MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Autistic Disorder

(UMLS:C0004352)

Definition:: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)
UMLS ID:: C0004352
MeSH ID:: D001321

Classification:

Name:

Mental Disorders
MeSH Tree Number(s):: F03.625.164.113.500

Synonym(s)

Autistic Disorder

AUTISM

AUTISM INFANTILE

AUTISTIC

Autism

Autism disorder

Autism in children

Autism, childhood onset

Autism;child

10.

Autistic disorder

11.

Autistic disorder of childhood onset

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Aripiprazole	FAERS: 2	17069544	CTD US FAERS
2	Topiramate	FAERS: 1		US FAERS
3	2,2',4,4'-tetrabromodiphenyl ether		19211157	CTD
4	3-(3-hydroxyphenyl)-3-hydroxypropanoic acid		20423563	CTD
5	5-Methylcytosine		25423485	CTD
6	5-hydroxymethylcytosine		25423485	CTD
7	5-methyltetrahydrofolate		18461502	CTD
8	8-oxo-7-hydrodeoxyguanosine		25423485	CTD
9	Acetaminophen		18445737	CTD
10	Adenosine		20468076	CTD
11	Amantadine		19232924	CTD
12	Arachidonic Acid		18582451	CTD
13	Atomoxetine Hydrochloride		19232924	CTD
14	Biopterin		16139734	CTD
15	Buspirone		18056831	CTD
16	Choline		16818868	CTD
17	Citalopram		18775368 19232924	CTD
18	Clomipramine		11476129	CTD
19	Clonidine		1479049	CTD
20	Creatine		16818868	CTD
21	Cyproheptadine		15068403	CTD
22	Cysteine		16917939 19056591 19267885	CTD
23	Dehydroepiandrosterone Sulfate		15820420	CTD
24	Digoxin		14585753	CTD
25	Docosahexaenoic Acids		18582451	CTD
26	Fatty Acids, Omega-3		16920077	CTD
27	Fenfluramine		2606882 3709993 6502317	CTD
28	Fluoxetine		15246500 18775368 19232924	CTD
29	Fluvoxamine		12607287 18775368 19232924	CTD
30	Folic Acid		21388746 24676906	CTD
31	Fursultiamin		12195231	CTD
32	Galantamine		17069550	CTD
33	Glutathione Disulfide		19056591	CTD
34	Glutathione		View details 16917939 18929414 19056591 19267885 24676906	CTD
35	Guanfacine		19232924	CTD
36	Haloperidol		View details 11476129 15068403 18080171 19368416	CTD
37	Homocysteine		16297937 20468076 24676906	CTD
38	Inositol		16818868	CTD
39	Leuprolide		17187010	CTD
40	Levetiracetam		19232924 19265183	CTD
41	Linoleic Acid		18582451	CTD
42	Magnesium		16846101	CTD
43	Melatonin		16897403 16919138	CTD
44	Memantine		17690064	CTD
45	Mercury Compounds		17497416 24676906	CTD
46	Methionine		16917939 19056591 19267885	CTD
47	Methylphenidate		16919137 18752063 19232924	CTD
48	Mirtazapine		16648008	CTD
49	Misoprostol		12806493	CTD
50	Naltrexone		8570775 9028057 19393386	CTD
51	Neopterin		16139734	CTD
52	Norepinephrine		8570775	CTD
53	Olanzapine		17069543 17822346 18685284	CTD
54	Oxytocin		16904652	CTD
55	Pioglitazone		17207275	CTD
56	Piracetam		17929164	CTD
57	Poly I-C		23516405	CTD
58	Propranolol		18766980	CTD
59	Quinolinic Acid		16139734	CTD
60	Risperidone		View details 8768340 9229261 9672054 9808916 10933118 15492353 15543515 15930063 15994720 16239862 16379507 16601648 16730335 16948927 17019624 17069546 17822346 17929164 18026891 18080171 18278980 18349709 18387724 18775368 19013209 19154706 19232924 19368416 19997080 20013426	CTD
61	S-Adenosylhomocysteine		16917939 20468076	CTD
62	S-Adenosylmethionine		16917939 19056591	CTD
63	SAICAR		6150139	CTD
64	Serotonin		View details 8570775 15132762 17157402 18062943 18361446 18405062 19221690	CTD
65	Sertraline		18775368	CTD
66	Sirolimus		21115397	CTD
67	Spironolactone		17150311	CTD
68	Succimer		17187010	CTD
69	Suramin		23516405	CTD
70	Terbutaline		16417856 17400887	CTD
71	Thalidomide		View details 8157157 10360298 15747750 19755133	CTD
72	Thimerosal		18404135 24675092	CTD
73	Valproic Acid		View details 7512516 8808733 9100317 9344057 11263692 15238991 15794725 16609825 17157402 17507914 17688650 18177632 18316065 18396377 18558336 18775368 18940202 18985861 19232924 19460635 19755133 20603192 23665938 29427782 30404997	CTD
74	Vitamin B 12		16297937 24676906	CTD
75	Vitamin B 6		16494569 16846101	CTD
76	cysteinylglycine		19056591	CTD
77	efalex		18582451	CTD
78	phosphinothricin		25477793	CTD
79	propionic acid		18395759	CTD
80	sapropterin		16160627	CTD
81	succinyladenosine		6150139	CTD
82	ziprasidone		18315450	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Asperger Syndrome	48.4%
2	Child Behavior Disorders	25.4%
3	Developmental Disabilities	25.4%
4	Developmental Coordination Disorder	25.4%
5	Head Banging	25.4%
6	Motor Skills Disorders	25.4%
7	Oppositional Defiant Disorder	25.4%
8	Schizophrenia, Childhood	25.4%
9	Stereotypic Movement Disorder	25.4%
10	Attention Deficit and Disruptive Behavior Disorders	25.4%
11	Reactive Attachment Disorder	25.4%
12	Separation Anxiety Disorder	23%
13	Neurotic Disorders	16.9%
14	Anxiety Disorders	16.4%
15	Avoidant Personality Disorder	16.4%
16	Dissociative disorder	16.4%
17	Frigidity	16.4%
18	Hypoactive Sexual Desire Disorder	16.4%
19	Disruptive, Impulse Control, and Conduct Disorders	16.4%
20	Intermittent Explosive Disorder	16.4%
21	Kleptomania	16.4%
22	Narcissistic Personality Disorder	16.4%
23	Personality Disorders	16.4%
24	Sexual Aversion Disorder	16.4%
25	Somatoform Disorder	16.4%
26	Dissociation	16.4%
27	Motor Disorders	16.4%
28	Mood Disorders	16.4%
29	Schizophrenia Spectrum and Other Psychotic Disorders	16.4%
30	Neurocognitive Disorders	16.4%
31	Feeding and Eating Disorders	16.4%
32	Attention Deficit Disorder	14.8%
33	Conduct Disorder	14.8%
34	Social Communication Disorder	14.8%
35	Phonological Disorder	14.8%
36	Mutism	12.2%
37	Selective Mutism	12.2%
38	Drug abuse	11.4%
39	Substance Dependence	11.4%
40	Substance-Related Disorders	11.4%
41	Drug Dependence	11.4%
42	Mental Retardation	10.1%
43	Mental deficiency	10.1%
44	Intellectual Disability	10.1%
45	Adjustment Disorders	8.5%
46	Affective Disorders, Psychotic	8.5%
47	Agoraphobia	8.5%
48	Anorexia Nervosa	8.5%
49	Antisocial Personality Disorder	8.5%
50	Bipolar Disorder	8.5%
51	Body Dysmorphic Disorders	8.5%
52	Borderline Personality Disorder	8.5%
53	Capgras Syndrome	8.5%
54	Claustrophobia	8.5%
55	Cognition Disorders	8.5%
56	Conversion disorder	8.5%
57	Cyclothymic Disorder	8.5%
58	Dependent Personality Disorder	8.5%
59	Depressive disorder	8.5%
60	Exhibitionism	8.5%
61	Factitious Disorders	8.5%
62	Firesetting Behavior	8.5%
63	Histrionic Personality Disorder	8.5%
64	Hypochondriasis	8.5%
65	Masochism	8.5%
66	Melancholia	8.5%
67	Dissociative Identity Disorder	8.5%
68	Neurasthenia	8.5%
69	Obsessive-Compulsive Disorder	8.5%
70	Panic Disorder	8.5%
71	Paranoid Personality Disorder	8.5%
72	Pedophilia	8.5%
73	Pseudodementia	8.5%
74	Psychotic Disorders	8.5%
75	Sadism	8.5%
76	Schizoaffective Disorder	8.5%
77	Schizoid Personality Disorder	8.5%
78	Schizophrenia	8.5%
79	Schizotypal Personality Disorder	8.5%
80	Transvestism	8.5%
81	Trichotillomania	8.5%
82	Voyeurism	8.5%
83	Hyperkinetic Heart Syndrome	8.5%
84	Sexual and Gender Disorders	8.5%
85	Gender Dysphoria	8.5%
86	Paranoia	8.5%
87	Compulsive Personality Disorder	8.5%
88	Bulimia Nervosa	8.5%
89	Sleep Wake Disorders	8.3%
90	Dyscalculia	7.2%
91	Marijuana Abuse	5.7%
92	Opioid-Related Disorders	5.7%
93	Nicotine Dependence	5.7%
94	Opioid abuse	5.7%
95	Parasomnia	5.7%
96	Phencyclidine Abuse	5.7%
97	Substance Abuse, Intravenous	5.7%
98	Substance Withdrawal Syndrome	5.7%
99	Tobacco Use Disorder	5.7%
100	Alcohol-Related Disorders	5.7%
101	Amphetamine-Related Disorders	5.7%
102	Cocaine-Related Disorders	5.7%
103	Dyssomnias	5.7%
104	Gambling	5.6%
105	Premature Ejaculation	5.6%
106	Erectile dysfunction	5.6%
107	Dementia	5.6%
108	Psychoses, Substance-Induced	5.5%
109	Combat Disorders	4.9%
110	Dysthymic Disorder	4.9%
111	Hysteria	4.9%
112	Schizophrenia, Catatonic	4.9%
113	Schizophrenia, Disorganized	4.9%
114	Post-Traumatic Stress Disorder	4.9%
115	Seasonal Affective Disorder	4.9%
116	Psychological Trauma	4.9%
117	Hoarding Disorder	4.9%
118	Alexia	4.8%
119	Dyslexia	4.8%
120	Neonatal Abstinence Syndrome	4.3%
121	Dyspareunia	4.2%
122	Consciousness Disorders	3.4%
123	Depressed Level of Consciousness	3.4%
124	Enuresis	3.3%
125	Amnesia	3.3%
126	Delirium	3.3%
127	Dissociative Amnesia	3.3%
128	Global Amnesia	3.3%
129	Alcohol Use Disorder	3.3%
130	Alcoholic Intoxication	3.3%
131	Heroin Dependence	3.3%
132	Morphine Dependence	3.3%
133	Alcohol abuse	3.3%
134	Depression, Postpartum	3.3%
135	Sleep Talking	3.3%
136	Sleep Disorders, Intrinsic	3.3%
137	Psychoses, Alcoholic	3.3%
138	Kluver-Bucy Syndrome	3.3%
139	Premenstrual Dysphoric Disorder	3.3%
140	Restless Legs Syndrome	2.8%
141	Alcohol Withdrawal Delirium	2.8%
142	Sleep Bruxism	2.5%
143	Presenile dementia	2.5%
144	Senile dementia	2.5%
145	Binge Drinking	2.5%
146	Huntington Disease	2.5%
147	Creutzfeldt-Jakob disease	2.4%
148	Alexia, Pure	2.4%
149	Disorders of Excessive Somnolence	2.2%
150	Sleep Initiation and Maintenance Disorders	2.2%
151	Night Terrors	2.2%
152	Somnambulism	2.2%
153	Transient Insomnia	2.2%
154	Sleep Paralysis	2.2%
155	Chronic Insomnia	2.2%
156	REM Sleep Behavior Disorder	2.2%
157	Hypersomnia	2.2%
158	Sleep Disorders, Circadian Rhythm	2.1%
159	Sleep Deprivation	2%
160	Diurnal Enuresis	1.9%
161	Retrograde amnesia	1.9%
162	Amnesia, Anterograde	1.9%
163	Lewy Body Disease	1.6%
164	Wernicke Encephalopathy	1.6%
165	AIDS Dementia Complex	1.6%
166	Amnesia, Transient Global	1.6%
167	Narcolepsy	1.6%
168	Kleine-Levin Syndrome	1.6%
169	Pick Disease of the Brain	1.6%
170	Auditory Perceptual Disorders	1.4%
171	Cataplexy	1.3%
172	Frontotemporal dementia	1.3%
173	Dementia, Vascular	1.2%
174	Jet Lag Syndrome	1.1%

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