MetaADEDB 2.0 @ LMMD
pirinixic acid
(SZRPDCCEHVWOJX-UHFFFAOYSA-N)
Structure
SMILES
OC(=O)CSc1nc(cc(n1)Cl)Nc1cccc(c1C)C
Molecular Formula:
C14H14ClN3O2S
Molecular Weight:
323.798
Log P:
3.7401
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
2
TPSA:
100.41
CAS Number(s):
50892-23-4
Synonym(s)
1.
pirinixic acid
2.
(4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio)acetic acid
3.
4-chloro-6-(2,3-dimethylphenyl)amino-2-pyrimidinylthioacetic acid
4.
4-chloro-6-(2,3-xylidinyl)-2-pyrimidinylthioacetic acid
5.
CXPTA
6.
WY 14,643
7.
WY-14,643
8.
WY14,643
9.
Wy 14643
10.
Wy-14643
11.
Wyeth 14,643
12.
Wyeth-14643
External Link(s)
MeSHC006253
PubChem Compound5694
BindingDB24566
ChEBI32509
CHEMBLCHEMBL295416
IUPHAR/BPS Guide to PHARMACOLOGY2666
KEGGcpd:C15617
Therapeutic Target DatabaseD09XCX
ZINC1963
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Acute Lung Injury18653653CTD
2Acute kidney injury12503032CTD
3Blood Coagulation Disorders19483382CTD
4Chemical and Drug Induced Liver Injury

View details

17483499
17962186
21262334
27853831
 		CTD
5Cholestasis19176532CTD
6Dermatitis, Atopic18249437CTD
7Dermatitis, Irritant11851881CTD
8Edema12083418CTD
9Fatty Liver12727805
19236843
20131406		CTD
10Feeding and Eating Disorders23153559CTD
11Heart Diseases21585347
23941634		CTD
12Heart failure20558911CTD
13Hepatomegaly

View details

7497472
16221962
17483499
17690133
18467677
19176532
19772884
20637823
28049043
28108177
29626562
 		CTD
14Hyperglycemia20558911CTD
15Hyperplasia10951269CTD
16Hypertrophy12727805
20614104		CTD
17Insulin Resistance16306350CTD
18Lipid Metabolism Disorders20614104CTD
19Liver Cirrhosis, Experimental15474484CTD
20Liver Neoplasms, Experimental728341
8055661
12727805		CTD
21Liver neoplasms

View details

15890375
16377806
20007298
25058030
28108177
 		CTD
22Massive Hepatic Necrosis17962186CTD
23Myocardial Infarction12087064
19151258		CTD
24Myocardial Reperfusion Injury16411023CTD
25Necrosis17483499CTD
26Neoplasms17405874CTD
27Non-alcoholic Fatty Liver Disease28049043CTD
28Obesity20558911CTD
29Precancerous Conditions1973356CTD
30Reperfusion Injury19058328CTD
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