MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Seasonal Affective Disorder

(UMLS:C0085159)

Definition:: A syndrome characterized by depressions that recur annually at the same time each year, usually during the winter months. Other symptoms include anxiety, irritability, decreased energy, increased appetite (carbohydrate cravings), increased duration of sleep, and weight gain. SAD (seasonal affective disorder) can be treated by daily exposure to bright artificial lights (PHOTOTHERAPY), during the season of recurrence.
UMLS ID:: C0085159
MeSH ID:: D016574

Classification:

Name:

Mental Disorders
MeSH Tree Number(s):: F03.600.300.775

Synonym(s)

Seasonal Affective Disorder

SAD

SAD - Seasonal affective disorder

SEASONAL AFFECTIVE DISORDER

Seasonal affective disorder

Seasonal depression

Seasonal mood disorder

depression in a seasonal pattern

depression seasonal pattern

10.

depression; seasonal

11.

seasonal affective disorder

12.

seasonal affective disorder (SAD)

13.

seasonal affective disorders

14.

seasonal depression

15.

seasonal pattern depression

16.

seasonal; depression

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Alendronate	FAERS: 13		US FAERS
2	4-hydroxybutyric acid	FAERS: 4		US FAERS
3	LCZ 696	FAERS: 3		US FAERS
4	Finasteride	FAERS: 2		US FAERS
5	Norgestrel	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
6	ambrisentan	FAERS: 2		US FAERS
7	carbidopa, levodopa drug combination	FAERS: 2		US FAERS
8	Buprenorphine, Naloxone Drug Combination	FAERS: 1		US FAERS
9	Clozapine	FAERS: 1		US FAERS
10	Dimethyl Fumarate	FAERS: 1		US FAERS
11	Duloxetine Hydrochloride	FAERS: 1		US FAERS
12	Ezetimibe	FAERS: 1		US FAERS
13	Isotretinoin	FAERS: 1		US FAERS
14	Nitrous Oxide	FAERS: 1		US FAERS
15	Phenelzine	FAERS: 1		OFFSIDES US FAERS
16	Sertraline	FAERS: 1		US FAERS
17	Varenicline	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
18	apremilast	FAERS: 1		US FAERS
19	aripiprazole lauroxil	FAERS: 1		US FAERS
20	ledipasvir, sofosbuvir drug combination	FAERS: 1		US FAERS
21	montelukast	FAERS: 1		US FAERS
22	valbenazine	FAERS: 1		US FAERS
23	valdecoxib	FAERS: 1		US FAERS
24	Beclomethasone			OFFSIDES
25	Dothiepin			OFFSIDES
26	Fingolimod Hydrochloride	Canada Vigilance: 1		Canada Vigilance
27	Fluorometholone			OFFSIDES
28	Lithium Carbonate			OFFSIDES
29	Lithium		2380163	CTD
30	Melatonin		10710176	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Dysthymic Disorder	46.7%
2	Depression, Postpartum	31.1%
3	Cyclothymic Disorder	31%
4	Premenstrual Dysphoric Disorder	30.8%
5	Neurotic Disorders	19.5%
6	Anxiety Disorders	18.5%
7	Avoidant Personality Disorder	18.5%
8	Dissociative disorder	18.5%
9	Frigidity	18.5%
10	Hypoactive Sexual Desire Disorder	18.5%
11	Disruptive, Impulse Control, and Conduct Disorders	18.5%
12	Intermittent Explosive Disorder	18.5%
13	Kleptomania	18.5%
14	Narcissistic Personality Disorder	18.5%
15	Personality Disorders	18.5%
16	Sexual Aversion Disorder	18.5%
17	Somatoform Disorder	18.5%
18	Dissociation	18.5%
19	Motor Disorders	18.5%
20	Schizophrenia Spectrum and Other Psychotic Disorders	18.5%
21	Neurodevelopmental Disorders	18.5%
22	Neurocognitive Disorders	18.5%
23	Feeding and Eating Disorders	18.5%
24	Separation Anxiety Disorder	14%
25	Drug abuse	12.8%
26	Substance Dependence	12.8%
27	Substance-Related Disorders	12.8%
28	Drug Dependence	12.8%
29	Adjustment Disorders	10.3%
30	Affective Disorders, Psychotic	10.3%
31	Agoraphobia	10.3%
32	Anorexia Nervosa	10.3%
33	Antisocial Personality Disorder	10.3%
34	Bipolar Disorder	10.3%
35	Body Dysmorphic Disorders	10.3%
36	Borderline Personality Disorder	10.3%
37	Capgras Syndrome	10.3%
38	Child Behavior Disorders	10.3%
39	Developmental Disabilities	10.3%
40	Child Development Disorders, Pervasive	10.3%
41	Claustrophobia	10.3%
42	Cognition Disorders	10.3%
43	Conversion disorder	10.3%
44	Dependent Personality Disorder	10.3%
45	Developmental Coordination Disorder	10.3%
46	Exhibitionism	10.3%
47	Factitious Disorders	10.3%
48	Firesetting Behavior	10.3%
49	Head Banging	10.3%
50	Histrionic Personality Disorder	10.3%
51	Hypochondriasis	10.3%
52	Masochism	10.3%
53	Motor Skills Disorders	10.3%
54	Dissociative Identity Disorder	10.3%
55	Neurasthenia	10.3%
56	Obsessive-Compulsive Disorder	10.3%
57	Oppositional Defiant Disorder	10.3%
58	Panic Disorder	10.3%
59	Paranoid Personality Disorder	10.3%
60	Pedophilia	10.3%
61	Pseudodementia	10.3%
62	Psychotic Disorders	10.3%
63	Sadism	10.3%
64	Schizoaffective Disorder	10.3%
65	Schizoid Personality Disorder	10.3%
66	Schizophrenia	10.3%
67	Schizophrenia, Childhood	10.3%
68	Schizotypal Personality Disorder	10.3%
69	Stereotypic Movement Disorder	10.3%
70	Transvestism	10.3%
71	Trichotillomania	10.3%
72	Voyeurism	10.3%
73	Attention Deficit and Disruptive Behavior Disorders	10.3%
74	Hyperkinetic Heart Syndrome	10.3%
75	Reactive Attachment Disorder	10.3%
76	Sexual and Gender Disorders	10.3%
77	Gender Dysphoria	10.3%
78	Paranoia	10.3%
79	Compulsive Personality Disorder	10.3%
80	Bulimia Nervosa	10.3%
81	Sleep Wake Disorders	9.3%
82	Marijuana Abuse	7%
83	Opioid-Related Disorders	7%
84	Nicotine Dependence	7%
85	Opioid abuse	7%
86	Parasomnia	7%
87	Phencyclidine Abuse	7%
88	Substance Abuse, Intravenous	7%
89	Substance Withdrawal Syndrome	7%
90	Tobacco Use Disorder	7%
91	Alcohol-Related Disorders	7%
92	Amphetamine-Related Disorders	7%
93	Cocaine-Related Disorders	7%
94	Dyssomnias	7%
95	Psychoses, Substance-Induced	6.9%
96	Gambling	6.8%
97	Premature Ejaculation	6.8%
98	Erectile dysfunction	6.8%
99	Dementia	6.8%
100	Combat Disorders	6.7%
101	Hysteria	6.7%
102	Schizophrenia, Catatonic	6.7%
103	Schizophrenia, Disorganized	6.7%
104	Post-Traumatic Stress Disorder	6.7%
105	Attention Deficit Disorder	6.7%
106	Conduct Disorder	6.7%
107	Social Communication Disorder	6.7%
108	Psychological Trauma	6.7%
109	Hoarding Disorder	6.7%
110	Phonological Disorder	6.7%
111	Neonatal Abstinence Syndrome	5.3%
112	Dyspareunia	5%
113	Mutism	4.9%
114	Selective Mutism	4.9%
115	Autistic Disorder	4.9%
116	Asperger Syndrome	4.9%
117	Psychoses, Alcoholic	4.6%
118	Alcohol Use Disorder	4.4%
119	Alcoholic Intoxication	4.4%
120	Heroin Dependence	4.4%
121	Morphine Dependence	4.4%
122	Alcohol abuse	4.4%
123	Sleep Talking	4.4%
124	Sleep Disorders, Intrinsic	4.4%
125	Kluver-Bucy Syndrome	4.4%
126	Consciousness Disorders	4.1%
127	Mental Retardation	4.1%
128	Depressed Level of Consciousness	4.1%
129	Mental deficiency	4.1%
130	Intellectual Disability	4.1%
131	Enuresis	4%
132	Amnesia	4%
133	Delirium	4%
134	Dissociative Amnesia	4%
135	Global Amnesia	4%
136	Restless Legs Syndrome	4%
137	Alcohol Withdrawal Delirium	3.8%
138	Sleep Bruxism	3.3%
139	Presenile dementia	3.3%
140	Senile dementia	3.3%
141	Binge Drinking	3.3%
142	Huntington Disease	3.3%
143	Creutzfeldt-Jakob disease	3.3%
144	Disorders of Excessive Somnolence	3.3%
145	Sleep Initiation and Maintenance Disorders	3.3%
146	Night Terrors	3.3%
147	Somnambulism	3.3%
148	Transient Insomnia	3.3%
149	Sleep Paralysis	3.3%
150	Chronic Insomnia	3.3%
151	REM Sleep Behavior Disorder	3.3%
152	Hypersomnia	3.3%
153	Dyscalculia	3.2%
154	Alexia, Pure	3.2%
155	Sleep Disorders, Circadian Rhythm	2.8%
156	Narcolepsy	2.7%
157	Kleine-Levin Syndrome	2.7%
158	Pick Disease of the Brain	2.7%
159	Sleep Deprivation	2.6%
160	Diurnal Enuresis	2.6%
161	Retrograde amnesia	2.6%
162	Amnesia, Anterograde	2.6%
163	Cataplexy	2.4%
164	Lewy Body Disease	2.2%
165	Wernicke Encephalopathy	2.2%
166	AIDS Dementia Complex	2.2%
167	Amnesia, Transient Global	2.2%
168	Alexia	2.1%
169	Dyslexia	2.1%
170	Frontotemporal dementia	1.9%
171	Auditory Perceptual Disorders	1.9%
172	Jet Lag Syndrome	1.7%
173	Dementia, Vascular	1.6%

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