MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Butylscopolammonium Bromide

(HOZOZZFCZRXYEK-GXLSIKBRSA-M)

Structure

SMILES: CCCC[N+]1(C)[C@H]2CC(C[C@H]1[C@H]1[C@@H]2O1)OC(=O)C(c1ccccc1)CO.[Br-]
Molecular Formula:: C21H30BrNO4
Molecular Weight:: 440.371
Log P:: -0.8042
Hydrogen Bond Acceptor:: 4
Hydrogen Bond Donor:: 1
TPSA:: 59.06
CAS Number(s):: 149-64-4

Synonym(s)

Butylscopolammonium Bromide

Hyoscinbutylbromide

Scopolaminebutylbromide

Buscapine

Buscolysin

Buscopan

Butylscopolamine

Hyoscine N-Butylbromide

N-Butylscopolammonium Bromide

10.

Scopolan

11.

Bromide, Butylscopolammonium

12.

Bromide, N-Butylscopolammonium

13.

Hyoscine N Butylbromide

14.

N Butylscopolammonium Bromide

15.

N-Butylbromide, Hyoscine

External Link(s)

MeSH	D002086
PubChem Compound	9003

Adverse Drug Event(s)

	Name	Number of Reports	Data Source
1	Pain	FAERS: 1 Canada Vigilance: 1	Canada Vigilance OFFSIDES US FAERS
2	Palpitations	FAERS: 1	US FAERS
3	Unevaluable event	FAERS: 1	US FAERS
4	Abdominal Pain	Canada Vigilance: 1	Canada Vigilance OFFSIDES
5	Abdominal discomfort		OFFSIDES
6	Abnormal vision		OFFSIDES
7	Abuse		OFFSIDES
8	Acidosis		OFFSIDES
9	Acquired porphyria		OFFSIDES
10	Agraphia		OFFSIDES
11	Amnesia	Canada Vigilance: 1	Canada Vigilance
12	Anal Fissure		OFFSIDES
13	Anaphylactic shock		SIDER
14	Anaphylactoid Reaction	Canada Vigilance: 1	Canada Vigilance SIDER
15	Angioedema		SIDER
16	Appendicitis		OFFSIDES
17	Ascites		OFFSIDES
18	Asthenopia		OFFSIDES
19	Atrial tachycardia		OFFSIDES
20	Autoimmune thrombocytopenia		OFFSIDES
21	Back Pain	Canada Vigilance: 1	Canada Vigilance
22	Bacterial sepsis		OFFSIDES
23	Blepharospasm		OFFSIDES
24	Blood Glucose		OFFSIDES
25	Blood bilirubin unconjugated increased		OFFSIDES
26	Blood fibrinogen		OFFSIDES
27	Blood lactate dehydrogenase increased		OFFSIDES
28	Blood potassium		OFFSIDES
29	Blood urea increased		OFFSIDES
30	Bradycardia		OFFSIDES
31	Cardiovascular insufficiency		OFFSIDES
32	Choking sensation		OFFSIDES
33	Cholecystitis		OFFSIDES
34	Chronic ulcerative colitis		OFFSIDES
35	Cold sweat		OFFSIDES
36	Colectomy		OFFSIDES
37	Colitis		OFFSIDES
38	Congenital tricuspid valve incompetence		OFFSIDES
39	Depressed Level of Consciousness		OFFSIDES
40	Dermatitis		SIDER
41	Diabetes mellitus inadequate control		OFFSIDES
42	Diarrhea		OFFSIDES
43	Disease Progression		OFFSIDES
44	Dizziness	Canada Vigilance: 3	Canada Vigilance OFFSIDES SIDER
45	Drowsiness		OFFSIDES
46	Drug Dependence	Canada Vigilance: 1	Canada Vigilance
47	Drug exposure during pregnancy		OFFSIDES
48	Drug ineffective	Canada Vigilance: 6	Canada Vigilance
49	Dysmenorrhea		OFFSIDES
50	Dysphasia		OFFSIDES
51	Dysuria		OFFSIDES
52	Enterovesical Fistula		OFFSIDES
53	Eosinophilic myocarditis		OFFSIDES
54	Erythema Nodosum		OFFSIDES
55	Erythema		SIDER
56	Euphoric mood		OFFSIDES
57	Eye pain	Canada Vigilance: 1	Canada Vigilance
58	Fatigue	Canada Vigilance: 1	Canada Vigilance
59	Febrile Neutropenia		OFFSIDES
60	Fixed drug eruption		SIDER
61	Flushing		SIDER
62	Gamma-Glutamyltransferase Increased		OFFSIDES
63	Gastrectomy		OFFSIDES
64	Gastroenteritis		OFFSIDES
65	Gastrointestinal stoma complication		OFFSIDES
66	General physical condition		OFFSIDES
67	Glaucoma		SIDER
68	Headache	Canada Vigilance: 1	Canada Vigilance
69	Hypersensitivity		SIDER
70	Hyperventilation		OFFSIDES
71	Hypotension		SIDER
72	Impaired gastric emptying	Canada Vigilance: 1	Canada Vigilance
73	Intention tremor		OFFSIDES
74	Intestinal Obstruction	Canada Vigilance: 1	Canada Vigilance OFFSIDES
75	Joint Instability		OFFSIDES
76	Kidney Failure		OFFSIDES
77	Leukopenia neonatal		OFFSIDES
78	Malaise	Canada Vigilance: 1	Canada Vigilance
79	Malignant neoplasm progression		OFFSIDES
80	Milk Allergy		OFFSIDES
81	Multiple drug overdose		OFFSIDES
82	Multiple drug overdose intentional		OFFSIDES
83	Muscle Weakness		OFFSIDES
84	Musculoskeletal stiffness		OFFSIDES
85	Mydriasis		SIDER
86	Myelodysplasia		OFFSIDES
87	Nausea	Canada Vigilance: 2	Canada Vigilance OFFSIDES SIDER
88	Nephrolithiasis		OFFSIDES
89	Neuralgia		OFFSIDES
90	Neuroleptic Malignant Syndrome		OFFSIDES
91	Neutrophil count decreased		OFFSIDES
92	Pallor		OFFSIDES
93	Pancreatic Insufficiency		OFFSIDES
94	Peritonitis		OFFSIDES
95	Pharyngeal lesion		OFFSIDES
96	Pruritus	Canada Vigilance: 2	Canada Vigilance SIDER
97	Psoas Abscess		OFFSIDES
98	Psychiatric symptom		OFFSIDES
99	Pulmonary Hypertension		OFFSIDES
100	Pulmonary arterial hypertension		OFFSIDES
101	Rash erythematous	Canada Vigilance: 1	Canada Vigilance
102	Rectal polypectomy		OFFSIDES
103	Respiratory Failure		OFFSIDES
104	Retinal pigmentation		SIDER
105	Shock		SIDER
106	Sinusitis		OFFSIDES
107	Stress		OFFSIDES
108	Tachycardia	Canada Vigilance: 1	Canada Vigilance SIDER
109	Urinary Retention		SIDER
110	Urinoma		OFFSIDES
111	Urticaria	Canada Vigilance: 2	Canada Vigilance SIDER
112	Uterine contractions during pregnancy		OFFSIDES
113	Visual Impairment	Canada Vigilance: 1	Canada Vigilance SIDER
114	Wound Infection		OFFSIDES

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