MetaADEDB 2.0 @ LMMD
Nateglinide
(OELFLUMRDSZNSF-OFLPRAFFSA-N)
Structure
SMILES
CC(C1CCC(CC1)C(=O)N[C@@H](C(=O)O)Cc1ccccc1)C
Type(s)
Approved; Investigational
ATC code(s)
A10BX03
Molecular Formula:
C19H27NO3
Molecular Weight:
317.423
Log P:
3.6518
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
66.4
CAS Number(s):
105746-37-0; 105816-04-4; 105816-06-6
Synonym(s)
1.
Nateglinide
2.
A 4166
3.
A-4166
4.
AY 4166
5.
AY-4166
6.
DJN 608
7.
Fastic
8.
N-((4-Isopropylcyclohexyl)carbonyl)phenylalanine
9.
Nate-Glinide
10.
Nateglinide, (D-Phe)-isomer
11.
Nateglinide, (cis,D-Phe)-isomer
12.
Senaglinide
13.
Starlix
14.
Starsis
15.
A4166
16.
AY4166
External Link(s)
MeSHD000077715
PubChem Compound5311309
BindingDB50344967
ChEBI31897
94617
CHEMBLCHEMBL783
CHEMBL2114389
DrugBankDB00731
DrugCentral1886
IUPHAR/BPS Guide to PHARMACOLOGY6833
KEGGcpd:C12508
dr:D01111
Therapeutic Target DatabaseD06PSS
ZINC9689
100015346
101489663
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 14
Canada Vigilance: 1		Canada Vigilance
US FAERS
2Blood glucose increasedFAERS: 10US FAERS
3DizzinessFAERS: 9OFFSIDES
SIDER
US FAERS
4Product quality issueFAERS: 7US FAERS
5Alanine Aminotransferase IncreasedFAERS: 6OFFSIDES
US FAERS
6Aspartate Aminotransferase IncreasedFAERS: 6US FAERS
7NauseaFAERS: 6OFFSIDES
SIDER
US FAERS
8Blood glucose decreasedFAERS: 5OFFSIDES
US FAERS
9Myocardial InfarctionFAERS: 5US FAERS
10Cerebrovascular accidentFAERS: 4US FAERS
11CholelithiasisFAERS: 4US FAERS
12Diabetes mellitus inadequate controlFAERS: 4OFFSIDES
US FAERS
13Gamma-Glutamyltransferase IncreasedFAERS: 4OFFSIDES
US FAERS
14HepatitisFAERS: 4OFFSIDES
US FAERS
15HypersensitivityFAERS: 4SIDER
US FAERS
16PneumoniaFAERS: 4US FAERS
17Product taste abnormalFAERS: 4US FAERS
18Respiratory arrestFAERS: 4US FAERS
19Urinary tract infectionFAERS: 4US FAERS
20UrticariaFAERS: 4SIDER
US FAERS
21ArthralgiaFAERS: 3US FAERS
22AstheniaFAERS: 3OFFSIDES
SIDER
US FAERS
23Blood glucose abnormalFAERS: 3OFFSIDES
US FAERS
24Blood glucose fluctuationFAERS: 3OFFSIDES
US FAERS
25Brain DeathFAERS: 3US FAERS
26Cardiac ArrestFAERS: 3US FAERS
27DysgeusiaFAERS: 3OFFSIDES
US FAERS
28MyalgiaFAERS: 3US FAERS
29Product substitution issueFAERS: 3US FAERS
30PruritusFAERS: 3SIDER
US FAERS
31SepsisFAERS: 3US FAERS
32VomitingFAERS: 3SIDER
US FAERS
33Weight decreasedFAERS: 3US FAERS
34Abdominal PainFAERS: 2OFFSIDES
SIDER
US FAERS
35Altered state of consciousnessFAERS: 2US FAERS
36ArthritisFAERS: 2US FAERS
37Blood albumin decreasedFAERS: 2US FAERS
38Blood alkaline phosphatase increasedFAERS: 2OFFSIDES
US FAERS
39Blood lactate dehydrogenase increasedFAERS: 2OFFSIDES
US FAERS
40Blood potassium increasedFAERS: 2OFFSIDES
US FAERS
41CardiomegalyFAERS: 2US FAERS
42CataractFAERS: 2US FAERS
43Chest PainFAERS: 2OFFSIDES
US FAERS
44Electrocardiogram abnormalFAERS: 2US FAERS
45FatigueFAERS: 2OFFSIDES
SIDER
US FAERS
46Gastric LavageFAERS: 2US FAERS
47GastritisFAERS: 2US FAERS
48IleusFAERS: 2US FAERS
49Impaired insulin secretionFAERS: 2OFFSIDES
US FAERS
50MyositisFAERS: 2US FAERS
51NephrolithiasisFAERS: 2US FAERS
52PancytopeniaFAERS: 2US FAERS
53Pulmonary congestionFAERS: 2OFFSIDES
US FAERS
54Suicide attemptFAERS: 2US FAERS
55SyncopeFAERS: 2US FAERS
56Transaminases increasedFAERS: 2US FAERS
57jaundiceFAERS: 2SIDER
US FAERS
58nervous system disorderFAERS: 2US FAERS
59Accidental exposureFAERS: 1US FAERS
60Acute myocardial infarctionFAERS: 1OFFSIDES
US FAERS
61AngioplastyFAERS: 1US FAERS
62AnxietyFAERS: 1US FAERS
63AsthmaFAERS: 1US FAERS
64Atrial FibrillationFAERS: 1US FAERS
65Back PainFAERS: 1SIDER
US FAERS
66Blood amylase increasedFAERS: 1US FAERS
67Blood cholesterol abnormalFAERS: 1OFFSIDES
US FAERS
68Blood creatinine increasedFAERS: 1OFFSIDES
US FAERS
69Brain natriuretic peptide increasedFAERS: 1US FAERS
70BronchitisFAERS: 1OFFSIDES
SIDER
US FAERS
71Calcium deficiencyFAERS: 1US FAERS
72Chest discomfortFAERS: 1US FAERS
73CholangitisFAERS: 1US FAERS
74CystitisFAERS: 1US FAERS
75Depressed Level of ConsciousnessFAERS: 1OFFSIDES
US FAERS
76Diabetes MellitusFAERS: 118499878CTD
US FAERS
77Drug exposure during pregnancyFAERS: 1US FAERS
78Drug prescribing errorFAERS: 1US FAERS
79Drug toxicityFAERS: 1OFFSIDES
US FAERS
80DyspepsiaFAERS: 1OFFSIDES
SIDER
US FAERS
81Emotional distressFAERS: 1US FAERS
82EpilepsyFAERS: 1US FAERS
83EructationFAERS: 1US FAERS
84ErythemaFAERS: 1US FAERS
85Feeling abnormalFAERS: 1OFFSIDES
US FAERS
86FlatulenceFAERS: 1OFFSIDES
US FAERS
87FractureFAERS: 1US FAERS
88Gastric BypassFAERS: 1US FAERS
89GastroenteritisFAERS: 1OFFSIDES
US FAERS
90GingivitisFAERS: 1US FAERS
91HeadacheFAERS: 1US FAERS
92HypotensionFAERS: 1US FAERS
93Increased upper airway secretionFAERS: 1US FAERS
94InfectionFAERS: 1US FAERS
95InflammationFAERS: 1US FAERS
96Intentional misuseFAERS: 1US FAERS
97Intestinal ObstructionFAERS: 1US FAERS
98MYELODYSPLASTIC SYNDROMEFAERS: 1US FAERS
99MalaiseFAERS: 1US FAERS
100Memory impairmentFAERS: 1US FAERS
101Mental status changesFAERS: 1OFFSIDES
US FAERS
102MonoplegiaFAERS: 1US FAERS
103NervousnessFAERS: 1US FAERS
104No adverse eventFAERS: 1US FAERS
105NocturiaFAERS: 1US FAERS
106ObstructionFAERS: 1US FAERS
107Pancreatic carcinomaFAERS: 1US FAERS
108PancreatitisFAERS: 1OFFSIDES
US FAERS
109PemphigusFAERS: 1US FAERS
110Pityriasis RoseaFAERS: 1US FAERS
111Product comminglingFAERS: 1US FAERS
112Product size issueFAERS: 1US FAERS
113Product use complaintFAERS: 1US FAERS
114Psychiatric symptomFAERS: 1US FAERS
115Respiratory FailureFAERS: 1US FAERS
116SinusitisFAERS: 1US FAERS
117SomnolenceFAERS: 1US FAERS
118Sudden deathFAERS: 1OFFSIDES
US FAERS
119SwellingFAERS: 1US FAERS
120Thermal burnFAERS: 1US FAERS
121ThrombocytopeniaFAERS: 1US FAERS
122ThrombosisFAERS: 1US FAERS
123Unevaluable eventFAERS: 1US FAERS
124Unresponsive to stimuliFAERS: 1US FAERS
125Ureteric fistulaFAERS: 1US FAERS
126Urinary RetentionFAERS: 1US FAERS
127Visual ImpairmentFAERS: 1US FAERS
128Visual disturbanceFAERS: 1OFFSIDES
US FAERS
129Wound dehiscenceFAERS: 1US FAERS
130Wrong technique in drug usage processFAERS: 1US FAERS
131Wrong technique in product usage processFAERS: 1US FAERS
132Abdominal discomfortOFFSIDES
133AcarodermatitisOFFSIDES
134Accidental needle stickOFFSIDES
135Acid refluxOFFSIDES
136AcidosisOFFSIDES
137AcneOFFSIDES
138Acute Coronary SyndromeOFFSIDES
139Acute prerenal failureOFFSIDES
140Acute respiratory failureOFFSIDES
141Acute sinusitisOFFSIDES
142AdenomaOFFSIDES
143Adrenal massOFFSIDES
144Adverse eventOFFSIDES
145Alcohol consumptionOFFSIDES
146Alopecia totalisOFFSIDES
147AlveolitisOFFSIDES
148Androgenetic AlopeciaOFFSIDES
149AngiodysplasiaOFFSIDES
150AnhedoniaOFFSIDES
151AnorexiaOFFSIDES
152Anoxic EncephalopathyOFFSIDES
153Anti-insulin antibody positiveOFFSIDES
154Aortic AneurysmOFFSIDES
155ApathyOFFSIDES
156ArteriosclerosisOFFSIDES
157ArthropathySIDER
158AscitesOFFSIDES
159AtaxiaOFFSIDES
160AtelectasisOFFSIDES
161Autoantibody positiveOFFSIDES
162Autoimmune thyroiditisOFFSIDES
163Band neutrophil percentage decreasedOFFSIDES
164Basal cell carcinomaOFFSIDES
165Basophil count abnormalOFFSIDES
166Bile duct stent insertionOFFSIDES
167Biliary dilatationOFFSIDES
168BilomaOFFSIDES
169Bipolar DisorderOFFSIDES
170Bladder NeoplasmOFFSIDES
171BlepharospasmOFFSIDES
172Blood 25-hydroxycholecalciferol decreasedOFFSIDES
173Blood GlucoseOFFSIDES
174Blood antidiuretic hormone increasedOFFSIDES
175Blood beta-D-glucan increasedOFFSIDES
176Blood chloride decreasedOFFSIDES
177Blood chloride increasedOFFSIDES
178Blood creatine abnormalOFFSIDES
179Blood creatine phosphokinase MB increasedOFFSIDES
180Blood creatine phosphokinase increasedOFFSIDES
181Blood insulin abnormalOFFSIDES
182Blood iron decreasedOFFSIDES
183Blood magnesium decreasedOFFSIDES
184Blood osmolarity decreasedOFFSIDES
185Blood parathyroid hormone increasedOFFSIDES
186Blood phosphorus decreasedOFFSIDES
187Blood pressure orthostatic increasedOFFSIDES
188Blood urine presentOFFSIDES
189Bone lesionOFFSIDES
190Bronchial irritationOFFSIDES
191BronchiectasisOFFSIDES
192BronchopneumoniaOFFSIDES
193Carcinoembryonic antigen increasedOFFSIDES
194Cardiac ablationOFFSIDES
195Catheter placementOFFSIDES
196Cerebellar infarctionOFFSIDES
197Choking sensationOFFSIDES
198Chronic Obstructive Airway DiseaseOFFSIDES
199Chronic left ventricular failureOFFSIDES
200Circumstance or information capable of leading to medication errorOFFSIDES
201CirrhosisOFFSIDES
202Clostridium colitisOFFSIDES
203Cold sweatOFFSIDES
204ColectomyOFFSIDES
205Completed SuicideOFFSIDES
206Concomitant disease progressionOFFSIDES
207Congenital hypertrichosisOFFSIDES
208Congenital tricuspid valve incompetenceOFFSIDES
209Culture positiveOFFSIDES
210DehydrationOFFSIDES
211DemyelinationOFFSIDES
212DermatitisSIDER
213DermatomyositisOFFSIDES
214Device FailureOFFSIDES
215DiabetesOFFSIDES
216DiarrheaOFFSIDES
217Diastolic dysfunctionOFFSIDES
218Diffuse Large B-Cell LymphomaOFFSIDES
219Disease ProgressionOFFSIDES
220DiverticulitisOFFSIDES
221DiverticulosisOFFSIDES
222Drug withdrawal headacheOFFSIDES
223Duodenal ObstructionOFFSIDES
224Duodenal perforationOFFSIDES
225DuodenitisOFFSIDES
226DyslaliaOFFSIDES
227Dysthymic DisorderOFFSIDES
228Early satietyOFFSIDES
229Economic problemOFFSIDES
230Electrocardiogram ST segment abnormalOFFSIDES
231EmpyemaOFFSIDES
232Endodontic procedureOFFSIDES
233Endometrial HyperplasiaOFFSIDES
234Enterobacter pneumoniaOFFSIDES
235Enterococcal infectionOFFSIDES
236EnuresisOFFSIDES
237EpididymitisOFFSIDES
238EpistaxisOFFSIDES
239Erosive gastritisOFFSIDES
240Erythema MultiformeSIDER
241Escherichia urinary tract infectionOFFSIDES
242Essential HypertensionOFFSIDES
243Extremity contractureOFFSIDES
244Fatty LiverOFFSIDES
245Femoral artery occlusionOFFSIDES
246Flu symptomsSIDER
247Fluid overloadOFFSIDES
248FolliculitisOFFSIDES
249Food cravingOFFSIDES
250GangreneOFFSIDES
251Gastric ulcerOFFSIDES
252Gastrointestinal PainSIDER
253Gastrointestinal hypermotilityOFFSIDES
254Gastrointestinal ulcerOFFSIDES
255Gastrooesophageal cancerOFFSIDES
256Genital erosionOFFSIDES
257GlobulinuriaOFFSIDES
258GoiterOFFSIDES
259GoutOFFSIDES
260Graft infectionOFFSIDES
261Guttate psoriasisOFFSIDES
262HiccoughOFFSIDES
263Hilar lymphadenopathyOFFSIDES
264Hyperinsulinism11074662CTD
265Hyperosmolar stateOFFSIDES
266Hypertensive heart diseaseOFFSIDES
267HyperventilationOFFSIDES
268Hypocoagulable stateOFFSIDES
269Hypoglycemia11074662CTD
270Iatrogenic injuryOFFSIDES
271ImmobileOFFSIDES
272Impaired gastric emptyingOFFSIDES
273Implantable defibrillator insertionOFFSIDES
274IncontinenceOFFSIDES
275Incorrect dose administeredOFFSIDES
276IndurationOFFSIDES
277InfluenzaSIDER
278Infrequent bowel movementsOFFSIDES
279Injection site coldnessOFFSIDES
280Injection site dermatitisOFFSIDES
281Injection site discomfortOFFSIDES
282Injection site erythemaOFFSIDES
283Injection site irritationOFFSIDES
284Injection site noduleOFFSIDES
285Injection site pruritusOFFSIDES
286Injection site ulcerOFFSIDES
287Injection site urticariaOFFSIDES
288Injection site vesiclesOFFSIDES
289Insulin C-peptide decreasedOFFSIDES
290Insulin-like growth factor decreasedOFFSIDES
291Insulin-requiring type 2 diabetes mellitusOFFSIDES
292Intention tremorOFFSIDES
293Intermittent ClaudicationOFFSIDES
294Intervertebral Disc DegenerationOFFSIDES
295Intestinal resectionOFFSIDES
296Intranasal fungal infectionOFFSIDES
297Intraocular pressure testOFFSIDES
298Joint Range of Motion DecreasedOFFSIDES
299Joint injuryOFFSIDES
300Joint sprainOFFSIDES
301Joint stiffnessOFFSIDES
302Joint warmthOFFSIDES
303Jugular vein distensionOFFSIDES
304Keratitis siccaOFFSIDES
305LaparotomyOFFSIDES
306Latent Autoimmune Diabetes in AdultsOFFSIDES
307Left Ventricular HypertrophyOFFSIDES
308LeukoencephalopathyOFFSIDES
309Life expectancy shortenedOFFSIDES
310Ligament injuryOFFSIDES
311Limb injuryOFFSIDES
312LithotripsyOFFSIDES
313Low Cardiac Output SyndromeOFFSIDES
314Lung AbscessOFFSIDES
315Lupus-like syndromeOFFSIDES
316LymphoceleOFFSIDES
317Lymphocyte count abnormalOFFSIDES
318Lymphocyte count decreasedOFFSIDES
319Lymphocyte percentage decreasedOFFSIDES
320Lymphocyte stimulation testOFFSIDES
321LymphomaOFFSIDES
322MalnutritionSIDER
323Mass excisionOFFSIDES
324MastectomyOFFSIDES
325Medication residueOFFSIDES
326Metabolic acidosisOFFSIDES
327Multiple allergiesOFFSIDES
328Muscle WeaknessOFFSIDES
329Musculoskeletal PainOFFSIDES
330Myoclonic EpilepsyOFFSIDES
331Myoglobin blood increasedOFFSIDES
332Myoglobin urine presentOFFSIDES
333MyosclerosisOFFSIDES
334NasopharyngitisOFFSIDES
335Nervous tensionOFFSIDES
336Neutrophil count abnormalOFFSIDES
337Nodule on extremityOFFSIDES
338NoduleOFFSIDES
339Non-cardiac chest painOFFSIDES
340Ocular icterusOFFSIDES
341Oculomucocutaneous syndromeOFFSIDES
342OsteoporosisOFFSIDES
343PainOFFSIDES
344PalpitationsSIDER
345Pancreatic PseudocystOFFSIDES
346Pancreatic duct dilatationOFFSIDES
347ParacentesisOFFSIDES
348Paranasal sinus hypersecretionOFFSIDES
349Pelvic venous thrombosisOFFSIDES
350Peptic Ulcer PerforationOFFSIDES
351Perianal abscessOFFSIDES
352PeriarthritisOFFSIDES
353Pericardial effusionOFFSIDES
354Pharmaceutical product complaintOFFSIDES
355Pharyngolaryngeal PainOFFSIDES
356Platelet aggregation inhibitionOFFSIDES
357Pleural decorticationOFFSIDES
358PleurisyOFFSIDES
359Pneumocystis jiroveci pneumoniaOFFSIDES
360Polymyalgia RheumaticaOFFSIDES
361PolyuriaSIDER
362Poor peripheral circulationOFFSIDES
363Postural Orthostatic Tachycardia SyndromeOFFSIDES
364Prescribed overdoseOFFSIDES
365Primary sequestrumOFFSIDES
366Productive CoughOFFSIDES
367PseudarthrosisOFFSIDES
368Pulmonary necrosisOFFSIDES
369PurulenceOFFSIDES
370PyelonephritisOFFSIDES
371Pyloric StenosisOFFSIDES
372PyuriaOFFSIDES
373QuadriparesisOFFSIDES
374Quality of life decreasedOFFSIDES
375Radiation PneumonitisOFFSIDES
376RalesOFFSIDES
377Reflux gastritisOFFSIDES
378Renal Artery StenosisOFFSIDES
379Retinal exudatesOFFSIDES
380RhinorrheaOFFSIDES
381RhonchiOFFSIDES
382Sick Sinus SyndromeOFFSIDES
383Sinus headacheOFFSIDES
384Skin hypertrophyOFFSIDES
385Skin lesionOFFSIDES
386Skin tightnessOFFSIDES
387Small intestine carcinomaOFFSIDES
388Spinal column stenosisOFFSIDES
389Spirometry abnormalOFFSIDES
390SplenectomyOFFSIDES
391SpondylolisthesisOFFSIDES
392Sputum culture positiveOFFSIDES
393StressOFFSIDES
394Sudden Cardiac DeathOFFSIDES
395SweatingSIDER
396Synovial CystOFFSIDES
397TachyphylaxisOFFSIDES
398Therapeutic response unexpectedOFFSIDES
399ThirstSIDER
400Thoracic vertebral fractureOFFSIDES
401Thrombotic strokeOFFSIDES
402TinnitusOFFSIDES
403Tongue bitingOFFSIDES
404TraumaSIDER
405TremblingSIDER
406TremorSIDER
407UlcerOFFSIDES
408Umbilical herniaOFFSIDES
409Upper respiratory tract inflammationOFFSIDES
410Urine osmolarity increasedOFFSIDES
411Urine output increasedSIDER
412Uterine PolypOFFSIDES
413Venous stenosisOFFSIDES
414Vertebrobasilar InsufficiencyOFFSIDES
415Vitamin B 12 DeficiencyOFFSIDES
416Vulvovaginal drynessOFFSIDES
417Weight GainOFFSIDES
418White blood cell count abnormalOFFSIDES
419angiogramOFFSIDES
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120237

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.