alvocidib
(BIIVYFLTOXDAOV-YVEFUNNKSA-N)
Structure
- SMILES
- CN1CC[C@@H]([C@@H](C1)O)c1c(O)cc(c2c1oc(cc2=O)c1ccccc1Cl)O
- Type(s)
- Experimental; Investigational
- Molecular Formula:
- C21H20ClNO5
- Molecular Weight:
- 401.840
- Log P:
- 3.2425
- Hydrogen Bond Acceptor:
- 6
- Hydrogen Bond Donor:
- 3
- TPSA:
- 94.14
- CAS Number(s):
- 131740-09-5; 146426-40-6
Synonym(s)
1.
alvocidib
2.
(-)cis-5,7-dihydroxy-2-(2-chlorophenyl)-8-(4-(3-hydroxy-1-methyl)piperidinyl)-4H-1-benzopyran-4-one
3.
HMR 1275
4.
L 868275
5.
L-868275
6.
L86-8275
7.
flavopiridol
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Anemia | 12881391 | CTD | |
| 2 | Anorexia | 12881391 | CTD | |
| 3 | Colonic Neoplasms | 14676132 | CTD | |
| 4 | Diarrhea | 12881391 | CTD | |
| 5 | Esophageal Neoplasms | 16905211 | CTD | |
| 6 | Fatigue | 12881391 | CTD | |
| 7 | Head and Neck Neoplasms | 9802881 | CTD | |
| 8 | Hyperbilirubinemia | 21239698 | CTD | |
| 9 | Hyperglycemia | 12881391 | CTD | |
| 10 | Hyperkalemia | 17906454 | CTD | |
| 11 | Lymphoma, AIDS-Related | 9516149 | CTD | |
| 12 | Nausea | 12881391 19934304 | CTD | |
| 13 | Neointima | 10441105 15180955 | CTD | |
| 14 | Neoplasm Metastasis | 16921509 | CTD | |
| 15 | Neoplasms, Experimental | 11751522 | CTD | |
| 16 | Neoplasms | 12734434 19934304 | CTD | |
| 17 | Neutropenia | 19934304 | CTD | |
| 18 | Prostatic Neoplasms | 16921509 | CTD | |
| 19 | Stomach Neoplasms | 14676132 | CTD | |
| 20 | Tumor Lysis Syndrome | 17906454 21239698 | CTD | |
| 21 | Vomiting | 12881391 19934304 | CTD | |
| 22 | leukemia | 15039284 | CTD |
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