MetaADEDB 2.0 @ LMMD
Indapamide
(NDDAHWYSQHTHNT-UHFFFAOYSA-N)
Structure
SMILES
CC1Cc2c(N1NC(=O)c1ccc(c(c1)S(=O)(=O)N)Cl)cccc2
Type(s)
Approved
ATC code(s)
C03BA11; C09BX01; C10BX13; G01AE10
Molecular Formula:
C16H16ClN3O3S
Molecular Weight:
365.835
Log P:
4.3204
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
100.88
CAS Number(s):
26807-65-8
Synonym(s)
1.
Indapamide
2.
Metindamide
3.
S-1520
4.
SE-1520
5.
S 1520
6.
S1520
7.
SE 1520
8.
SE1520
External Link(s)
MeSHD007190
PubChem Compound3702
BindingDB25901
ChEBI5893
CHEMBLCHEMBL406
DrugBankDB00808
DrugCentral1433
IUPHAR/BPS Guide to PHARMACOLOGY7203
KEGGdr:D00345
Therapeutic Target DatabaseD0H8FH
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AstheniaFAERS: 14OFFSIDES
SIDER
US FAERS
2DizzinessFAERS: 13
Canada Vigilance: 2		6342786
12654706
15840731		CTD
SIDER
Canada Vigilance
US FAERS
3RhabdomyolysisFAERS: 11SIDER
US FAERS
4Cardiac ArrestFAERS: 10US FAERS
5MalaiseFAERS: 10SIDER
US FAERS
6SyncopeFAERS: 912380780CTD
SIDER
US FAERS
7Long QT SyndromeFAERS: 81705875
18507554		CTD
US FAERS
8Acute kidney injuryFAERS: 7US FAERS
9Feeling abnormalFAERS: 7SIDER
US FAERS
10Blood creatine phosphokinase increasedFAERS: 6US FAERS
11HeadacheFAERS: 6
Canada Vigilance: 2		6342786CTD
SIDER
Canada Vigilance
US FAERS
12AsthmaFAERS: 5OFFSIDES
SIDER
US FAERS
13Atrial FibrillationFAERS: 5SIDER
US FAERS
14Metabolic alkalosisFAERS: 5SIDER
US FAERS
15AlveolitisFAERS: 4US FAERS
16DehydrationFAERS: 4OFFSIDES
SIDER
US FAERS
17GastroenteritisFAERS: 4SIDER
US FAERS
18HypotensionFAERS: 43025980
4094184		CTD
SIDER
US FAERS
19Left Ventricular HypertrophyFAERS: 4US FAERS
20PemphigusFAERS: 4US FAERS
21Angina PectorisFAERS: 3SIDER
US FAERS
22Blood potassium decreasedFAERS: 3OFFSIDES
US FAERS
23Blood sodium decreasedFAERS: 3US FAERS
24DyspepsiaFAERS: 3
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
25DysuriaFAERS: 3OFFSIDES
SIDER
US FAERS
26Memory impairmentFAERS: 3US FAERS
27MyalgiaFAERS: 3SIDER
US FAERS
28MyopathyFAERS: 3SIDER
US FAERS
29VomitingFAERS: 3
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
30Altered state of consciousnessFAERS: 2US FAERS
31AmnesiaFAERS: 2OFFSIDES
SIDER
US FAERS
32Back PainFAERS: 2SIDER
US FAERS
33Blood glucose fluctuationFAERS: 2US FAERS
34Diabetes MellitusFAERS: 219483504CTD
SIDER
US FAERS
35Duodenal UlcerFAERS: 2US FAERS
36ErythemaFAERS: 2SIDER
US FAERS
37FatigueFAERS: 215840731CTD
SIDER
US FAERS
38HypersensitivityFAERS: 2SIDER
US FAERS
39Medication ErrorFAERS: 2US FAERS
40Muscle CrampFAERS: 2US FAERS
41Musculoskeletal stiffnessFAERS: 2US FAERS
42Myoglobin urine presentFAERS: 2US FAERS
43NauseaFAERS: 2
Canada Vigilance: 5		Canada Vigilance
OFFSIDES
SIDER
US FAERS
44NeuralgiaFAERS: 2US FAERS
45PainFAERS: 2SIDER
US FAERS
46PalpitationsFAERS: 2SIDER
US FAERS
47PneumoniaFAERS: 2SIDER
US FAERS
48SinusitisFAERS: 2OFFSIDES
SIDER
US FAERS
49Transaminases increasedFAERS: 2OFFSIDES
US FAERS
50Ventricular arrhythmiaFAERS: 2SIDER
US FAERS
51jaundiceFAERS: 211177350CTD
SIDER
US FAERS
52Abdominal PainFAERS: 1
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
SIDER
US FAERS
53Acute Coronary SyndromeFAERS: 1US FAERS
54Aldolase increasedFAERS: 1US FAERS
55AngioedemaFAERS: 1OFFSIDES
SIDER
US FAERS
56Biliary FistulaFAERS: 1US FAERS
57Blood creatinine increasedFAERS: 1OFFSIDES
US FAERS
58Blood glucose increasedFAERS: 1SIDER
US FAERS
59Blood magnesium decreasedFAERS: 1OFFSIDES
US FAERS
60Blood potassium increasedFAERS: 1OFFSIDES
US FAERS
61Blood pressure fluctuationFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
62Blood urea increasedFAERS: 1OFFSIDES
SIDER
US FAERS
63BradycardiaFAERS: 122744888CTD
OFFSIDES
US FAERS
64CellulitisFAERS: 1US FAERS
65Cerebrovascular accidentFAERS: 1SIDER
US FAERS
66Chest discomfortFAERS: 1US FAERS
67Choroidal DetachmentFAERS: 1US FAERS
68Coombs test positiveFAERS: 1US FAERS
69Drug dispensing errorFAERS: 1US FAERS
70DysarthriaFAERS: 1US FAERS
71DysgeusiaFAERS: 1
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
72Erythema MultiformeFAERS: 1SIDER
US FAERS
73GoutFAERS: 1SIDER
US FAERS
74HyperaldosteronismFAERS: 1US FAERS
75HypocalciuriaFAERS: 1US FAERS
76HyporeflexiaFAERS: 1US FAERS
77IleusFAERS: 1US FAERS
78Incorrect dose administeredFAERS: 1US FAERS
79Intercepted medication errorFAERS: 1US FAERS
80LacerationFAERS: 1US FAERS
81LethargyFAERS: 1SIDER
US FAERS
82LeukopeniaFAERS: 1SIDER
US FAERS
83Lower respiratory tract infectionFAERS: 1US FAERS
84Myoglobin blood increasedFAERS: 1US FAERS
85NeutropeniaFAERS: 1US FAERS
86No adverse eventFAERS: 1US FAERS
87Oropharyngeal painFAERS: 1US FAERS
88Osmotic demyelination syndromeFAERS: 1US FAERS
89PresyncopeFAERS: 1US FAERS
90PruritusFAERS: 111177350CTD
SIDER
US FAERS
91Reaction to drug excipientsFAERS: 1US FAERS
92Reaction to excipientFAERS: 1US FAERS
93Renal painFAERS: 1SIDER
US FAERS
94Respiratory tract infection bacterialFAERS: 1US FAERS
95Reticulocyte count increasedFAERS: 1US FAERS
96SomnolenceFAERS: 1SIDER
US FAERS
97Stevens-Johnson SyndromeFAERS: 125811541CTD
SIDER
US FAERS
98Stress ulcerFAERS: 1US FAERS
99Sudden Cardiac DeathFAERS: 1US FAERS
100TachycardiaFAERS: 1SIDER
US FAERS
101Toxic Epidermal NecrolysisFAERS: 1SIDER
US FAERS
102Urinary IncontinenceFAERS: 1US FAERS
103Urinary tract infectionFAERS: 1SIDER
US FAERS
104UrticariaFAERS: 1SIDER
US FAERS
105Ventricular FlutterFAERS: 1US FAERS
106Ventricular hypertrophyFAERS: 1US FAERS
107Visual ImpairmentFAERS: 1SIDER
US FAERS
108Vitamin D DeficiencyFAERS: 1US FAERS
109Weight decreasedFAERS: 1SIDER
US FAERS
110Abdominal discomfortCanada Vigilance: 1Canada Vigilance
OFFSIDES
111Abdominal tendernessOFFSIDES
112Acute tonsillitisOFFSIDES
113AgitationSIDER
114AgranulocytosisSIDER
115Albuminuria

View details

1927891
12654706
15257186
17198918
 		CTD
116AlveoloplastyOFFSIDES
117AmblyopiaSIDER
118AmphetaminesOFFSIDES
119Anaphylactic shockSIDER
120AnhidrosisOFFSIDES
121AnorexiaOFFSIDES
SIDER
122Anticonvulsant drug level increasedOFFSIDES
123AnxietyCanada Vigilance: 1Canada Vigilance
OFFSIDES
SIDER
124Aortic valve sclerosisOFFSIDES
125ApathyOFFSIDES
126AppendicitisOFFSIDES
127Application site reactionSIDER
128ArthralgiaSIDER
129ArthritisSIDER
130ArthropathySIDER
131AtaxiaSIDER
132Atrial FlutterSIDER
133Bacteria tissue specimen identifiedOFFSIDES
134Bacterial test positiveOFFSIDES
135Beta 2 microglobulin increasedOFFSIDES
136Bladder painSIDER
137Blood GlucoseOFFSIDES
138Blood albumin increasedOFFSIDES
139Blood alkaline phosphatase increasedOFFSIDES
140Blood chloride decreasedOFFSIDES
141Blood growth hormone increasedOFFSIDES
142Blood iron increasedOFFSIDES
143Blood lactate dehydrogenase increasedOFFSIDES
144Blood magnesium increasedOFFSIDES
145Blood sodiumOFFSIDES
146Blood thyroid stimulating hormoneOFFSIDES
147Blood uric acidOFFSIDES
148Bone painSIDER
149Bone swellingOFFSIDES
150Bone trimmingOFFSIDES
151Brain Ischemia2184650CTD
152BronchiectasisOFFSIDES
153BronchitisSIDER
154Bullous eruptionSIDER
155CarcinomaSIDER
156Cardiac stress test abnormalOFFSIDES
157Cataract operationOFFSIDES
158Cataract operation complicationOFFSIDES
159CataractSIDER
160Catheter site painOFFSIDES
161Catheter site swellingOFFSIDES
162Cell DeathOFFSIDES
163Chest PainOFFSIDES
SIDER
164Choking sensationOFFSIDES
165CholangiolitisOFFSIDES
166Cholelithiasis11177350CTD
167ConfabulationOFFSIDES
168ConjunctivitisSIDER
169ConstipationSIDER
170CystitisSIDER
171Cytolytic hepatitisOFFSIDES
172Dental examinationOFFSIDES
173Denture wearerOFFSIDES
174DermatitisSIDER
175DiabetesOFFSIDES
176Diabetic NephropathyOFFSIDES
177Diabetic RetinopathyOFFSIDES
178DiarrheaOFFSIDES
179Diastolic dysfunctionOFFSIDES
180DiplopiaOFFSIDES
181DiscomfortSIDER
182Disturbance in sexual arousalSIDER
183DrowsinessSIDER
184Drug effect delayedOFFSIDES
185Drug ineffectiveCanada Vigilance: 1Canada Vigilance
186Drug toxicityOFFSIDES
187DuodenectomyOFFSIDES
188DuodenitisSIDER
189EcchymosisSIDER
190Edema6869205CTD
191Electrocardiogram U wave presentSIDER
192Electrocardiogram U-wave abnormalitySIDER
193Electrolyte imbalanceSIDER
194Electromechanical dissociationOFFSIDES
195Embolic cerebral infarctionOFFSIDES
196Eosinophilia11177350CTD
197Epidural lipomatosisOFFSIDES
198Epigastric discomfortSIDER
199EpistaxisOFFSIDES
200Erectile dysfunctionSIDER
201Escherichia urinary tract infectionOFFSIDES
202Feeling ColdOFFSIDES
203Femoral pulse decreasedOFFSIDES
204Flank PainOFFSIDES
205FlatulenceSIDER
206Fluid overloadOFFSIDES
207FlushingSIDER
208FractureSIDER
209Gastric irritationSIDER
210GastritisSIDER
211Gastrointestinal PainSIDER
212Gastrointestinal motility disorderOFFSIDES
213Glasgow coma scaleOFFSIDES
214GlycosuriaSIDER
215Haptoglobin DecreasedOFFSIDES
216HemiparesisOFFSIDES
217Heparin-induced thrombocytopeniaOFFSIDES
218Hepatic EncephalopathySIDER
219Hepatic InsufficiencySIDER
220Hepatitis B positiveOFFSIDES
221HepatitisSIDER
222HerniaSIDER
223Hyaluronic acid increasedOFFSIDES
224Hypercalciuria15840731CTD
225Hyperglycemia1853463CTD
226Hypokalemia

View details

673684
693289
724465
1705875
1853463
1998577
2216949
2711019
3047887
4017458
4053543
6237845
6346846
6802373
6869205
8573958
9867313
11999238
12088485
12380780
18386633
18507554
 		CTD
227Hyponatremia

View details

8573958
11999238
12088485
18386633
18507554
 		CTD
228InfectionSIDER
229InfluenzaSIDER
230Infusion site mobility decreasedOFFSIDES
231Injection site massOFFSIDES
232Injection site warmthOFFSIDES
233Intervertebral disc disorderOFFSIDES
234Intestinal PerforationOFFSIDES
235Joint injuryOFFSIDES
236Kidney Diseases19483504CTD
237Kidney FailureOFFSIDES
238Labile hypertensionOFFSIDES
239Large intestine perforationOFFSIDES
240LaryngitisSIDER
241LightheadednessSIDER
242Limb injuryOFFSIDES
243Listeria sepsisOFFSIDES
244Lithium toxicitySIDER
245MalnutritionSIDER
246Meniere Disease1998577CTD
247Mixed liver injuryOFFSIDES
248Multiple allergiesOFFSIDES
249Muscle Weakness6342786CTD
250Musculoskeletal discomfortSIDER
251MyopiaSIDER
252NasopharyngitisSIDER
253Necrolysis epidermalSIDER
254Necrosis16556441CTD
255Nephritis, Interstitial2369678CTD
256NephroangiosclerosisOFFSIDES
257NervousnessCanada Vigilance: 1Canada Vigilance
SIDER
258Nipple painOFFSIDES
259NocturiaSIDER
260Non-cardiac chest painOFFSIDES
261Numbness of limbsSIDER
262Ocular vascular disorderOFFSIDES
263OliguriaSIDER
264Optic Disc EdemaOFFSIDES
265Optic NeuritisSIDER
266Oral candidiasisSIDER
267Oral fungal infectionOFFSIDES
268Oral infectionOFFSIDES
269OrthopneaOFFSIDES
270OsteomyelitisOFFSIDES
271OsteoporosisOFFSIDES
272OsteoradionecrosisOFFSIDES
273OsteosclerosisOFFSIDES
274Pancreatic InsufficiencyOFFSIDES
275PancreatitisOFFSIDES
SIDER
276Pancytopenia7519541CTD
277Peripheral swellingCanada Vigilance: 1Canada Vigilance
278PeritonitisOFFSIDES
279PharyngitisSIDER
280PhotophobiaSIDER
281PolyuriaOFFSIDES
SIDER
282Poor dental conditionOFFSIDES
283Post procedural strokeOFFSIDES
284ProctitisSIDER
285Product substitution issueCanada Vigilance: 3Canada Vigilance
286Productive CoughOFFSIDES
287Pulmonary HypertensionOFFSIDES
288PurpuraSIDER
289Respiratory distressSIDER
290Respiratory tract congestionOFFSIDES
291RhinitisSIDER
292RhonchiOFFSIDES
293Scleroderma renal crisisOFFSIDES
294ScotomaOFFSIDES
295Serum urea increasedSIDER
296ShockSIDER
297Sick Sinus SyndromeOFFSIDES
298Sinus bradycardiaOFFSIDES
SIDER
299Sjogren's SyndromeOFFSIDES
300Skin lacerationOFFSIDES
301Skin necrosisOFFSIDES
302Skin noduleSIDER
303Sleep Wake Disorders3277419CTD
304Spinal column stenosisOFFSIDES
305Spinal fusion surgeryOFFSIDES
306Stomach acheSIDER
307StomatitisSIDER
308StressOFFSIDES
309Subcutaneous EmphysemaOFFSIDES
310Subcutaneous noduleOFFSIDES
311Supraventricular tachycardiaSIDER
312SweatingSIDER
313TensionSIDER
314ThrombocytopeniaSIDER
315Tingling of extremitySIDER
316TinnitusSIDER
317Tooth ExtractionOFFSIDES
318Torsades de Pointes1705875
16260053		CTD
319Toxicity to various agentsSIDER
320Transferrin saturation increasedOFFSIDES
321Tricuspid valve sclerosisOFFSIDES
322Troponin increasedOFFSIDES
323Urinary Calculi15840731CTD
324Urine flow decreasedOFFSIDES
325Urine output increasedSIDER
326Vascular purpuraSIDER
327VasculitisSIDER
328Vasodilation procedureSIDER
329VasodilationSIDER
330Ventricular Fibrillation1705875CTD
331Ventricular hypokinesiaOFFSIDES
332VertigoSIDER
333Visual disturbanceSIDER
334Wound InfectionOFFSIDES
335Wound dehiscenceOFFSIDES
336Wound infection staphylococcalOFFSIDES
337XanthopsiaSIDER
338nervous system disorderSIDER
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