved; Investigational
Molecular Formula:
C23H32Cl2NO6P
Molecular Weight:
520.383
Log P:
5.2990
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
2
TPSA:
106.11
CAS Number(s):
4891-15-0
Synonym(s)
1.
Estramustine phosphate
External Link(s)
PubChem Compound259329
BindingDB50333645
ChEBI68643
CHEMBLCHEMBL1756
DrugBankDB14674
DrugCentral1066
ZINC3938713
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Cerebral InfarctionFAERS: 5US FAERS
2Pulmonary EmbolismFAERS: 4US FAERS
3Angina PectorisFAERS: 3US FAERS
4AngioedemaFAERS: 3OFFSIDES
US FAERS
5Myocardial InfarctionFAERS: 3US FAERS
6NauseaFAERS: 3OFFSIDES
US FAERS
7Product use issueFAERS: 3US FAERS
8Alanine Aminotransferase IncreasedFAERS: 2US FAERS
9Aspartate Aminotransferase IncreasedFAERS: 2US FAERS
10HepatitisFAERS: 2OFFSIDES
US FAERS
11Pelvic PainFAERS: 2US FAERS
12PneumoniaFAERS: 2US FAERS
13Pulmonary FibrosisFAERS: 2US FAERS
14Sudden deathFAERS: 2US FAERS
15jaundiceFAERS: 2US FAERS
16Abdominal PainFAERS: 1OFFSIDES
US FAERS
17Anaphylactic shockFAERS: 1US FAERS
18AppendicitisFAERS: 1US FAERS
19AstheniaFAERS: 1US FAERS
20Diet refusalFAERS: 1US FAERS
21Diffuse Large B-Cell LymphomaFAERS: 1US FAERS
22Disease ProgressionFAERS: 1US FAERS
23Embolic strokeFAERS: 1US FAERS
24Enlarged uvulaFAERS: 1US FAERS
25Injection site painFAERS: 1US FAERS
26Liver AbscessFAERS: 1US FAERS
27MalaiseFAERS: 1US FAERS
28Medication ErrorFAERS: 1US FAERS
29MeningiomaFAERS: 1US FAERS
30MetrorrhagiaFAERS: 1US FAERS
31Mixed liver injuryFAERS: 1US FAERS
32Musculoskeletal PainFAERS: 1OFFSIDES
US FAERS
33Penile swellingFAERS: 1US FAERS
34SplenomegalyFAERS: 1US FAERS
35Transaminases increasedFAERS: 1OFFSIDES
US FAERS
36Urinary RetentionFAERS: 1US FAERS
37UrticariaFAERS: 1US FAERS
38VomitingFAERS: 1US FAERS
39Abdominal InfectionOFFSIDES
40Abdominal discomfortOFFSIDES
41AbscessOFFSIDES
42Acute respiratory failureOFFSIDES
43AgraphiaOFFSIDES
44AlopeciaOFFSIDES
45AnorexiaOFFSIDES
46AnxietyOFFSIDES
47AphagiaOFFSIDES
48AsphyxiaOFFSIDES
49Benign neoplasm of bladderOFFSIDES
50Biopsy bone abnormalOFFSIDES
51Blood GlucoseOFFSIDES
52Blood albumin increasedOFFSIDES
53Blood alkaline phosphatase increasedOFFSIDES
54Blood beta-D-glucan increasedOFFSIDES
55Blood chloride decreasedOFFSIDES
56Blood potassium increasedOFFSIDES
57Blood urea increasedOFFSIDES
58Bone marrow depressionOFFSIDES
59Bone painOFFSIDES
60Bowel movement irregularityOFFSIDES
61Brain natriuretic peptide increasedOFFSIDES
62BronchiectasisOFFSIDES
63BronchitisOFFSIDES
64Cancer PainOFFSIDES
65Cataract operationOFFSIDES
66Cerebral atrophyOFFSIDES
67Cervicobrachial syndromeOFFSIDES
68Chest PainOFFSIDES
69CholangiolitisOFFSIDES
70CholecystitisOFFSIDES
71Clostridium difficile colitisOFFSIDES
72ColitisOFFSIDES
73Cyst removalOFFSIDES
74CystOFFSIDES
75DebridementOFFSIDES
76DemyelinationOFFSIDES
77Dental FistulaOFFSIDES
78Dental abscessOFFSIDES
79Dental cariesOFFSIDES
80Dental prosthesis placementOFFSIDES
81DiarrheaOFFSIDES
82Disseminated Intravascular CoagulationOFFSIDES
83DiverticulumOFFSIDES
84DrowsinessOFFSIDES
85DysuriaOFFSIDES
86EmbolismOFFSIDES
87EncephalomalaciaOFFSIDES
88Erectile dysfunctionOFFSIDES
89ExcoriationOFFSIDES
90Failure to ThriveOFFSIDES
91FormicationOFFSIDES
92Gingival erythemaOFFSIDES
93GliosisOFFSIDES
94Heat ExhaustionOFFSIDES
95Hepatic congestionOFFSIDES
96Hepatic necrosisOFFSIDES
97Hormone level abnormalOFFSIDES
98Hypertensive angiopathyOFFSIDES
99HypogeusiaOFFSIDES
100InfectionOFFSIDES
101LeukoencephalopathyOFFSIDES
102Leukopenia neonatalOFFSIDES
103Limb injuryOFFSIDES
104LymphomaOFFSIDES
105Malignant neoplasm progressionOFFSIDES
106Mental impairmentOFFSIDES
107Metabolic acidosisOFFSIDES
108Metastases to adrenalsOFFSIDES
109Metastatic painOFFSIDES
110Muscle strainOFFSIDES
111MyelodysplasiaOFFSIDES
112NasopharyngitisOFFSIDES
113NeuralgiaOFFSIDES
114Neutropenic sepsisOFFSIDES
115Nutritional condition abnormalOFFSIDES
116Oral Cavity FistulaOFFSIDES
117Oral infectionOFFSIDES
118Orthosis userOFFSIDES
119OsteomyelitisOFFSIDES
120OsteopeniaOFFSIDES
121PancreatitisOFFSIDES
122Pharyngolaryngeal PainOFFSIDES
123Physical disabilityOFFSIDES
124PolyuriaOFFSIDES
125Poor quality drug administeredOFFSIDES
126ProctitisOFFSIDES
127Prostate cancer recurrentOFFSIDES
128Pulmonary congestionOFFSIDES
129Pulmonary radiation injuryOFFSIDES
130Purulent dischargeOFFSIDES
131Renal cystOFFSIDES
132Septic ShockOFFSIDES
133SinusitisOFFSIDES
134Skin lacerationOFFSIDES
135Spinal column stenosisOFFSIDES
136Spinal haemangiomaOFFSIDES
137Supraventricular tachycardiaOFFSIDES
138TendinitisOFFSIDES
139Thoracic vertebral fractureOFFSIDES
140Tooth ExtractionOFFSIDES
141Urine flow decreasedOFFSIDES
142VertebroplastyOFFSIDES
143Wrong drug administeredOFFSIDES
144kyphosisOFFSIDES
145liposarcomaOFFSIDES
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