Amikacin
(FXKSEJFHKVNEFI-GCZBSULCSA-N)
Structure
- SMILES
- OS(=O)(=O)O.OS(=O)(=O)O.NCC[C@@H](C(=O)N[C@@H]1C[C@H](N)[C@H]([C@@H]([C@H]1O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)N)O)O)O[C@H]1O[C@H](CN)[C@H]([C@@H]([C@H]1O)O)O)O
- Molecular Formula:
- C22H47N5O21S2
- Molecular Weight:
- 781.759
- Log P:
- -4.3761
- Hydrogen Bond Acceptor:
- 26
- Hydrogen Bond Donor:
- 17
- TPSA:
- 497.9
- CAS Number(s):
- 39831-55-5
Synonym(s)
1.
Amikacin
2.
A.M.K
3.
Amikacin Sulfate
4.
Amikacina Medical
5.
Amikacina Normon
6.
Amikafur
7.
Amikalem
8.
Amikason's
9.
Amikayect
10.
Amikin
11.
Amiklin
12.
Amukin
13.
BB-K 8
14.
BB-K8
15.
Biclin
16.
Biklin
17.
Gamikal
18.
Kanbine
19.
Oprad
20.
Yectamid
21.
BB K 8
22.
BB K8
23.
BBK 8
24.
BBK8
25.
Medical, Amikacina
26.
Normon, Amikacina
27.
Sulfate, Amikacin
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Tinnitus | FAERS: 3 | US FAERS | |
| 2 | Acute kidney injury | FAERS: 2 | US FAERS | |
| 3 | Deafness | FAERS: 2 | US FAERS | |
| 4 | General physical health deterioration | FAERS: 2 | US FAERS | |
| 5 | Medication Error | FAERS: 2 | US FAERS | |
| 6 | Accidental exposure to product by child | FAERS: 1 | US FAERS | |
| 7 | Accidental overdose | FAERS: 1 | US FAERS | |
| 8 | Acute respiratory failure | FAERS: 1 | US FAERS | |
| 9 | Altered state of consciousness | FAERS: 1 | US FAERS | |
| 10 | Amaurosis | FAERS: 1 | US FAERS | |
| 11 | Anuria | FAERS: 1 | US FAERS | |
| 12 | Back Pain | FAERS: 1 | US FAERS | |
| 13 | Bronchopulmonary Aspergillosis | FAERS: 1 | US FAERS | |
| 14 | Burning sensation | FAERS: 1 | US FAERS | |
| 15 | Cardiac Arrest | FAERS: 1 | US FAERS | |
| 16 | Dehydration | FAERS: 1 | US FAERS | |
| 17 | Dysarthria | FAERS: 1 | US FAERS | |
| 18 | Ear discomfort | FAERS: 1 | US FAERS | |
| 19 | Exophthalmos | FAERS: 1 | US FAERS | |
| 20 | Febrile Neutropenia | FAERS: 1 | US FAERS | |
| 21 | Headache | FAERS: 1 | US FAERS | |
| 22 | Hemiparesis | FAERS: 1 | US FAERS | |
| 23 | Hepatosplenic candidiasis | FAERS: 1 | US FAERS | |
| 24 | Incorrect route of drug administration | FAERS: 1 | US FAERS | |
| 25 | Injection site phlebitis | FAERS: 1 | US FAERS | |
| 26 | Leukocytoclastic vasculitis | FAERS: 1 | US FAERS | |
| 27 | Nausea | FAERS: 1 | US FAERS | |
| 28 | Neutropenic colitis | FAERS: 1 | US FAERS | |
| 29 | Peritonsillar Abscess | FAERS: 1 | US FAERS | |
| 30 | Pleuritic pain | FAERS: 1 | US FAERS | |
| 31 | Pneumonia | FAERS: 1 | US FAERS | |
| 32 | Polyuria | FAERS: 1 | US FAERS | |
| 33 | Respiratory arrest | FAERS: 1 | US FAERS | |
| 34 | Respiratory tract irritation | FAERS: 1 | US FAERS | |
| 35 | Scedosporium infection | FAERS: 1 | US FAERS | |
| 36 | Sinusitis | FAERS: 1 | US FAERS | |
| 37 | Somnolence | FAERS: 1 | US FAERS | |
| 38 | Stevens-Johnson Syndrome | FAERS: 1 | US FAERS | |
| 39 | Tetany | FAERS: 1 | US FAERS | |
| 40 | Thrombocytopenia | FAERS: 1 | US FAERS | |
| 41 | Tonsillitis | FAERS: 1 | US FAERS | |
| 42 | Vasculitis | FAERS: 1 | US FAERS | |
| 43 | Vomiting | FAERS: 1 | US FAERS | |
| 44 | Blood creatinine increased | Canada Vigilance: 2 | Canada Vigilance | |
| 45 | Drug level increased | Canada Vigilance: 1 | Canada Vigilance | |
| 46 | Ototoxicity | Canada Vigilance: 1 | Canada Vigilance |
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