Folfox protocol
(YXTKHLHCVFUPPT-YYFJYKOTSA-N)
Structure
- SMILES
- OC(=O)C(=O)O.[CH2-][C@@H]1CCCC[C@H]1[CH2-].Fc1c[nH]c(=O)[nH]c1=O.O=CN1C(CNc2ccc(cc2)C(=O)N[C@H](C(=O)O)CCC(=O)O)CNc2c1c(=O)[nH]c(n2)N.[Pt+2]
- Molecular Formula:
- C34H42FN9O13Pt
- Molecular Weight:
- 998.826
- Log P:
- 1.9693
- Hydrogen Bond Acceptor:
- 19
- Hydrogen Bond Donor:
- 11
- TPSA:
- 360.16
- CAS Number(s):
- N/A
Synonym(s)
1.
Folfox protocol
2.
FOLFOX-4 protocol
3.
FOLFOX-6 protocol
4.
FOLFOX-7 protocol
5.
FOLFOX4 protocol
6.
Folfox regimen
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Aphasia | FAERS: 1 | US FAERS | |
| 2 | Ascites | FAERS: 1 | US FAERS | |
| 3 | Disease Progression | FAERS: 1 | US FAERS | |
| 4 | Nausea | FAERS: 1 | 19838030 | CTD US FAERS |
| 5 | Adenocarcinoma | 21110884 | CTD | |
| 6 | Anemia | 19838030 | CTD | |
| 7 | Anorexia | 19838030 | CTD | |
| 8 | Chemical and Drug Induced Liver Injury | 17565263 | CTD | |
| 9 | Chest Pain | 19203898 | CTD | |
| 10 | Colonic Neoplasms | 17851880 19414665 20460542 | CTD | |
| 11 | Colorectal Neoplasms | CTD | ||
| 12 | Diarrhea | 19838030 | CTD | |
| 13 | Fatigue | 19838030 | CTD | |
| 14 | Fatty Liver | 17805566 | CTD | |
| 15 | Feeding and Eating Disorders | 19920390 | CTD | |
| 16 | Hepatic Insufficiency | 20567921 | CTD | |
| 17 | Hepatic Veno-Occlusive Disease | 19019605 | CTD | |
| 18 | Hypokinesia | 19203898 | CTD | |
| 19 | Leukopenia | 19838030 | CTD | |
| 20 | Liver neoplasms | 17565263 | CTD | |
| 21 | Neoplasm Metastasis | 17565263 | CTD | |
| 22 | Neutropenia | 19838030 20819832 | CTD | |
| 23 | Pain | 19414665 | CTD | |
| 24 | Peripheral Nervous System Diseases | CTD | ||
| 25 | Phlebitis | 19011337 | CTD | |
| 26 | Rectal Neoplasms | 17825542 | CTD | |
| 27 | Sensation Disorders | 20332703 | CTD | |
| 28 | Stomach Neoplasms | 18505590 21110884 | CTD | |
| 29 | Thrombocytopenia | 19414665 19838030 | CTD | |
| 30 | Ventricular Dysfunction, Left | 19203898 | CTD | |
| 31 | Vomiting | 19838030 | CTD |
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