MetaADEDB 2.0 @ LMMD
Carbidopa
(TZFNLOMSOLWIDK-JTQLQIEISA-N)
Structure
SMILES
NN[C@](C(=O)O)(Cc1ccc(c(c1)O)O)C
Type(s)
Approved
Molecular Formula:
C10H14N2O4
Molecular Weight:
226.229
Log P:
1.0381
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
5
TPSA:
115.81
CAS Number(s):
28860-95-9
Synonym(s)
1.
Carbidopa
2.
Methyldopahydrazine
3.
Carbidopa, (R)-Isomer
4.
Carbidopa, (S)-Isomer
5.
Lodosin
6.
Lodosyn
7.
MK-485
8.
MK-486
9.
MK 485
10.
MK 486
11.
MK485
12.
MK486
External Link(s)
MeSHD002230
PubChem Compound34359
28082766
BindingDB50418773
50346881
ChEBI39585
CHEMBLCHEMBL1201236
DrugBankDB00190
DrugCentral496
IUPHAR/BPS Guide to PHARMACOLOGY5159
KEGGdr:D00558
Therapeutic Target DatabaseD0P7JZ
ZINC19168887
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1NauseaFAERS: 24834974CTD
OFFSIDES
SIDER
US FAERS
2Cerebrovascular accidentFAERS: 1US FAERS
3Drug effect incompleteFAERS: 1US FAERS
4Drug ineffectiveFAERS: 1OFFSIDES
US FAERS
5DysgeusiaFAERS: 1US FAERS
6Intestinal PerforationFAERS: 1US FAERS
7Musculoskeletal stiffnessFAERS: 1US FAERS
8No adverse eventFAERS: 1US FAERS
9Obsessive-Compulsive DisorderFAERS: 1US FAERS
10PeritonitisFAERS: 1US FAERS
11PneumoniaFAERS: 1US FAERS
12TremorFAERS: 13670563CTD
SIDER
US FAERS
13Wrong technique in product usage processFAERS: 1US FAERS
14Abdominal PainSIDER
15AbuseOFFSIDES
16Acute Coronary SyndromeSIDER
17Acute prerenal failureOFFSIDES
18AdenocarcinomaOFFSIDES
19AdenomaOFFSIDES
20AgitationSIDER
21AgranulocytosisSIDER
22AlopeciaSIDER
23AmphetaminesOFFSIDES
24Anemia, Hemolytic466061CTD
25AngioedemaSIDER
26AnorexiaSIDER
27AnxietyOFFSIDES
SIDER
28AphoniaOFFSIDES
29AstheniaOFFSIDES
SIDER
30AtaxiaSIDER
31AthetosisOFFSIDES
32Back PainSIDER
33BlepharospasmSIDER
34Blood GlucoseOFFSIDES
35Blood cholesterolOFFSIDES
36Blood creatine increasedOFFSIDES
37Blood creatinine increasedSIDER
38Blood electrolytes abnormalOFFSIDES
39Blood glucose decreasedOFFSIDES
40Blood potassium decreasedOFFSIDES
41Blood sodium increasedOFFSIDES
42Blood urea increasedSIDER
43Brain Diseases1389541CTD
44BronchitisOFFSIDES
45BruxismSIDER
46Burning tongueSIDER
47CalcinosisOFFSIDES
48Catalepsy12711835
15332494		CTD
49Catatonia11980384CTD
50Cerebral atrophyOFFSIDES
51Chemical and Drug Induced Liver Injury28437613CTD
52Chest PainSIDER
53Choking sensationOFFSIDES
54ChoreaSIDER
55Chronic Obstructive Airway DiseaseOFFSIDES
56Circumstance or information capable of leading to medication errorOFFSIDES
57ColitisOFFSIDES
58Colon adenomaOFFSIDES
59Common ColdSIDER
60Congenital tricuspid valve incompetenceOFFSIDES
61ConstipationSIDER
62Cor pulmonaleOFFSIDES
63DementiaSIDER
64Depression suicidalSIDER
65DermatitisSIDER
66Diabetes mellitus inadequate controlOFFSIDES
67DiplopiaSIDER
68DiscomfortSIDER
69DisorientationSIDER
70DistressSIDER
71Disturbance in sexual arousalSIDER
72DizzinessOFFSIDES
SIDER
73Dopamine dysregulation syndromeOFFSIDES
74Drug administration errorOFFSIDES
75Drug screen negativeOFFSIDES
76Drug toxicityOFFSIDES
77Dry skinOFFSIDES
78Duodenal UlcerSIDER
79Dyskinesia, Drug-Induced2611764
18717735		CTD
80DyspepsiaSIDER
81DysphoniaSIDER
82Emotional distressSIDER
83Endodontic procedureOFFSIDES
84Eosinophilic PneumoniaOFFSIDES
85Euphoric moodSIDER
86FatigueSIDER
87Feeling abnormalSIDER
88FlatulenceSIDER
89FlushingSIDER
90Food cravingOFFSIDES
91Gastrointestinal PainSIDER
92General physical health deteriorationOFFSIDES
93GoiterOFFSIDES
94Hallucinations12355682CTD
95Hay feverOFFSIDES
96HeadacheSIDER
97HeartburnSIDER
98HoarsenessSIDER
99HypersensitivitySIDER
100Hypokinesia3670563CTD
101Hypotension788908CTD
SIDER
102Impaired driving abilityOFFSIDES
103Infusion site mobility decreasedOFFSIDES
104Intention tremorOFFSIDES
105Intervertebral Disc DegenerationOFFSIDES
106LeukopeniaSIDER
107MalaiseSIDER
108Maxillofacial operationOFFSIDES
109Memory impairmentSIDER
110Motor retardationOFFSIDES
111Multiple SclerosisOFFSIDES
112Muscle Rigidity3670563CTD
113Muscle WeaknessOFFSIDES
114Musculoskeletal PainSIDER
115MydriasisSIDER
116Myocardial InfarctionSIDER
117Myoclonus2986413
6997735		CTD
118NasopharyngitisSIDER
119NervousnessSIDER
120Neuroleptic Malignant SyndromeSIDER
121NumbnessSIDER
122Oculogyric crisisSIDER
123Open woundOFFSIDES
124Oral fungal infectionOFFSIDES
125OsteomyelitisOFFSIDES
126PainOFFSIDES
SIDER
127PalpitationsSIDER
128Panic DisorderOFFSIDES
129Parkinson Disease

View details

52131
335094
1104406
6497767
7566641
12355682
16476809
20686159
 		CTD
130Parkinsonian Disorders2611764
4834974
23206800		CTD
131PemphigusSIDER
132Periodontal infectionOFFSIDES
133Periodontal operationOFFSIDES
134Perirectal abscessOFFSIDES
135Pharmaceutical product complaintOFFSIDES
136PhlebitisSIDER
137PolyuriaOFFSIDES
138Post procedural complicationOFFSIDES
139Post procedural discomfortOFFSIDES
140Post procedural infectionOFFSIDES
141PriapismSIDER
142Productive CoughOFFSIDES
143PruritusSIDER
144RetrocollisOFFSIDES
145RhinitisSIDER
146Seizures10744342CTD
147ShockSIDER
148Shoulder PainSIDER
149Sinus bradycardiaOFFSIDES
150Sinus polypOFFSIDES
151SinusitisOFFSIDES
152SomnolenceSIDER
153StaringOFFSIDES
154Stem cell transplantOFFSIDES
155SubileusOFFSIDES
156Substance Withdrawal Syndrome10744342CTD
157SyncopeSIDER
158TensionSIDER
159Therapeutic product ineffectiveOFFSIDES
160ThrombocytopeniaSIDER
161Tooth ExtractionOFFSIDES
162TrismusSIDER
163Urinary IncontinenceSIDER
164Urinary RetentionSIDER
165Urinary tract infectionSIDER
166UrticariaSIDER
167Vomiting4834974CTD
SIDER
168Vulvovaginal mycotic infectionOFFSIDES
169Weight GainOFFSIDES
170Weight decreasedSIDER
171White blood cell count decreasedSIDER
172Wrong drug administeredOFFSIDES
173choreiformSIDER
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