MetaADEDB 2.0 @ LMMD
telmisartan, hydrochlorothiazide drug combination
(OZCVMXDGSSXWFT-UHFFFAOYSA-N)
Structure
SMILES
Clc1cc2NCNS(=O)(=O)c2cc1S(=O)(=O)N.CCCc1nc2c(n1Cc1ccc(cc1)c1ccccc1C(=O)O)cc(cc2C)c1nc2c(n1C)cccc2
Molecular Formula:
C40H38ClN7O6S2
Molecular Weight:
812.356
Log P:
10.2418
Hydrogen Bond Acceptor:
13
Hydrogen Bond Donor:
4
TPSA:
208.06
CAS Number(s):
485391-74-0
Synonym(s)
1.
telmisartan, hydrochlorothiazide drug combination
2.
Micardis-HCT
3.
telmi-sartan-hydrochlorothiazide
4.
telmisartan-hydrochlorothiazide
External Link(s)
MeSHC436283
PubChem Compound216293
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1DizzinessFAERS: 3415887845CTD
OFFSIDES
US FAERS
2Drug ineffectiveFAERS: 26US FAERS
3HypotensionFAERS: 18US FAERS
4Blood pressure inadequately controlledFAERS: 17OFFSIDES
US FAERS
5FatigueFAERS: 1615887845CTD
OFFSIDES
US FAERS
6HeadacheFAERS: 15US FAERS
7Cerebrovascular accidentFAERS: 12US FAERS
8Chest PainFAERS: 12OFFSIDES
US FAERS
9ArthralgiaFAERS: 11US FAERS
10AstheniaFAERS: 10US FAERS
11Hypertensive crisisFAERS: 10US FAERS
12NauseaFAERS: 1015887845CTD
US FAERS
13PainFAERS: 10US FAERS
14TachycardiaFAERS: 10US FAERS
15PneumoniaFAERS: 9US FAERS
16Erectile dysfunctionFAERS: 8OFFSIDES
US FAERS
17Feeling abnormalFAERS: 8US FAERS
18Product quality issueFAERS: 8US FAERS
19Anaphylactic shockFAERS: 7US FAERS
20Back PainFAERS: 7US FAERS
21MyalgiaFAERS: 7US FAERS
22Weight decreasedFAERS: 7US FAERS
23Chest discomfortFAERS: 6US FAERS
24HypersensitivityFAERS: 6US FAERS
25Myocardial InfarctionFAERS: 6US FAERS
26SyncopeFAERS: 6US FAERS
27TinnitusFAERS: 6US FAERS
28Visual ImpairmentFAERS: 6US FAERS
29AlopeciaFAERS: 5US FAERS
30Blood urea increasedFAERS: 5US FAERS
31DehydrationFAERS: 5US FAERS
32PalpitationsFAERS: 5US FAERS
33PruritusFAERS: 5US FAERS
34VertigoFAERS: 5US FAERS
35ArthritisFAERS: 4US FAERS
36Cerebral InfarctionFAERS: 4US FAERS
37LethargyFAERS: 4US FAERS
38MalaiseFAERS: 4US FAERS
39Musculoskeletal PainFAERS: 4US FAERS
40OverdoseFAERS: 4US FAERS
41PneumothoraxFAERS: 4US FAERS
42Suicide attemptFAERS: 4US FAERS
43Unevaluable eventFAERS: 4OFFSIDES
US FAERS
44VomitingFAERS: 4US FAERS
45Abdominal discomfortFAERS: 3OFFSIDES
US FAERS
46AngioedemaFAERS: 3US FAERS
47Atrial FibrillationFAERS: 3US FAERS
48BlindnessFAERS: 3US FAERS
49Blood creatine increasedFAERS: 3US FAERS
50Blood potassium decreasedFAERS: 3OFFSIDES
US FAERS
51BronchitisFAERS: 3US FAERS
52ConstipationFAERS: 3US FAERS
53DeafnessFAERS: 3US FAERS
54Drug abuseFAERS: 3US FAERS
55Drug dispensing errorFAERS: 3OFFSIDES
US FAERS
56DyspepsiaFAERS: 3US FAERS
57EpistaxisFAERS: 3US FAERS
58Gastrointestinal PainFAERS: 3US FAERS
59Inappropriate schedule of drug administrationFAERS: 3OFFSIDES
US FAERS
60Lichen PlanusFAERS: 3OFFSIDES
US FAERS
61Lip swellingFAERS: 3US FAERS
62Medication ErrorFAERS: 3US FAERS
63NeutropeniaFAERS: 3US FAERS
64ObesityFAERS: 3US FAERS
65PresyncopeFAERS: 3US FAERS
66Product taste abnormalFAERS: 3US FAERS
67SepsisFAERS: 3US FAERS
68Skin lacerationFAERS: 3OFFSIDES
US FAERS
69Therapeutic response unexpectedFAERS: 3OFFSIDES
US FAERS
70ToothacheFAERS: 3US FAERS
71AbasiaFAERS: 2US FAERS
72Abdominal PainFAERS: 2OFFSIDES
US FAERS
73Accidental overdoseFAERS: 2US FAERS
74Activities of daily living impairedFAERS: 2OFFSIDES
US FAERS
75AgranulocytosisFAERS: 2US FAERS
76Allergy to chemicalsFAERS: 2US FAERS
77AphasiaFAERS: 2US FAERS
78AphoniaFAERS: 2OFFSIDES
US FAERS
79Atrial FlutterFAERS: 2OFFSIDES
US FAERS
80Blood aldosterone increasedFAERS: 2US FAERS
81Blood creatinine increasedFAERS: 2US FAERS
82Blood glucose increasedFAERS: 2US FAERS
83Blood pressure fluctuationFAERS: 2OFFSIDES
US FAERS
84Blood sodium increasedFAERS: 2US FAERS
85BronchospasmFAERS: 2US FAERS
86Capillary FragilityFAERS: 2US FAERS
87ChromaturiaFAERS: 2US FAERS
88Diabetes MellitusFAERS: 2US FAERS
89DisorientationFAERS: 2US FAERS
90DysgeusiaFAERS: 2US FAERS
91ErythemaFAERS: 2US FAERS
92Frustration tolerance decreasedFAERS: 2US FAERS
93GoutFAERS: 2OFFSIDES
US FAERS
94HypothyroidismFAERS: 2US FAERS
95IncontinenceFAERS: 2OFFSIDES
US FAERS
96InfluenzaFAERS: 2US FAERS
97Joint InstabilityFAERS: 2US FAERS
98Joint swellingFAERS: 2US FAERS
99Lupus-like syndromeFAERS: 2OFFSIDES
US FAERS
100Macular degenerationFAERS: 2US FAERS
101Musculoskeletal stiffnessFAERS: 2US FAERS
102NocturiaFAERS: 2OFFSIDES
US FAERS
103Packaging design issueFAERS: 2US FAERS
104Pain of skinFAERS: 2US FAERS
105PancreatitisFAERS: 2US FAERS
106PolyuriaFAERS: 2OFFSIDES
US FAERS
107Product substitution issueFAERS: 2US FAERS
108Productive CoughFAERS: 2OFFSIDES
US FAERS
109Pulmonary EmbolismFAERS: 2US FAERS
110Renin increasedFAERS: 2US FAERS
111Respiratory arrestFAERS: 2US FAERS
112Respiratory distressFAERS: 2US FAERS
113SluggishnessFAERS: 2US FAERS
114SomnolenceFAERS: 2US FAERS
115StressFAERS: 2US FAERS
116Sudden deathFAERS: 2US FAERS
117Throat irritationFAERS: 2US FAERS
118ThrombocytopeniaFAERS: 2US FAERS
119TremorFAERS: 2US FAERS
120Troponin T increasedFAERS: 2US FAERS
121Urinary IncontinenceFAERS: 2US FAERS
122Urinary tract infectionFAERS: 2US FAERS
123Accidental drug intake by childFAERS: 1US FAERS
124Accidental exposureFAERS: 1US FAERS
125AmnesiaFAERS: 1US FAERS
126Ankle FractureFAERS: 1OFFSIDES
US FAERS
127AnxietyFAERS: 1OFFSIDES
US FAERS
128Aortic Valve StenosisFAERS: 1US FAERS
129ArthropathyFAERS: 1US FAERS
130AsthmaFAERS: 1US FAERS
131Biliary ColicFAERS: 1US FAERS
132Blood amylase increasedFAERS: 1US FAERS
133Blood sodium decreasedFAERS: 1US FAERS
134Blood triglycerides increasedFAERS: 1US FAERS
135BradykinesiaFAERS: 1US FAERS
136BradyphreniaFAERS: 1US FAERS
137Breast tendernessFAERS: 1US FAERS
138Burning sensationFAERS: 1US FAERS
139CataractFAERS: 1US FAERS
140CheilitisFAERS: 1US FAERS
141ChillsFAERS: 1US FAERS
142CholelithiasisFAERS: 1US FAERS
143Coronary Artery DiseaseFAERS: 1US FAERS
144Deep Vein ThrombosisFAERS: 1US FAERS
145Depressed moodFAERS: 1US FAERS
146Diabetes InsipidusFAERS: 1US FAERS
147Disease recurrenceFAERS: 1US FAERS
148DiverticulitisFAERS: 1US FAERS
149Drug administration errorFAERS: 1US FAERS
150Dry skinFAERS: 1US FAERS
151DysphemiaFAERS: 1US FAERS
152Endometrial cancer stage IIFAERS: 1US FAERS
153EpiglottitisFAERS: 1OFFSIDES
US FAERS
154Eye painFAERS: 1US FAERS
155Feeling ColdFAERS: 1US FAERS
156Feeling of body temperature changeFAERS: 1US FAERS
157FlatulenceFAERS: 1US FAERS
158FlushingFAERS: 1US FAERS
159Food AllergyFAERS: 1US FAERS
160FrustrationFAERS: 1US FAERS
161GammopathyFAERS: 1US FAERS
162General physical health deteriorationFAERS: 1US FAERS
163HepatitisFAERS: 1US FAERS
164Hypoaesthesia facialFAERS: 1US FAERS
165HypokinesiaFAERS: 1US FAERS
166Iliac artery occlusionFAERS: 1US FAERS
167Impaired work abilityFAERS: 1US FAERS
168Incorrect drug administration durationFAERS: 1US FAERS
169InfarctionFAERS: 1US FAERS
170InfectionFAERS: 1US FAERS
171Infective tenosynovitisFAERS: 1US FAERS
172InflammationFAERS: 1US FAERS
173Intracranial AneurysmFAERS: 1US FAERS
174Joint injuryFAERS: 1US FAERS
175Labile blood pressureFAERS: 1US FAERS
176Labile hypertensionFAERS: 1US FAERS
177LacerationFAERS: 1US FAERS
178Lip and/or oral cavity cancerFAERS: 1US FAERS
179Liver AbscessFAERS: 1US FAERS
180LymphomaFAERS: 1US FAERS
181Memory impairmentFAERS: 1US FAERS
182Meniscus injuryFAERS: 1US FAERS
183MenorrhagiaFAERS: 1US FAERS
184Multiple MyelomaFAERS: 1US FAERS
185Muscle strainFAERS: 1US FAERS
186Muscle tightnessFAERS: 1US FAERS
187Musculoskeletal discomfortFAERS: 1OFFSIDES
US FAERS
188NasopharyngitisFAERS: 1US FAERS
189Neck PainFAERS: 1US FAERS
190Nerve injuryFAERS: 1US FAERS
191NervousnessFAERS: 1US FAERS
192Night sweatsFAERS: 1US FAERS
193NystagmusFAERS: 1US FAERS
194OligohydramniosFAERS: 1US FAERS
195OnychoclasisFAERS: 1US FAERS
196Oral painFAERS: 1US FAERS
197Oropharyngeal painFAERS: 1US FAERS
198Periorbital disorderFAERS: 1US FAERS
199Peripheral swellingFAERS: 1US FAERS
200PleurisyFAERS: 1US FAERS
201Poor peripheral circulationFAERS: 1US FAERS
202Postoperative infectionFAERS: 1US FAERS
203Premature EjaculationFAERS: 1US FAERS
204Product blister packaging issueFAERS: 1US FAERS
205Protein total increasedFAERS: 1US FAERS
206PsoriasisFAERS: 1US FAERS
207Pulmonary congestionFAERS: 1US FAERS
208PyelonephritisFAERS: 1US FAERS
209Rash erythematousFAERS: 1US FAERS
210Renal Artery StenosisFAERS: 1US FAERS
211Renal Cell CarcinomaFAERS: 1US FAERS
212Renal painFAERS: 1US FAERS
213RhabdomyolysisFAERS: 1US FAERS
214Single functional kidneyFAERS: 1US FAERS
215Sinus TachycardiaFAERS: 1US FAERS
216Skin reactionFAERS: 1US FAERS
217SwellingFAERS: 1US FAERS
218Tablet physical issueFAERS: 1US FAERS
219ThirstFAERS: 1US FAERS
220ThrombosisFAERS: 1US FAERS
221Troponin increasedFAERS: 1US FAERS
222Upper respiratory tract congestionFAERS: 1US FAERS
223Urinary RetentionFAERS: 1US FAERS
224UrticariaFAERS: 1US FAERS
225UvulitisFAERS: 1US FAERS
226Vascular bypass graftFAERS: 1US FAERS
227Vasculitic rashFAERS: 1US FAERS
228VitiligoFAERS: 1US FAERS
229Walking aid userFAERS: 1US FAERS
230Wheelchair userFAERS: 1US FAERS
231Wrong drug administeredFAERS: 1US FAERS
232Wrong technique in product usage processFAERS: 1US FAERS
233jaundiceFAERS: 1US FAERS
234AbuseOFFSIDES
235AcidosisOFFSIDES
236AnhedoniaOFFSIDES
237AnisocoriaOFFSIDES
238Application site vesiclesOFFSIDES
239Axillary vein thrombosisOFFSIDES
240BedriddenOFFSIDES
241Benign Prostatic HyperplasiaOFFSIDES
242Blood glucose abnormalOFFSIDES
243Blood immunoglobulin EOFFSIDES
244Blood iron increasedOFFSIDES
245Blood osmolarity decreasedOFFSIDES
246Blood sodiumOFFSIDES
247Blood uric acidOFFSIDES
248Bone painOFFSIDES
249Brain scan abnormalOFFSIDES
250ChokingOFFSIDES
251Chronic Fatigue SyndromeOFFSIDES
252Circumstance or information capable of leading to medication errorOFFSIDES
253Cleft PalateOFFSIDES
254Cogwheel RigidityOFFSIDES
255Device malfunctionOFFSIDES
256Dialysis disequilibrium syndromeOFFSIDES
257Diarrhea15887845CTD
258Diverticular perforationOFFSIDES
259Drug abuserOFFSIDES
260Drug toxicityOFFSIDES
261Drug withdrawal headacheOFFSIDES
262Economic problemOFFSIDES
263Embolic cerebral infarctionOFFSIDES
264Enamel anomalyOFFSIDES
265Exfoliative rashOFFSIDES
266Head titubationOFFSIDES
267Hepatitis C antibody positiveOFFSIDES
268Hilar lymphadenopathyOFFSIDES
269LeukoencephalopathyOFFSIDES
270Mental status changesOFFSIDES
271Metastatic bronchial carcinomaOFFSIDES
272MorpheaOFFSIDES
273Myoclonic EpilepsyOFFSIDES
274Nervous tensionOFFSIDES
275Nipple painOFFSIDES
276OrthopneaOFFSIDES
277Pancreatic enzymes increasedOFFSIDES
278Physical disabilityOFFSIDES
279Pustular psoriasisOFFSIDES
280Pyoderma GangrenosumOFFSIDES
281Rebound effectOFFSIDES
282Renal embolismOFFSIDES
283RhinitisOFFSIDES
284Ruptured cerebral aneurysmOFFSIDES
285SpondylosisOFFSIDES
286Tooth AvulsionOFFSIDES
287Troponin TOFFSIDES
288Vascular graft complicationOFFSIDES
289Viral labyrinthitisOFFSIDES
290Vitamin B 12 DeficiencyOFFSIDES
291Vulvovaginal burning sensationOFFSIDES
292effusionOFFSIDES
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