MetaADEDB 2.0 @ LMMD
Cyproheptadine
(JJCFRYNCJDLXIK-UHFFFAOYSA-N)
Structure
SMILES
CN1CCC(=C2c3ccccc3C=Cc3c2cccc3)CC1
Type(s)
Approved
ATC code(s)
R06AX02
Molecular Formula:
C21H21N
Molecular Weight:
287.398
Log P:
4.6358
Hydrogen Bond Acceptor:
1
Hydrogen Bond Donor:
0
TPSA:
3.24
CAS Number(s):
129-03-3; 969-33-5; 41354-29-4
Synonym(s)
1.
Cyproheptadine
2.
Antergan
3.
Dihexazin
4.
Periactin
5.
Peritol
6.
Viternum
External Link(s)
MeSHD003533
PubChem Compound2913
BindingDB50017721
ChEBI4046
CHEMBLCHEMBL516
DrugBankDB00434
DrugCentral765
IUPHAR/BPS Guide to PHARMACOLOGY277
KEGGcpd:C06935
dr:D07765
Therapeutic Target DatabaseD00TLN
ZINC968264
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Product use issueFAERS: 4US FAERS
2AgitationFAERS: 2SIDER
US FAERS
3DeliriumFAERS: 22927404CTD
US FAERS
4HeadacheFAERS: 2SIDER
US FAERS
5MydriasisFAERS: 2642945CTD
US FAERS
6Obsessive-Compulsive DisorderFAERS: 2US FAERS
7Sinus TachycardiaFAERS: 2US FAERS
8TachycardiaFAERS: 2642945CTD
SIDER
US FAERS
9Toxicity to various agentsFAERS: 2US FAERS
10Anti-transglutaminase antibody increasedFAERS: 1US FAERS
11Burkholderia cepacia complex infectionFAERS: 1US FAERS
12DizzinessFAERS: 1SIDER
US FAERS
13Drug DependenceFAERS: 1US FAERS
14Drug withdrawal syndromeFAERS: 1US FAERS
15DysarthriaFAERS: 1US FAERS
16EczemaFAERS: 1US FAERS
17Feeling abnormalFAERS: 1SIDER
US FAERS
18Flat affectFAERS: 1US FAERS
19HypopituitarismFAERS: 1US FAERS
20Increased bronchial secretionFAERS: 1US FAERS
21Initial insomniaFAERS: 1US FAERS
22Intentional product misuseFAERS: 1US FAERS
23Mood swingsFAERS: 1US FAERS
24NeutropeniaFAERS: 1US FAERS
25OverdoseFAERS: 1US FAERS
26PoisoningFAERS: 1US FAERS
27Respiratory distressFAERS: 1US FAERS
28RestlessnessFAERS: 1US FAERS
29SomnolenceFAERS: 1SIDER
US FAERS
30SwellingFAERS: 1US FAERS
31Therapeutic response unexpectedFAERS: 1US FAERS
32treatment failureFAERS: 1US FAERS
33Abdominal PainCanada Vigilance: 1Canada Vigilance
34Abdominal discomfortOFFSIDES
35Acetonaemic vomitingOFFSIDES
36Acid refluxOFFSIDES
37AcromegalyOFFSIDES
38ActinomycosisOFFSIDES
39Acute otitis mediaOFFSIDES
40Acute sinusitisOFFSIDES
41AdenoiditisOFFSIDES
42AgranulocytosisSIDER
43Alanine Aminotransferase IncreasedOFFSIDES
44Alcohol withdrawal syndromeOFFSIDES
45Altered state of consciousnessOFFSIDES
46AlveolitisOFFSIDES
47AnhedoniaOFFSIDES
48Anorexia2565491
20002750		CTD
OFFSIDES
SIDER
49Anti-erythropoietin antibody positiveOFFSIDES
50Anticholinergic SyndromeOFFSIDES
51Antiphospholipid SyndromeOFFSIDES
52Antiviral drug level above therapeuticOFFSIDES
53AnxietyOFFSIDES
54Aortic Valve Insufficiency19346455CTD
55AppendectomyOFFSIDES
56ArthralgiaCanada Vigilance: 1Canada Vigilance
57Arthropod biteOFFSIDES
58AstheniaSIDER
59AstigmatismOFFSIDES
60Ataxia642945CTD
61Athetosis2927404CTD
62AuraOFFSIDES
63Autistic Disorder15068403CTD
64Autoimmune thyroiditisOFFSIDES
65AutomatismOFFSIDES
66BlepharoptosisOFFSIDES
67Blood corticotrophinOFFSIDES
68Blood creatine phosphokinase increasedOFFSIDES
69Blood erythropoietin increasedOFFSIDES
70Blood glucose fluctuationOFFSIDES
71Body TemperatureOFFSIDES
72Bone marrow depressionOFFSIDES
73Bone painOFFSIDES
74Bradycardia1451572CTD
75BronchiolitisOFFSIDES
76BronchitisOFFSIDES
77BruxismOFFSIDES
78Cardiac HypertrophyOFFSIDES
79Cardiac function test abnormalOFFSIDES
80Cardiovascular insufficiencyOFFSIDES
81Cartilage injuryOFFSIDES
82Catalepsy1033567
1168927		CTD
83Catatonia8887967CTD
84Catheter related infectionOFFSIDES
85Central Nervous System InfectionOFFSIDES
86Cerebral ThrombosisOFFSIDES
87Chemical and Drug Induced Liver Injury3046986
3559100		CTD
88Chest discomfortSIDER
89Chest tightnessSIDER
90Child Behavior Disorders9628088CTD
91ChillsSIDER
92Cholestasis3559100CTD
SIDER
93Chorea2927404CTD
94Clostridium difficile colitisOFFSIDES
95Color blindnessOFFSIDES
96Compulsive shoppingOFFSIDES
97Conjunctival depositOFFSIDES
98ConstipationSIDER
99Conversion disorderSIDER
100Creatinine urine decreasedOFFSIDES
101CryingOFFSIDES
102Cushing Syndrome69087
6327962
7915698		CTD
103CyanosisOFFSIDES
104Deafness NeurosensoryOFFSIDES
105DebridementOFFSIDES
106Delirium febrileOFFSIDES
107Delusional disorder, persecutory typeOFFSIDES
108DemyelinationOFFSIDES
109Dental cariesOFFSIDES
110Dental prosthesis placementOFFSIDES
111DependenceOFFSIDES
112Depressed Level of ConsciousnessOFFSIDES
113Depressive disorder1525285
2016249		CTD
114DermatitisSIDER
115DiplopiaSIDER
116Disease recurrenceOFFSIDES
117DrowsinessOFFSIDES
SIDER
118Drug ToleranceOFFSIDES
119Drug delivery system malfunctionOFFSIDES
120Drug dispensing errorOFFSIDES
121Drug toxicityOFFSIDES
122Drug withdrawal headacheOFFSIDES
123DysgeusiaOFFSIDES
124DyslaliaOFFSIDES
125DyspepsiaSIDER
126Echocardiogram abnormalOFFSIDES
127Economic problemOFFSIDES
128Edema7508328
7907874
9274987		CTD
129Emotional distressOFFSIDES
130Enterococcal sepsisOFFSIDES
131Enterovesical FistulaOFFSIDES
132EnuresisOFFSIDES
133Epigastric distressSIDER
134EpistaxisOFFSIDES
135Erectile dysfunctionOFFSIDES
136Erythema MultiformeOFFSIDES
137Euphoric moodSIDER
138FatigueSIDER
139Feeding and Eating Disorders264413CTD
140Fever139615CTD
141FibromyalgiaOFFSIDES
142Fistula repairOFFSIDES
143FlatulenceCanada Vigilance: 1Canada Vigilance
144FolliculitisOFFSIDES
145GamblingOFFSIDES
146Gastric ulcerOFFSIDES
147GastroenteritisOFFSIDES
148General physical health deteriorationOFFSIDES
149Gingival HypertrophyCanada Vigilance: 1Canada Vigilance
150GlobulinuriaOFFSIDES
151Hallucinations642945
3631331		CTD
152Head BangingOFFSIDES
153HemiparesisOFFSIDES
154HepatectomyOFFSIDES
155HepatitisSIDER
156HepatoblastomaOFFSIDES
157HepatotoxicityOFFSIDES
158Hormone level abnormalOFFSIDES
159Hyperemesis GravidarumOFFSIDES
160HypertrichosisOFFSIDES
161Hypotension1451572CTD
SIDER
162Hypoxia2367283CTD
163HysteriaSIDER
164Impaired gastric emptyingOFFSIDES
165ImpetigoOFFSIDES
166IncontinenceOFFSIDES
167Infectious MononucleosisOFFSIDES
168Injection site dermatitisOFFSIDES
169Intention tremorOFFSIDES
170LabyrinthitisSIDER
171Lack of spontaneous speechOFFSIDES
172Large intestine perforationOFFSIDES
173Leukopenia neonatalOFFSIDES
174LeukopeniaSIDER
175Liver palpable subcostalOFFSIDES
176Lung consolidationOFFSIDES
177Lymphocyte percentage decreasedOFFSIDES
178Malaria23129054CTD
179Mental retardation severity unspecifiedOFFSIDES
180Middle insomniaOFFSIDES
181Monocyte percentage decreasedOFFSIDES
182Multiple SclerosisOFFSIDES
183Muscle tightnessOFFSIDES
184Musculoskeletal discomfortOFFSIDES
185NasopharyngitisOFFSIDES
186NauseaSIDER
187Nelson Syndrome6243392CTD
188NervousnessSIDER
189NeuritisSIDER
190Neurological decompensationOFFSIDES
191OliguriaOFFSIDES
192Oral Cavity FistulaOFFSIDES
193Oral torusOFFSIDES
194OsteomyelitisOFFSIDES
195PROTHROMBIN TIMEOFFSIDES
196PallorOFFSIDES
197PalpitationsSIDER
198PapillomaOFFSIDES
199ParasomniaOFFSIDES
200Pelvic abscessOFFSIDES
201Personality ChangeOFFSIDES
202Personality Disorders573894CTD
203Pharyngolaryngeal PainOFFSIDES
204Pigmentary retinopathyOFFSIDES
205PneumothoraxOFFSIDES
206Precocious PubertyOFFSIDES
207Primary sequestrumOFFSIDES
208Pruritus12499574CTD
209Psychiatric symptomOFFSIDES
210Psychoses, Substance-Induced69087
264413
11116800		CTD
211Psychotic Disorders8935814CTD
212Purulent dischargeOFFSIDES
213Refusal of treatment by relativeOFFSIDES
214Renal tubular disorderOFFSIDES
215ReticulocytopeniaOFFSIDES
216RhinitisOFFSIDES
217ScreamingOFFSIDES
218Seizures20002750
22951378		CTD
219Serotonin Syndrome17403991
18585543
20002750		CTD
220ShockSIDER
221Sinus headacheOFFSIDES
222SoliloquyOFFSIDES
223Speech rehabilitationOFFSIDES
224StaringOFFSIDES
225Stomatococcal infectionOFFSIDES
226Substance Withdrawal Syndrome

View details

4735135
11116800
12465085
19240673
 		CTD
227SyncopeSIDER
228Synovial CystOFFSIDES
229Temperature regulation disorderOFFSIDES
230Tension HeadacheOFFSIDES
231TensionSIDER
232ThrombocytopeniaSIDER
233TinnitusSIDER
234Tooth ExtractionOFFSIDES
235Tooth InfectionOFFSIDES
236Tooth LossOFFSIDES
237Tremor10762688CTD
SIDER
238Unresponsive to verbal stimuliOFFSIDES
239Upper respiratory tract inflammationOFFSIDES
240Urinary RetentionSIDER
241Urination Disorders7994334CTD
242Urine osmolarity decreasedOFFSIDES
243Urine uric acid decreasedOFFSIDES
244UrticariaSIDER
245Vaginal burning sensationOFFSIDES
246VertigoSIDER
247Visual disturbanceOFFSIDES
248VomitingCanada Vigilance: 2Canada Vigilance
SIDER
249WheezingSIDER
250Wound infection pseudomonasOFFSIDES
251jaundice630329
3046986		CTD
SIDER
252kyphosisOFFSIDES
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