Monocrotaline
(QVCMHGGNRFRMAD-XFGHUUIASA-N)
Structure
- SMILES
- O=C1O[C@@H]2CCN3[C@@H]2C(=CC3)COC(=O)[C@]([C@]([C@H]1C)(C)O)(C)O
- Molecular Formula:
- C16H23NO6
- Molecular Weight:
- 325.357
- Log P:
- -0.4547
- Hydrogen Bond Acceptor:
- 7
- Hydrogen Bond Donor:
- 2
- TPSA:
- 96.3
- CAS Number(s):
- 315-22-0
Synonym(s)
1.
Monocrotaline
2.
Monocrotaline Hydrochloride (13alpha,14alpha)-Isomer
3.
Monocrotaline, (all-xi)-Isomer
External Link(s)
| MeSH | D016686 |
| PubChem Compound | 9415 |
| ChEBI | 6980 |
| CHEMBL | CHEMBL521035 |
| KEGG | cpd:C10350 |
| Therapeutic Target Database | D0G6AB |
| ZINC | 53195720 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Ascites | 29908794 | CTD | |
| 2 | Cachexia | 18801959 | CTD | |
| 3 | Cardiomegaly | 18801959 21619414 | CTD | |
| 4 | Chemical and Drug Induced Liver Injury | CTD | ||
| 5 | Fetal Growth Retardation | 30825512 | CTD | |
| 6 | Fibrosis | 27870162 | CTD | |
| 7 | Heart failure | 19650993 | CTD | |
| 8 | Hemorrhage | 22407844 29908794 | CTD | |
| 9 | Hepatic Encephalopathy | 21224054 | CTD | |
| 10 | Hepatic Veno-Occlusive Disease | 19387321 29908794 31470032 | CTD | |
| 11 | Hypertrophy | 17575010 | CTD | |
| 12 | Kidney Diseases | 19761811 21327618 | CTD | |
| 13 | Liver neoplasms | 25058030 | CTD | |
| 14 | Massive Hepatic Necrosis | 21224054 22407844 | CTD | |
| 15 | Necrosis | 24418708 | CTD | |
| 16 | Vascular Diseases | 27870162 | CTD | |
| 17 | Ventricular Remodeling | 22146233 | CTD |
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