MetaADEDB 2.0 @ LMMD
Semaxinib
(WUWDLXZGHZSWQZ-WQLSENKSSA-N)
Structure
SMILES
O=C1Nc2c(/C/1=C/c1[nH]c(cc1C)C)cccc2
Type(s)
Investigational
Molecular Formula:
C15H14N2O
Molecular Weight:
238.284
Log P:
3.2622
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
2
TPSA:
44.89
CAS Number(s):
194413-58-6; 204005-46-9
Synonym(s)
1.
Semaxinib
2.
3-(2,4-dimethylpyrrol-5-yl)methylidene-indolin-2-one
3.
SU 5416
4.
SU-5416
5.
SU5416
External Link(s)
MeSHC116890
PubChem Compound5329098
BindingDB4810
ChEBI91083
CHEMBLCHEMBL276711
DrugBankDB06436
IUPHAR/BPS Guide to PHARMACOLOGY5056
KEGGdr:D05819
Therapeutic Target DatabaseD0QY0V
D01PZD
D04ADG
ZINC12410091
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal Pain12673719CTD
SIDER
2Abdominal discomfortSIDER
3AcneSIDER
4Acute Coronary SyndromeSIDER
5Alcohol IntoleranceSIDER
6AlopeciaSIDER
7AngioedemaSIDER
8AnorexiaSIDER
9ArthralgiaSIDER
10AstheniaSIDER
11Back PainSIDER
12BlindnessSIDER
13Blood and lymphatic system disordersSIDER
14Blood lactate dehydrogenase increasedSIDER
15Bone painSIDER
16Chest PainSIDER
17ClonusSIDER
18ConstipationSIDER
19CystSIDER
20Deep Vein ThrombosisSIDER
21DehydrationSIDER
22DermatitisSIDER
23Diarrhea12673719CTD
24DiscomfortSIDER
25Disease ProgressionSIDER
26DizzinessSIDER
27Dry skinSIDER
28DysgeusiaSIDER
29DyspepsiaSIDER
30Dyspnea12649163
12673719		CTD
31Ear and labyrinth disordersSIDER
32EcchymosisSIDER
33EczemaSIDER
34Edema16736151CTD
35ErythemaSIDER
36ErythromelalgiaSIDER
37Exfoliative rashSIDER
38Fatigue12649163
12673719		CTD
SIDER
39Feeling abnormalSIDER
40Feeling jitterySIDER
41Fetal Diseases17993583CTD
42FlushingSIDER
43GastroenteritisSIDER
44Gastrointestinal PainSIDER
45GoutSIDER
46Headache12649163
12673719
16736151		CTD
SIDER
47HypersensitivitySIDER
48HypogeusiaSIDER
49HypotensionSIDER
50InfectionSIDER
51InfestationSIDER
52InfluenzaSIDER
53Injection Site ReactionSIDER
54LeukocytosisSIDER
55Lung diseases17993583CTD
56MYELODYSPLASTIC SYNDROMESIDER
57MalaiseSIDER
58MalnutritionSIDER
59Muscle tightnessSIDER
60Musculoskeletal PainSIDER
61Musculoskeletal discomfortSIDER
62MyalgiaSIDER
63MyelofibrosisSIDER
64Myeloid MetaplasiaSIDER
65Myocardial InfarctionSIDER
66NasopharyngitisSIDER
67NauseaSIDER
68Neoplasms17264769CTD
69NervousnessSIDER
70Optic NeuritisSIDER
71PainSIDER
72PalpitationsSIDER
73PancytopeniaSIDER
74Peripheral embolismSIDER
75PhlebitisSIDER
76PlasmacytomaSIDER
77Platelet count abnormalSIDER
78Portal Vein ThrombosisSIDER
79Protein urine presentSIDER
80PrurigoSIDER
81PruritusSIDER
82Pulmonary EmbolismSIDER
83PurpuraSIDER
84Shoulder PainSIDER
85Skin noduleSIDER
86SplenomegalySIDER
87StomatitisSIDER
88TachycardiaSIDER
89ThrombocytopeniaSIDER
90ThrombocytosisSIDER
91Thrombosis12649163CTD
SIDER
92Upset stomachSIDER
93UrticariaSIDER
94Vascular purpuraSIDER
95Venous Thrombosis16736151CTD
96VertigoSIDER
97Visual ImpairmentSIDER
98Visual disturbanceSIDER
99VomitingSIDER
100Weight decreasedSIDER
101melanoma16736151CTD
102nervous system disorderSIDER
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.