tafluprost
(WSNODXPBBALQOF-VEJSHDCNSA-N)
Structure
- SMILES
- CC(OC(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@H]([C@@H]1/C=C/C(COc1ccccc1)(F)F)O)C
- Type(s)
- Approved
- ATC code(s)
- S01EE05
- Molecular Formula:
- C25H34F2O5
- Molecular Weight:
- 452.531
- Log P:
- 4.6830
- Hydrogen Bond Acceptor:
- 5
- Hydrogen Bond Donor:
- 2
- TPSA:
- 75.99
- CAS Number(s):
- 209860-87-7
Synonym(s)
1.
tafluprost
2.
1-methylethyl (5Z)-7-((1R,2R, 3R,5S)-2-((1E)-3,3-difluoro-4-phenoxy -1-butenyl)-3,5-dihydroxycyclopentyl)-5-heptenoate
3.
AFP-168
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Eye irritation | FAERS: 125 | SIDER US FAERS | |
| 2 | Eye pain | FAERS: 62 | SIDER US FAERS | |
| 3 | Headache | FAERS: 49 | SIDER US FAERS | |
| 4 | Drug ineffective | FAERS: 43 | US FAERS | |
| 5 | No adverse event | FAERS: 33 | US FAERS | |
| 6 | Photophobia | FAERS: 19 | SIDER US FAERS | |
| 7 | Dizziness | FAERS: 18 | US FAERS | |
| 8 | Pain | FAERS: 16 | US FAERS | |
| 9 | Arthralgia | FAERS: 15 | US FAERS | |
| 10 | Hypersensitivity | FAERS: 15 | US FAERS | |
| 11 | Incorrect storage of drug | FAERS: 15 | US FAERS | |
| 12 | Nasopharyngitis | FAERS: 14 | SIDER US FAERS | |
| 13 | Urinary tract infection | FAERS: 13 | SIDER US FAERS | |
| 14 | Overdose | FAERS: 12 | US FAERS | |
| 15 | Incorrect product storage | FAERS: 10 | US FAERS | |
| 16 | Foreign body sensation in eyes | FAERS: 9 | SIDER US FAERS | |
| 17 | Pruritus | FAERS: 9 | SIDER US FAERS | |
| 18 | Visual Impairment | FAERS: 9 | US FAERS | |
| 19 | Alopecia | FAERS: 8 | US FAERS | |
| 20 | Drug dose omission | FAERS: 8 | US FAERS | |
| 21 | Eye inflammation | FAERS: 8 | US FAERS | |
| 22 | Nausea | FAERS: 8 | US FAERS | |
| 23 | Blepharitis | FAERS: 7 | US FAERS | |
| 24 | Blindness | FAERS: 7 | US FAERS | |
| 25 | Burning sensation | FAERS: 7 | US FAERS | |
| 26 | Dysgeusia | FAERS: 7 | US FAERS | |
| 27 | Erythema | FAERS: 7 | US FAERS | |
| 28 | Multiple use of single-use product | FAERS: 7 | US FAERS | |
| 29 | Product quality issue | FAERS: 7 | US FAERS | |
| 30 | Corneal erosion | FAERS: 6 | US FAERS | |
| 31 | Eyelid irritation | FAERS: 6 | US FAERS | |
| 32 | Malaise | FAERS: 6 | US FAERS | |
| 33 | Ocular discomfort | FAERS: 6 | US FAERS | |
| 34 | Adverse event | FAERS: 5 | US FAERS | |
| 35 | Cataract operation | FAERS: 5 | US FAERS | |
| 36 | Eyelids pruritus | FAERS: 5 | US FAERS | |
| 37 | Urticaria | FAERS: 5 | US FAERS | |
| 38 | Chest Pain | FAERS: 4 | US FAERS | |
| 39 | Conjunctivitis | FAERS: 4 | US FAERS | |
| 40 | Expired product administered | FAERS: 4 | US FAERS | |
| 41 | Eye Burns | FAERS: 4 | US FAERS | |
| 42 | Eyelid margin crusting | FAERS: 4 | US FAERS | |
| 43 | Eyelid skin dryness | FAERS: 4 | US FAERS | |
| 44 | Growth of eyelashes | FAERS: 4 | SIDER US FAERS | |
| 45 | Myalgia | FAERS: 4 | US FAERS | |
| 46 | Retinal Detachment | FAERS: 4 | US FAERS | |
| 47 | Tinnitus | FAERS: 4 | US FAERS | |
| 48 | Asthenopia | FAERS: 3 | US FAERS | |
| 49 | Back Pain | FAERS: 3 | US FAERS | |
| 50 | Cataract | FAERS: 3 | SIDER US FAERS | |
| 51 | Cerebral Infarction | FAERS: 3 | US FAERS | |
| 52 | Cerebrovascular accident | FAERS: 3 | US FAERS | |
| 53 | Discomfort | FAERS: 3 | US FAERS | |
| 54 | Dysphonia | FAERS: 3 | US FAERS | |
| 55 | Fatigue | FAERS: 3 | US FAERS | |
| 56 | Optic Neuritis | FAERS: 3 | US FAERS | |
| 57 | Oropharyngeal pain | FAERS: 3 | US FAERS | |
| 58 | Poor quality drug administered | FAERS: 3 | US FAERS | |
| 59 | Somnolence | FAERS: 3 | US FAERS | |
| 60 | Swelling | FAERS: 3 | US FAERS | |
| 61 | Abdominal discomfort | FAERS: 2 | US FAERS | |
| 62 | Ageusia | FAERS: 2 | US FAERS | |
| 63 | Amaurosis Fugax | FAERS: 2 | US FAERS | |
| 64 | Anal Fistula | FAERS: 2 | US FAERS | |
| 65 | Ankle Fracture | FAERS: 2 | US FAERS | |
| 66 | Apparent death | FAERS: 2 | US FAERS | |
| 67 | Asthma | FAERS: 2 | SIDER US FAERS | |
| 68 | Chloropsia | FAERS: 2 | US FAERS | |
| 69 | Dark circles under eyes | FAERS: 2 | US FAERS | |
| 70 | Dry skin | FAERS: 2 | US FAERS | |
| 71 | Dyspepsia | FAERS: 2 | US FAERS | |
| 72 | Epistaxis | FAERS: 2 | US FAERS | |
| 73 | Eye Infection | FAERS: 2 | US FAERS | |
| 74 | Glaucoma | FAERS: 2 | US FAERS | |
| 75 | Hysterectomy | FAERS: 2 | US FAERS | |
| 76 | Incorrect dose administered | FAERS: 2 | US FAERS | |
| 77 | Instillation site exfoliation | FAERS: 2 | US FAERS | |
| 78 | Intercepted drug dispensing error | FAERS: 2 | US FAERS | |
| 79 | Intraocular pressure fluctuation | FAERS: 2 | US FAERS | |
| 80 | Lip swelling | FAERS: 2 | US FAERS | |
| 81 | Macular fibrosis | FAERS: 2 | US FAERS | |
| 82 | Metastasis | FAERS: 2 | US FAERS | |
| 83 | Myocardial Infarction | FAERS: 2 | US FAERS | |
| 84 | Product storage error | FAERS: 2 | US FAERS | |
| 85 | Skin irritation | FAERS: 2 | US FAERS | |
| 86 | Swelling of eyelid | FAERS: 2 | US FAERS | |
| 87 | Throat irritation | FAERS: 2 | US FAERS | |
| 88 | Uveitis | FAERS: 2 | SIDER US FAERS | |
| 89 | Wheezing | FAERS: 2 | US FAERS | |
| 90 | Abdominal Pain | FAERS: 1 | US FAERS | |
| 91 | Accidental overdose | FAERS: 1 | US FAERS | |
| 92 | Activities of daily living impaired | FAERS: 1 | US FAERS | |
| 93 | Angina Pectoris | FAERS: 1 | US FAERS | |
| 94 | Anosmia | FAERS: 1 | US FAERS | |
| 95 | Anterior chamber inflammation | FAERS: 1 | US FAERS | |
| 96 | Aphonia | FAERS: 1 | US FAERS | |
| 97 | Asphyxia | FAERS: 1 | US FAERS | |
| 98 | Asthenia | FAERS: 1 | US FAERS | |
| 99 | Benign Prostatic Hyperplasia | FAERS: 1 | US FAERS | |
| 100 | Blood glucose increased | FAERS: 1 | US FAERS | |
| 101 | Blood potassium decreased | FAERS: 1 | US FAERS | |
| 102 | Cellulitis | FAERS: 1 | US FAERS | |
| 103 | Chest discomfort | FAERS: 1 | US FAERS | |
| 104 | Chills | FAERS: 1 | US FAERS | |
| 105 | Choking | FAERS: 1 | US FAERS | |
| 106 | Cholelithiasis | FAERS: 1 | US FAERS | |
| 107 | Chromatopsia | FAERS: 1 | US FAERS | |
| 108 | Chromaturia | FAERS: 1 | US FAERS | |
| 109 | Circumstance or information capable of leading to medication error | FAERS: 1 | US FAERS | |
| 110 | Conjunctival laceration | FAERS: 1 | US FAERS | |
| 111 | Contact lens intolerance | FAERS: 1 | US FAERS | |
| 112 | Corneal Opacity | FAERS: 1 | US FAERS | |
| 113 | Corneal degeneration | FAERS: 1 | US FAERS | |
| 114 | Cystitis | FAERS: 1 | US FAERS | |
| 115 | Deafness | FAERS: 1 | US FAERS | |
| 116 | Deep Vein Thrombosis | FAERS: 1 | US FAERS | |
| 117 | Depressed mood | FAERS: 1 | US FAERS | |
| 118 | Diet refusal | FAERS: 1 | US FAERS | |
| 119 | Diplopia | FAERS: 1 | US FAERS | |
| 120 | Documented hypersensitivity to administered product | FAERS: 1 | US FAERS | |
| 121 | Drug administration error | FAERS: 1 | US FAERS | |
| 122 | Drug dispensing error | FAERS: 1 | US FAERS | |
| 123 | Drug prescribing error | FAERS: 1 | US FAERS | |
| 124 | Enophthalmos | FAERS: 1 | US FAERS | |
| 125 | Eructation | FAERS: 1 | US FAERS | |
| 126 | Excessive eye blinking | FAERS: 1 | US FAERS | |
| 127 | Exophthalmos | FAERS: 1 | US FAERS | |
| 128 | Eye allergy | FAERS: 1 | US FAERS | |
| 129 | Eyelash hyperpigmentation | FAERS: 1 | SIDER US FAERS | |
| 130 | Eyelash thickening | FAERS: 1 | SIDER US FAERS | |
| 131 | Eyelid infection | FAERS: 1 | US FAERS | |
| 132 | Eyelid rash | FAERS: 1 | US FAERS | |
| 133 | Facial Pain | FAERS: 1 | US FAERS | |
| 134 | Gastritis | FAERS: 1 | US FAERS | |
| 135 | Gastroenteritis | FAERS: 1 | US FAERS | |
| 136 | Gout | FAERS: 1 | US FAERS | |
| 137 | Hypotension | FAERS: 1 | US FAERS | |
| 138 | Impaired driving ability | FAERS: 1 | US FAERS | |
| 139 | Incorrect product dosage form administered | FAERS: 1 | US FAERS | |
| 140 | Instillation site foreign body sensation | FAERS: 1 | US FAERS | |
| 141 | Iris hyperpigmentation | FAERS: 1 | SIDER US FAERS | |
| 142 | Iritis | FAERS: 1 | SIDER US FAERS | |
| 143 | Irregular breathing | FAERS: 1 | US FAERS | |
| 144 | Joint swelling | FAERS: 1 | US FAERS | |
| 145 | Lid sulcus deepened | FAERS: 1 | US FAERS | |
| 146 | Lymphadenopathy | FAERS: 1 | US FAERS | |
| 147 | Lymphoma | FAERS: 1 | US FAERS | |
| 148 | Malignant neoplasm progression | FAERS: 1 | US FAERS | |
| 149 | Memory impairment | FAERS: 1 | US FAERS | |
| 150 | Musculoskeletal chest pain | FAERS: 1 | US FAERS | |
| 151 | Musculoskeletal stiffness | FAERS: 1 | US FAERS | |
| 152 | Myasthenia Gravis | FAERS: 1 | US FAERS | |
| 153 | Mydriasis | FAERS: 1 | US FAERS | |
| 154 | Ocular Rosacea | FAERS: 1 | US FAERS | |
| 155 | Ocular icterus | FAERS: 1 | US FAERS | |
| 156 | Osteoporosis | FAERS: 1 | US FAERS | |
| 157 | Oxygen consumption decreased | FAERS: 1 | US FAERS | |
| 158 | Palpitations | FAERS: 1 | US FAERS | |
| 159 | Pancreatic carcinoma | FAERS: 1 | US FAERS | |
| 160 | Paranasal sinus discomfort | FAERS: 1 | US FAERS | |
| 161 | Periorbital swelling | FAERS: 1 | US FAERS | |
| 162 | Peripheral swelling | FAERS: 1 | US FAERS | |
| 163 | Pharyngeal swelling | FAERS: 1 | US FAERS | |
| 164 | Physical deconditioning | FAERS: 1 | US FAERS | |
| 165 | Posterior capsule rupture | FAERS: 1 | US FAERS | |
| 166 | Product container issue | FAERS: 1 | US FAERS | |
| 167 | Product dropper issue | FAERS: 1 | US FAERS | |
| 168 | Product label issue | FAERS: 1 | US FAERS | |
| 169 | Product packaging issue | FAERS: 1 | US FAERS | |
| 170 | Product substitution issue | FAERS: 1 | US FAERS | |
| 171 | Productive Cough | FAERS: 1 | US FAERS | |
| 172 | Punctate keratitis | FAERS: 1 | SIDER US FAERS | |
| 173 | Reaction to preservatives | FAERS: 1 | US FAERS | |
| 174 | Respiratory arrest | FAERS: 1 | US FAERS | |
| 175 | Retinal Vascular Disorder | FAERS: 1 | US FAERS | |
| 176 | Retinal pigment epithelial tear | FAERS: 1 | US FAERS | |
| 177 | Rhinitis | FAERS: 1 | SIDER US FAERS | |
| 178 | Sepsis | FAERS: 1 | US FAERS | |
| 179 | Spinal column injury | FAERS: 1 | US FAERS | |
| 180 | Stitch abscess | FAERS: 1 | US FAERS | |
| 181 | Sudden onset of sleep | FAERS: 1 | US FAERS | |
| 182 | Superficial injury of eye | FAERS: 1 | US FAERS | |
| 183 | Synovial Cyst | FAERS: 1 | US FAERS | |
| 184 | Tachyphylaxis | FAERS: 1 | US FAERS | |
| 185 | Thrombosis | FAERS: 1 | US FAERS | |
| 186 | Tooth Extraction | FAERS: 1 | US FAERS | |
| 187 | Traumatic fracture | FAERS: 1 | US FAERS | |
| 188 | Tremor | FAERS: 1 | US FAERS | |
| 189 | Unevaluable event | FAERS: 1 | US FAERS | |
| 190 | Urinary tract infection fungal | FAERS: 1 | US FAERS | |
| 191 | Uterine Prolapse | FAERS: 1 | US FAERS | |
| 192 | Vertigo | FAERS: 1 | US FAERS | |
| 193 | Viral upper respiratory tract infection | FAERS: 1 | US FAERS | |
| 194 | Vitreous floaters | FAERS: 1 | US FAERS | |
| 195 | Vulvovaginal dryness | FAERS: 1 | US FAERS | |
| 196 | Weight decreased | FAERS: 1 | US FAERS | |
| 197 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 198 | Wrong technique in drug usage process | FAERS: 1 | US FAERS | |
| 199 | Common Cold | SIDER | ||
| 200 | Endophthalmitis | SIDER | ||
| 201 | Exacerbation of asthma | SIDER | ||
| 202 | Eyelash darkening | SIDER | ||
| 203 | Ocular stinging | SIDER | ||
| 204 | nervous system disorder | SIDER |
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