aripiprazole lauroxil
(DDINXHAORAAYAD-UHFFFAOYSA-N)
Structure
- SMILES
- CCCCCCCCCCCC(=O)OCN1C(=O)CCc2c1cc(OCCCCN1CCN(CC1)c1cccc(c1Cl)Cl)cc2
- Type(s)
- Approved; Investigational
- Molecular Formula:
- C36H51Cl2N3O4
- Molecular Weight:
- 660.714
- Log P:
- 8.7433
- Hydrogen Bond Acceptor:
- 7
- Hydrogen Bond Donor:
- 0
- TPSA:
- 62.32
- CAS Number(s):
- 1259305-29-7
Synonym(s)
1.
aripiprazole lauroxil
2.
Aristada
External Link(s)
| MeSH | C000603935 |
| PubChem Compound | 49831411 |
| ChEBI | 90930 |
| CHEMBL | CHEMBL2219425 |
| DrugBank | DB14185 |
| DrugCentral | 5052 |
| KEGG | dr:D10364 |
| ZINC | 95564895 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Injection site pain | FAERS: 143 | US FAERS | |
| 2 | Needle issue | FAERS: 141 | US FAERS | |
| 3 | Drug ineffective | FAERS: 71 | US FAERS | |
| 4 | Injection site mass | FAERS: 47 | US FAERS | |
| 5 | Drug dose omission | FAERS: 45 | US FAERS | |
| 6 | Anxiety | FAERS: 37 | US FAERS | |
| 7 | Fatigue | FAERS: 36 | US FAERS | |
| 8 | Drug administration error | FAERS: 33 | US FAERS | |
| 9 | Syringe issue | FAERS: 33 | US FAERS | |
| 10 | Somnolence | FAERS: 27 | US FAERS | |
| 11 | Agitation | FAERS: 26 | US FAERS | |
| 12 | Feeling abnormal | FAERS: 26 | US FAERS | |
| 13 | Nausea | FAERS: 26 | US FAERS | |
| 14 | Inappropriate schedule of drug administration | FAERS: 23 | US FAERS | |
| 15 | Malaise | FAERS: 23 | US FAERS | |
| 16 | Product administered at inappropriate site | FAERS: 23 | US FAERS | |
| 17 | Schizophrenia | FAERS: 21 | US FAERS | |
| 18 | Tremor | FAERS: 21 | US FAERS | |
| 19 | Drug administered at inappropriate site | FAERS: 20 | US FAERS | |
| 20 | Akathisia | FAERS: 19 | US FAERS | |
| 21 | Paranoia | FAERS: 19 | US FAERS | |
| 22 | Restlessness | FAERS: 19 | US FAERS | |
| 23 | Headache | FAERS: 18 | US FAERS | |
| 24 | Dizziness | FAERS: 17 | US FAERS | |
| 25 | Pregnancy | FAERS: 17 | US FAERS | |
| 26 | Injection site discomfort | FAERS: 15 | US FAERS | |
| 27 | Vomiting | FAERS: 15 | US FAERS | |
| 28 | Inappropriate schedule of product administration | FAERS: 14 | US FAERS | |
| 29 | Product dose omission | FAERS: 14 | US FAERS | |
| 30 | Anger | FAERS: 12 | US FAERS | |
| 31 | Injection site bruising | FAERS: 12 | US FAERS | |
| 32 | Psychiatric decompensation | FAERS: 12 | US FAERS | |
| 33 | Depressed mood | FAERS: 11 | US FAERS | |
| 34 | Incorrect route of drug administration | FAERS: 11 | US FAERS | |
| 35 | Pain | FAERS: 11 | US FAERS | |
| 36 | Stress | FAERS: 11 | US FAERS | |
| 37 | Weight decreased | FAERS: 10 | US FAERS | |
| 38 | Memory impairment | FAERS: 9 | US FAERS | |
| 39 | Wrong technique in product usage process | FAERS: 9 | US FAERS | |
| 40 | Apathy | FAERS: 8 | US FAERS | |
| 41 | Drug abuse | FAERS: 8 | US FAERS | |
| 42 | Injection Site Reaction | FAERS: 8 | US FAERS | |
| 43 | Injection site erythema | FAERS: 8 | US FAERS | |
| 44 | Product use issue | FAERS: 8 | US FAERS | |
| 45 | Unevaluable event | FAERS: 8 | US FAERS | |
| 46 | Arthralgia | FAERS: 7 | US FAERS | |
| 47 | Hypersomnia | FAERS: 7 | US FAERS | |
| 48 | Liquid product physical issue | FAERS: 7 | US FAERS | |
| 49 | Asthenia | FAERS: 6 | US FAERS | |
| 50 | Back Pain | FAERS: 6 | US FAERS | |
| 51 | Middle insomnia | FAERS: 6 | US FAERS | |
| 52 | Nasopharyngitis | FAERS: 6 | US FAERS | |
| 53 | Product quality issue | FAERS: 6 | US FAERS | |
| 54 | Completed Suicide | FAERS: 5 | US FAERS | |
| 55 | Drug screen positive | FAERS: 5 | US FAERS | |
| 56 | Emotional disorder | FAERS: 5 | US FAERS | |
| 57 | Injection site nodule | FAERS: 5 | US FAERS | |
| 58 | Injection site warmth | FAERS: 5 | US FAERS | |
| 59 | Obsessive-Compulsive Disorder | FAERS: 5 | US FAERS | |
| 60 | Alopecia | FAERS: 4 | US FAERS | |
| 61 | Blood glucose decreased | FAERS: 4 | US FAERS | |
| 62 | Compulsive shopping | FAERS: 4 | US FAERS | |
| 63 | Discomfort | FAERS: 4 | US FAERS | |
| 64 | Emotional distress | FAERS: 4 | US FAERS | |
| 65 | Frustration tolerance decreased | FAERS: 4 | US FAERS | |
| 66 | Hostility | FAERS: 4 | US FAERS | |
| 67 | Hypersensitivity | FAERS: 4 | US FAERS | |
| 68 | Injection site indentation | FAERS: 4 | US FAERS | |
| 69 | Injection site inflammation | FAERS: 4 | US FAERS | |
| 70 | Product administration error | FAERS: 4 | US FAERS | |
| 71 | Psychotic symptom | FAERS: 4 | US FAERS | |
| 72 | Restless Legs Syndrome | FAERS: 4 | US FAERS | |
| 73 | Suicide attempt | FAERS: 4 | US FAERS | |
| 74 | Syncope | FAERS: 4 | US FAERS | |
| 75 | Urticaria | FAERS: 4 | US FAERS | |
| 76 | Abdominal Pain | FAERS: 3 | US FAERS | |
| 77 | Accidental exposure to product | FAERS: 3 | US FAERS | |
| 78 | Arthropod bite | FAERS: 3 | US FAERS | |
| 79 | Blood glucose abnormal | FAERS: 3 | US FAERS | |
| 80 | Blood glucose increased | FAERS: 3 | US FAERS | |
| 81 | Blood prolactin increased | FAERS: 3 | US FAERS | |
| 82 | Chromaturia | FAERS: 3 | US FAERS | |
| 83 | Constipation | FAERS: 3 | US FAERS | |
| 84 | Crying | FAERS: 3 | US FAERS | |
| 85 | Drug effect incomplete | FAERS: 3 | US FAERS | |
| 86 | Erectile dysfunction | FAERS: 3 | US FAERS | |
| 87 | Euphoric mood | FAERS: 3 | US FAERS | |
| 88 | Head discomfort | FAERS: 3 | US FAERS | |
| 89 | Hypophagia | FAERS: 3 | US FAERS | |
| 90 | Incontinence | FAERS: 3 | US FAERS | |
| 91 | Injection site irritation | FAERS: 3 | US FAERS | |
| 92 | Injection site pruritus | FAERS: 3 | US FAERS | |
| 93 | Intrusive thoughts | FAERS: 3 | US FAERS | |
| 94 | Joint swelling | FAERS: 3 | US FAERS | |
| 95 | Lack of injection site rotation | FAERS: 3 | US FAERS | |
| 96 | Lethargy | FAERS: 3 | US FAERS | |
| 97 | Loss of personal independence in daily activities | FAERS: 3 | US FAERS | |
| 98 | Mental impairment | FAERS: 3 | US FAERS | |
| 99 | Mood swings | FAERS: 3 | US FAERS | |
| 100 | Musculoskeletal stiffness | FAERS: 3 | US FAERS | |
| 101 | Myalgia | FAERS: 3 | US FAERS | |
| 102 | Nervousness | FAERS: 3 | US FAERS | |
| 103 | No adverse event | FAERS: 3 | US FAERS | |
| 104 | Pneumonia | FAERS: 3 | US FAERS | |
| 105 | Product preparation error | FAERS: 3 | US FAERS | |
| 106 | Product storage error | FAERS: 3 | US FAERS | |
| 107 | Pruritus | FAERS: 3 | US FAERS | |
| 108 | Skin irritation | FAERS: 3 | US FAERS | |
| 109 | Soliloquy | FAERS: 3 | US FAERS | |
| 110 | Tachyphrenia | FAERS: 3 | US FAERS | |
| 111 | Wrong device used | FAERS: 3 | US FAERS | |
| 112 | Wrong product administered | FAERS: 3 | US FAERS | |
| 113 | Abdominal discomfort | FAERS: 2 | US FAERS | |
| 114 | Adverse event | FAERS: 2 | US FAERS | |
| 115 | Ageusia | FAERS: 2 | US FAERS | |
| 116 | Alcohol abuse | FAERS: 2 | US FAERS | |
| 117 | Amnesia | FAERS: 2 | US FAERS | |
| 118 | Blood cholesterol increased | FAERS: 2 | US FAERS | |
| 119 | Blood triglycerides increased | FAERS: 2 | US FAERS | |
| 120 | Bone pain | FAERS: 2 | US FAERS | |
| 121 | Burning sensation | FAERS: 2 | US FAERS | |
| 122 | Catatonia | FAERS: 2 | US FAERS | |
| 123 | Compulsive sexual behaviour | FAERS: 2 | US FAERS | |
| 124 | Conduct Disorder | FAERS: 2 | US FAERS | |
| 125 | Dehydration | FAERS: 2 | US FAERS | |
| 126 | Delusional disorder, unspecified type | FAERS: 2 | US FAERS | |
| 127 | Disorientation | FAERS: 2 | US FAERS | |
| 128 | Emotional poverty | FAERS: 2 | US FAERS | |
| 129 | Erythema | FAERS: 2 | US FAERS | |
| 130 | Flat affect | FAERS: 2 | US FAERS | |
| 131 | Gastroenteritis | FAERS: 2 | US FAERS | |
| 132 | General physical health deterioration | FAERS: 2 | US FAERS | |
| 133 | Hallucinations, mixed | FAERS: 2 | US FAERS | |
| 134 | Hunger | FAERS: 2 | US FAERS | |
| 135 | Hyperphagia | FAERS: 2 | US FAERS | |
| 136 | Impatience | FAERS: 2 | US FAERS | |
| 137 | Incorrect dose administered | FAERS: 2 | US FAERS | |
| 138 | Incorrect drug administration duration | FAERS: 2 | US FAERS | |
| 139 | Incorrect route of product administration | FAERS: 2 | US FAERS | |
| 140 | Infection | FAERS: 2 | US FAERS | |
| 141 | Influenza | FAERS: 2 | US FAERS | |
| 142 | Lack of administration site rotation | FAERS: 2 | US FAERS | |
| 143 | Lymphadenopathy | FAERS: 2 | US FAERS | |
| 144 | Malabsorption from injection site | FAERS: 2 | US FAERS | |
| 145 | Mental status changes | FAERS: 2 | US FAERS | |
| 146 | Musculoskeletal discomfort | FAERS: 2 | US FAERS | |
| 147 | Myocardial Infarction | FAERS: 2 | US FAERS | |
| 148 | Neuroleptic Malignant Syndrome | FAERS: 2 | US FAERS | |
| 149 | Pallor | FAERS: 2 | US FAERS | |
| 150 | Palpitations | FAERS: 2 | US FAERS | |
| 151 | Personality Change | FAERS: 2 | US FAERS | |
| 152 | Product expiration date issue | FAERS: 2 | US FAERS | |
| 153 | Product lot number issue | FAERS: 2 | US FAERS | |
| 154 | Product packaging issue | FAERS: 2 | US FAERS | |
| 155 | Psychiatric symptom | FAERS: 2 | US FAERS | |
| 156 | Sciatica | FAERS: 2 | US FAERS | |
| 157 | Sluggishness | FAERS: 2 | US FAERS | |
| 158 | Taciturnity | FAERS: 2 | US FAERS | |
| 159 | Tardive Dyskinesia | FAERS: 2 | US FAERS | |
| 160 | Therapy non-responder | FAERS: 2 | US FAERS | |
| 161 | Thirst | FAERS: 2 | US FAERS | |
| 162 | Thrombosis | FAERS: 2 | US FAERS | |
| 163 | Trismus | FAERS: 2 | US FAERS | |
| 164 | Vertigo | FAERS: 2 | US FAERS | |
| 165 | Violence-related symptom | FAERS: 2 | US FAERS | |
| 166 | Wrong drug administered | FAERS: 2 | US FAERS | |
| 167 | Acarodermatitis | FAERS: 1 | US FAERS | |
| 168 | Accidental underdose | FAERS: 1 | US FAERS | |
| 169 | Acne | FAERS: 1 | US FAERS | |
| 170 | Adnexa uteri pain | FAERS: 1 | US FAERS | |
| 171 | Anaphylactic shock | FAERS: 1 | US FAERS | |
| 172 | Angina Pectoris | FAERS: 1 | US FAERS | |
| 173 | Anorgasmia | FAERS: 1 | US FAERS | |
| 174 | Antipsychotic drug level increased | FAERS: 1 | US FAERS | |
| 175 | Aphonia | FAERS: 1 | US FAERS | |
| 176 | Back disorder | FAERS: 1 | US FAERS | |
| 177 | Belligerence | FAERS: 1 | US FAERS | |
| 178 | Blood potassium decreased | FAERS: 1 | US FAERS | |
| 179 | Blood prolactin decreased | FAERS: 1 | US FAERS | |
| 180 | Blood thyroid stimulating hormone increased | FAERS: 1 | US FAERS | |
| 181 | Bradycardia | FAERS: 1 | US FAERS | |
| 182 | Bradykinesia | FAERS: 1 | US FAERS | |
| 183 | Bronchitis | FAERS: 1 | US FAERS | |
| 184 | Caffeine consumption | FAERS: 1 | US FAERS | |
| 185 | Cervix carcinoma | FAERS: 1 | US FAERS | |
| 186 | Chest discomfort | FAERS: 1 | US FAERS | |
| 187 | Chills | FAERS: 1 | US FAERS | |
| 188 | Conjunctivitis | FAERS: 1 | US FAERS | |
| 189 | Death of companion | FAERS: 1 | US FAERS | |
| 190 | Delusional disorder, grandiose type | FAERS: 1 | US FAERS | |
| 191 | Dependence | FAERS: 1 | US FAERS | |
| 192 | Diabetes Mellitus | FAERS: 1 | US FAERS | |
| 193 | Disease recurrence | FAERS: 1 | US FAERS | |
| 194 | Dissociation | FAERS: 1 | US FAERS | |
| 195 | Disturbance in sexual arousal | FAERS: 1 | US FAERS | |
| 196 | Drug administered to patient of inappropriate age | FAERS: 1 | US FAERS | |
| 197 | Drug level decreased | FAERS: 1 | US FAERS | |
| 198 | Dysarthria | FAERS: 1 | US FAERS | |
| 199 | Dyspepsia | FAERS: 1 | US FAERS | |
| 200 | Dystonia | FAERS: 1 | US FAERS | |
| 201 | Eating disorder symptom | FAERS: 1 | US FAERS | |
| 202 | Economic problem | FAERS: 1 | US FAERS | |
| 203 | Educational problem | FAERS: 1 | US FAERS | |
| 204 | Egocentrism | FAERS: 1 | US FAERS | |
| 205 | Enuresis | FAERS: 1 | US FAERS | |
| 206 | Excessive masturbation | FAERS: 1 | US FAERS | |
| 207 | Feeling jittery | FAERS: 1 | US FAERS | |
| 208 | Feelings of worthlessness | FAERS: 1 | US FAERS | |
| 209 | Flushing | FAERS: 1 | US FAERS | |
| 210 | Foaming at mouth | FAERS: 1 | US FAERS | |
| 211 | Food Poisoning | FAERS: 1 | US FAERS | |
| 212 | Formication | FAERS: 1 | US FAERS | |
| 213 | Gait inability | FAERS: 1 | US FAERS | |
| 214 | Hepatitis C | FAERS: 1 | US FAERS | |
| 215 | Homicide | FAERS: 1 | US FAERS | |
| 216 | Hypomania | FAERS: 1 | US FAERS | |
| 217 | Hypotension | FAERS: 1 | US FAERS | |
| 218 | Impaired reasoning | FAERS: 1 | US FAERS | |
| 219 | Impaired self-care | FAERS: 1 | US FAERS | |
| 220 | Impaired work ability | FAERS: 1 | US FAERS | |
| 221 | Inappropriate affect | FAERS: 1 | US FAERS | |
| 222 | Incoherent | FAERS: 1 | US FAERS | |
| 223 | Induration | FAERS: 1 | US FAERS | |
| 224 | Inflammation | FAERS: 1 | US FAERS | |
| 225 | Injection site cellulitis | FAERS: 1 | US FAERS | |
| 226 | Injection site extravasation | FAERS: 1 | US FAERS | |
| 227 | Injection site nerve damage | FAERS: 1 | US FAERS | |
| 228 | Injection site scab | FAERS: 1 | US FAERS | |
| 229 | Injection site urticaria | FAERS: 1 | US FAERS | |
| 230 | Injection site vesicles | FAERS: 1 | US FAERS | |
| 231 | Injury associated with device | FAERS: 1 | US FAERS | |
| 232 | Intentional self-injury | FAERS: 1 | US FAERS | |
| 233 | Intestinal Obstruction | FAERS: 1 | US FAERS | |
| 234 | Irregular sleep wake rhythm disorder | FAERS: 1 | US FAERS | |
| 235 | Lack of spontaneous speech | FAERS: 1 | US FAERS | |
| 236 | Limb discomfort | FAERS: 1 | US FAERS | |
| 237 | Limb injury | FAERS: 1 | US FAERS | |
| 238 | Lip swelling | FAERS: 1 | US FAERS | |
| 239 | Lymphoma | FAERS: 1 | US FAERS | |
| 240 | Maternal exposure timing unspecified | FAERS: 1 | US FAERS | |
| 241 | Medication dilution | FAERS: 1 | US FAERS | |
| 242 | Menorrhagia | FAERS: 1 | US FAERS | |
| 243 | Muscle strain | FAERS: 1 | US FAERS | |
| 244 | Muscle tightness | FAERS: 1 | US FAERS | |
| 245 | Negative thoughts | FAERS: 1 | US FAERS | |
| 246 | Nephrolithiasis | FAERS: 1 | US FAERS | |
| 247 | Neutrophil count decreased | FAERS: 1 | US FAERS | |
| 248 | Night sweats | FAERS: 1 | US FAERS | |
| 249 | Obsessive thoughts | FAERS: 1 | US FAERS | |
| 250 | Oropharyngeal pain | FAERS: 1 | US FAERS | |
| 251 | Overdose | FAERS: 1 | US FAERS | |
| 252 | Paranoid Personality Disorder | FAERS: 1 | US FAERS | |
| 253 | Pelvic Pain | FAERS: 1 | US FAERS | |
| 254 | Peripheral swelling | FAERS: 1 | US FAERS | |
| 255 | Personal relationship issue | FAERS: 1 | US FAERS | |
| 256 | Pneumothorax | FAERS: 1 | US FAERS | |
| 257 | Polydipsia | FAERS: 1 | US FAERS | |
| 258 | Poor personal hygiene | FAERS: 1 | US FAERS | |
| 259 | Poor quality drug administered | FAERS: 1 | US FAERS | |
| 260 | Poor quality sleep | FAERS: 1 | US FAERS | |
| 261 | Post-Traumatic Stress Disorder | FAERS: 1 | US FAERS | |
| 262 | Prescribed overdose | FAERS: 1 | US FAERS | |
| 263 | Product dispensing error | FAERS: 1 | US FAERS | |
| 264 | Product residue present | FAERS: 1 | US FAERS | |
| 265 | Product use complaint | FAERS: 1 | US FAERS | |
| 266 | Renal pain | FAERS: 1 | US FAERS | |
| 267 | Respiratory tract congestion | FAERS: 1 | US FAERS | |
| 268 | Retching | FAERS: 1 | US FAERS | |
| 269 | Rheumatoid Arthritis | FAERS: 1 | US FAERS | |
| 270 | Schizoaffective Disorder | FAERS: 1 | US FAERS | |
| 271 | Screaming | FAERS: 1 | US FAERS | |
| 272 | Seasonal Affective Disorder | FAERS: 1 | US FAERS | |
| 273 | Sepsis | FAERS: 1 | US FAERS | |
| 274 | Sexual Dysfunction | FAERS: 1 | US FAERS | |
| 275 | Sleep Talking | FAERS: 1 | US FAERS | |
| 276 | Somnambulism | FAERS: 1 | US FAERS | |
| 277 | Staring | FAERS: 1 | US FAERS | |
| 278 | Stubbornness | FAERS: 1 | US FAERS | |
| 279 | Swelling | FAERS: 1 | US FAERS | |
| 280 | Therapeutic product effect decreased | FAERS: 1 | US FAERS | |
| 281 | Therapy change | FAERS: 1 | US FAERS | |
| 282 | Therapy partial responder | FAERS: 1 | US FAERS | |
| 283 | Tinnitus | FAERS: 1 | US FAERS | |
| 284 | Tobacco user | FAERS: 1 | US FAERS | |
| 285 | Toothache | FAERS: 1 | US FAERS | |
| 286 | Toxicity to various agents | FAERS: 1 | US FAERS | |
| 287 | Unresponsive to stimuli | FAERS: 1 | US FAERS | |
| 288 | Vaginal Discharge | FAERS: 1 | US FAERS | |
| 289 | Visual brightness | FAERS: 1 | US FAERS | |
| 290 | Walking aid user | FAERS: 1 | US FAERS | |
| 291 | White blood cell count decreased | FAERS: 1 | US FAERS | |
| 292 | Wrong patient received medication | FAERS: 1 | US FAERS | |
| 293 | furuncle | FAERS: 1 | US FAERS |
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