MetaADEDB 2.0 @ LMMD
Chlordiazepoxide
(BUCORZSTKDOEKQ-UHFFFAOYSA-N)
Structure
SMILES
CN=C1CN(O)C(=c2c(=N1)ccc(c2)Cl)c1ccccc1
Type(s)
Approved; Illicit; Investigational
ATC code(s)
N05BA02
Molecular Formula:
C16H14ClN3O
Molecular Weight:
299.755
Log P:
1.2227
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
1
TPSA:
48.19
CAS Number(s):
58-25-3
Synonym(s)
1.
Chlordiazepoxide
2.
Methaminodiazepoxide
3.
7-Chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepine-4-oxide
4.
7-Chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide
5.
Chlordiazepoxide Hydrobromide
6.
Chlordiazepoxide Hydrochloride
7.
Chlordiazepoxide Monohydrochloride
8.
Chlordiazepoxide Perchlorate
9.
Chlozepid
10.
Elenium
11.
Librium
12.
7 Chloro 2 methylamino 5 phenyl 3H 1,4 benzodiazepine 4 oxide
13.
7 Chloro N methyl 5 phenyl 3H 1,4 benzodiazepin 2 amine 4 oxide
14.
Hydrobromide, Chlordiazepoxide
15.
Hydrochloride, Chlordiazepoxide
16.
Monohydrochloride, Chlordiazepoxide
17.
Perchlorate, Chlordiazepoxide
External Link(s)
MeSHD002707
PubChem Compound2712
BindingDB50007664
ChEBI94781
CHEMBLCHEMBL451
DrugBankDB00475
DrugCentral594
IUPHAR/BPS Guide to PHARMACOLOGY3370
KEGGdr:D00267
Therapeutic Target DatabaseD06BEP
ZINC19632917
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AnxietyFAERS: 5OFFSIDES
US FAERS
2Feeling abnormalFAERS: 5SIDER
US FAERS
3Stevens-Johnson SyndromeFAERS: 5
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
4SomnolenceFAERS: 4
Canada Vigilance: 17
Canada Vigilance
SIDER
US FAERS
5DizzinessFAERS: 3
Canada Vigilance: 8
2000517CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
6Drug ineffectiveFAERS: 3US FAERS
7Drug withdrawal syndromeFAERS: 3US FAERS
8Mental status changesFAERS: 3OFFSIDES
US FAERS
9Suicide attemptFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
10Alanine Aminotransferase IncreasedFAERS: 2OFFSIDES
US FAERS
11Aspartate Aminotransferase IncreasedFAERS: 2US FAERS
12AstheniaFAERS: 2
Canada Vigilance: 2
Canada Vigilance
OFFSIDES
US FAERS
13Burning sensationFAERS: 2US FAERS
14CatatoniaFAERS: 2US FAERS
15Chest PainFAERS: 2OFFSIDES
US FAERS
16FatigueFAERS: 2
Canada Vigilance: 1
2000517
4479092
CTD
OFFSIDES
Canada Vigilance
US FAERS
17HypersomniaFAERS: 2US FAERS
18Memory impairmentFAERS: 2US FAERS
19NauseaFAERS: 2
Canada Vigilance: 2
5354861CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
20OverdoseFAERS: 2
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
21SyncopeFAERS: 2
Canada Vigilance: 3
Canada Vigilance
SIDER
US FAERS
22Toxicity to various agentsFAERS: 2US FAERS
23TremorFAERS: 2
Canada Vigilance: 3
Canada Vigilance
US FAERS
24Abdominal discomfortFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
25AbuliaFAERS: 1US FAERS
26Accidental overdoseFAERS: 1
Canada Vigilance: 4
Canada Vigilance
OFFSIDES
US FAERS
27AmnesiaFAERS: 1
Canada Vigilance: 1

View details

CTD
OFFSIDES
Canada Vigilance
US FAERS
28AngerFAERS: 1OFFSIDES
US FAERS
29AngioedemaFAERS: 1
Canada Vigilance: 2
Canada Vigilance
US FAERS
30ArthralgiaFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
31Blood alkaline phosphatase increasedFAERS: 1US FAERS
32Blood glucose increasedFAERS: 1US FAERS
33Cerebral atrophyFAERS: 1OFFSIDES
US FAERS
34ChillsFAERS: 1US FAERS
35ChokingFAERS: 1US FAERS
36Completed SuicideFAERS: 1
Canada Vigilance: 8
Canada Vigilance
OFFSIDES
US FAERS
37Depressed Level of ConsciousnessFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
38Drug DependenceFAERS: 1US FAERS
39Drug dispensing errorFAERS: 1US FAERS
40Drug dose omissionFAERS: 1OFFSIDES
US FAERS
41Drug level increasedFAERS: 1US FAERS
42Drug screen positiveFAERS: 1OFFSIDES
US FAERS
43DysarthriaFAERS: 1
Canada Vigilance: 3
Canada Vigilance
US FAERS
44DysgeusiaFAERS: 1US FAERS
45DysphoniaFAERS: 1OFFSIDES
US FAERS
46General physical condition abnormalFAERS: 1US FAERS
47HeadacheFAERS: 12000517
5354861
CTD
US FAERS
48Hepatic EncephalopathyFAERS: 1US FAERS
49HepatotoxicityFAERS: 1US FAERS
50HyperacusisFAERS: 1US FAERS
51HypersensitivityFAERS: 1US FAERS
52IncoherentFAERS: 1OFFSIDES
US FAERS
53LethargyFAERS: 1OFFSIDES
US FAERS
54Lip swellingFAERS: 1US FAERS
55MalaiseFAERS: 1US FAERS
56Medication ErrorFAERS: 1US FAERS
57Mood swingsFAERS: 1US FAERS
58Muscle RigidityFAERS: 1US FAERS
59Muscle tightnessFAERS: 1US FAERS
60MydriasisFAERS: 1US FAERS
61MyoclonusFAERS: 1US FAERS
62NegativismFAERS: 1US FAERS
63NervousnessFAERS: 1US FAERS
64Obsessive-Compulsive DisorderFAERS: 1US FAERS
65OverweightFAERS: 1US FAERS
66PolydipsiaFAERS: 1US FAERS
67Poor quality sleepFAERS: 1US FAERS
68PosturingFAERS: 1US FAERS
69Product quality issueFAERS: 1US FAERS
70Quality of life decreasedFAERS: 1US FAERS
71RestlessnessFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
72RhabdomyolysisFAERS: 1US FAERS
73SinusitisFAERS: 1OFFSIDES
US FAERS
74SoporFAERS: 1US FAERS
75Tongue bitingFAERS: 1US FAERS
76Unresponsive to stimuliFAERS: 1OFFSIDES
US FAERS
77UrticariaFAERS: 1
Canada Vigilance: 9
Canada Vigilance
US FAERS
78VerbigerationFAERS: 1US FAERS
79VomitingFAERS: 1US FAERS
80Weight decreasedFAERS: 1US FAERS
81Wrong technique in product usage processFAERS: 1US FAERS
82jaundiceFAERS: 14479092
4952749
CTD
SIDER
US FAERS
83nervous system disorderFAERS: 1US FAERS
84AbasiaOFFSIDES
85Abdominal PainOFFSIDES
86Abdominal massOFFSIDES
87Abnormalities, Drug-Induced6435276CTD
88AbuseOFFSIDES
89Accidental deathOFFSIDES
90AcidosisOFFSIDES
91Actinic keratosisOFFSIDES
92Acute bronchitisOFFSIDES
93Affective Disorders, Psychotic6411158CTD
94AgitationCanada Vigilance: 1Canada Vigilance
95AgoraphobiaOFFSIDES
96AgranulocytosisSIDER
97AgraphiaOFFSIDES
98Alcohol Withdrawal Delirium7220787CTD
99Alcohol abuseOFFSIDES
100Alcohol consumptionOFFSIDES
101Alcohol interactionCanada Vigilance: 1Canada Vigilance
102Alcohol poisoningOFFSIDES
103Alcohol problemCanada Vigilance: 1Canada Vigilance
OFFSIDES
104Alcohol withdrawal syndromeOFFSIDES
105Alcohol-Induced Disorders21127120CTD
106AlveolitisOFFSIDES
107AnalgesiaOFFSIDES
108AnhidrosisOFFSIDES
109Animal biteOFFSIDES
110Ankle FractureOFFSIDES
111Anorexia17987061CTD
OFFSIDES
112AnosmiaOFFSIDES
113Anoxic EncephalopathyOFFSIDES
114Antiphospholipid SyndromeOFFSIDES
115Anxiety Disorders

View details

CTD
116Aortic valve sclerosisOFFSIDES
117AphagiaOFFSIDES
118Application site erythemaOFFSIDES
119Application site irritationOFFSIDES
120Application site pruritusOFFSIDES
121ArteriosclerosisOFFSIDES
122ArthropathyOFFSIDES
123AsphyxiaCanada Vigilance: 1Canada Vigilance
124AtaxiaCanada Vigilance: 54836379
6117919
CTD
SIDER
Canada Vigilance
125AtelectasisOFFSIDES
126AtherosclerosisOFFSIDES
127AuraOFFSIDES
128Back disorderOFFSIDES
129Biliary cirrhosisOFFSIDES
130Bipolar DisorderOFFSIDES
131BlepharospasmOFFSIDES
132Blood bilirubin abnormalOFFSIDES
133Blood glucose abnormalOFFSIDES
134Blood iron decreasedOFFSIDES
135Blood pH decreasedOFFSIDES
136Blood thyroid stimulating hormone abnormalOFFSIDES
137Blood thyroid stimulating hormone increasedOFFSIDES
138Blood urea increasedOFFSIDES
139Blood urine presentOFFSIDES
140Blue Toe SyndromeOFFSIDES
141Blurred visionOFFSIDES
142Bone density decreasedOFFSIDES
143Bradycardia1266496CTD
144BronchiectasisOFFSIDES
145BronchitisOFFSIDES
146BruxismOFFSIDES
147BursitisOFFSIDES
148Cardiac FlutterOFFSIDES
149Cardioactive drug level increasedOFFSIDES
150CardiotoxicityOFFSIDES
151Catalepsy33340CTD
152CataractOFFSIDES
153CellulitisOFFSIDES
154Chemical and Drug Induced Liver Injury4479092CTD
155Choking sensationOFFSIDES
156Cholestasis4952749CTD
157Chronic Obstructive Airway DiseaseOFFSIDES
158Clostridium colitisOFFSIDES
159Cocaine-Related Disorders1584846CTD
160Colonic StenosisOFFSIDES
161Complex partial seizuresOFFSIDES
162ConfabulationOFFSIDES
163Confusion5354861CTD
164Congenital tricuspid valve incompetenceOFFSIDES
165ConstipationCanada Vigilance: 1Canada Vigilance
SIDER
166Crohn Disease18711101CTD
167CryingOFFSIDES
168Culture positiveOFFSIDES
169DeliriumCanada Vigilance: 12710011CTD
Canada Vigilance
170Dental FistulaOFFSIDES
171DependenceOFFSIDES
172DermatitisCanada Vigilance: 1Canada Vigilance
173DiabetesOFFSIDES
174Diabetes mellitus inadequate controlOFFSIDES
175Diarrhea2000517CTD
OFFSIDES
176DiplopiaCanada Vigilance: 3Canada Vigilance
177Disorders of Excessive Somnolence2710011
4836379
CTD
178Disseminated Intravascular CoagulationOFFSIDES
179Disturbance in sexual arousalSIDER
180DiverticulumOFFSIDES
181DrowsinessOFFSIDES
SIDER
182Drug ToleranceOFFSIDES
183Drug abuserOFFSIDES
184Drug addictOFFSIDES
185Drug toxicityOFFSIDES
186Drug withdrawal convulsionsOFFSIDES
187Drug withdrawal headacheOFFSIDES
188Dysthymic DisorderOFFSIDES
189DystoniaCanada Vigilance: 1Canada Vigilance
190DysuriaCanada Vigilance: 1Canada Vigilance
191EcchymosisCanada Vigilance: 2Canada Vigilance
192Economic problemOFFSIDES
193EczemaCanada Vigilance: 2Canada Vigilance
194Ejection Fraction DecreasedOFFSIDES
195EmbolismOFFSIDES
196Emotional disorderCanada Vigilance: 1Canada Vigilance
OFFSIDES
197Enzyme abnormalityOFFSIDES
198EpilepsyOFFSIDES
199Erythema MultiformeCanada Vigilance: 3Canada Vigilance
200Erythema NodosumCanada Vigilance: 2Canada Vigilance
201ErythemaCanada Vigilance: 5Canada Vigilance
202Extremity necrosisOFFSIDES
203Eye RednessOFFSIDES
204Failure to ThriveOFFSIDES
205Fatty LiverOFFSIDES
206Fixed eruptionCanada Vigilance: 1Canada Vigilance
207Flat affectOFFSIDES
208Foreign body traumaOFFSIDES
209FormicationOFFSIDES
210Gait inabilityCanada Vigilance: 1Canada Vigilance
211GastritisCanada Vigilance: 1Canada Vigilance
212GastroduodenitisOFFSIDES
213Gastrointestinal motility disorderOFFSIDES
214Gastrointestinal obstructionOFFSIDES
215General physical conditionOFFSIDES
216Gestational DiabetesOFFSIDES
217Hallucinations, mixedOFFSIDES
218Hallucinations5667241CTD
219HemiparesisOFFSIDES
220Hepatic necrosisOFFSIDES
221Hepatitis COFFSIDES
222HepatosplenomegalyOFFSIDES
223HomicideOFFSIDES
224HypercapniaOFFSIDES
225HyperventilationCanada Vigilance: 1Canada Vigilance
226HypervigilanceOFFSIDES
227Hypotension4988497CTD
228IleitisOFFSIDES
229Inappropriate affectOFFSIDES
230IncontinenceOFFSIDES
231Injection site erythemaOFFSIDES
232Injection site painCanada Vigilance: 1Canada Vigilance
233Injection site urticariaOFFSIDES
234Intention tremorOFFSIDES
235Intentional misuseOFFSIDES
236Intentional self-injuryOFFSIDES
237Keratitis siccaOFFSIDES
238LacerationOFFSIDES
239Left Ventricular HypertrophyOFFSIDES
240LeukopeniaCanada Vigilance: 1Canada Vigilance
241Ligament injuryOFFSIDES
242Limb injuryOFFSIDES
243Livedo ReticularisOFFSIDES
244LividityOFFSIDES
245Localised intraabdominal fluid collectionOFFSIDES
246Lumbar radiculopathyOFFSIDES
247MacrocytosisOFFSIDES
248Male Orgasmic DisorderOFFSIDES
249Mental impairmentOFFSIDES
250Metabolic acidosisOFFSIDES
251MononeuritisOFFSIDES
252Morbid thoughtsOFFSIDES
253Multiple drug overdoseOFFSIDES
254Multiple drug overdose intentionalOFFSIDES
255Muscle WeaknessOFFSIDES
256Musculoskeletal PainOFFSIDES
257Musculoskeletal discomfortOFFSIDES
258Musculoskeletal stiffnessOFFSIDES
259MutismCanada Vigilance: 1Canada Vigilance
260MyalgiaCanada Vigilance: 1Canada Vigilance
261Nervous tensionOFFSIDES
262Neural Tube Defects6435276CTD
263Nicotine DependenceOFFSIDES
264No adverse effectOFFSIDES
265NystagmusOFFSIDES
266Oral mucosal exfoliationOFFSIDES
267Oral polypectomyOFFSIDES
268Oral torusOFFSIDES
269OsteochondrosisOFFSIDES
270OsteomyelitisOFFSIDES
271PainOFFSIDES
272PalpitationsCanada Vigilance: 1Canada Vigilance
273PancreatitisOFFSIDES
274ParanoiaOFFSIDES
275Paranoid Personality DisorderOFFSIDES
276Penile Diseases2872065CTD
277PericarditisOFFSIDES
278Peripheral arterial occlusive diseaseOFFSIDES
279Personality ChangeOFFSIDES
280PetechiaeCanada Vigilance: 2Canada Vigilance
281PleurisyOFFSIDES
282Polymyalgia RheumaticaOFFSIDES
283PolyuriaOFFSIDES
284Poor peripheral circulationOFFSIDES
285Poor quality drug administeredOFFSIDES
286Post procedural complicationOFFSIDES
287Post procedural constipationOFFSIDES
288Post procedural discomfortOFFSIDES
289Prenatal Injuries6435276CTD
290Procedural complicationOFFSIDES
291PruritusCanada Vigilance: 64952749CTD
Canada Vigilance
292Psychoses, Substance-Induced4834427
5354861
CTD
293Pulmonary congestionOFFSIDES
294Rash erythematousCanada Vigilance: 2Canada Vigilance
295Rectal polypOFFSIDES
296Renal cystOFFSIDES
297Respiratory arrestCanada Vigilance: 1Canada Vigilance
298Retinal Artery OcclusionOFFSIDES
299Retinal Vein OcclusionOFFSIDES
300RhinorrheaOFFSIDES
301Risus sardonicusOFFSIDES
302Schizoaffective DisorderOFFSIDES
303Seizures1803
2436354
2905779
CTD
304ShockSIDER
305Shoulder PainOFFSIDES
306Sinus headacheOFFSIDES
307Skin lacerationOFFSIDES
308Skin reactionCanada Vigilance: 2Canada Vigilance
309Sleep TalkingOFFSIDES
310StuporCanada Vigilance: 1Canada Vigilance
311Substance Withdrawal Syndrome

View details

CTD
312SynovitisOFFSIDES
313TachycardiaCanada Vigilance: 2Canada Vigilance
314TachyphreniaOFFSIDES
315Tardive DyskinesiaOFFSIDES
316TendinitisOFFSIDES
317Therapeutic response unexpectedOFFSIDES
318ThrombocytopeniaCanada Vigilance: 1Canada Vigilance
319TinnitusOFFSIDES
320Tobacco userOFFSIDES
321Tooth LossOFFSIDES
322UlcerOFFSIDES
323Urogenital Abnormalities6435276CTD
324Vascular painCanada Vigilance: 1Canada Vigilance
325Venous InsufficiencyOFFSIDES
326Venous stasisOFFSIDES
327Ventricular FibrillationCanada Vigilance: 1Canada Vigilance
328VertigoCanada Vigilance: 25547475CTD
Canada Vigilance
329Vitreous DetachmentOFFSIDES
330Weaning failureOFFSIDES
331Wrong technique in drug usage processOFFSIDES
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