MetaADEDB 2.0 @ LMMD
Capsaicin
(YKPUWZUDDOIDPM-SOFGYWHQSA-N)
Structure
SMILES
COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O
Type(s)
Approved
ATC code(s)
M02AB01; N01BX04
Molecular Formula:
C18H27NO3
Molecular Weight:
305.412
Log P:
4.1805
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
58.56
CAS Number(s):
404-86-4
Synonym(s)
1.
Capsaicin
2.
8-Methyl-N-Vanillyl-6-Nonenamide
3.
Antiphlogistine Rub A-535 Capsaicin
4.
Axsain
5.
Capsaicine
6.
Capsicum Farmaya
7.
Capsidol
8.
Capsin
9.
Capzasin
10.
Gelcen
11.
Katrum
12.
NGX-4010
13.
Zacin
14.
Zostrix
15.
8 Methyl N Vanillyl 6 Nonenamide
16.
NGX 4010
17.
NGX4010
External Link(s)
MeSHD002211
PubChem Compound1548943
BindingDB86537
20461
ChEBI3374
94524
CHEMBLCHEMBL294199
DrugBankDB06774
DrugCentral3064
IUPHAR/BPS Guide to PHARMACOLOGY2486
KEGGcpd:C06866
dr:D00250
Therapeutic Target DatabaseD0U5CE
ZINC1530575
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Application site painFAERS: 58SIDER
US FAERS
2PainFAERS: 33

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CTD
US FAERS
3Application site erythemaFAERS: 31SIDER
US FAERS
4Occupational exposure to productFAERS: 28US FAERS
5Application site burnFAERS: 26SIDER
US FAERS
6ErythemaFAERS: 24
Canada Vigilance: 1
1711752CTD
SIDER
Canada Vigilance
US FAERS
7HypersensitivityFAERS: 18
Canada Vigilance: 1
11160071CTD
Canada Vigilance
US FAERS
8Application site vesiclesFAERS: 17SIDER
US FAERS
9Throat irritationFAERS: 17SIDER
US FAERS
10Drug ineffectiveFAERS: 16US FAERS
11Burning sensationFAERS: 13SIDER
US FAERS
12Thermal burnFAERS: 13US FAERS
13Intentional product misuseFAERS: 9US FAERS
14PruritusFAERS: 89705161CTD
SIDER
US FAERS
15GlossitisFAERS: 7US FAERS
16Accidental exposure to productFAERS: 6US FAERS
17Drug administration errorFAERS: 5US FAERS
18NeuralgiaFAERS: 520400377CTD
US FAERS
19PneumoniaFAERS: 522575871CTD
US FAERS
20Application site swellingFAERS: 4SIDER
US FAERS
21Application site warmthFAERS: 4SIDER
US FAERS
22Chest PainFAERS: 4US FAERS
23DysphoniaFAERS: 4US FAERS
24Incorrect drug administration durationFAERS: 4OFFSIDES
US FAERS
25MalaiseFAERS: 4US FAERS
26NauseaFAERS: 4OFFSIDES
SIDER
US FAERS
27Product quality issueFAERS: 4US FAERS
28RhinitisFAERS: 419672097CTD
US FAERS
29Application site ulcerFAERS: 3US FAERS
30BradycardiaFAERS: 3

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CTD
OFFSIDES
US FAERS
31BronchospasmFAERS: 3US FAERS
32Chest discomfortFAERS: 3US FAERS
33DiscomfortFAERS: 3US FAERS
34Disease ProgressionFAERS: 3US FAERS
35DizzinessFAERS: 3OFFSIDES
SIDER
US FAERS
36DysgeusiaFAERS: 3SIDER
US FAERS
37HypotensionFAERS: 3

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CTD
US FAERS
38Inappropriate schedule of drug administrationFAERS: 3US FAERS
39Incorrect product storageFAERS: 3US FAERS
40InflammationFAERS: 3

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CTD
US FAERS
41Malignant neoplasm progressionFAERS: 3US FAERS
42Product use issueFAERS: 3US FAERS
43Accidental exposureFAERS: 2US FAERS
44Application site erosionFAERS: 2SIDER
US FAERS
45Application site rashFAERS: 2SIDER
US FAERS
46Application site reactionFAERS: 2SIDER
US FAERS
47Diabetes MellitusFAERS: 2US FAERS
48EpidermolysisFAERS: 2US FAERS
49Eye irritationFAERS: 2SIDER
US FAERS
50General physical health deteriorationFAERS: 2US FAERS
51Hypertensive crisisFAERS: 2US FAERS
52HyperventilationFAERS: 2US FAERS
53HypogeusiaFAERS: 2US FAERS
54Inappropriate schedule of product administrationFAERS: 2US FAERS
55MonoplegiaFAERS: 2US FAERS
56Oral painFAERS: 2US FAERS
57Oral pruritusFAERS: 2US FAERS
58Oropharyngeal painFAERS: 2US FAERS
59Pancreatic carcinomaFAERS: 2US FAERS
60Peripheral swellingFAERS: 2US FAERS
61PresyncopeFAERS: 2US FAERS
62Rash erythematousFAERS: 2US FAERS
63Skin irritationFAERS: 2US FAERS
64StomatitisFAERS: 2US FAERS
65SwellingFAERS: 2US FAERS
66TremorFAERS: 2US FAERS
67Upper respiratory tract irritationFAERS: 2US FAERS
68UrticariaFAERS: 2US FAERS
69VertigoFAERS: 2US FAERS
70VomitingFAERS: 2SIDER
US FAERS
71Wrong technique in product usage processFAERS: 2US FAERS
72AbasiaFAERS: 1US FAERS
73Activities of daily living impairedFAERS: 1US FAERS
74Adverse eventFAERS: 1US FAERS
75AllodyniaFAERS: 1US FAERS
76Anaphylactic shockFAERS: 1US FAERS
77AngerFAERS: 1US FAERS
78Angina PectorisFAERS: 1US FAERS
79AngioedemaFAERS: 1OFFSIDES
US FAERS
80Application site exfoliationFAERS: 1SIDER
US FAERS
81Application site irritationFAERS: 1SIDER
US FAERS
82Application site necrosisFAERS: 1US FAERS
83Application site noduleFAERS: 1US FAERS
84Application site papulesFAERS: 1SIDER
US FAERS
85Application site pruritusFAERS: 1SIDER
US FAERS
86Application site pustulesFAERS: 1US FAERS
87Application site scarFAERS: 1US FAERS
88AstheniaFAERS: 1OFFSIDES
US FAERS
89AsthmaFAERS: 1US FAERS
90Atrial FibrillationFAERS: 1US FAERS
91Back PainFAERS: 1US FAERS
92Benign neoplasm of spinal cordFAERS: 1US FAERS
93Blood pressure fluctuationFAERS: 1US FAERS
94Breast cancer recurrentFAERS: 1US FAERS
95CellulitisFAERS: 1US FAERS
96Chemical burn of respiratory tractFAERS: 1US FAERS
97Chemical burn of skinFAERS: 1US FAERS
98Chemical injuryFAERS: 1US FAERS
99ChillsFAERS: 1US FAERS
100CryingFAERS: 1US FAERS
101DeafnessFAERS: 1US FAERS
102Disease recurrenceFAERS: 1US FAERS
103Drug effect incompleteFAERS: 1US FAERS
104Drug prescribing errorFAERS: 1US FAERS
105Emotional distressFAERS: 1US FAERS
106ErysipelasFAERS: 1US FAERS
107Eye painFAERS: 1SIDER
US FAERS
108Feeling ColdFAERS: 1US FAERS
109Feeling abnormalFAERS: 1US FAERS
110FormicationFAERS: 1US FAERS
111FrostbiteFAERS: 1US FAERS
112Gait inabilityFAERS: 1US FAERS
113Genital rashFAERS: 1US FAERS
114Guillain-Barre SyndromeFAERS: 1US FAERS
115HeadacheFAERS: 120054487CTD
SIDER
US FAERS
116House dust allergyFAERS: 1US FAERS
117InfectionFAERS: 1SIDER
US FAERS
118Intercepted medication errorFAERS: 1US FAERS
119Intracranial AneurysmFAERS: 1US FAERS
120Joint Range of Motion DecreasedFAERS: 1US FAERS
121Joint swellingFAERS: 1US FAERS
122Loss of personal independence in daily activitiesFAERS: 1US FAERS
123Lung hyperinflationFAERS: 1US FAERS
124Maternal exposure during breast feedingFAERS: 1US FAERS
125Metastatic NeoplasmFAERS: 1US FAERS
126Musculoskeletal PainFAERS: 1US FAERS
127Musculoskeletal stiffnessFAERS: 1US FAERS
128Myocardial InfarctionFAERS: 120098047CTD
US FAERS
129NecrosisFAERS: 110066710
12418083
CTD
US FAERS
130NervousnessFAERS: 1US FAERS
131Oropharyngeal discomfortFAERS: 1US FAERS
132Pain of skinFAERS: 1US FAERS
133PallorFAERS: 1US FAERS
134PalpitationsFAERS: 1SIDER
US FAERS
135PanniculitisFAERS: 1US FAERS
136Peripheral artery thrombosisFAERS: 1US FAERS
137Plantar erythemaFAERS: 1US FAERS
138Product container issueFAERS: 1US FAERS
139Product formulation issueFAERS: 1US FAERS
140Product label confusionFAERS: 1US FAERS
141Product storage errorFAERS: 1US FAERS
142ProteinuriaFAERS: 1US FAERS
143Quality of life decreasedFAERS: 1US FAERS
144Respiratory FailureFAERS: 1US FAERS
145Respiratory distressFAERS: 1US FAERS
146SarcomaFAERS: 1US FAERS
147ScabFAERS: 1US FAERS
148Skin ErosionFAERS: 1US FAERS
149Skin lesionFAERS: 1US FAERS
150Skin reactionFAERS: 1US FAERS
151SomnolenceFAERS: 1US FAERS
152SyncopeFAERS: 1US FAERS
153SyringomyeliaFAERS: 1US FAERS
154TachycardiaFAERS: 11722285
2541852
16051405
CTD
SIDER
US FAERS
155Walking aid userFAERS: 1US FAERS
156Wrong technique in drug usage processFAERS: 1US FAERS
157Abdominal Pain10189853CTD
158Aberrant Crypt Foci29155087CTD
159Abnormalities, Drug-Induced18926900CTD
160Acute kidney injury18460982CTD
161Age indeterminate myocardial infarctionOFFSIDES
162AgraphiaOFFSIDES
163Alopecia17569567CTD
164Anaphylactoid ReactionCanada Vigilance: 2Canada Vigilance
165Anticonvulsant drug level increasedOFFSIDES
166Anxiety Disorders12893632CTD
167Apnea

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CTD
168Application site drynessSIDER
169Application site excoriationSIDER
170Application site inflammationSIDER
171Application site urticariaSIDER
172Arthritis, Experimental7473211CTD
173Asphyxia20441089CTD
174AtelectasisOFFSIDES
175Atherosclerosis21908651
30342015
CTD
176AuraOFFSIDES
177Blood alkaline phosphatase increasedOFFSIDES
178Brain Ischemia19211983CTD
179Bronchial Diseases15774269CTD
180BronchitisOFFSIDES
SIDER
181BronchopneumoniaOFFSIDES
182Cardiac telemetry abnormalOFFSIDES
183Cardiomegaly15496307CTD
184Catheter related complicationOFFSIDES
185Central Nervous System InfectionOFFSIDES
186Cerebral atrophyOFFSIDES
187Cerebrovascular Disorders15009014CTD
188Chemical and Drug Induced Liver Injury29155087CTD
189Chemotherapeutic drug level increasedOFFSIDES
190Choking sensationOFFSIDES
191Chromosome Breakage29155087CTD
192ConfabulationOFFSIDES
193Corneal Diseases12824234CTD
194Corneal Ulcer19553628CTD
195Depressed moodOFFSIDES
196Device malfunctionOFFSIDES
197Diabetes Mellitus, Experimental17241282CTD
198Dissociative disorderOFFSIDES
199Drug Eruptions1371395CTD
200Duodenal Ulcer10671773
11535926
CTD
201DysphemiaOFFSIDES
202Dysthymic DisorderOFFSIDES
203Economic problemOFFSIDES
204Edema

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CTD
205Electrocardiogram QRS complexOFFSIDES
206Emotional disorderOFFSIDES
207EnchondromatosisOFFSIDES
208EpendymomaOFFSIDES
209Epilepsy, Temporal Lobe20144892CTD
210Esophageal Diseases19566590CTD
211Extravasation of Diagnostic and Therapeutic Materials

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CTD
212Facial Pain

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CTD
213Fatty Liver19798065CTD
214Feeding and Eating Disorders20688118CTD
215Fever15862512CTD
216Fluid overloadOFFSIDES
217Glioblastoma18405923CTD
218Hearing Loss20712533CTD
219Heartburn19566590CTD
220Hyperalgesia

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CTD
221Hypercholesterolemia16335782CTD
222Hyperemia

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CTD
223Hyperglycemia1378463CTD
224Hyperplasia10360863
18931146
21268302
CTD
225HypoxiaOFFSIDES
226Inappropriate affectOFFSIDES
227InfestationSIDER
228Instillation site painSIDER
229Laryngeal Edema20441089CTD
230Liver Cirrhosis, Experimental18555214CTD
231Liver diseases16956363CTD
232Liver neoplasms1888447CTD
233Low Back Pain20098047CTD
234Lung Neoplasms1888447CTD
235Lymphocyte count decreasedOFFSIDES
236Mastitis1779253CTD
237Mental status changesOFFSIDES
238Metabolic Diseases21332406CTD
239Movement Disorders2727012
11408034
16806299
CTD
240Multiple Myeloma17505005CTD
241Muscle WeaknessOFFSIDES
242NasopharyngitisOFFSIDES
SIDER
243Neoplasms, Experimental29155087CTD
244Neoplasms14871840CTD
245Nerve Degeneration11275380CTD
246Neurogenic Inflammation

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CTD
247Neuropathy, Painful23747933CTD
248NeuropathySIDER
249Nociceptive Pain23747933
30053451
CTD
250Nocturia8709370CTD
251Nose Diseases21981454CTD
252Obesity

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CTD
253Ocular icterusOFFSIDES
254OverdoseOFFSIDES
255Pain, Referred27899695CTD
256Papilloma20660715CTD
257ParanoiaOFFSIDES
258Paresthesia2458561CTD
259Peripheral Nervous System Diseases11516259CTD
260Pharmaceutical product complaintOFFSIDES
261Plaque, Atherosclerotic30342015CTD
262PneumothoraxOFFSIDES
263Prenatal Exposure Delayed Effects

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CTD
264Prenatal Injuries1378463CTD
265Product substitution issueOFFSIDES
266Prostatic Neoplasms16540674CTD
267Protein total decreasedOFFSIDES
268Reflex, Abnormal

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CTD
269Reperfusion Injury17360009
18460982
19211983
CTD
270Respiration Disorders19090345CTD
271Respiratory Hypersensitivity22575871CTD
272Seizures15037813CTD
273Sensation Disorders8343895CTD
274Sepsis12888332CTD
275SinusitisSIDER
276Skin Neoplasms20660715CTD
277Spinal claudicationOFFSIDES
278Stomach Neoplasms22414649CTD
279Temporomandibular Joint Disorders17997062CTD
280Toxic Optic NeuropathyOFFSIDES
281Trigeminal Neuralgia19004549CTD
282Unevaluable eventOFFSIDES
283Unresponsive to stimuliOFFSIDES
284Urinary Bladder Diseases8032584
8343895
CTD
285Urination Disorders8709370
9343982
CTD
286Uveitis19553628CTD
287Vascular Diseases15298541
15496307
CTD
288Visceral Pain27899695CTD
289Weight Gain19798065
20359164
CTD
290Wheelchair userOFFSIDES
291anaphylaxis20441089CTD
292nervous system disorderSIDER
293prostatitis17141941CTD
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