MetaADEDB 2.0 @ LMMD
naratriptan
(AMKVXSZCKVJAGH-UHFFFAOYSA-N)
Structure
SMILES
CNS(=O)(=O)CCc1ccc2c(c1)c(c[nH]2)C1CCN(CC1)C
Type(s)
Approved; Investigational
ATC code(s)
N02CC02
Molecular Formula:
C17H25N3O2S
Molecular Weight:
335.464
Log P:
3.4784
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
73.58
CAS Number(s):
121679-13-8
Synonym(s)
1.
naratriptan
2.
1H-indole-5-ethanesulfonamide, N-methyl-3-(1-methyl-4-piperidinyl)-, monohydrochloride
3.
Amerge
4.
Colatan
5.
GR 85548A
6.
N-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide
7.
N-methyl-3-(1-methyl-4-piperidyl)indole-5-ethanesulfonamide monohydrochloride
8.
Naramig
9.
naratriptan hydrochloride
External Link(s)
MeSHC106783
PubChem Compound4440
BindingDB50073682
ChEBI7478
CHEMBLCHEMBL1278
DrugBankDB00952
DrugCentral1884
IUPHAR/BPS Guide to PHARMACOLOGY45
KEGGdr:D08255
cpd:C07792
Therapeutic Target DatabaseD0T3KI
ZINC4076
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 17OFFSIDES
US FAERS
2Product substitution issueFAERS: 6US FAERS
3Drug DependenceFAERS: 4US FAERS
4Retinal Vein OcclusionFAERS: 4US FAERS
5Chest PainFAERS: 3OFFSIDES
US FAERS
6DizzinessFAERS: 210972634CTD
OFFSIDES
SIDER
US FAERS
7Drug abuseFAERS: 2US FAERS
8Electrocardiogram abnormalFAERS: 2SIDER
US FAERS
9Intentional drug misuseFAERS: 2US FAERS
10NauseaFAERS: 210972634CTD
OFFSIDES
SIDER
US FAERS
11No adverse eventFAERS: 2US FAERS
12OverdoseFAERS: 2US FAERS
13VomitingFAERS: 210972634CTD
SIDER
US FAERS
14Abdominal discomfortFAERS: 1OFFSIDES
SIDER
US FAERS
15Accidental drug intake by childFAERS: 1US FAERS
16Activities of daily living impairedFAERS: 1US FAERS
17Acute Coronary SyndromeFAERS: 119538745CTD
OFFSIDES
SIDER
US FAERS
18Angina PectorisFAERS: 1SIDER
US FAERS
19AnxietyFAERS: 1OFFSIDES
SIDER
US FAERS
20AsthmaFAERS: 1SIDER
US FAERS
21Blighted ovumFAERS: 1US FAERS
22Blood sodium decreasedFAERS: 1US FAERS
23Bronchial ObstructionFAERS: 1US FAERS
24BronchospasmFAERS: 1US FAERS
25Congenital HydrocephalusFAERS: 1US FAERS
26ConstipationFAERS: 1SIDER
US FAERS
27DiplopiaFAERS: 1OFFSIDES
US FAERS
28Drug exposure during pregnancyFAERS: 1US FAERS
29Drug screen positiveFAERS: 1OFFSIDES
US FAERS
30DystoniaFAERS: 1OFFSIDES
US FAERS
31ErythemaFAERS: 1SIDER
US FAERS
32Feeding disorder of infancy OR early childhoodFAERS: 1OFFSIDES
US FAERS
33FlushingFAERS: 1US FAERS
34HypersensitivityFAERS: 1SIDER
US FAERS
35Hypoaesthesia facialFAERS: 1US FAERS
36Incorrect product storageFAERS: 1US FAERS
37Limb injuryFAERS: 1US FAERS
38Maternal exposure during pregnancyFAERS: 1US FAERS
39Muscle tightnessFAERS: 1US FAERS
40PainFAERS: 1OFFSIDES
SIDER
US FAERS
41PalpitationsFAERS: 1SIDER
US FAERS
42PoisoningFAERS: 1US FAERS
43Product quality issueFAERS: 1US FAERS
44Reaction to excipientFAERS: 1US FAERS
45SyncopeFAERS: 1SIDER
US FAERS
46Therapeutic response changedFAERS: 1US FAERS
47treatment failureFAERS: 1US FAERS
48Abdominal PainOFFSIDES
49Abdominal adhesionsOFFSIDES
50AbuseOFFSIDES
51Accidental overdoseOFFSIDES
52Acute otitis mediaOFFSIDES
53Acute sinusitisOFFSIDES
54AgitationSIDER
55AgraphiaOFFSIDES
56AlopeciaOFFSIDES
SIDER
57Altered bowel functionOFFSIDES
58Altered state of consciousnessSIDER
59AmnesiaOFFSIDES
60AnalgesiaOFFSIDES
61Anaphylactic shockSIDER
62Anaphylactoid ReactionSIDER
63AnorexiaOFFSIDES
64ApathyOFFSIDES
65AphagiaOFFSIDES
66AphasiaSIDER
67ArthralgiaSIDER
68AstheniaOFFSIDES
SIDER
69AtelectasisOFFSIDES
70Atrial FibrillationSIDER
71Atrial FlutterSIDER
72AuraOFFSIDES
73Autoimmune hepatitisOFFSIDES
74Biliary DyskinesiaOFFSIDES
75Biliary adenomaOFFSIDES
76Bilirubin abnormalSIDER
77Bipolar DisorderOFFSIDES
78Bipolar I disorderOFFSIDES
79Bladder painSIDER
80BlepharospasmOFFSIDES
81Blood bilirubin abnormalSIDER
82Blood creatine phosphokinase MB increasedOFFSIDES
83Blood potassium decreasedOFFSIDES
84Blurred visionOFFSIDES
85Bone painOFFSIDES
SIDER
86BradycardiaSIDER
87Brain ConcussionOFFSIDES
88Brain natriuretic peptide increasedOFFSIDES
89Breast fibromaOFFSIDES
90BronchitisSIDER
91BruxismOFFSIDES
92Burning sensationSIDER
93Cardiac valve vegetationOFFSIDES
94CausalgiaOFFSIDES
95Cerebral InfarctionSIDER
96Cerebral calcificationOFFSIDES
97Cerebrovascular accidentSIDER
98ChillsSIDER
99ChromaturiaOFFSIDES
100Circumstance or information capable of leading to medication errorOFFSIDES
101Colitis, Ischemic20533112CTD
102Complex partial seizuresOFFSIDES
103ConfabulationOFFSIDES
104Congenital cystic kidney diseaseOFFSIDES
105Contact DermatitisOFFSIDES
106CryingOFFSIDES
107Cutaneous hypersensitivitySIDER
108CystitisSIDER
109CystOFFSIDES
110Cytolytic hepatitisOFFSIDES
111DeafnessOFFSIDES
112DehydrationSIDER
113DemyelinationOFFSIDES
114Depressed Level of ConsciousnessSIDER
115Depressive disorder11167903CTD
SIDER
116DermatitisSIDER
117Detachment psychologicalSIDER
118DiarrheaOFFSIDES
119DiscomfortSIDER
120Disease recurrenceOFFSIDES
121Disseminated Intravascular CoagulationOFFSIDES
122DissociationSIDER
123Disturbance in sexual arousalSIDER
124DiuresisSIDER
125DrowsinessOFFSIDES
SIDER
126Drug ToleranceOFFSIDES
127Drug abuserOFFSIDES
128Drug addictOFFSIDES
129Drug toxicityOFFSIDES
130Drug withdrawal headacheOFFSIDES
131Dry skinOFFSIDES
SIDER
132DysequilibriumSIDER
133DyspareuniaOFFSIDES
134Dyspeptic signs and symptomsSIDER
135DysphasiaOFFSIDES
136Dysthymic DisorderOFFSIDES
SIDER
137DysuriaOFFSIDES
138Embolic strokeOFFSIDES
139EndocarditisOFFSIDES
140EndometriosisOFFSIDES
141EpistaxisOFFSIDES
142Erectile dysfunctionOFFSIDES
143Euphoric moodOFFSIDES
144Exposure to toxic agentOFFSIDES
145Eye painOFFSIDES
SIDER
146Fatigue10972634CTD
OFFSIDES
SIDER
147Feeling abnormalSIDER
148Feeling strangeSIDER
149FolliculitisSIDER
150FormicationOFFSIDES
151GamblingOFFSIDES
152Gamma-Glutamyltransferase IncreasedOFFSIDES
153Gas PoisoningOFFSIDES
154Gastric ulcerSIDER
155GastritisSIDER
156GastroenteritisSIDER
157Gastrointestinal discomfortSIDER
158Gastrointestinal hypomotilityOFFSIDES
159GlycosuriaSIDER
160HELLP SyndromeOFFSIDES
161Hallucinations, mixedOFFSIDES
162HeadacheSIDER
163HemiplegiaOFFSIDES
164HostilitySIDER
165HyperkinesiaSIDER
166HyperventilationOFFSIDES
167HypomaniaOFFSIDES
168HypotensionSIDER
169HypothyroidismSIDER
170HysterectomyOFFSIDES
171InfectionSIDER
172Infectious MononucleosisOFFSIDES
173InflammationSIDER
174Injection site fibrosisOFFSIDES
175Intention tremorOFFSIDES
176Intentional misuseOFFSIDES
177KetonuriaSIDER
178LabyrinthitisSIDER
179LacerationOFFSIDES
180LethargyOFFSIDES
181LeukoencephalopathyOFFSIDES
182Leukopenia neonatalOFFSIDES
183Lumbar radiculopathyOFFSIDES
184Lung consolidationOFFSIDES
185MalaiseSIDER
186MastitisSIDER
187Medication overuse headacheSIDER
188Mental impairmentOFFSIDES
189Mental status changesOFFSIDES
190Metanephrine urine increasedOFFSIDES
191Migraine Disorders

View details

CTD
192Multiple drug overdoseOFFSIDES
193Muscle RigiditySIDER
194Muscle necrosisOFFSIDES
195Musculoskeletal discomfortSIDER
196Musculoskeletal stiffnessSIDER
197MyalgiaSIDER
198Myocardial InfarctionSIDER
199NephrolithiasisOFFSIDES
200Nervous tensionOFFSIDES
201NeuralgiaSIDER
202NeuritisSIDER
203Neutrophil count decreasedOFFSIDES
204Normal deliveryOFFSIDES
205Normetanephrine urine increasedOFFSIDES
206NumbnessSIDER
207Optic Disc EdemaOFFSIDES
208Oral fungal infectionOFFSIDES
209Oral pruritusSIDER
210OsteopeniaOFFSIDES
211PO2 decreasedOFFSIDES
212Pharyngolaryngeal PainOFFSIDES
213PhonophobiaSIDER
214PhotophobiaSIDER
215PleurisySIDER
216PneumoniaSIDER
217PolydipsiaSIDER
218Polysubstance abuseOFFSIDES
219PolyuriaSIDER
220Postoperative adhesionOFFSIDES
221Prescribed overdoseOFFSIDES
222PruritusSIDER
223Pulmonary congestionOFFSIDES
224PurpuraSIDER
225PyelitisSIDER
226PyelonephritisSIDER
227Recurrence10759909
10972634
CTD
228Reflex Sympathetic DystrophyOFFSIDES
229RegurgitationSIDER
230Rheumatic disorderSIDER
231RheumatismSIDER
232RhinitisOFFSIDES
233RhinorrheaOFFSIDES
234Scan with contrastOFFSIDES
235ScotomaOFFSIDES
SIDER
236Serotonin SyndromeSIDER
237ShockSIDER
238Shoulder PainOFFSIDES
239SinusitisSIDER
240Skin lesionOFFSIDES
241Skin necrosisOFFSIDES
242SnoringOFFSIDES
243SomnolenceSIDER
244Spinal fusion surgeryOFFSIDES
245Stevens-Johnson SyndromeOFFSIDES
246StressOFFSIDES
247SweatingSIDER
248SwellingSIDER
249TachyarrhythmiaSIDER
250Therapeutic product effect decreasedCanada Vigilance: 1Canada Vigilance
251ThirstSIDER
252ThrombocytopeniaSIDER
253TinnitusOFFSIDES
SIDER
254TracheitisSIDER
255TremorSIDER
256UlcerSIDER
257Urinary IncontinenceSIDER
258Urine flow decreasedOFFSIDES
259Urine output increasedSIDER
260UrticariaSIDER
261Vascular purpuraSIDER
262VasospasmOFFSIDES
SIDER
263Ventricular FibrillationSIDER
264VertigoSIDER
265Weight GainOFFSIDES
266Wound dehiscenceOFFSIDES
267YawningOFFSIDES
268nervous system disorderSIDER
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.