MetaADEDB 2.0 @ LMMD
Obsessive-Compulsive Disorder
(UMLS:C0028768)
Definition:
An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.
UMLS ID:
C0028768
MeSH ID:
D009771
Classification:
Name:
Mental Disorders
MeSH Tree Number(s):
F03.080.600
Synonym(s)
1.
Obsessive-Compulsive Disorder
2.
Anancastic neurosis
3.
Anankastic neurosis
4.
Disorder;obsessive-compulsive
5.
NEUROSIS, OBSESSIVE COMPULSIVE
6.
Neurosis, obsessive compulsive
7.
OBSESSIVE COMPULSIVE DISORDER
8.
OBSESSIVE COMPULSIVE NEUROSIS
9.
OBSESSIVE-COMPULSIVE DISORDER
10.
OBSESSIVE-COMPULSIVE NEUROSIS
11.
OCD
12.
OCD (obsessive compulsive disorder)
13.
OCD - Obsessive-compulsive disorder
14.
Obsessive Compulsive Disorder
15.
Obsessive Compulsive Neurosis
16.
Obsessive compulsive disorder
17.
Obsessive compulsive disorder, NOS
18.
Obsessive compulsive neurosis
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1AripiprazoleFAERS: 1229

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17414263
17502782
18480697
19644229
19644230
19766686
 		CTD
SIDER
US FAERS
2PramipexoleFAERS: 843
Canada Vigilance: 18		Canada Vigilance
US FAERS
3Aspirin-oxycodone hydrochloride-oxycodone terephthalate combinationFAERS: 116
Canada Vigilance: 1		Canada Vigilance
US FAERS
4ClozapineFAERS: 86
Canada Vigilance: 12

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1487472
1734752
7896662
7921724
8010373
8828993
8890690
9619164
9812137
10401913
10412713
11551293
12372230
15253471
16778711
17464712
19644230
19766686
 		CTD
Canada Vigilance
US FAERS
5SertralineFAERS: 84
Canada Vigilance: 2		Canada Vigilance
US FAERS
6IsotretinoinFAERS: 71US FAERS
7montelukastFAERS: 69US FAERS
8ParoxetineFAERS: 48
Canada Vigilance: 12

View details

7653703
7726327
8027419
10847309
12648899
15253471
15610935
16675374
17464712
17503984
18582189
 		CTD
Canada Vigilance
US FAERS
9MethylphenidateFAERS: 46
Canada Vigilance: 5

View details

9473905
10858915
11221499
11392335
12505824
12907924
 		CTD
SIDER
Canada Vigilance
US FAERS
10RisperidoneFAERS: 39
Canada Vigilance: 3

View details

7592506
8890690
9004062
9619164
9632039
10362445
10616638
10630458
11147933
11874209
12352268
12505824
12880504
14674056
15213579
15253471
18480697
18582189
19644229
 		CTD
Canada Vigilance
US FAERS
11VareniclineFAERS: 39
Canada Vigilance: 3		Canada Vigilance
US FAERS
12Ethylene GlycolFAERS: 36US FAERS
13SertralineFAERS: 34

View details

8010373
9812137
10461823
10900533
11589524
15819475
16553533
17438226
24194395
24865413
 		CTD
US FAERS
14AlendronateFAERS: 31US FAERS
15Atomoxetine HydrochlorideFAERS: 31
Canada Vigilance: 1		Canada Vigilance
US FAERS
16ropiniroleFAERS: 31US FAERS
17Lisdexamfetamine DimesylateFAERS: 25
Canada Vigilance: 2		26621156CTD
Canada Vigilance
US FAERS
18FinasterideFAERS: 24US FAERS
19OlanzapineFAERS: 24

View details

9619164
10327925
10974610
11147933
11874209
12107623
 		CTD
US FAERS
20Venlafaxine HydrochlorideFAERS: 22
Canada Vigilance: 1		17503984CTD
Canada Vigilance
US FAERS
21ziprasidoneFAERS: 20
Canada Vigilance: 1		19644229CTD
Canada Vigilance
US FAERS
22Duloxetine HydrochlorideFAERS: 19
Canada Vigilance: 1		Canada Vigilance
US FAERS
23Quetiapine FumarateFAERS: 19
Canada Vigilance: 2		Canada Vigilance
US FAERS
24FluoxetineFAERS: 18
Canada Vigilance: 1		Canada Vigilance
US FAERS
25LevetiracetamFAERS: 18US FAERS
26LamotrigineFAERS: 17
Canada Vigilance: 5		Canada Vigilance
US FAERS
274-hydroxybutyric acidFAERS: 15US FAERS
28FluoxetineFAERS: 15
Canada Vigilance: 2

View details

1552034
1883009
1919549
2005077
2258456
2549018
7726327
7961535
8071291
8151009
8253700
8292312
8407756
8848522
8923100
9546514
9632039
9717345
10327925
10505588
12046001
14674056
15213579
20418887
 		CTD
Canada Vigilance
US FAERS
29Quetiapine FumarateFAERS: 1514509206
15858452		CTD
US FAERS
30AlprazolamFAERS: 13US FAERS
31rofecoxibFAERS: 13US FAERS
32MethylphenidateFAERS: 12US FAERS
33carbidopa, levodopa drug combinationFAERS: 12US FAERS
34CitalopramFAERS: 10
Canada Vigilance: 1

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3458554
12505824
15213579
15491244
15642451
17873697
18582189
21152153
 		CTD
SIDER
Canada Vigilance
US FAERS
35Lurasidone HydrochlorideFAERS: 10US FAERS
36MethylphenidateFAERS: 10
Canada Vigilance: 2		Canada Vigilance
US FAERS
37CitalopramFAERS: 9
Canada Vigilance: 1		Canada Vigilance
US FAERS
38ClonazepamFAERS: 9
Canada Vigilance: 3		1527234CTD
Canada Vigilance
US FAERS
39PregabalinFAERS: 9US FAERS
40CabergolineFAERS: 8US FAERS
41ParoxetineFAERS: 8US FAERS
42PramipexoleFAERS: 8
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
43CitalopramFAERS: 7US FAERS
44Dimethyl FumarateFAERS: 7US FAERS
45LevofloxacinFAERS: 7US FAERS
46NuvaRingFAERS: 7
Canada Vigilance: 1		Canada Vigilance
US FAERS
47PramipexoleFAERS: 7US FAERS
48Venlafaxine HydrochlorideFAERS: 7US FAERS
49rotigotineFAERS: 7SIDER
US FAERS
502-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chlorideFAERS: 6
Canada Vigilance: 1		Canada Vigilance
US FAERS
51BromocriptineFAERS: 6US FAERS
52Desvenlafaxine SuccinateFAERS: 6US FAERS
53NorgestrelFAERS: 68601550
9847494		CTD
US FAERS
54TopiramateFAERS: 6US FAERS
55etonogestrelFAERS: 6US FAERS
56AsenapineFAERS: 5US FAERS
57Fingolimod HydrochlorideFAERS: 5US FAERS
58Paliperidone PalmitateFAERS: 5
Canada Vigilance: 1		Canada Vigilance
US FAERS
59TetrabenazineFAERS: 512355681CTD
SIDER
US FAERS
60Valproic AcidFAERS: 5US FAERS
61aripiprazole lauroxilFAERS: 5US FAERS
62Adzenys XR-ODTFAERS: 4US FAERS
63ApomorphineFAERS: 4US FAERS
64CitalopramFAERS: 4US FAERS
65ClomipramineFAERS: 4

View details

1154013
1527234
1552034
1757451
1919549
2607791
3276283
3458554
6805722
7091416
7694926
8071291
8151009
8562664
8835709
8923100
9004062
9316681
10327925
10505588
10770480
11147933
11551293
11551294
12432978
15253471
 		CTD
US FAERS
66Estrogens, Conjugated (USP)FAERS: 4US FAERS
67FluvoxamineFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
68HaloperidolFAERS: 4US FAERS
69MirtazapineFAERS: 415491244CTD
US FAERS
70PrednisoloneFAERS: 48273044CTD
US FAERS
71RivastigmineFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
72Valproic AcidFAERS: 4US FAERS
73Valproic AcidFAERS: 4US FAERS
74pimavanserinFAERS: 4US FAERS
75ropiniroleFAERS: 4US FAERS
76CetirizineFAERS: 3US FAERS
77GabapentinFAERS: 3US FAERS
78Glatiramer AcetateFAERS: 3US FAERS
79GuanfacineFAERS: 3US FAERS
80MethotrexateFAERS: 3US FAERS
81ModafinilFAERS: 3US FAERS
82OctreotideFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
83OndansetronFAERS: 3US FAERS
84OseltamivirFAERS: 3US FAERS
85OxcarbazepineFAERS: 3US FAERS
86RanitidineFAERS: 3US FAERS
87sibutramineFAERS: 3US FAERS
88valdecoxibFAERS: 3US FAERS
89ziprasidoneFAERS: 3US FAERS
90AzithromycinFAERS: 2US FAERS
91BortezomibFAERS: 2US FAERS
92ClomipramineFAERS: 2US FAERS
93CyproheptadineFAERS: 2US FAERS
94EverolimusFAERS: 2US FAERS
95FluticasoneFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
96Insulin GlargineFAERS: 2US FAERS
97IsoniazidFAERS: 22211554CTD
US FAERS
98LacosamideFAERS: 2US FAERS
99LenalidomideFAERS: 2US FAERS
100LeuprolideFAERS: 2US FAERS
101MefloquineFAERS: 2US FAERS
102MethamphetamineFAERS: 2US FAERS
103OmeprazoleFAERS: 2US FAERS
104RibavirinFAERS: 2US FAERS
105TapentadolFAERS: 2US FAERS
106TeriparatideFAERS: 2US FAERS
107TestosteroneFAERS: 2US FAERS
108TramadolFAERS: 2US FAERS
109Vilazodone HydrochlorideFAERS: 2US FAERS
110Vortioxetine hydrobromideFAERS: 2US FAERS
111ZolpidemFAERS: 2US FAERS
112ZonisamideFAERS: 2US FAERS
113aclidinium bromideFAERS: 2US FAERS
114deflazacortFAERS: 2US FAERS
115iloperidoneFAERS: 2SIDER
US FAERS
116montelukastFAERS: 2US FAERS
117oxybutyninFAERS: 2US FAERS
118suvorexantFAERS: 2US FAERS
1194-AminopyridineFAERS: 1US FAERS
120AdderallFAERS: 1US FAERS
121Advil PMFAERS: 1US FAERS
122AlbuterolFAERS: 1US FAERS
123AmitriptylineFAERS: 1US FAERS
124AmoxicillinFAERS: 1US FAERS
125AmphetamineFAERS: 1US FAERS
126Anoro ElliptaFAERS: 1US FAERS
127AtorvastatinFAERS: 1US FAERS
128AustedoFAERS: 1US FAERS
129BaclofenFAERS: 1US FAERS
130BromocriptineFAERS: 1US FAERS
131BudesonideFAERS: 1US FAERS
132CannabidiolFAERS: 1US FAERS
133CarbamazepineFAERS: 1US FAERS
134CarbidopaFAERS: 1US FAERS
135CarvedilolFAERS: 1US FAERS
136ChlordiazepoxideFAERS: 1US FAERS
137CiprofloxacinFAERS: 1US FAERS
138ClarithromycinFAERS: 1US FAERS
139ClobazamFAERS: 1US FAERS
140ClomipheneFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
141ClonidineFAERS: 1US FAERS
142Cyproheptadine hydrochlorideFAERS: 1US FAERS
143Deamino Arginine VasopressinFAERS: 1US FAERS
144DexamethasoneFAERS: 16834027
16145191		CTD
US FAERS
145DextroamphetamineFAERS: 12217661
12505824		CTD
US FAERS
146DiazepamFAERS: 1US FAERS
147DicyclomineFAERS: 1US FAERS
148DiphenhydramineFAERS: 1US FAERS
149DroxidopaFAERS: 1US FAERS
150Duloxetine HydrochlorideFAERS: 1US FAERS
151EszopicloneFAERS: 1US FAERS
152FenofibrateFAERS: 1US FAERS
153Fluticasone-Salmeterol Drug CombinationFAERS: 1US FAERS
154GuaifenesinFAERS: 1US FAERS
155GuanfacineFAERS: 1US FAERS
156IbuprofenFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
157Imatinib MesylateFAERS: 1US FAERS
158Insulin DetemirFAERS: 1US FAERS
159InsulinFAERS: 1US FAERS
160IvabradineFAERS: 1US FAERS
161KetamineFAERS: 1US FAERS
162Ketorolac TromethamineFAERS: 1US FAERS
163LorazepamFAERS: 1US FAERS
164LoxapineFAERS: 1US FAERS
165MDV 3100FAERS: 1US FAERS
166Medroxyprogesterone AcetateFAERS: 1US FAERS
167MefloquineFAERS: 1US FAERS
168MemantineFAERS: 1US FAERS
169MercaptopurineFAERS: 1US FAERS
170MesoridazineFAERS: 1US FAERS
171MethadoneFAERS: 1US FAERS
172MethotrexateFAERS: 1US FAERS
173MethylprednisoloneFAERS: 1US FAERS
174ModafinilFAERS: 1US FAERS
175MorphineFAERS: 1US FAERS
176NaltrexoneFAERS: 1SIDER
US FAERS
177NortriptylineFAERS: 1US FAERS
178Olanzapine pamoateFAERS: 1US FAERS
179Olmesartan MedoxomilFAERS: 1US FAERS
180PergolideFAERS: 1US FAERS
181PergolideFAERS: 1
Canada Vigilance: 2		Canada Vigilance
US FAERS
182PhenelzineFAERS: 13565632CTD
US FAERS
183PhentermineFAERS: 19829290CTD
US FAERS
184PimozideFAERS: 1US FAERS
185PravastatinFAERS: 1US FAERS
186PrednisoneFAERS: 1
Canada Vigilance: 1		15819475CTD
Canada Vigilance
US FAERS
187PropranololFAERS: 1US FAERS
188RamiprilFAERS: 1US FAERS
189RivaroxabanFAERS: 1US FAERS
190Rosuvastatin CalciumFAERS: 1US FAERS
191Ruxolitinib phosphateFAERS: 1US FAERS
192SelegilineFAERS: 1US FAERS
193SimvastatinFAERS: 1US FAERS
194SulfasalazineFAERS: 1US FAERS
195TacrolimusFAERS: 1US FAERS
196TenofovirFAERS: 1US FAERS
197TenofovirFAERS: 1US FAERS
198TerbinafineFAERS: 1US FAERS
199TerbutalineFAERS: 1US FAERS
200ThioridazineFAERS: 1US FAERS
201ThyroxineFAERS: 1US FAERS
202ThyroxineFAERS: 1US FAERS
203TimololFAERS: 1US FAERS
204Tiotropium BromideFAERS: 1US FAERS
205Triamcinolone AcetonideFAERS: 1US FAERS
206TrimethoprimFAERS: 1US FAERS
207ValsartanFAERS: 1US FAERS
208VareniclineFAERS: 1US FAERS
209VoriconazoleFAERS: 1US FAERS
210VortioxetineFAERS: 1US FAERS
211acetaminophen, aspirin, caffeine drug combinationFAERS: 1US FAERS
212adefovir dipivoxilFAERS: 1US FAERS
213apixabanFAERS: 1US FAERS
214apremilastFAERS: 1US FAERS
215brexpiprazoleFAERS: 1US FAERS
216chloroquine diphosphateFAERS: 1US FAERS
217dofetilideFAERS: 1US FAERS
218norgestimate, ethinyl estradiol drug combinationFAERS: 1US FAERS
219palbociclibFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
220rasagilineFAERS: 1US FAERS
221sapropterinFAERS: 1US FAERS
222teriflunomideFAERS: 1US FAERS
223tofacitinibFAERS: 1US FAERS
224valbenazineFAERS: 1US FAERS
2251-(3-chlorophenyl)piperazine3276283CTD
226Azathioprine15911917CTD
227Buspirone1552034
2258456		CTD
228Chlorpromazine8890690CTD
229Clonidine1876628CTD
230Cocaine7987186CTD
231Codeine2763855CTD
232DeferiproneSIDER
233Dexfenfluramine9829290CTD
234Estradiol9847494CTD
235FluvoxamineCanada Vigilance: 1

View details

1906498
7568372
7592506
8151009
8828993
9232209
11098342
12456895
12823077
15253471
16146185
17630870
 		CTD
Canada Vigilance
236ImipramineCanada Vigilance: 1Canada Vigilance
237Inositol15214512CTD
238Lithium1777530
15213579		CTD
239MesalamineCanada Vigilance: 1Canada Vigilance
240Methamphetamine10362445
20358305		CTD
241MethyldopaCanada Vigilance: 1Canada Vigilance
242N-Methyl-3,4-methylenedioxyamphetamine17853269CTD
243Nicotine26688438CTD
244Nortriptyline17089931CTD
245Quinpirole27659555CTD
246Selegiline16730214CTD
247Sumatriptan10621951CTD
248Tranylcypromine2335494CTD
249Trazodone2521065
7726327		CTD
250Zoledronic AcidCanada Vigilance: 1Canada Vigilance
251drospirenone and ethinyl estradiol combinationCanada Vigilance: 1Canada Vigilance
Similar ADE(s)
NameSemantic Similarity
1Neurotic Disorders45%
2Agoraphobia42.9%
3Claustrophobia42.9%
4Panic Disorder42.9%
5Hyperkinetic Heart Syndrome42.9%
6Separation Anxiety Disorder38.1%
7Avoidant Personality Disorder23.1%
8Dissociative disorder23.1%
9Frigidity23.1%
10Hypoactive Sexual Desire Disorder23.1%
11Disruptive, Impulse Control, and Conduct Disorders23.1%
12Intermittent Explosive Disorder23.1%
13Kleptomania23.1%
14Narcissistic Personality Disorder23.1%
15Personality Disorders23.1%
16Sexual Aversion Disorder23.1%
17Somatoform Disorder23.1%
18Dissociation23.1%
19Motor Disorders23.1%
20Mood Disorders23.1%
21Schizophrenia Spectrum and Other Psychotic Disorders23.1%
22Neurodevelopmental Disorders23.1%
23Neurocognitive Disorders23.1%
24Feeding and Eating Disorders23.1%
25Drug abuse15.8%
26Substance Dependence15.8%
27Substance-Related Disorders15.8%
28Drug Dependence15.8%
29Adjustment Disorders14.3%
30Affective Disorders, Psychotic14.3%
31Anorexia Nervosa14.3%
32Antisocial Personality Disorder14.3%
33Bipolar Disorder14.3%
34Body Dysmorphic Disorders14.3%
35Borderline Personality Disorder14.3%
36Capgras Syndrome14.3%
37Child Behavior Disorders14.3%
38Developmental Disabilities14.3%
39Child Development Disorders, Pervasive14.3%
40Cognition Disorders14.3%
41Conversion disorder14.3%
42Cyclothymic Disorder14.3%
43Dependent Personality Disorder14.3%
44Depressive disorder14.3%
45Developmental Coordination Disorder14.3%
46Exhibitionism14.3%
47Factitious Disorders14.3%
48Firesetting Behavior14.3%
49Head Banging14.3%
50Histrionic Personality Disorder14.3%
51Hypochondriasis14.3%
52Masochism14.3%
53Melancholia14.3%
54Motor Skills Disorders14.3%
55Dissociative Identity Disorder14.3%
56Neurasthenia14.3%
57Oppositional Defiant Disorder14.3%
58Paranoid Personality Disorder14.3%
59Pedophilia14.3%
60Pseudodementia14.3%
61Psychotic Disorders14.3%
62Sadism14.3%
63Schizoaffective Disorder14.3%
64Schizoid Personality Disorder14.3%
65Schizophrenia14.3%
66Schizophrenia, Childhood14.3%
67Schizotypal Personality Disorder14.3%
68Stereotypic Movement Disorder14.3%
69Transvestism14.3%
70Trichotillomania14.3%
71Voyeurism14.3%
72Attention Deficit and Disruptive Behavior Disorders14.3%
73Reactive Attachment Disorder14.3%
74Sexual and Gender Disorders14.3%
75Gender Dysphoria14.3%
76Paranoia14.3%
77Compulsive Personality Disorder14.3%
78Bulimia Nervosa14.3%
79Sleep Wake Disorders11.3%
80Combat Disorders10.3%
81Dysthymic Disorder10.3%
82Hysteria10.3%
83Schizophrenia, Catatonic10.3%
84Schizophrenia, Disorganized10.3%
85Post-Traumatic Stress Disorder10.3%
86Attention Deficit Disorder10.3%
87Seasonal Affective Disorder10.3%
88Conduct Disorder10.3%
89Social Communication Disorder10.3%
90Psychological Trauma10.3%
91Phonological Disorder10.3%
92Psychoses, Substance-Induced9.9%
93Marijuana Abuse9.5%
94Opioid-Related Disorders9.5%
95Nicotine Dependence9.5%
96Opioid abuse9.5%
97Parasomnia9.5%
98Phencyclidine Abuse9.5%
99Substance Abuse, Intravenous9.5%
100Substance Withdrawal Syndrome9.5%
101Tobacco Use Disorder9.5%
102Alcohol-Related Disorders9.5%
103Amphetamine-Related Disorders9.5%
104Cocaine-Related Disorders9.5%
105Dyssomnias9.5%
106Gambling9.3%
107Premature Ejaculation9.3%
108Erectile dysfunction9.3%
109Dementia9.3%
110Autistic Disorder8.5%
111Asperger Syndrome8.5%
112Psychoses, Alcoholic7.3%
113Neonatal Abstinence Syndrome7.1%
114Dyspareunia6.8%
115Alcohol Use Disorder6.8%
116Alcoholic Intoxication6.8%
117Heroin Dependence6.8%
118Morphine Dependence6.8%
119Alcohol abuse6.8%
120Depression, Postpartum6.8%
121Sleep Talking6.8%
122Sleep Disorders, Intrinsic6.8%
123Kluver-Bucy Syndrome6.7%
124Premenstrual Dysphoric Disorder6.7%
125Mutism6.7%
126Selective Mutism6.7%
127Restless Legs Syndrome6.3%
128Alcohol Withdrawal Delirium5.7%
129Disorders of Excessive Somnolence5.6%
130Sleep Initiation and Maintenance Disorders5.6%
131Night Terrors5.6%
132Somnambulism5.6%
133Transient Insomnia5.6%
134Sleep Paralysis5.6%
135Chronic Insomnia5.6%
136REM Sleep Behavior Disorder5.6%
137Hypersomnia5.6%
138Consciousness Disorders5.5%
139Mental Retardation5.5%
140Depressed Level of Consciousness5.5%
141Mental deficiency5.5%
142Intellectual Disability5.5%
143Enuresis5.4%
144Amnesia5.4%
145Delirium5.4%
146Dissociative Amnesia5.4%
147Global Amnesia5.4%
148Sleep Bruxism5.1%
149Presenile dementia5%
150Senile dementia5%
151Binge Drinking5%
152Creutzfeldt-Jakob disease5%
153Huntington Disease5%
154Dyscalculia4.9%
155Narcolepsy4.9%
156Kleine-Levin Syndrome4.9%
157Pick Disease of the Brain4.9%
158Alexia, Pure4.9%
159Cataplexy4.6%
160Sleep Disorders, Circadian Rhythm4.3%
161Sleep Deprivation4%
162Diurnal Enuresis4%
163Retrograde amnesia3.9%
164Amnesia, Anterograde3.9%
165Lewy Body Disease3.3%
166Wernicke Encephalopathy3.3%
167AIDS Dementia Complex3.3%
168Amnesia, Transient Global3.3%
169Frontotemporal dementia3.3%
170Alexia3.3%
171Dyslexia3.3%
172Auditory Perceptual Disorders2.8%
173Jet Lag Syndrome2.8%
174Dementia, Vascular2.4%
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