MetaADEDB 2.0 @ LMMD
4-[(1R)-2-[6-[2-[(2,6-Dichlorophenyl)methoxy]ethoxy]hexylamino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol;[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate;diphenyl-[1-(2-phenylmethoxyethyl)-1-azoniabicyclo[2.2.2]octan-4-yl]methanol
(MQFIOYAUCGYUIP-NSHYJIQFSA-N)
Structure
SMILES
OC(C12CC[N+](CC1)(CC2)CCOCc1ccccc1)(c1ccccc1)c1ccccc1.OCc1cc(ccc1O)[C@H](CNCCCCCCOCCOCc1c(Cl)cccc1Cl)O.FCSC(=O)[C@@]1(OC(=O)c2ccco2)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)F)F
Molecular Formula:
C80H96Cl2F3N2O13S+
Molecular Weight:
1453.590
Log P:
15.0246
Hydrogen Bond Acceptor:
15
Hydrogen Bond Donor:
6
TPSA:
239.75
CAS Number(s):
N/A
Synonym(s)
1.
4-[(1R)-2-[6-[2-[(2,6-Dichlorophenyl)methoxy]ethoxy]hexylamino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol;[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate;diphenyl-[1-(2-phenylmethoxyethyl)-1-azoniabicyclo[2.2.2]octan-4-yl]methanol
External Link(s)
PubChem Compound122403924
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1PneumoniaFAERS: 124US FAERS
2Drug ineffectiveFAERS: 123US FAERS
3Wrong technique in device usage processFAERS: 104US FAERS
4Product dispensing errorFAERS: 93US FAERS
5Product dose omissionFAERS: 86US FAERS
6Drug dispensing errorFAERS: 73US FAERS
7Product complaintFAERS: 62US FAERS
8DysphoniaFAERS: 54US FAERS
9Product label confusionFAERS: 54US FAERS
10Product packaging confusionFAERS: 47US FAERS
11Product use in unapproved indicationFAERS: 47US FAERS
12MalaiseFAERS: 42US FAERS
13Circumstance or information capable of leading to medication errorFAERS: 33US FAERS
14HeadacheFAERS: 31US FAERS
15Oropharyngeal painFAERS: 30US FAERS
16Chest PainFAERS: 27US FAERS
17DizzinessFAERS: 24US FAERS
18Lower respiratory tract infectionFAERS: 24US FAERS
19OverdoseFAERS: 24US FAERS
20Myocardial InfarctionFAERS: 22US FAERS
21Throat irritationFAERS: 22US FAERS
22Back PainFAERS: 21US FAERS
23Cerebrovascular accidentFAERS: 20US FAERS
24FatigueFAERS: 20US FAERS
25NasopharyngitisFAERS: 20US FAERS
26NauseaFAERS: 17US FAERS
27Chest discomfortFAERS: 16US FAERS
28Productive CoughFAERS: 16US FAERS
29TremorFAERS: 16US FAERS
30ChokingFAERS: 15US FAERS
31Peripheral swellingFAERS: 14US FAERS
32AsthmaFAERS: 13US FAERS
33InfluenzaFAERS: 13US FAERS
34Oral candidiasisFAERS: 13US FAERS
35Urinary RetentionFAERS: 13US FAERS
36Visual ImpairmentFAERS: 13US FAERS
37Eye painFAERS: 12US FAERS
38Therapy cessationFAERS: 12US FAERS
39Drug effect incompleteFAERS: 11US FAERS
40Feeling abnormalFAERS: 11US FAERS
41PainFAERS: 11US FAERS
42Prescribed overdoseFAERS: 11US FAERS
43SinusitisFAERS: 11US FAERS
44Wrong technique in product usage processFAERS: 11US FAERS
45AstheniaFAERS: 10US FAERS
46AnxietyFAERS: 9US FAERS
47ArthralgiaFAERS: 9US FAERS
48ConstipationFAERS: 9US FAERS
49Drug dose omissionFAERS: 9US FAERS
50NervousnessFAERS: 9US FAERS
51Product storage errorFAERS: 9US FAERS
52VomitingFAERS: 9US FAERS
53WheezingFAERS: 9US FAERS
54Accidental overdoseFAERS: 8US FAERS
55Blood glucose increasedFAERS: 8US FAERS
56DysgeusiaFAERS: 8US FAERS
57DysuriaFAERS: 8US FAERS
58Extra dose administeredFAERS: 8US FAERS
59Oral painFAERS: 8US FAERS
60Product quality issueFAERS: 8US FAERS
61UrticariaFAERS: 8US FAERS
62AlopeciaFAERS: 7US FAERS
63CataractFAERS: 7US FAERS
64ChillsFAERS: 7US FAERS
65GlaucomaFAERS: 7US FAERS
66Inability to afford medicationFAERS: 7US FAERS
67Intentional product misuseFAERS: 7US FAERS
68MyalgiaFAERS: 7US FAERS
69PalpitationsFAERS: 7US FAERS
70PruritusFAERS: 7US FAERS
71Respiratory FailureFAERS: 7US FAERS
72Choking sensationFAERS: 6US FAERS
73ErythemaFAERS: 6
Canada Vigilance: 1
Canada Vigilance
US FAERS
74Urinary tract infectionFAERS: 6US FAERS
75Atrial FibrillationFAERS: 5US FAERS
76BlindnessFAERS: 5US FAERS
77Device dispensing errorFAERS: 5US FAERS
78Diabetes MellitusFAERS: 5US FAERS
79DiplopiaFAERS: 5US FAERS
80FlatulenceFAERS: 5US FAERS
81InfectionFAERS: 5US FAERS
82Intentional dose omissionFAERS: 5US FAERS
83Product use issueFAERS: 5US FAERS
84Pulmonary painFAERS: 5US FAERS
85Therapeutic response unexpectedFAERS: 5US FAERS
86AphoniaFAERS: 4US FAERS
87Burning sensationFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
88DiscomfortFAERS: 4US FAERS
89DyspepsiaFAERS: 4US FAERS
90EpistaxisFAERS: 4US FAERS
91Feeling jitteryFAERS: 4US FAERS
92Gait inabilityFAERS: 4US FAERS
93Inappropriate schedule of product administrationFAERS: 4US FAERS
94Intercepted medication errorFAERS: 4US FAERS
95Lip swellingFAERS: 4US FAERS
96PneumothoraxFAERS: 4US FAERS
97Product prescribing errorFAERS: 4US FAERS
98Product residue presentFAERS: 4US FAERS
99Product taste abnormalFAERS: 4US FAERS
100RetchingFAERS: 4US FAERS
101Secretion dischargeFAERS: 4US FAERS
102Accidental exposure to productFAERS: 3US FAERS
103AgeusiaFAERS: 3US FAERS
104Ankle FractureFAERS: 3US FAERS
105Blood potassium decreasedFAERS: 3US FAERS
106BronchospasmFAERS: 3US FAERS
107Coating in mouthFAERS: 3US FAERS
108Drug prescribing errorFAERS: 3US FAERS
109Dry skinFAERS: 3US FAERS
110Eye irritationFAERS: 3US FAERS
111FlushingFAERS: 3US FAERS
112Foreign body in respiratory tractFAERS: 3US FAERS
113HypotensionFAERS: 3US FAERS
114Intercepted drug dispensing errorFAERS: 3US FAERS
115Joint swellingFAERS: 3US FAERS
116NeuralgiaFAERS: 3US FAERS
117Pulmonary EmbolismFAERS: 3US FAERS
118Rash erythematousFAERS: 3US FAERS
119Respiratory tract congestionFAERS: 3US FAERS
120SepsisFAERS: 3US FAERS
121SomnolenceFAERS: 3US FAERS
122StomatitisFAERS: 3US FAERS
123SyncopeFAERS: 3US FAERS
124TachycardiaFAERS: 3US FAERS
125Tongue blisteringFAERS: 3US FAERS
126ToothacheFAERS: 3US FAERS
127Urinary IncontinenceFAERS: 3US FAERS
128Abdominal PainFAERS: 2US FAERS
129Acute myocardial infarctionFAERS: 2US FAERS
130AmnesiaFAERS: 2US FAERS
131Angina PectorisFAERS: 2US FAERS
132AnosmiaFAERS: 2US FAERS
133Bladder spasmFAERS: 2US FAERS
134Blood glucose decreasedFAERS: 2US FAERS
135BronchiectasisFAERS: 2US FAERS
136BronchitisFAERS: 2US FAERS
137Cardiac FlutterFAERS: 2US FAERS
138Cataract operationFAERS: 2US FAERS
139CheilitisFAERS: 2US FAERS
140CystitisFAERS: 2US FAERS
141DementiaFAERS: 2US FAERS
142Device malfunctionFAERS: 2US FAERS
143Expired product administeredFAERS: 2US FAERS
144Feeling ColdFAERS: 2US FAERS
145FractureFAERS: 2US FAERS
146Head discomfortFAERS: 2US FAERS
147Hospice CareFAERS: 2US FAERS
148HypersensitivityFAERS: 2US FAERS
149HypersomniaFAERS: 2US FAERS
150HypoxiaFAERS: 2US FAERS
151Inappropriate schedule of drug administrationFAERS: 2US FAERS
152Incorrect dose administeredFAERS: 2US FAERS
153Increased upper airway secretionFAERS: 2US FAERS
154Intentional product use issueFAERS: 2US FAERS
155LaryngitisFAERS: 2US FAERS
156LethargyFAERS: 2US FAERS
157Limb discomfortFAERS: 2US FAERS
158Loss of personal independence in daily activitiesFAERS: 2US FAERS
159Memory impairmentFAERS: 2US FAERS
160Middle insomniaFAERS: 2US FAERS
161Multiple allergiesFAERS: 2US FAERS
162Nonspecific reactionFAERS: 2US FAERS
163ObstructionFAERS: 2US FAERS
164Ocular discomfortFAERS: 2US FAERS
165Oropharyngeal candidiasisFAERS: 2US FAERS
166Oxygen saturation abnormalFAERS: 2US FAERS
167PapuleFAERS: 2US FAERS
168Pericardial effusionFAERS: 2US FAERS
169Prescription drug used without a prescriptionFAERS: 2US FAERS
170Product appearance confusionFAERS: 2US FAERS
171Product communication issueFAERS: 2US FAERS
172Pulmonary FibrosisFAERS: 2US FAERS
173Pulmonary congestionFAERS: 2US FAERS
174Respiratory tract irritationFAERS: 2US FAERS
175SneezingFAERS: 2US FAERS
176Therapeutic product effect incompleteFAERS: 2US FAERS
177Therapy changeFAERS: 2US FAERS
178Throat clearingFAERS: 2US FAERS
179ThrombosisFAERS: 2US FAERS
180Tooth ExtractionFAERS: 2US FAERS
181VertigoFAERS: 2US FAERS
182Walking aid userFAERS: 2US FAERS
183Weight decreasedFAERS: 2US FAERS
184Abdominal discomfortFAERS: 1US FAERS
185Action TremorFAERS: 1US FAERS
186Acute Coronary SyndromeFAERS: 1US FAERS
187Acute respiratory failureFAERS: 1US FAERS
188AgitationFAERS: 1US FAERS
189Allergy to animalFAERS: 1US FAERS
190AmputationFAERS: 1US FAERS
191Anal fungal infectionFAERS: 1US FAERS
192AneurysmFAERS: 1US FAERS
193AngioedemaFAERS: 1US FAERS
194Anorectal discomfortFAERS: 1US FAERS
195AphasiaFAERS: 1US FAERS
196Apparent deathFAERS: 1US FAERS
197ArthropathyFAERS: 1US FAERS
198AsbestosisFAERS: 1US FAERS
199AtelectasisFAERS: 1US FAERS
200Back disorderFAERS: 1US FAERS
201Bladder discomfortFAERS: 1US FAERS
202Bladder painFAERS: 1US FAERS
203BlepharospasmFAERS: 1US FAERS
204Blood magnesium decreasedFAERS: 1US FAERS
205Blood potassium increasedFAERS: 1US FAERS
206Blood sodium decreasedFAERS: 1US FAERS
207Blood urine presentFAERS: 1US FAERS
208Bone lesionFAERS: 1US FAERS
209Borderline glaucomaFAERS: 1US FAERS
210BradycardiaFAERS: 1US FAERS
211Carbon dioxide increasedFAERS: 1US FAERS
212CellulitisFAERS: 1US FAERS
213Cerebral disorderFAERS: 1US FAERS
214CholelithiasisFAERS: 1US FAERS
215ChromaturiaFAERS: 1US FAERS
216Circumstance or information capable of leading to device use errorFAERS: 1US FAERS
217Critical IllnessFAERS: 1US FAERS
218DeliriumFAERS: 1US FAERS
219Dependence on oxygen therapyFAERS: 1US FAERS
220Depressed Level of ConsciousnessFAERS: 1US FAERS
221Device difficult to useFAERS: 1US FAERS
222Device related infectionFAERS: 1US FAERS
223Diabetic ulcerFAERS: 1US FAERS
224Diaphragmatic pacemaker insertionFAERS: 1US FAERS
225Disease recurrenceFAERS: 1US FAERS
226DisorientationFAERS: 1US FAERS
227DiverticulitisFAERS: 1US FAERS
228Drug DependenceFAERS: 1US FAERS
229Drug abuserFAERS: 1US FAERS
230Drug administration errorFAERS: 1US FAERS
231Drug effect delayedFAERS: 1US FAERS
232Drug effective for unapproved indicationFAERS: 1US FAERS
233Drug ineffective for unapproved indicationFAERS: 1US FAERS
234EczemaFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
235EructationFAERS: 1US FAERS
236ExophthalmosFAERS: 1US FAERS
237Exposure via ingestionFAERS: 1US FAERS
238Exposure via skin contactFAERS: 1US FAERS
239Expulsion of medicationFAERS: 1US FAERS
240Eye excisionFAERS: 1US FAERS
241Facial PainFAERS: 1US FAERS
242Food AllergyFAERS: 1US FAERS
243GangreneFAERS: 1US FAERS
244Gastrointestinal PainFAERS: 1US FAERS
245Gastrointestinal carcinomaFAERS: 1US FAERS
246General physical health deteriorationFAERS: 1US FAERS
247General symptomFAERS: 1US FAERS
248Gingival discomfortFAERS: 1US FAERS
249Hearing disabilityFAERS: 1US FAERS
250HemiplegiaFAERS: 1US FAERS
251Hepatitis CFAERS: 1US FAERS
252Hip surgeryFAERS: 1US FAERS
253HyperventilationFAERS: 1US FAERS
254HypothyroidismFAERS: 1US FAERS
255Immune thrombocytopenic purpuraFAERS: 1US FAERS
256Impaired work abilityFAERS: 1US FAERS
257Increased viscosity of bronchial secretionFAERS: 1US FAERS
258InflammationFAERS: 1US FAERS
259Initial insomniaFAERS: 1US FAERS
260Inspiratory capacity decreasedFAERS: 1US FAERS
261Intercepted product dispensing errorFAERS: 1US FAERS
262Intestinal PerforationFAERS: 1US FAERS
263Intracranial AneurysmFAERS: 1US FAERS
264Joint injuryFAERS: 1US FAERS
265Limb operationFAERS: 1US FAERS
266Lower respiratory tract congestionFAERS: 1US FAERS
267Lower respiratory tract infection bacterialFAERS: 1US FAERS
268Lower respiratory tract infection fungalFAERS: 1US FAERS
269Lung AbscessFAERS: 1US FAERS
270Lung consolidationFAERS: 1US FAERS
271Macular degenerationFAERS: 1US FAERS
272Medical device discomfortFAERS: 1US FAERS
273Medical device implantationFAERS: 1US FAERS
274Medical device painFAERS: 1US FAERS
275Medication residue presentFAERS: 1US FAERS
276MenorrhagiaFAERS: 1US FAERS
277Muscle strainFAERS: 1US FAERS
278Musculoskeletal discomfortFAERS: 1US FAERS
279Musculoskeletal stiffnessFAERS: 1US FAERS
280MydriasisFAERS: 1US FAERS
281NarcolepsyFAERS: 1US FAERS
282Nasal decongestion therapyFAERS: 1US FAERS
283Nasal mucosal erosionFAERS: 1US FAERS
284Night sweatsFAERS: 1US FAERS
285NocturiaFAERS: 1US FAERS
286ObesityFAERS: 1US FAERS
287OnychomycosisFAERS: 1US FAERS
288Oral fungal infectionFAERS: 1US FAERS
289Oral mucosal eruptionFAERS: 1US FAERS
290Oropharyngeal blisteringFAERS: 1US FAERS
291Oropharyngeal discomfortFAERS: 1US FAERS
292Painful ejaculationFAERS: 1US FAERS
293Pancreatic carcinomaFAERS: 1US FAERS
294PemphigusFAERS: 1US FAERS
295PericarditisFAERS: 1US FAERS
296PhotophobiaFAERS: 1US FAERS
297PneumonectomyFAERS: 1US FAERS
298PresyncopeFAERS: 1US FAERS
299Product availability issueFAERS: 1US FAERS
300Product design issueFAERS: 1US FAERS
301Product dispensing issueFAERS: 1US FAERS
302Product label issueFAERS: 1US FAERS
303Product name confusionFAERS: 1US FAERS
304Product packaging issueFAERS: 1US FAERS
305Product substitution issueFAERS: 1US FAERS
306Product used for unknown indicationFAERS: 1US FAERS
307Pulmonary function test decreasedFAERS: 1US FAERS
308Rehabilitation therapyFAERS: 1US FAERS
309Renal painFAERS: 1US FAERS
310Respiratory arrestFAERS: 1US FAERS
311Rheumatoid ArthritisFAERS: 1US FAERS
312Septic ShockFAERS: 1US FAERS
313ShockFAERS: 1US FAERS
314Skin discomfortFAERS: 1US FAERS
315Skin lacerationFAERS: 1US FAERS
316Skin lesionFAERS: 1US FAERS
317Spinal column injuryFAERS: 1US FAERS
318Squamous cell carcinomaFAERS: 1US FAERS
319Strangulated herniaFAERS: 1US FAERS
320Superficial vein prominenceFAERS: 1US FAERS
321SwellingFAERS: 1US FAERS
322Teeth brittleFAERS: 1US FAERS
323Temporal ArteritisFAERS: 1US FAERS
324TensionFAERS: 1US FAERS
325Terminal stateFAERS: 1US FAERS
326Therapeutic procedureFAERS: 1US FAERS
327Therapeutic product effect delayedFAERS: 1US FAERS
328Throat cancerFAERS: 1US FAERS
329TinnitusFAERS: 1US FAERS
330Tongue eruptionFAERS: 1US FAERS
331Urinary hesitationFAERS: 1US FAERS
332Urine flow decreasedFAERS: 1US FAERS
333Vocal Cord ParalysisFAERS: 1US FAERS
334Vulvovaginal mycotic infectionFAERS: 1US FAERS
335White blood cell count decreasedFAERS: 1US FAERS
336diagnostic procedureFAERS: 1US FAERS
337intensive careFAERS: 1US FAERS
338Lichen PlanusCanada Vigilance: 1Canada Vigilance
339PsoriasisCanada Vigilance: 1Canada Vigilance
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