MetaADEDB 2.0 @ LMMD
Gliclazide
(BOVGTQGAOIONJV-UHFFFAOYSA-N)
Structure
SMILES
O=C(NS(=O)(=O)c1ccc(cc1)C)NN1CC2C(C1)CCC2
Type(s)
Approved
ATC code(s)
A10BB09
Molecular Formula:
C15H21N3O3S
Molecular Weight:
323.411
Log P:
3.4303
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
86.89
CAS Number(s):
21187-98-4
Synonym(s)
1.
Gliclazide
2.
Diabrezide
3.
Diaglyk
4.
Diaikron
5.
Diamicron
6.
Gen-Gliclazide
7.
Gliklazid
8.
Glyade
9.
Glyclazide
10.
Novo-Gliclazide
11.
S-1702
12.
S-852
13.
Gen Gliclazide
14.
Novo Gliclazide
15.
S 1702
16.
S 852
17.
S1702
18.
S852
External Link(s)
MeSHD005907
PubChem Compound3475
BindingDB50103512
ChEBI31654
CHEMBLCHEMBL427216
DrugBankDB01120
DrugCentral1299
KEGGdr:D01599
Therapeutic Target DatabaseD0M2MR
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Anaphylactoid ReactionFAERS: 1US FAERS
2Respiratory FailureFAERS: 1US FAERS
3Abdominal PainCanada Vigilance: 2Canada Vigilance
SIDER
4Abdominal discomfortSIDER
5Abdominal rigidityOFFSIDES
6Abdominal tendernessOFFSIDES
7Abnormal visionSIDER
8AcidosisOFFSIDES
9Acute Coronary SyndromeSIDER
10Acute glomerulonephritisOFFSIDES
11Acute myocardial infarctionOFFSIDES
12AgitationSIDER
13AgranulocytosisSIDER
14AlbuminuriaSIDER
15Alcohol IntoleranceSIDER
16Alcohol abuseSIDER
17Alkaline phosphatase serum increasedSIDER
18AlveolitisOFFSIDES
19Anal FissureSIDER
20Angina PectorisSIDER
21AngioedemaSIDER
22AnorexiaOFFSIDES
23Anti-neutrophil cytoplasmic antibody positive vasculitisOFFSIDES
24AnxietySIDER
25ApathyOFFSIDES
26Aphasia11592575CTD
SIDER
27ArteritisSIDER
28ArthralgiaSIDER
29ArthritisSIDER
30ArthropathySIDER
31AstheniaSIDER
32AsthmaSIDER
33AutomatismOFFSIDES
34Azotemia8061394CTD
35Back PainSIDER
36Bacterial corneal ulcerOFFSIDES
37BalanoposthitisSIDER
38Bladder painSIDER
39Blood alkaline phosphatase increasedSIDER
40Blood and lymphatic system disordersSIDER
41Blood chloride increasedOFFSIDES
42Blood creatinine increasedOFFSIDES
43Blood glucose abnormalOFFSIDES
44Blood glucose decreasedCanada Vigilance: 1Canada Vigilance
OFFSIDES
45Blood glucose increasedCanada Vigilance: 2Canada Vigilance
46Blood lactate dehydrogenase increasedOFFSIDES
47Blood pH decreasedOFFSIDES
48Blood potassium increasedOFFSIDES
49Blood sodiumOFFSIDES
50Blood triglycerides increasedOFFSIDES
SIDER
51Blood urea abnormalOFFSIDES
52Blood urea increasedOFFSIDES
SIDER
53Blood uric acidOFFSIDES
54Bone painSIDER
55BradycardiaSIDER
56BronchitisSIDER
57BronchopneumoniaOFFSIDES
58BursitisSIDER
59Candida endophthalmitisOFFSIDES
60CarcinomaSIDER
61Cardiac FlutterOFFSIDES
62Carpal Tunnel SyndromeSIDER
63CataractSIDER
64Cerebrovascular InsufficiencySIDER
65Cerebrovascular accidentSIDER
66Chemical and Drug Induced Liver Injury10656221
12018908
24085192		CTD
67Chest PainCanada Vigilance: 1Canada Vigilance
SIDER
68Chest discomfortCanada Vigilance: 1Canada Vigilance
69ChillsSIDER
70CholangiolitisOFFSIDES
71CholestasisSIDER
72Choroidal dystrophyOFFSIDES
73Chronic left ventricular failureOFFSIDES
74Cold sweatSIDER
75ColitisSIDER
76Colon adenomaOFFSIDES
77Conjunctival depositOFFSIDES
78ConjunctivitisSIDER
79ConstipationSIDER
80Coronary Artery DiseaseSIDER
81Coronary heart diseaseSIDER
82CystitisSIDER
83DeafnessSIDER
84DehydrationOFFSIDES
85DeliriumSIDER
86Depressed Level of ConsciousnessOFFSIDES
87DermatitisSIDER
88DiabetesOFFSIDES
89Diabetes Mellitus, Experimental20307516
20643114
21439372		CTD
90Diabetes Mellitus14871415CTD
91Diabetes mellitus inadequate controlCanada Vigilance: 1Canada Vigilance
OFFSIDES
92Diastolic dysfunctionOFFSIDES
93DiplopiaSIDER
94DiscomfortSIDER
95Disseminated Intravascular CoagulationOFFSIDES
96Disulfiram like reactionSIDER
97Diverticular perforationOFFSIDES
98DizzinessCanada Vigilance: 1Canada Vigilance
SIDER
99DrowsinessSIDER
100Drug ineffectiveCanada Vigilance: 3Canada Vigilance
101Drug resistanceOFFSIDES
102Dry skinCanada Vigilance: 1Canada Vigilance
SIDER
103Duodenal UlcerOFFSIDES
SIDER
104DyspepsiaSIDER
105EczemaOFFSIDES
SIDER
106Edema8061394CTD
107Epigastric discomfortSIDER
108Epigastric fullnessSIDER
109EpistaxisSIDER
110Erectile dysfunctionSIDER
111Erythema MultiformeSIDER
112ErythemaCanada Vigilance: 1Canada Vigilance
SIDER
113ErythropeniaSIDER
114Eye RednessOFFSIDES
115FatigueSIDER
116Feeling ColdOFFSIDES
SIDER
117Feeling abnormalSIDER
118FlatulenceSIDER
119FlushingSIDER
120Foreign body traumaOFFSIDES
121Gastric Antral Vascular EctasiaOFFSIDES
122Gastric irritationSIDER
123GastritisSIDER
124GastroenteritisSIDER
125Gastrointestinal PainSIDER
126Gastrointestinal infectionOFFSIDES
127Gaze palsyOFFSIDES
128General physical health deteriorationOFFSIDES
129GlaucomaSIDER
130GlycosuriaSIDER
131GoiterOFFSIDES
132GoutSIDER
133GranulomaOFFSIDES
134HeadacheCanada Vigilance: 1Canada Vigilance
SIDER
135Heart valve calcificationOFFSIDES
136HeartburnSIDER
137Hemiplegia11592575CTD
138Hepatitis11592575CTD
SIDER
139HepatomegalySIDER
140HungerSIDER
141Hyperglycemia18380531
28330423		CTD
142Hyperinsulinism18380531CTD
143HyperkeratosisSIDER
144HyperparathyroidismOFFSIDES
145HypersensitivitySIDER
146Hypoglycaemic episodeSIDER
147HypopituitarismSIDER
148HypopyonOFFSIDES
149HypotensionSIDER
150HypothyroidismSIDER
151Iatrogenic injuryOFFSIDES
152Infection in an immunocompromised hostOFFSIDES
153InfectionSIDER
154Inflicted injurySIDER
155Insulin Resistance21439372CTD
156Intestinal ObstructionOFFSIDES
157IritisOFFSIDES
158Kidney FailureOFFSIDES
159Lacrimation abnormal NOSSIDER
160LassitudeSIDER
161Left Ventricular HypertrophyOFFSIDES
162Leg edemaSIDER
163LethargyOFFSIDES
164Leukocytoclastic vasculitisSIDER
165LeukopeniaSIDER
166MalaiseCanada Vigilance: 1Canada Vigilance
SIDER
167MalnutritionSIDER
168MastitisSIDER
169Mental impairmentOFFSIDES
170Metabolic acidosisOFFSIDES
171Mixed hepatocellular-cholestatic injuryOFFSIDES
172Musculoskeletal discomfortSIDER
173MyalgiaSIDER
174Mycosis FungoidesOFFSIDES
175MyelodysplasiaOFFSIDES
176Myocardial Infarction18697569CTD
SIDER
177NauseaCanada Vigilance: 1Canada Vigilance
SIDER
178NephrolithiasisSIDER
179NervousnessSIDER
180NeuralgiaSIDER
181NeuropathySIDER
182NocturiaSIDER
183NumbnessSIDER
184Oliguria8061394CTD
OFFSIDES
185OnychomycosisSIDER
186OrthopneaOFFSIDES
187Otitis MediaSIDER
188OverdoseOFFSIDES
189PainCanada Vigilance: 1Canada Vigilance
SIDER
190Pallor of skinSIDER
191PallorOFFSIDES
SIDER
192PalpitationsSIDER
193PancytopeniaSIDER
194ParanoiaOFFSIDES
195ParaparesisOFFSIDES
196ParaplegiaOFFSIDES
197ParesisSIDER
198PharyngitisSIDER
199Platelet count abnormalOFFSIDES
200PneumoniaSIDER
201PolyuriaSIDER
202Poor quality sleepOFFSIDES
203Porphyria Cutanea TardaSIDER
204Porphyria non-acuteSIDER
205Product substitution issueCanada Vigilance: 4Canada Vigilance
206PruritusCanada Vigilance: 3Canada Vigilance
SIDER
207PsoriasisOFFSIDES
208Punctate keratitisOFFSIDES
209Pyroglutamate increasedOFFSIDES
210PyuriaOFFSIDES
211Reaction gastrointestinalSIDER
212Renal cystSIDER
213Renal tubular disorderOFFSIDES
214Retinal Vein OcclusionOFFSIDES
215RhinitisSIDER
216Salmonella sepsisOFFSIDES
217Secondary hypothyroidismOFFSIDES
218Septic ShockOFFSIDES
219Shallow breathingSIDER
220SinusitisSIDER
221Skin UlcerSIDER
222Skin hypertrophyCanada Vigilance: 1Canada Vigilance
223SomnolenceSIDER
224Stevens-Johnson SyndromeSIDER
225Sudden deathOFFSIDES
226Superficial ThrombophlebitisOFFSIDES
227SweatingSIDER
228SwellingCanada Vigilance: 1Canada Vigilance
229TachycardiaSIDER
230Tardive DyskinesiaOFFSIDES
231TensionSIDER
232Therapeutic response changedCanada Vigilance: 3Canada Vigilance
233ThirstSIDER
234ThrombocytopeniaSIDER
235ThrombophlebitisSIDER
236TinnitusSIDER
237ToothacheSIDER
238Toxic Epidermal NecrolysisSIDER
239TracheitisSIDER
240TremblingSIDER
241TremorSIDER
242Upset stomachSIDER
243Urinary tract infectionSIDER
244Urine output increasedOFFSIDES
SIDER
245UrticariaSIDER
246Visual ImpairmentSIDER
247Visual disturbanceSIDER
248Vitreous DetachmentOFFSIDES
249VomitingCanada Vigilance: 1Canada Vigilance
SIDER
250XerophthalmiaSIDER
251fibromaOFFSIDES
252jaundiceSIDER
253nervous system disorderSIDER
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