MetaADEDB 2.0 @ LMMD
Dehydroepiandrosterone
(FMGSKLZLMKYGDP-USOAJAOKSA-N)
Structure
SMILES
O[C@H]1CC[C@]2(C(=CC[C@@H]3[C@@H]2CC[C@]2([C@H]3CCC2=O)C)C1)C
Type(s)
Approved; Investigational; Nutraceutical
ATC code(s)
A14AA07; G03EA03; G03XX01
Molecular Formula:
C19H28O2
Molecular Weight:
288.424
Log P:
3.8792
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
1
TPSA:
37.3
CAS Number(s):
53-43-0
Synonym(s)
1.
Dehydroepiandrosterone
2.
Dehydroisoandrosterone
3.
Prasterone
4.
5-Androsten-3-beta-hydroxy-17-one
5.
5-Androsten-3-ol-17-one
6.
Androstenolone
7.
DHEA
8.
Prasterone, 3 alpha-Isomer
9.
5 Androsten 3 beta hydroxy 17 one
10.
5 Androsten 3 ol 17 one
11.
Prasterone, 3 alpha Isomer
External Link(s)
MeSHD003687
PubChem Compound5881
BindingDB50223368
ChEBI28689
CHEMBLCHEMBL90593
DrugBankDB01708
DrugCentral795
IUPHAR/BPS Guide to PHARMACOLOGY2370
KEGGcpd:C01227
dr:D08409
Therapeutic Target DatabaseD0K0EK
D00OAW
ZINC3807917
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 32US FAERS
2Therapeutic response unexpectedFAERS: 27OFFSIDES
US FAERS
3Application site dischargeFAERS: 25US FAERS
4Vaginal DischargeFAERS: 25US FAERS
5Vulvovaginal burning sensationFAERS: 15US FAERS
6Burning sensationFAERS: 14US FAERS
7Vulvovaginal discomfortFAERS: 13US FAERS
8HeadacheFAERS: 10US FAERS
9PruritusFAERS: 10US FAERS
10Breast tendernessFAERS: 9US FAERS
11AlopeciaFAERS: 8US FAERS
12Drug ineffective for unapproved indicationFAERS: 7US FAERS
13Urinary tract infectionFAERS: 7US FAERS
14AgitationFAERS: 6US FAERS
15PainFAERS: 6US FAERS
16Product administration errorFAERS: 6US FAERS
17Application site painFAERS: 5US FAERS
18Product dose omissionFAERS: 5US FAERS
19Abdominal PainFAERS: 4OFFSIDES
US FAERS
20AnxietyFAERS: 4OFFSIDES
US FAERS
21Application site irritationFAERS: 4OFFSIDES
US FAERS
22FatigueFAERS: 4OFFSIDES
US FAERS
23Night sweatsFAERS: 4US FAERS
24Vulvovaginal pruritusFAERS: 4US FAERS
25AcneFAERS: 3US FAERS
26Back PainFAERS: 3US FAERS
27Dehydroepiandrosterone increasedFAERS: 3US FAERS
28DiscomfortFAERS: 3US FAERS
29Feeling abnormalFAERS: 3US FAERS
30HypersensitivityFAERS: 3US FAERS
31Mood swingsFAERS: 3US FAERS
32NauseaFAERS: 3OFFSIDES
US FAERS
33PalpitationsFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
34Pelvic PainFAERS: 3US FAERS
35Pelvic discomfortFAERS: 3US FAERS
36Vulvovaginal painFAERS: 3US FAERS
37Abdominal discomfortFAERS: 2OFFSIDES
US FAERS
38Administration site dischargeFAERS: 2US FAERS
39Atrophic vulvovaginitisFAERS: 2US FAERS
40Bladder painFAERS: 2US FAERS
41Blood testosterone increasedFAERS: 2US FAERS
42BronchitisFAERS: 2OFFSIDES
US FAERS
43ConstipationFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
44DysuriaFAERS: 2US FAERS
45Emotional disorderFAERS: 2US FAERS
46ErythemaFAERS: 2US FAERS
47Inappropriate schedule of product administrationFAERS: 2US FAERS
48MalaiseFAERS: 2US FAERS
49NasopharyngitisFAERS: 2US FAERS
50NervousnessFAERS: 2US FAERS
51Personality ChangeFAERS: 2US FAERS
52SwellingFAERS: 2US FAERS
53Urinary RetentionFAERS: 2US FAERS
54Uterine spasmFAERS: 2US FAERS
55Vulvovaginal erythemaFAERS: 2US FAERS
56Vulvovaginal mycotic infectionFAERS: 2US FAERS
57Vulvovaginal swellingFAERS: 2US FAERS
58Weight decreasedFAERS: 2US FAERS
59Adverse eventFAERS: 1OFFSIDES
US FAERS
60Alanine Aminotransferase IncreasedFAERS: 1US FAERS
61Anorectal discomfortFAERS: 1OFFSIDES
US FAERS
62Application site scarFAERS: 1US FAERS
63ArthralgiaFAERS: 1US FAERS
64ArthritisFAERS: 1US FAERS
65Aspartate Aminotransferase IncreasedFAERS: 1US FAERS
66AstheniaFAERS: 1OFFSIDES
US FAERS
67Benign anorectal neoplasmFAERS: 1US FAERS
68Bladder prolapseFAERS: 1US FAERS
69Blood alcohol increasedFAERS: 1US FAERS
70Blood alkaline phosphatase increasedFAERS: 1US FAERS
71Blood pressure inadequately controlledFAERS: 1US FAERS
72Chest PainFAERS: 1OFFSIDES
US FAERS
73ChromaturiaFAERS: 1US FAERS
74Circumstance or information capable of leading to medication errorFAERS: 1US FAERS
75CryingFAERS: 1OFFSIDES
US FAERS
76CystitisFAERS: 1US FAERS
77CystFAERS: 1US FAERS
78DizzinessFAERS: 1US FAERS
79Dry skinFAERS: 1US FAERS
80DysgeusiaFAERS: 1US FAERS
81Endometrial thickeningFAERS: 1US FAERS
82Exposure via partnerFAERS: 1US FAERS
83Flat affectFAERS: 1US FAERS
84FlushingFAERS: 1US FAERS
85FormicationFAERS: 1US FAERS
86Frustration tolerance decreasedFAERS: 1US FAERS
87GingivitisFAERS: 1US FAERS
88Incorrect route of product administrationFAERS: 1US FAERS
89InfectionFAERS: 1OFFSIDES
US FAERS
90InflammationFAERS: 1US FAERS
91Initial insomniaFAERS: 1US FAERS
92Intentional product misuseFAERS: 1US FAERS
93Irritable Bowel SyndromeFAERS: 1US FAERS
94Macular degenerationFAERS: 1US FAERS
95Memory impairmentFAERS: 1US FAERS
96Musculoskeletal chest painFAERS: 1US FAERS
97Oropharyngeal painFAERS: 1US FAERS
98Penile burning sensationFAERS: 1US FAERS
99Poor quality sleepFAERS: 1US FAERS
100Premenstrual crampsFAERS: 1US FAERS
101Premenstrual syndromeFAERS: 1US FAERS
102Product depositFAERS: 1US FAERS
103Protein urine presentFAERS: 1US FAERS
104ProteinuriaFAERS: 1US FAERS
105RestlessnessFAERS: 1US FAERS
106SinusitisFAERS: 1US FAERS
107SneezingFAERS: 1US FAERS
108StressFAERS: 1US FAERS
109Symptom recurrenceFAERS: 1US FAERS
110Therapeutic product effect decreasedFAERS: 1US FAERS
111Tooth InfectionFAERS: 1US FAERS
112ToothacheFAERS: 1US FAERS
113Urinary tract discomfortFAERS: 1US FAERS
114Uterine PolypFAERS: 1US FAERS
115VertigoFAERS: 1US FAERS
116Vulvovaginal drynessFAERS: 1US FAERS
117Vulvovaginal inflammationFAERS: 1US FAERS
118Vulvovaginal injuryFAERS: 1US FAERS
119Waist circumference increasedFAERS: 1US FAERS
120jaundiceFAERS: 1US FAERS
121Acid refluxOFFSIDES
122Adenocarcinoma9131265CTD
123AndropauseOFFSIDES
124AneurysmOFFSIDES
125Ankle FractureOFFSIDES
126Aphthous StomatitisOFFSIDES
127Application site burnOFFSIDES
128Application site pruritusOFFSIDES
129Application site rashOFFSIDES
130Application site swellingOFFSIDES
131Atrial tachycardiaOFFSIDES
132AutomatismOFFSIDES
133Bacterial conjunctivitisOFFSIDES
134Blood osmolarity increasedOFFSIDES
135Blood pressure fluctuationOFFSIDES
136Blood testosterone decreasedOFFSIDES
137Cardiac FlutterOFFSIDES
138Cardiac TamponadeOFFSIDES
139Cardiac perforationOFFSIDES
140Catalepsy24739405CTD
141Cervical dysplasiaOFFSIDES
142Choking sensationOFFSIDES
143Chronic ulcerative colitisOFFSIDES
144Clostridium difficile colitisOFFSIDES
145Cluster HeadacheOFFSIDES
146Cocaine-Related Disorders16309898
16421515
CTD
147Coronary angioplastyOFFSIDES
148Decreased immune responsivenessOFFSIDES
149DehydrationOFFSIDES
150DemyelinationOFFSIDES
151Depression suicidalOFFSIDES
152Device breakageOFFSIDES
153DiarrheaOFFSIDES
154Dihydrotestosterone decreasedOFFSIDES
155DiverticulitisOFFSIDES
156Drug withdrawal headacheOFFSIDES
157DysphoniaOFFSIDES
158Electromechanical dissociationOFFSIDES
159Enterococcal infectionOFFSIDES
160Erectile dysfunctionOFFSIDES
161Euphoric moodOFFSIDES
162Eyelid skin drynessCanada Vigilance: 1Canada Vigilance
163Eyelids pruritusCanada Vigilance: 1Canada Vigilance
164Feeding and Eating Disorders12659879CTD
165Feeling ColdOFFSIDES
166Female sexual arousal disorderOFFSIDES
167FibromyalgiaOFFSIDES
168GastroenteritisOFFSIDES
169Gastrointestinal inflammationOFFSIDES
170General physical health deteriorationOFFSIDES
171HerniaOFFSIDES
172HirsutismCanada Vigilance: 1Canada Vigilance
173HistoplasmosisOFFSIDES
174Hyperglycemia11228057CTD
175Injection site urticariaOFFSIDES
176Insulin Resistance27634381CTD
177Intention tremorOFFSIDES
178Joint sprainOFFSIDES
179Keratosis27634381CTD
180Left Ventricular HypertrophyOFFSIDES
181LethargyOFFSIDES
182Leukopenia neonatalOFFSIDES
183Liver Neoplasms, Experimental8603461CTD
184Liver neoplasms9175849
18709148
CTD
185Mammary Neoplasms, Experimental9131265
16457693
CTD
186Memory Disorders15451042CTD
187Mental impairmentOFFSIDES
188Multiple sclerosis relapseOFFSIDES
189Muscle WeaknessOFFSIDES
190Musculoskeletal discomfortOFFSIDES
191Nasal mucosal disorderOFFSIDES
192Nervous tensionOFFSIDES
193Non-cardiac chest painOFFSIDES
194Osteoporosis, Postmenopausal16397352CTD
195OsteoporosisOFFSIDES
196Pancreatic InsufficiencyOFFSIDES
197Panic Disorder15996752CTD
OFFSIDES
198Perivascular dermatitisOFFSIDES
199Polycystic Ovary Syndrome21062263
27634381
CTD
200Polycythemia15161484CTD
201Prenatal Exposure Delayed Effects15451042CTD
202Protein S decreasedOFFSIDES
203Pseudomonal sepsisOFFSIDES
204RhinalgiaOFFSIDES
205Schizophrenia24739405CTD
206Sjogren's SyndromeOFFSIDES
207Spontaneous penile erectionOFFSIDES
208Swelling of eyelidCanada Vigilance: 1Canada Vigilance
209Transaminases increasedOFFSIDES
210Urinary IncontinenceCanada Vigilance: 1Canada Vigilance
211Urinary tract infection pseudomonalOFFSIDES
212Vaginal mycosisOFFSIDES
213Weight Gain27634381CTD
OFFSIDES
214effusionOFFSIDES
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