MetaADEDB 2.0 @ LMMD
Norfloxacin
(OGJPXUAPXNRGGI-UHFFFAOYSA-N)
Structure
SMILES
CCn1cc(C(=O)O)c(=O)c2c1cc(N1CCNCC1)c(c2)F
Type(s)
Approved
ATC code(s)
J01MA06; J01RA13; S01AE02
Molecular Formula:
C16H18FN3O3
Molecular Weight:
319.331
Log P:
1.6621
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
74.57
CAS Number(s):
70458-96-7
Synonym(s)
1.
Norfloxacin
2.
AM-0715
3.
AM-715
4.
MK-0366
5.
MK-366
6.
MK0366
7.
MK366
8.
Noroxin
9.
AM 0715
10.
AM 715
11.
AM0715
12.
MK 0366
13.
MK 366
External Link(s)
MeSHD009643
PubChem Compound6919051
4539
BindingDB50045000
ChEBI100246
CHEMBLCHEMBL9
DrugBankDB01059
DrugCentral1967
KEGGcpd:C06687
dr:D00210
Therapeutic Target DatabaseD0Q2PE
ZINC3742
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug exposure during pregnancyFAERS: 15OFFSIDES
US FAERS
2ArthralgiaFAERS: 9
Canada Vigilance: 3		Canada Vigilance
SIDER
US FAERS
3HeadacheFAERS: 6
Canada Vigilance: 3		3605158CTD
SIDER
Canada Vigilance
US FAERS
4MyalgiaFAERS: 5
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
5PruritusFAERS: 4
Canada Vigilance: 6		Canada Vigilance
SIDER
US FAERS
6AngioedemaFAERS: 3
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
7DehydrationFAERS: 3US FAERS
8ErythemaFAERS: 3SIDER
US FAERS
9No adverse eventFAERS: 3US FAERS
10Rash erythematousFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
11Retinal DetachmentFAERS: 3US FAERS
12Shoulder PainFAERS: 3OFFSIDES
US FAERS
13Urinary tract infectionFAERS: 3US FAERS
14muscle injuryFAERS: 3US FAERS
15AgeusiaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
16Anaphylactic shockFAERS: 2SIDER
US FAERS
17Bone marrow depressionFAERS: 2US FAERS
18Chest PainFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
19Cleft PalateFAERS: 2OFFSIDES
US FAERS
20Drug prescribing errorFAERS: 2US FAERS
21Electrolyte imbalanceFAERS: 2US FAERS
22Incorrect route of drug administrationFAERS: 2US FAERS
23Maternal exposure during pregnancyFAERS: 2US FAERS
24Musculoskeletal PainFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
25PancytopeniaFAERS: 2US FAERS
26Product solubility abnormalFAERS: 2US FAERS
27PurpuraFAERS: 2US FAERS
28RetchingFAERS: 2US FAERS
29StomatitisFAERS: 2SIDER
US FAERS
30Vascular purpuraFAERS: 2US FAERS
31Wrong technique in drug usage processFAERS: 2US FAERS
32jaundiceFAERS: 2SIDER
US FAERS
33Abdominal PainFAERS: 1SIDER
US FAERS
34Acute psychosisFAERS: 1US FAERS
35Alanine aminotransferase abnormalFAERS: 1US FAERS
36AnxietyFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
37Aspartate aminotransferase abnormalFAERS: 1US FAERS
38AstheniaFAERS: 1
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
39Back PainFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
40Bipolar DisorderFAERS: 1US FAERS
41BlepharitisFAERS: 1OFFSIDES
US FAERS
42Blood alkaline phosphatase increasedFAERS: 1SIDER
US FAERS
43Cartilage atrophyFAERS: 1US FAERS
44CholestasisFAERS: 110445586CTD
SIDER
US FAERS
45Clostridium colitisFAERS: 1US FAERS
46ConjunctivitisFAERS: 1SIDER
US FAERS
47Cytolytic hepatitisFAERS: 1OFFSIDES
US FAERS
48DeafnessFAERS: 1SIDER
US FAERS
49DiplopiaFAERS: 1SIDER
US FAERS
50DizzinessFAERS: 1
Canada Vigilance: 9		3605158CTD
SIDER
Canada Vigilance
US FAERS
51Drug administration errorFAERS: 1US FAERS
52Drug dose omissionFAERS: 1US FAERS
53Drug ineffectiveFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
54Dry skinFAERS: 1US FAERS
55EpilepsyFAERS: 1OFFSIDES
US FAERS
56Eyelids pruritusFAERS: 1US FAERS
57FatigueFAERS: 1SIDER
US FAERS
58FlushingFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
59Gamma-Glutamyltransferase IncreasedFAERS: 1US FAERS
60Gamma-glutamyltransferase abnormalFAERS: 1US FAERS
61HemiparesisFAERS: 1US FAERS
62Hepatic EncephalopathyFAERS: 1US FAERS
63HepatitisFAERS: 110445586
11151924		CTD
OFFSIDES
SIDER
US FAERS
64Hip surgeryFAERS: 1US FAERS
65Inappropriate schedule of drug administrationFAERS: 1US FAERS
66Incorrect drug administration durationFAERS: 1US FAERS
67Ligament painFAERS: 1US FAERS
68Limb discomfortFAERS: 1US FAERS
69Memory impairmentFAERS: 1US FAERS
70Middle insomniaFAERS: 1US FAERS
71Neck PainFAERS: 1US FAERS
72Neonatal respiratory depressionFAERS: 1US FAERS
73Ocular ToxicityFAERS: 1US FAERS
74PainFAERS: 1
Canada Vigilance: 2		Canada Vigilance
US FAERS
75Pathogen resistanceFAERS: 1OFFSIDES
US FAERS
76Pelvic PainFAERS: 1US FAERS
77PolyarthritisFAERS: 1US FAERS
78PregnancyFAERS: 1US FAERS
79Rotator cuff syndromeFAERS: 1US FAERS
80SinusitisFAERS: 1US FAERS
81Skin reactionFAERS: 1US FAERS
82SneezingFAERS: 1US FAERS
83SomnolenceFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
84Status EpilepticusFAERS: 1OFFSIDES
US FAERS
85Suicide attemptFAERS: 1US FAERS
86ThrombocytopeniaFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
87TinnitusFAERS: 1
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
88TremorFAERS: 1SIDER
US FAERS
89Troponin increasedFAERS: 1US FAERS
90Type II hypersensitivityFAERS: 1US FAERS
91Type III immune complex mediated reactionFAERS: 1US FAERS
92Vasculitic rashFAERS: 1US FAERS
93VertigoFAERS: 1SIDER
US FAERS
94VomitingFAERS: 1SIDER
US FAERS
95Vulvovaginal discomfortFAERS: 1US FAERS
96kyphosisFAERS: 1US FAERS
97Abdominal CrampsSIDER
98AcidosisOFFSIDES
99Acute Coronary SyndromeSIDER
100Acute kidney injuryCanada Vigilance: 118045047CTD
Canada Vigilance
101Acute respiratory failureOFFSIDES
102AgitationCanada Vigilance: 2Canada Vigilance
SIDER
103AgranulocytosisSIDER
104Alanine Aminotransferase IncreasedOFFSIDES
105AlbuminuriaSIDER
106Alcoholic IntoxicationOFFSIDES
107Amniotic Band SyndromeOFFSIDES
108Anaphylactoid ReactionSIDER
109AnisocytosisOFFSIDES
110Anorectal discomfortSIDER
111AnorexiaSIDER
112AnoxiaOFFSIDES
113Anticonvulsant drug level above therapeuticOFFSIDES
114Anxiety Disorders17975693CTD
115AphasiaSIDER
116Aphthous StomatitisOFFSIDES
117Arteriopathic diseaseOFFSIDES
118ArthritisSIDER
119Aspartate Aminotransferase IncreasedSIDER
120AsterixisOFFSIDES
121AtaxiaCanada Vigilance: 1Canada Vigilance
SIDER
122AtelectasisOFFSIDES
123AuraOFFSIDES
124AutomatismOFFSIDES
125Bacillus infectionOFFSIDES
126Bacteriuria3481333CTD
127Biopsy bone abnormalOFFSIDES
128Blood chloride decreasedOFFSIDES
129Blood creatine phosphokinase increasedOFFSIDES
130Blood creatinine increasedCanada Vigilance: 1Canada Vigilance
OFFSIDES
SIDER
131Blood electrolytes decreasedOFFSIDES
132Blood lactate dehydrogenase increasedSIDER
133Blood pH decreasedOFFSIDES
134Blood pressure immeasurableOFFSIDES
135Blood sodiumOFFSIDES
136Blood triglycerides increasedOFFSIDES
137Blood urea increasedSIDER
138BursitisSIDER
139CandiduriaOFFSIDES
SIDER
140Cardiac valve vegetationOFFSIDES
141Catheter related complicationOFFSIDES
142Catheter site erythemaOFFSIDES
143Cell DeathOFFSIDES
144Central line infectionOFFSIDES
145Cerebral artery occlusionOFFSIDES
146Cerebral atrophyOFFSIDES
147Cerebral disorderOFFSIDES
148Chest wall painOFFSIDES
149ChillsSIDER
150CholangiolitisOFFSIDES
151Cholestatic liver injuryOFFSIDES
152ChromaturiaOFFSIDES
153Citrobacter infectionOFFSIDES
154Clostridium difficile colitisOFFSIDES
155ConfabulationOFFSIDES
156Conjunctival depositOFFSIDES
157Consciousness fluctuatingOFFSIDES
158ConstipationSIDER
159Creatinine increasedSIDER
160CrystalluriaSIDER
161Cystitis escherichiaOFFSIDES
162Cystitis11409139CTD
163DermatitisSIDER
164DisorientationSIDER
165Diverticular perforationOFFSIDES
166DiverticulosisOFFSIDES
167DrowsinessSIDER
168Drug Eruptions11792017CTD
169Drug exposure via breast milkOFFSIDES
170DysarthriaSIDER
171DysgeusiaSIDER
172DyspareuniaOFFSIDES
173Dyspepsia3605158CTD
SIDER
174DysphasiaSIDER
175DystoniaOFFSIDES
176EcholaliaOFFSIDES
177Edema7885154CTD
178EmbolismOFFSIDES
179Embryo Loss3605158CTD
180EndophthalmitisOFFSIDES
181Enterococcal sepsisOFFSIDES
182EnthesopathyOFFSIDES
183Eosinophilia11151924CTD
SIDER
184Eosinophilic PneumoniaOFFSIDES
185Eosinophilic cystitisOFFSIDES
186EpiglottitisOFFSIDES
187EpiscleritisOFFSIDES
188Epstein-Barr virus associated lymphoproliferative disorderOFFSIDES
189Erythema MultiformeOFFSIDES
SIDER
190Erythema NodosumCanada Vigilance: 1Canada Vigilance
OFFSIDES
191Escherichia infectionOFFSIDES
192Euphoric moodSIDER
193Explosive personality disorderSIDER
194Eye painCanada Vigilance: 1Canada Vigilance
OFFSIDES
SIDER
195Eyelid painOFFSIDES
196Facial paralysisCanada Vigilance: 1Canada Vigilance
197Febrile NeutropeniaOFFSIDES
198Febrile bone marrow aplasiaOFFSIDES
199Feeling abnormalSIDER
200FlatulenceSIDER
201Gastrointestinal Diseases1621752CTD
202Gastrointestinal PainSIDER
203General physical health deteriorationOFFSIDES
204Glomerulonephritis8893181CTD
205GlycosuriaSIDER
206GoiterOFFSIDES
207Gonorrhea8335312CTD
208Granuloma11151924CTD
209Guillain-Barre SyndromeSIDER
210Hallucinations9282621
11198813		CTD
211HeartburnSIDER
212Hematuria11015000CTD
213HemiplegiaOFFSIDES
214Hepatic necrosisSIDER
215Hepatitis BOFFSIDES
216HydronephrosisOFFSIDES
217HyperkinesiaCanada Vigilance: 1Canada Vigilance
218HyperparathyroidismOFFSIDES
219HypersensitivitySIDER
220HyperventilationCanada Vigilance: 1Canada Vigilance
221HypothyroidismCanada Vigilance: 1Canada Vigilance
222Impaired self-careOFFSIDES
223Infusion site mobility decreasedOFFSIDES
224Infusion site rashOFFSIDES
225Injection site dermatitisOFFSIDES
226Intermittent Explosive DisorderSIDER
227Intestinal FistulaOFFSIDES
228Jaundice, Obstructive9820434CTD
229Joint stiffnessCanada Vigilance: 1Canada Vigilance
SIDER
230Kidney FailureOFFSIDES
231Lactic dehydrogenase activity increasedSIDER
232LethargyCanada Vigilance: 1Canada Vigilance
233Leukocytoclastic vasculitisSIDER
234LeukoencephalopathyOFFSIDES
235LeukopeniaSIDER
236LightheadednessSIDER
237Livedo ReticularisOFFSIDES
238Liver Cirrhosis, Alcoholic12899586CTD
239Low Back Pain11015000CTD
240LymphoceleOFFSIDES
241MacrocytosisOFFSIDES
242MalabsorptionOFFSIDES
243MalaiseCanada Vigilance: 1Canada Vigilance
244MeningorrhagiaOFFSIDES
245Metabolic acidosisSIDER
246Motor retardationOFFSIDES
247Multiple drug overdose intentionalOFFSIDES
248Muscle FatigueOFFSIDES
249Musculoskeletal discomfortSIDER
250MutismOFFSIDES
251Myasthenia GravisSIDER
252MyelitisCanada Vigilance: 1Canada Vigilance
253Myocardial InfarctionSIDER
254MyoclonusSIDER
255NauseaCanada Vigilance: 53605158CTD
SIDER
Canada Vigilance
256Necrosis9812728CTD
257Nephritis, Interstitial9406312
11015000
18045047		CTD
258Nephrotic Syndrome7885154
8893181		CTD
259Nerve Degeneration9812728CTD
260Nerve injuryCanada Vigilance: 1Canada Vigilance
261NervousnessSIDER
262Neuroleptic Malignant SyndromeOFFSIDES
263NeutropeniaSIDER
264Night sweatsCanada Vigilance: 1Canada Vigilance
265NystagmusSIDER
266ObstructionOFFSIDES
267Oliguria7885154CTD
268PCO2 decreasedOFFSIDES
269PallorCanada Vigilance: 1Canada Vigilance
OFFSIDES
270PalpitationsCanada Vigilance: 3Canada Vigilance
SIDER
271PancreatitisSIDER
272PemphigusOFFSIDES
273PeriarthritisOFFSIDES
274PhototoxicitySIDER
275PolyneuropathySIDER
276Portal Vein ThrombosisOFFSIDES
277Prescribed overdoseOFFSIDES
278PriapismOFFSIDES
279Protein urine presentSIDER
280Proteinuria7885154
8893181
11015000		CTD
SIDER
281Proteus Infections3224396CTD
282Pseudomonas Infections3382111CTD
283Pulmonary artery thrombosisOFFSIDES
284Purulent dischargeOFFSIDES
285Pyelonephritis1621752CTD
OFFSIDES
286Pyuria3481333CTD
287Renal ColicOFFSIDES
SIDER
288Rhabdomyolysis8976986
11409139		CTD
OFFSIDES
289Rheumatoid NoduleOFFSIDES
290Seizures

View details

1312320
1622442
1851545
3382111
8026738
9023315
9756792
9812728
12199111
12791190
14576142
16824509
 		CTD
291Sensorimotor disorderOFFSIDES
292SeromaOFFSIDES
293Serum SicknessOFFSIDES
294Serum urea increasedSIDER
295Skin test negativeOFFSIDES
296Skin test positiveOFFSIDES
297Spina BifidaOFFSIDES
298Stem cell transplantOFFSIDES
299Stevens-Johnson Syndrome1433924
25811541		CTD
SIDER
300SwellingCanada Vigilance: 1Canada Vigilance
SIDER
301TachycardiaCanada Vigilance: 2Canada Vigilance
302TendinitisOFFSIDES
303TensionSIDER
304Tongue exfoliationOFFSIDES
305Toxic Epidermal NecrolysisSIDER
306Transfusion ReactionOFFSIDES
307Ultrasound abdomen abnormalOFFSIDES
308Ureteral necrosisOFFSIDES
309Urethritis8335312CTD
310Urinary protein increasedSIDER
311UrticariaCanada Vigilance: 311792017CTD
SIDER
Canada Vigilance
312VasculitisSIDER
313Ventricular arrhythmiaSIDER
314Visual ImpairmentSIDER
315Visual disturbanceOFFSIDES
SIDER
316Vitamin B 12 DeficiencyOFFSIDES
317VitritisOFFSIDES
318Vulvovaginal drynessOFFSIDES
319Vulvovaginal mycotic infectionSIDER
320Vulvovaginal swellingSIDER
321White blood cell count decreasedSIDER
322pseudomembranous colitisSIDER
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