MetaADEDB 2.0 @ LMMD
Floxuridine
(ODKNJVUHOIMIIZ-RRKCRQDMSA-N)
Structure
SMILES
OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
Type(s)
Approved
ATC code(s)
L01BC09
Molecular Formula:
C9H11FN2O5
Molecular Weight:
246.192
Log P:
-1.6836
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
3
TPSA:
104.55
CAS Number(s):
50-91-9; 136353-77-0; 136353-81-6; 136353-85-0; 396726-50-4
Synonym(s)
1.
Floxuridine
External Link(s)
PubChem Compound5790
BindingDB50340678
ChEBI60761
CHEMBLCHEMBL917
DrugBankDB00322
DrugCentral1184
IUPHAR/BPS Guide to PHARMACOLOGY4801
KEGGcpd:C11736
dr:D04197
Therapeutic Target DatabaseD0TS1Z
D06EGK
ZINC3813010
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Blood erythropoietin increasedFAERS: 1US FAERS
2Cerebellar AtaxiaFAERS: 1US FAERS
3Diabetes mellitus inadequate controlFAERS: 1US FAERS
4Febrile NeutropeniaFAERS: 1US FAERS
5General physical health deteriorationFAERS: 1US FAERS
6InfectionFAERS: 1SIDER
US FAERS
7Mixed venous blood saturation decreasedFAERS: 1US FAERS
8NauseaFAERS: 16199474CTD
SIDER
US FAERS
9NeutropeniaFAERS: 1US FAERS
10Procedural complicationFAERS: 1US FAERS
11SepsisFAERS: 1US FAERS
12TachycardiaFAERS: 1US FAERS
13ThrombocytopeniaFAERS: 1SIDER
US FAERS
14Unresponsive to stimuliFAERS: 1US FAERS
15jaundiceFAERS: 12939001
11677951		CTD
US FAERS
16Abdominal Pain6199474CTD
SIDER
17Abscess1825358CTD
SIDER
18Acalculous CholecystitisSIDER
19Adenocarcinoma3157786CTD
20AgranulocytosisSIDER
21AlopeciaSIDER
22Anaphylactic shockSIDER
23AneurysmSIDER
24Angina PectorisSIDER
25Anorexia6199474CTD
SIDER
26Arterial Occlusive Diseases2522675
2848277		CTD
27Arterial aneurysmSIDER
28Arterial thrombosisSIDER
29AstheniaSIDER
30Ataxia2943526CTD
31Bile Duct Diseases2934836
2939001		CTD
32Biliary Tract Diseases8862076CTD
33Chemical and Drug Induced Liver Injury

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1387318
1829068
6199474
19093069
22166485
 		CTD
34Cholangitis, Sclerosing

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1825358
1829068
2521475
2521845
2848277
2933968
2937274
2939001
2949003
2951292
3160062
16633109
 		CTD
35Cholangitis3044469
3160063
11677951		CTD
36Cholecystitis

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2933968
2935378
2941626
3157786
6225318
 		CTD
SIDER
37Cholestasis2937274CTD
38Colonic Neoplasms2935680
2951292		CTD
39Colorectal Neoplasms2937274
2941626
15040806		CTD
40Common Bile Duct Diseases2935680CTD
41Confusion2943526CTD
42DermatitisSIDER
43Diarrhea6199474CTD
44DiscomfortSIDER
45DisorientationSIDER
46Dry skinSIDER
47Duodenal UlcerSIDER
48DuodenitisSIDER
49EmbolismSIDER
50EnteritisSIDER
51EpistaxisSIDER
52ErythemaSIDER
53Euphoric moodSIDER
54Fatigue6199474CTD
55Fatty Liver2138409CTD
56Feeling abnormalSIDER
57FibromyalgiaSIDER
58GastritisSIDER
59GastroenteritisSIDER
60Gastrointestinal Diseases1825358CTD
61Gastrointestinal Neoplasms1825358CTD
62Gastrointestinal PainSIDER
63GlossitisSIDER
64HeadacheSIDER
65Heart Diseases22166485CTD
66Hepatic Veno-Occlusive Disease2531719CTD
67Hepatic necrosisSIDER
68Hepatitis1825358CTD
69Hyperbilirubinemia2521845CTD
70HypersensitivitySIDER
71Jaundice, Obstructive2848277
2971425		CTD
72LacrimationSIDER
73LethargySIDER
74LeukopeniaSIDER
75Liver Cirrhosis2877311CTD
76Liver Failure2521475CTD
77Liver diseases2522675
2848277
8862076		CTD
78Liver neoplasms

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2521475
2526963
2848277
2933968
2935378
2943526
2943876
2949003
3160062
3160063
6199474
8862076
11677951
 		CTD
79Localized erythemaSIDER
80MalaiseSIDER
81Myoclonus2943526CTD
82Nail changesSIDER
83Neoplasm Metastasis

View details

2848277
2935378
2937274
2943876
2949003
3160063
8862076
 		CTD
84NystagmusSIDER
85Ocular Motility Disorders2943526CTD
86PancytopeniaSIDER
87PharyngitisSIDER
88PhotophobiaSIDER
89Renal Insufficiency22166485CTD
90Sigmoid Neoplasms2877311CTD
91Skin toxicitySIDER
92StomatitisSIDER
93ThrombophlebitisSIDER
94Vomiting6199474CTD
SIDER
95nervous system disorderSIDER
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