MetaADEDB 2.0 @ LMMD
Doxazosin
(RUZYUOTYCVRMRZ-UHFFFAOYSA-N)
Structure
SMILES
COc1cc2nc(nc(c2cc1OC)N)N1CCN(CC1)C(=O)C1COc2c(O1)cccc2
Type(s)
Approved
ATC code(s)
C02CA04
Molecular Formula:
C23H25N5O5
Molecular Weight:
451.475
Log P:
2.3019
Hydrogen Bond Acceptor:
10
Hydrogen Bond Donor:
1
TPSA:
112.27
CAS Number(s):
74191-85-8
Synonym(s)
1.
Doxazosin
2.
Doxazosin Mesylate
3.
1 (4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl)piperazine
4.
Alfamedin
5.
Apo-Doxazosin
6.
Cardular
7.
Cardura
8.
Carduran
9.
Carduran Neo
10.
Diblocin
11.
Doxa-Puren
12.
DoxaUro
13.
Doxacor
14.
Doxagamma
15.
Doxamax
16.
Doxatensa
17.
Doxazomerck
18.
Doxazosin AL
19.
Doxazosin AZU
20.
Doxazosin Apogepha
21.
Doxazosin Heumann
22.
Doxazosin Klast
23.
Doxazosin Monohydrochloride
24.
Doxazosin Stada
25.
Doxazosin Von Ct
26.
Doxazosin beta
27.
Doxazosin findusFit
28.
Doxazosin-Wolff
29.
Doxazosin-ratiopharm
30.
Doxazosina Alter
31.
Doxazosina Cinfa
32.
Doxazosina Combino Pharm
33.
Doxazosina Geminis
34.
Doxazosina Normon
35.
Doxazosina Pharmagenus
36.
Doxazosina Ratiopharm
37.
Doxazosina Ur
38.
Gen-Doxazosin
39.
Jutalar
40.
MTW-Doxazosin
41.
Novo-Doxazosin
42.
Progandol Neo
43.
UK-33274
44.
Uriduct
45.
Zoxan
46.
ratio-Doxazosin
47.
Apo Doxazosin
48.
Ct, Doxazosin Von
49.
Doxa Puren
50.
Doxazosin Wolff
51.
Doxazosin ratiopharm
52.
Gen Doxazosin
53.
MTW Doxazosin
54.
Mesylate, Doxazosin
55.
Monohydrochloride, Doxazosin
56.
Neo, Carduran
57.
Novo Doxazosin
58.
Ratiopharm, Doxazosina
59.
UK 33274
60.
UK33274
61.
Von Ct, Doxazosin
62.
ratio Doxazosin
External Link(s)
MeSHD017292
PubChem Compound3157
BindingDB50019693
86731
ChEBI4708
CHEMBLCHEMBL707
DrugBankDB00590
DrugCentral954
IUPHAR/BPS Guide to PHARMACOLOGY7170
KEGGcpd:C06970
dr:D07874
Therapeutic Target DatabaseD03MIR
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1DizzinessFAERS: 1910595697CTD
OFFSIDES
SIDER
US FAERS
2Drug ineffectiveFAERS: 19
Canada Vigilance: 2
Canada Vigilance
US FAERS
3SyncopeFAERS: 18SIDER
US FAERS
4HypotensionFAERS: 153023106
11837346
17906163
CTD
SIDER
US FAERS
5Product substitution issueFAERS: 13
Canada Vigilance: 1
Canada Vigilance
US FAERS
6NauseaFAERS: 10SIDER
US FAERS
7UrticariaFAERS: 10SIDER
US FAERS
8FatigueFAERS: 919353415CTD
OFFSIDES
SIDER
US FAERS
9MalaiseFAERS: 7SIDER
US FAERS
10Chest PainFAERS: 6SIDER
US FAERS
11TremorFAERS: 6SIDER
US FAERS
12VomitingFAERS: 6SIDER
US FAERS
13HypersensitivityFAERS: 5SIDER
US FAERS
14Neck PainFAERS: 5US FAERS
15PruritusFAERS: 5SIDER
US FAERS
16SwellingFAERS: 5US FAERS
17Urinary RetentionFAERS: 5
Canada Vigilance: 1
15476515CTD
SIDER
Canada Vigilance
US FAERS
18Cardiac ArrestFAERS: 4US FAERS
19Feeling ColdFAERS: 4US FAERS
20Feeling abnormalFAERS: 4SIDER
US FAERS
21Floppy iris syndromeFAERS: 4OFFSIDES
SIDER
US FAERS
22Livedo ReticularisFAERS: 4OFFSIDES
US FAERS
23Pharmaceutical product complaintFAERS: 4US FAERS
24PneumoniaFAERS: 4SIDER
US FAERS
25Ventricular FibrillationFAERS: 4US FAERS
26ArthralgiaFAERS: 3SIDER
US FAERS
27AstheniaFAERS: 310595697CTD
OFFSIDES
SIDER
US FAERS
28Cerebrovascular accidentFAERS: 3SIDER
US FAERS
29Chest discomfortFAERS: 3US FAERS
30Drug exposure during pregnancyFAERS: 3US FAERS
31DysuriaFAERS: 3OFFSIDES
SIDER
US FAERS
32HeadacheFAERS: 310595697CTD
SIDER
US FAERS
33PancytopeniaFAERS: 3US FAERS
34Acute Coronary SyndromeFAERS: 2SIDER
US FAERS
35AnxietyFAERS: 2SIDER
US FAERS
36Atrial FibrillationFAERS: 2SIDER
US FAERS
37Bladder NeoplasmFAERS: 2US FAERS
38CardiomegalyFAERS: 215969258CTD
US FAERS
39ConstipationFAERS: 2SIDER
US FAERS
40Drug abuseFAERS: 2US FAERS
41DysgeusiaFAERS: 2SIDER
US FAERS
42Malignant neoplasm progressionFAERS: 2US FAERS
43MyalgiaFAERS: 2SIDER
US FAERS
44Myocardial InfarctionFAERS: 2SIDER
US FAERS
45PainFAERS: 216563475CTD
SIDER
US FAERS
46PalpitationsFAERS: 2SIDER
US FAERS
47Product appearance confusionFAERS: 2US FAERS
48Product quality issueFAERS: 2US FAERS
49Urinary IncontinenceFAERS: 29572189
19353415
CTD
SIDER
US FAERS
50Weight decreasedFAERS: 2SIDER
US FAERS
51Wrong technique in product usage processFAERS: 2US FAERS
52Abdominal PainFAERS: 1SIDER
US FAERS
53Accidental overdoseFAERS: 1US FAERS
54AlopeciaFAERS: 1SIDER
US FAERS
55Anal discomfortFAERS: 1OFFSIDES
US FAERS
56Anaphylactic shockFAERS: 1US FAERS
57AngioedemaFAERS: 116957427CTD
US FAERS
58AsthmaFAERS: 1US FAERS
59AuraFAERS: 1US FAERS
60Back PainFAERS: 1SIDER
US FAERS
61Bipolar DisorderFAERS: 1US FAERS
62Blood pressure inadequately controlledFAERS: 1OFFSIDES
US FAERS
63BradyphreniaFAERS: 1US FAERS
64BronchitisFAERS: 1SIDER
US FAERS
65CataractFAERS: 1SIDER
US FAERS
66CryingFAERS: 1US FAERS
67Depressed moodFAERS: 1US FAERS
68DiverticulitisFAERS: 1SIDER
US FAERS
69Drug prescribing errorFAERS: 1US FAERS
70Early satietyFAERS: 1US FAERS
71Erectile dysfunctionFAERS: 1SIDER
US FAERS
72ErythemaFAERS: 1US FAERS
73Expired product administeredFAERS: 1US FAERS
74Gastrointestinal PainFAERS: 1SIDER
US FAERS
75GoutFAERS: 1SIDER
US FAERS
76Hallucinations, mixedFAERS: 1US FAERS
77HypersomniaFAERS: 1US FAERS
78Hypertensive crisisFAERS: 1US FAERS
79IncontinenceFAERS: 1US FAERS
80Increased upper airway secretionFAERS: 1US FAERS
81InfectionFAERS: 1OFFSIDES
SIDER
US FAERS
82InfluenzaFAERS: 1US FAERS
83IridoceleFAERS: 1US FAERS
84LethargyFAERS: 1US FAERS
85Lip swellingFAERS: 1US FAERS
86Mental status changesFAERS: 1US FAERS
87Musculoskeletal PainFAERS: 1US FAERS
88Musculoskeletal chest painFAERS: 1US FAERS
89Musculoskeletal stiffnessFAERS: 1OFFSIDES
US FAERS
90NephrectomyFAERS: 1OFFSIDES
US FAERS
91Orgasmic sensation decreasedFAERS: 1US FAERS
92Orthostatic intoleranceFAERS: 1US FAERS
93Peripheral swellingFAERS: 1US FAERS
94Poor quality sleepFAERS: 1US FAERS
95Procedural complicationFAERS: 1US FAERS
96Product counterfeitFAERS: 1US FAERS
97Productive CoughFAERS: 1OFFSIDES
US FAERS
98ProstatectomyFAERS: 1US FAERS
99Pulmonary FibrosisFAERS: 1US FAERS
100Reaction to excipientFAERS: 1US FAERS
101SomnambulismFAERS: 1US FAERS
102SomnolenceFAERS: 1SIDER
US FAERS
103Spontaneous penile erectionFAERS: 1US FAERS
104TachycardiaFAERS: 1SIDER
US FAERS
105ThrombocytopeniaFAERS: 1SIDER
US FAERS
106Unevaluable eventFAERS: 1US FAERS
107Unresponsive to stimuliFAERS: 1US FAERS
108Urinary tract infectionFAERS: 1SIDER
US FAERS
109prostatitisFAERS: 1US FAERS
110treatment failureFAERS: 1US FAERS
111AbasiaOFFSIDES
112Abdominal AbscessOFFSIDES
113Abdominal discomfortOFFSIDES
SIDER
114Abdominal strangulated herniaOFFSIDES
115Abnormal visionSIDER
116AbscessOFFSIDES
117AcidosisOFFSIDES
118Actinic keratosisOFFSIDES
119ActinomycosisOFFSIDES
120AdenocarcinomaOFFSIDES
121AdenomaOFFSIDES
122AgitationSIDER
123Albuminuria15921073CTD
124Altered state of consciousnessOFFSIDES
125AlveolitisOFFSIDES
126AmnesiaSIDER
127AmyloidosisOFFSIDES
128Anastomotic complicationOFFSIDES
129AneurysmSIDER
130Angina PectorisSIDER
131AnhedoniaOFFSIDES
132Anorectal discomfortSIDER
133AnorexiaOFFSIDES
SIDER
134Aortic valve sclerosisOFFSIDES
135ApathyOFFSIDES
SIDER
136ArteriosclerosisOFFSIDES
137ArthritisSIDER
138Aspiration PneumoniaOFFSIDES
139AtaxiaSIDER
140AtelectasisOFFSIDES
141Atrial FlutterOFFSIDES
142Atrial thrombosisOFFSIDES
143Atrioventricular BlockOFFSIDES
144BelligerenceOFFSIDES
145Benign Prostatic HyperplasiaOFFSIDES
146Benign biliary neoplasmOFFSIDES
147Bladder painSIDER
148Blood creatine increasedOFFSIDES
149Blood creatinine increasedOFFSIDES
150Blood glucose decreasedOFFSIDES
151Blood magnesium decreasedOFFSIDES
152Blood phosphorus increasedOFFSIDES
153Blood potassium increasedOFFSIDES
154Blood sodiumOFFSIDES
155Blood urea increasedOFFSIDES
156BradycardiaOFFSIDES
SIDER
157BronchiolitisOFFSIDES
158Bronchospasm aggravatedSIDER
159BronchospasmSIDER
160Carcinoma of lungSIDER
161CarcinomaSIDER
162CardiotoxicityOFFSIDES
163Carotid bruitOFFSIDES
164Cerebellar AtaxiaOFFSIDES
165ChillsSIDER
166CholelithiasisSIDER
167CholestasisSIDER
168ChromaturiaOFFSIDES
169Chromosome Aberrations22015851CTD
170Chronic Obstructive Airway DiseaseOFFSIDES
171Chronic sinusitisOFFSIDES
172Colon adenomaOFFSIDES
173Concomitant disease aggravatedOFFSIDES
174Congenital tricuspid valve incompetenceOFFSIDES
175ConjunctivitisSIDER
176ContractureOFFSIDES
177Coronary artery insufficiencyOFFSIDES
178Cramps of lower extremitiesSIDER
179Creatinine renal clearance decreasedOFFSIDES
180CystitisSIDER
181DeafnessSIDER
182DehydrationOFFSIDES
SIDER
183Dental abscessOFFSIDES
184Depressed Level of ConsciousnessOFFSIDES
185DermatitisSIDER
186DiabetesOFFSIDES
187DiarrheaOFFSIDES
188Diastolic dysfunctionOFFSIDES
189DiplopiaSIDER
190DiscomfortSIDER
191Disseminated Intravascular CoagulationOFFSIDES
192Disturbance in sexual arousalSIDER
193Diverticular perforationOFFSIDES
194DiverticulosisOFFSIDES
195DiverticulumOFFSIDES
196DrowsinessSIDER
197Drug diversionOFFSIDES
198Drug level changedOFFSIDES
199Dry skinSIDER
200Duodenal UlcerOFFSIDES
201Duodenal ulcer perforationOFFSIDES
202Dyslipidemias1981077
7705011
CTD
203DyspepsiaSIDER
204DysphasiaOFFSIDES
205DysphoniaOFFSIDES
206Ear dischargeOFFSIDES
207EczemaOFFSIDES
SIDER
208Electrocardiogram QRS complexOFFSIDES
209Electrocardiogram abnormalSIDER
210Emotional distressOFFSIDES
211Enlargement abdomenSIDER
212EpididymitisSIDER
213EpilepsySIDER
214EpistaxisSIDER
215Erosive gastritisOFFSIDES
216Essential HypertensionSIDER
217Expired drug administeredOFFSIDES
218Eye painSIDER
219Feeding tube complicationOFFSIDES
220Flat affectSIDER
221FlatulenceSIDER
222FlushingSIDER
223Free thyroxine index increasedOFFSIDES
224Gastric ulcerSIDER
225GastroenteritisOFFSIDES
SIDER
226Gastrointestinal arteriovenous malformationOFFSIDES
227Gastrointestinal mucosal disorderOFFSIDES
228Gaze palsyOFFSIDES
229Genital erosionOFFSIDES
230GingivitisSIDER
231GranulocytosisOFFSIDES
232Heart failure

View details

CTD
233HepatitisSIDER
234Hepatosplenic T-cell lymphomaOFFSIDES
235HepatosplenomegalyOFFSIDES
236HerniaSIDER
237HiccoughOFFSIDES
238Hypercholesterolemia12572707CTD
239HyperpigmentationOFFSIDES
240Hypertension worsenedSIDER
241Hypertensive cardiomyopathyOFFSIDES
242Hypertensive heart diseaseOFFSIDES
243Hypoaesthesia facialOFFSIDES
244HypokinesiaOFFSIDES
SIDER
245Hypotension, Orthostatic11725558CTD
246Immunosuppressant drug levelOFFSIDES
247ImpetigoOFFSIDES
248Influenza-like symptomsSIDER
249Infusion site mobility decreasedOFFSIDES
250Injection site cellulitisOFFSIDES
251Injury asphyxiationOFFSIDES
252Insulin Resistance12572707CTD
253Intermittent ClaudicationSIDER
254Intraoperative floppy iris syndromeSIDER
255Joint Range of Motion DecreasedOFFSIDES
256Joint sprainOFFSIDES
257Lacrimation abnormal NOSSIDER
258Left Ventricular HypertrophyOFFSIDES
259LeukopeniaSIDER
260Long QT SyndromeOFFSIDES
261LymphadenopathySIDER
262Lymphocyte stimulation test positiveOFFSIDES
263MalnutritionSIDER
264Metabolic acidosisOFFSIDES
265MetatarsalgiaOFFSIDES
266Mitral valve sclerosisOFFSIDES
267MononeuritisOFFSIDES
268Mood swingsSIDER
269Mucosal erosionOFFSIDES
270Musculoskeletal discomfortSIDER
271Myoglobin urine presentOFFSIDES
272MyopiaSIDER
273Nasal discomfortOFFSIDES
274Nephrogenic Fibrosing DermopathyOFFSIDES
275NephrolithiasisSIDER
276NervousnessSIDER
277NeutropeniaSIDER
278NocturiaSIDER
279OliguriaSIDER
280Oroantral FistulaOFFSIDES
281OsteomyelitisOFFSIDES
282OsteoradionecrosisOFFSIDES
283OsteosclerosisOFFSIDES
284Otitis MediaSIDER
285OverdoseOFFSIDES
286PallorSIDER
287ParesisSIDER
288Performance status decreasedOFFSIDES
289Perineal painSIDER
290Perinephric collectionOFFSIDES
291Peritoneal DialysisOFFSIDES
292PeritonitisOFFSIDES
293PharyngitisSIDER
294PhotophobiaSIDER
295Polymyalgia RheumaticaSIDER
296PolymyositisOFFSIDES
297PolyuriaSIDER
298Prescribed overdoseOFFSIDES
299PriapismSIDER
300Procedural hypotensionOFFSIDES
301Prostatic Hyperplasia

View details

CTD
302Prostatic Neoplasms10969806CTD
303Prostatism10364649CTD
304Psoriasis flare-upSIDER
305PsoriasisSIDER
306Pulmonary HypertensionOFFSIDES
307Pulmonary congestionOFFSIDES
308PurpuraSIDER
309Rash erythematousSIDER
310Rebound hypertensionOFFSIDES
311Rectal tenesmusSIDER
312Renal painSIDER
313Renal tubular acidosisOFFSIDES
314Renal tubular disorderOFFSIDES
315Respiratory FailureOFFSIDES
316Reticulocyte count decreasedOFFSIDES
317Retrograde ejaculationSIDER
318RhinitisOFFSIDES
SIDER
319RhinorrheaOFFSIDES
320ScotomaSIDER
321Semen abnormalSIDER
322Semen analysis abnormalSIDER
323SepsisSIDER
324Sexual DysfunctionSIDER
325ShockSIDER
326Sick Sinus SyndromeOFFSIDES
327Sigmoidoscopy abnormalOFFSIDES
328SinusitisOFFSIDES
SIDER
329Skin hypertrophyOFFSIDES
SIDER
330Skin lesionOFFSIDES
331Skin necrosisOFFSIDES
332Skin tightnessOFFSIDES
333SplenectomyOFFSIDES
334StarvationOFFSIDES
335StressOFFSIDES
336Sudden deathSIDER
337SweatingSIDER
338TensionSIDER
339ThirstSIDER
340TinnitusSIDER
341Tooth ErosionOFFSIDES
342Upper respiratory tract inflammationOFFSIDES
343Urination Disorders7539853
7539854
CTD
344Urine output increasedSIDER
345Urologic Diseases20126606CTD
346Vascular purpuraSIDER
347Vascular resistance systemic decreasedOFFSIDES
348Venous thrombosis limbOFFSIDES
349Ventricular Dysfunction, Left15105169CTD
350Vertebrobasilar InsufficiencyOFFSIDES
351VertigoSIDER
352Visual ImpairmentSIDER
353XerosisOFFSIDES
354jaundiceSIDER
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