MetaADEDB 2.0 @ LMMD
Enalaprilat
(LZFZMUMEGBBDTC-QEJZJMRPSA-N)
Structure
SMILES
OC(=O)[C@@H](N[C@H](C(=O)N1CCC[C@H]1C(=O)O)C)CCc1ccccc1
Type(s)
Approved
Molecular Formula:
C18H24N2O5
Molecular Weight:
348.394
Log P:
1.4549
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
3
TPSA:
106.94
CAS Number(s):
76420-72-9
Synonym(s)
1.
Enalaprilat
2.
Enalaprilic Acid
3.
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate
4.
Enalaprilat Anhydrous
5.
Enalaprilat Citrate, Anhydrous
6.
Enalaprilat Dihydrate
7.
Enalaprilat, (R)-Isomer, Anhydrous
8.
MK-422
9.
Pres iv
10.
Vasotec
11.
Xanef
12.
MK 422
13.
MK422
External Link(s)
MeSHD015773
PubChem Compound5462501
BindingDB50367254
ChEBI4786
CHEMBLCHEMBL577
DrugBankDB09477
DrugCentral1006
IUPHAR/BPS Guide to PHARMACOLOGY6332
KEGGcpd:C11720
Therapeutic Target DatabaseD0N5HJ
ZINC3812851
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AngioedemaFAERS: 4OFFSIDES
US FAERS
2ErythemaFAERS: 4US FAERS
3DizzinessFAERS: 2US FAERS
4VomitingFAERS: 2US FAERS
5Acute respiratory failureFAERS: 1US FAERS
6ArthralgiaFAERS: 1US FAERS
7AstheniaFAERS: 1US FAERS
8Blood pressure fluctuationFAERS: 1US FAERS
9BradycardiaFAERS: 111004045CTD
US FAERS
10Cardiac ArrestFAERS: 1US FAERS
11HypotensionFAERS: 1

View details

CTD
US FAERS
12LymphadenopathyFAERS: 1US FAERS
13NauseaFAERS: 1US FAERS
14Neck PainFAERS: 1US FAERS
15Nitritoid reactionFAERS: 1US FAERS
16SomnolenceFAERS: 1US FAERS
17SwellingFAERS: 1US FAERS
18TachycardiaFAERS: 111004045CTD
US FAERS
19Abdominal AbscessOFFSIDES
20AcidosisOFFSIDES
21Alanine Aminotransferase IncreasedOFFSIDES
22AnoxiaOFFSIDES
23Antiviral drug level above therapeuticOFFSIDES
24AtaxiaOFFSIDES
25Basal ganglion degenerationOFFSIDES
26Blood GlucoseOFFSIDES
27Blood creatine phosphokinase MB increasedOFFSIDES
28Blood creatinine increasedOFFSIDES
29Blood glucose decreasedOFFSIDES
30Blood urea increasedOFFSIDES
31Bone marrow depressionOFFSIDES
32Brain natriuretic peptide increasedOFFSIDES
33Burn debridementOFFSIDES
34Candida endophthalmitisOFFSIDES
35Cardiomegaly24342267CTD
36Cardiomyopathies9181721CTD
37Catheter related complicationOFFSIDES
38Catheter related infectionOFFSIDES
39Chronic ulcerative colitisOFFSIDES
40Circumstance or information capable of leading to medication errorOFFSIDES
41Creatinine renal clearance decreasedOFFSIDES
42Cytolytic hepatitisOFFSIDES
43DemyelinationOFFSIDES
44Diabetic FootOFFSIDES
45Diabetic foot infectionOFFSIDES
46DiarrheaOFFSIDES
47Disease recurrenceOFFSIDES
48DrowsinessOFFSIDES
49EmbolismOFFSIDES
50Erythema MultiformeOFFSIDES
51Escherichia infectionOFFSIDES
52ExophthalmosOFFSIDES
53FolliculitisOFFSIDES
54Gamma-Glutamyltransferase IncreasedOFFSIDES
55Gastrointestinal inflammationOFFSIDES
56General physical health deteriorationOFFSIDES
57GlobulinuriaOFFSIDES
58HepatitisOFFSIDES
59HepatosplenomegalyOFFSIDES
60Hyperglycemia28266800CTD
61Injection site burningOFFSIDES
62Intention tremorOFFSIDES
63Kidney FailureOFFSIDES
64LethargyOFFSIDES
65Leukopenia neonatalOFFSIDES
66LipaseOFFSIDES
67Listeria encephalitisOFFSIDES
68Long QT Syndrome23834779CTD
69Lung consolidationOFFSIDES
70Malignant HypertensionOFFSIDES
71Malignant tumour excisionOFFSIDES
72Motor retardationOFFSIDES
73Muscle hypertrophyOFFSIDES
74Muscular DystrophyOFFSIDES
75Mycobacterium chelonei infectionOFFSIDES
76MyelitisOFFSIDES
77MyelodysplasiaOFFSIDES
78Nephrotic SyndromeOFFSIDES
79OliguriaOFFSIDES
80PCO2 decreasedOFFSIDES
81PO2 decreasedOFFSIDES
82Peridiverticular abscessOFFSIDES
83PolymyositisOFFSIDES
84PolyuriaOFFSIDES
85Prescribed overdoseOFFSIDES
86Pulmonary arterial hypertensionOFFSIDES
87Reticulocyte count decreasedOFFSIDES
88Therapy non-responderOFFSIDES
89Transaminases increasedOFFSIDES
90Troponin TOFFSIDES
91Vascular Diseases1646895CTD
92Vitreous DetachmentOFFSIDES
93effusionOFFSIDES
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