MetaADEDB 2.0 @ LMMD
Flunitrazepam
(PPTYJKAXVCCBDU-UHFFFAOYSA-N)
Structure
SMILES
CN1C(=O)CN=C(c2c1ccc(c2)[N+](=O)[O-])c1ccccc1F
Type(s)
Approved; Illicit
ATC code(s)
N05CD03
Molecular Formula:
C16H12FN3O3
Molecular Weight:
313.283
Log P:
2.5715
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
0
TPSA:
78.49
CAS Number(s):
1622-62-4
Synonym(s)
1.
Flunitrazepam
2.
Fluridrazepam
3.
Rohypnol
4.
Fluni 1A Pharma
5.
Flunibeta
6.
Flunimerck
7.
Fluninoc
8.
Flunitrazepam-Neuraxpharm
9.
Flunitrazepam-Ratiopharm
10.
Flunitrazepam-Teva
11.
Flunizep Von Ct
12.
Narcozep
13.
RO-5-4200
14.
Rohipnol
15.
Flunitrazepam Neuraxpharm
16.
Flunitrazepam Ratiopharm
17.
Flunitrazepam Teva
18.
RO54200
19.
Von Ct, Flunizep
External Link(s)
MeSHD005445
PubChem Compound3380
BindingDB25878
ChEBI31622
CHEMBLCHEMBL13280
DrugBankDB01544
DrugCentral1202
IUPHAR/BPS Guide to PHARMACOLOGY4193
4360
KEGGdr:D01230
Therapeutic Target DatabaseD0W2NM
ZINC3812994
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal Compartment SyndromeOFFSIDES
2Abdominal PainOFFSIDES
3Abdominal symptomOFFSIDES
4AbuliaOFFSIDES
5AbuseOFFSIDES
6Activation syndromeOFFSIDES
7Acute respiratory failureOFFSIDES
8AgitationSIDER
9Alanine Aminotransferase IncreasedOFFSIDES
10Alcohol poisoningOFFSIDES
11Alcoholic IntoxicationOFFSIDES
12Altered state of consciousnessOFFSIDES
13AlveolitisOFFSIDES
14AmenorrheaOFFSIDES
15Amnesia, Anterograde12108561
14550609
16087387		CTD
16AmnesiaCanada Vigilance: 27093
34412
6108778		CTD
SIDER
Canada Vigilance
17Analgesic drug level increasedOFFSIDES
18AngioedemaSIDER
19AnhidrosisOFFSIDES
20AnorexiaOFFSIDES
21AnosmiaOFFSIDES
22Anticholinergic SyndromeOFFSIDES
23Antidepressant drug clearance decreasedOFFSIDES
24AnuriaOFFSIDES
25AnxietyOFFSIDES
SIDER
26ApathyOFFSIDES
27Aphthous StomatitisOFFSIDES
28ApneaOFFSIDES
29Arterial Occlusive Diseases19003750CTD
30AscitesOFFSIDES
31AsphyxiaOFFSIDES
32Aspiration PneumoniaOFFSIDES
33AstheniaSIDER
34AtaxiaSIDER
35AuraOFFSIDES
36AutomatismOFFSIDES
37Beta 2 microglobulin increasedOFFSIDES
38BilomaOFFSIDES
39Bipolar DisorderOFFSIDES
40Bipolar I disorderOFFSIDES
41BlepharoptosisOFFSIDES
42Blood albumin decreasedOFFSIDES
43Blood alkaline phosphatase increasedOFFSIDES
44Blood beta-D-glucan increasedOFFSIDES
45Blood chloride abnormalOFFSIDES
46Blood chloride decreasedOFFSIDES
47Blood chloride increasedOFFSIDES
48Blood cholinesterase decreasedOFFSIDES
49Blood cortisol increasedOFFSIDES
50Blood creatine increasedOFFSIDES
51Blood creatine phosphokinase MB increasedOFFSIDES
52Blood creatine phosphokinase increasedOFFSIDES
53Blood glucose abnormalOFFSIDES
54Blood glucose fluctuationOFFSIDES
55Blood lactate dehydrogenaseOFFSIDES
56Blood lactate dehydrogenase increasedOFFSIDES
57Blood magnesium increasedOFFSIDES
58Blood parathyroid hormone increasedOFFSIDES
59Blood phosphorus decreasedOFFSIDES
60Blood potassium decreasedOFFSIDES
61Blood potassium increasedOFFSIDES
62Blood potassiumOFFSIDES
63Blood pressure immeasurableOFFSIDES
64Blood prolactin increasedOFFSIDES
65Blood sodium increasedOFFSIDES
66Blood sodiumOFFSIDES
67Blood triglycerides decreasedOFFSIDES
68Blunted affectOFFSIDES
69Body TemperatureOFFSIDES
70Bronchoalveolar LavageOFFSIDES
71BruxismOFFSIDES
72Bulbar palsyOFFSIDES
73C-reactive protein abnormalOFFSIDES
74Cardiac DeathOFFSIDES
75Cardiac HypertrophyOFFSIDES
76Cardiac function test abnormalOFFSIDES
77Cardiac perforationOFFSIDES
78CardiotoxicityOFFSIDES
79Cardiovascular insufficiencyOFFSIDES
80CataplexyOFFSIDES
81CatatoniaOFFSIDES
82Central nervous system lesionOFFSIDES
83Cerebellar infarctionOFFSIDES
84Cerebral artery occlusionOFFSIDES
85Chemotherapeutic drug level increasedOFFSIDES
86ChokingOFFSIDES
87Chronic Fatigue SyndromeOFFSIDES
88Citrobacter infectionOFFSIDES
89Cogwheel RigidityOFFSIDES
90Completed SuicideOFFSIDES
91Confusion7095
6109383
6116298		CTD
92Conjunctival depositOFFSIDES
93Consciousness fluctuatingOFFSIDES
94Contracted bladderOFFSIDES
95Corneal erosionOFFSIDES
96CryingOFFSIDES
97Deafness NeurosensoryOFFSIDES
98Depressed Level of ConsciousnessOFFSIDES
99Depressed moodOFFSIDES
100Depressive disorder8238650CTD
101DermatitisSIDER
102Diabetes InsipidusOFFSIDES
103DiaphragmalgiaOFFSIDES
104Diet refusalOFFSIDES
105Diplopia3160028CTD
SIDER
106DiscomfortSIDER
107Disorders of Excessive Somnolence3160028CTD
108DisorientationSIDER
109Disseminated Intravascular CoagulationOFFSIDES
110Disuse syndromeOFFSIDES
111Dizziness6103707CTD
SIDER
112DrowsinessOFFSIDES
SIDER
113Drug abuserOFFSIDES
114Drug administered at inappropriate siteOFFSIDES
115Drug diversionOFFSIDES
116Drug exposure via breast milkOFFSIDES
117Drug toxicityOFFSIDES
118DysarthriaSIDER
119DysgraphiaOFFSIDES
120DyslaliaOFFSIDES
121Dyspnea10653217
15298663		CTD
122Dyspnoea exacerbatedOFFSIDES
123Dysthymic DisorderOFFSIDES
124DysuriaOFFSIDES
125Echocardiogram abnormalOFFSIDES
126Elevated moodOFFSIDES
127Emotional distressSIDER
128EmpyemaOFFSIDES
129EncephalitisOFFSIDES
130Enterococcal infectionOFFSIDES
131Enterocolitis bacterialOFFSIDES
132EnterocolitisOFFSIDES
133Eosinophil percentage decreasedOFFSIDES
134Erectile dysfunctionOFFSIDES
135Erythema MultiformeOFFSIDES
136ErythropeniaOFFSIDES
137Esophageal StenosisOFFSIDES
138Euphoric moodOFFSIDES
139Eyelid Function DisorderOFFSIDES
140Eyelids pruritusOFFSIDES
141FatigueSIDER
142Feeding disorder neonatalOFFSIDES
143Feeling abnormalSIDER
144Food AllergyOFFSIDES
145GalactorrheaOFFSIDES
146Gamma-Glutamyltransferase IncreasedOFFSIDES
147GastroduodenitisOFFSIDES
148Gastrointestinal hypomotilityOFFSIDES
149GlossoptosisOFFSIDES
150Graft infectionOFFSIDES
151Granulocyte count decreasedOFFSIDES
152Grip strengthOFFSIDES
153Head titubationOFFSIDES
154HeadacheSIDER
155HiccoughOFFSIDES
156High density lipoprotein increasedOFFSIDES
157HordeolumOFFSIDES
158HostilityOFFSIDES
159HyperventilationOFFSIDES
160HypomaniaOFFSIDES
161HypophagiaOFFSIDES
162HyporeflexiaOFFSIDES
163HypotensionSIDER
164Hypoxia15298663CTD
165Ileal ulcerOFFSIDES
166IncoherentOFFSIDES
167IncontinenceOFFSIDES
168Infected epidermal cystOFFSIDES
169Infection in an immunocompromised hostOFFSIDES
170Injection site noduleOFFSIDES
171Injury asphyxiationOFFSIDES
172Intention tremorOFFSIDES
173Intentional drug misuseOFFSIDES
174Intentional misuseOFFSIDES
175Intentional self-injuryOFFSIDES
176Intestinal hypomotilityOFFSIDES
177IntubationOFFSIDES
178Ischemia19003750CTD
179Japan coma scale abnormalOFFSIDES
180Kidney Diseases6527399CTD
181Laboratory test interferenceOFFSIDES
182LeukoencephalopathyOFFSIDES
183Leukopenia neonatalOFFSIDES
184Locked-In SyndromeOFFSIDES
185Lymphocyte percentage decreasedOFFSIDES
186Lymphocyte stimulation test positiveOFFSIDES
187MacrocytosisOFFSIDES
188MalaiseSIDER
189Malignant neoplasm progressionOFFSIDES
190Mallory-Weiss SyndromeOFFSIDES
191MegacolonOFFSIDES
192Metabolic acidosisOFFSIDES
193Metamyelocyte count increasedOFFSIDES
194MonoplegiaOFFSIDES
195MorpheaOFFSIDES
196Motor Skills Disorders7093CTD
197Mouth BreathingOFFSIDES
198Multiple drug overdoseOFFSIDES
199Multiple drug overdose intentionalOFFSIDES
200Multiple sclerosis relapseOFFSIDES
201MurderOFFSIDES
202Muscle necrosisOFFSIDES
203Muscle tightnessOFFSIDES
204Musculoskeletal stiffnessOFFSIDES
205Myelocyte count increasedOFFSIDES
206MyofascitisOFFSIDES
207Myoglobin blood increasedOFFSIDES
208Myoglobin urine presentOFFSIDES
209NasopharyngitisOFFSIDES
210Neuroleptic Malignant SyndromeOFFSIDES
211Nuchal RigidityOFFSIDES
212NystagmusOFFSIDES
213Oculomucocutaneous syndromeOFFSIDES
214Open woundOFFSIDES
215Oropharyngeal painOFFSIDES
216OrthopneaOFFSIDES
217OverdoseOFFSIDES
218Pain6103707CTD
219ParapsoriasisOFFSIDES
220Paroxysmal perceptual alterationOFFSIDES
221Partner stressOFFSIDES
222Patient restraintOFFSIDES
223PeriarthritisOFFSIDES
224Personality ChangeOFFSIDES
225PharyngotonsillitisOFFSIDES
226Phlebitis6108669CTD
227Physical assaultOFFSIDES
228PiloerectionOFFSIDES
229PleurisyOFFSIDES
230Pneumocystis jiroveci pneumoniaOFFSIDES
231PoriomaniaOFFSIDES
232Post procedural bile leakOFFSIDES
233Postoperative Complications717770CTD
234Protein total decreasedOFFSIDES
235Psychiatric symptomOFFSIDES
236Psychomotor Agitation7095CTD
237Psychomotor skills impairedOFFSIDES
238Psychotic Disorders14670884CTD
239Pulmonary InfarctionOFFSIDES
240Renin increasedOFFSIDES
241Respiratory FailureOFFSIDES
242Retinal VasculitisOFFSIDES
243RetrocollisOFFSIDES
244Rhabdomyolysis19003750CTD
OFFSIDES
245RhinitisOFFSIDES
246SchizophreniaOFFSIDES
247Seizures6130832
6498581		CTD
248Sexual abuseOFFSIDES
249Silent myocardial infarctionOFFSIDES
250Skin lacerationOFFSIDES
251Skin lesionOFFSIDES
252Sleep Initiation and Maintenance Disorders8302193CTD
253Sleep Wake Disorders430730
15298663		CTD
254Sleep-related eating disorderOFFSIDES
255Slurred speechSIDER
256SoliloquyOFFSIDES
257Somatoform DisorderOFFSIDES
258SomnolenceSIDER
259Sputum retentionOFFSIDES
260Status EpilepticusOFFSIDES
261Stevens-Johnson SyndromeOFFSIDES
262SubileusOFFSIDES
263Substance Withdrawal Syndrome

View details

430730
1327709
1946580
3241876
8773293
10690749
10706979
 		CTD
264Sudden deathOFFSIDES
265SweatingSIDER
266Tachycardia7095CTD
SIDER
267Tarsal Tunnel SyndromeOFFSIDES
268TheftOFFSIDES
269Thrombocytopenia6527399CTD
270Thrombophlebitis6107100CTD
271Thrombosis22381CTD
272TinnitusOFFSIDES
273Transmission of drug via semenOFFSIDES
274TremorSIDER
275Unevaluable eventOFFSIDES
276Unresponsive to verbal stimuliOFFSIDES
277Urine output increasedOFFSIDES
278Vascular stent insertionOFFSIDES
279Venous Thrombosis15298663CTD
280Venous thrombosis limbOFFSIDES
281Water IntoxicationOFFSIDES
282jejunitisOFFSIDES
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