MetaADEDB 2.0 @ LMMD
benzonatate
(MAFMQEKGGFWBAB-UHFFFAOYSA-N)
Structure
SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOCCOC(=O)c1ccc(cc1)NCCCC
Type(s)
Approved
ATC code(s)
R05DB01
Molecular Formula:
C30H53NO11
Molecular Weight:
603.742
Log P:
2.9076
Hydrogen Bond Acceptor:
12
Hydrogen Bond Donor:
1
TPSA:
121.4
CAS Number(s):
104-31-4
Synonym(s)
1.
benzonatate
2.
Tessalon
External Link(s)
MeSHC029755
PubChem Compound7699
ChEBI3032
CHEMBLCHEMBL1374379
DrugBankDB00868
IUPHAR/BPS Guide to PHARMACOLOGY7611
KEGGdr:D00242
Therapeutic Target DatabaseD0Q2ES
ZINC3830276
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 24US FAERS
2Cardiac ArrestFAERS: 21US FAERS
3OverdoseFAERS: 19US FAERS
4DizzinessFAERS: 14OFFSIDES
SIDER
US FAERS
5NauseaFAERS: 11OFFSIDES
SIDER
US FAERS
6Ventricular FibrillationFAERS: 11OFFSIDES
US FAERS
7Respiratory arrestFAERS: 9US FAERS
8Feeling abnormalFAERS: 8SIDER
US FAERS
9HeadacheFAERS: 8SIDER
US FAERS
10SomnolenceFAERS: 6US FAERS
11UrticariaFAERS: 6US FAERS
12VomitingFAERS: 6US FAERS
13Accidental overdoseFAERS: 5US FAERS
14Chest PainFAERS: 5OFFSIDES
US FAERS
15Chest discomfortFAERS: 5US FAERS
16Toxicity to various agentsFAERS: 5US FAERS
17Unresponsive to stimuliFAERS: 5OFFSIDES
US FAERS
18Accidental drug intake by childFAERS: 4US FAERS
19BronchospasmFAERS: 4SIDER
US FAERS
20Completed SuicideFAERS: 4US FAERS
21HypersensitivityFAERS: 4SIDER
US FAERS
22HypotensionFAERS: 4US FAERS
23Medication ErrorFAERS: 4US FAERS
24Metabolic acidosisFAERS: 4US FAERS
25PruritusFAERS: 4SIDER
US FAERS
26TremorFAERS: 4SIDER
US FAERS
27AphoniaFAERS: 3US FAERS
28BlindnessFAERS: 3US FAERS
29BradycardiaFAERS: 3OFFSIDES
US FAERS
30ChokingFAERS: 3US FAERS
31ConstipationFAERS: 3SIDER
US FAERS
32Drug dose omissionFAERS: 3US FAERS
33Dry skinFAERS: 3US FAERS
34DysphoniaFAERS: 3US FAERS
35PneumoniaFAERS: 3US FAERS
36Unevaluable eventFAERS: 3OFFSIDES
US FAERS
37Visual ImpairmentFAERS: 3US FAERS
38AcidosisFAERS: 2US FAERS
39ArthralgiaFAERS: 2US FAERS
40Atrial tachycardiaFAERS: 2OFFSIDES
US FAERS
41Blood glucose increasedFAERS: 2US FAERS
42BronchitisFAERS: 2OFFSIDES
US FAERS
43Choking sensationFAERS: 2OFFSIDES
US FAERS
44ConfabulationFAERS: 2OFFSIDES
US FAERS
45CyanosisFAERS: 2US FAERS
46DisorientationFAERS: 2US FAERS
47Drug administration errorFAERS: 2US FAERS
48DysuriaFAERS: 2US FAERS
49Incorrect dose administeredFAERS: 2US FAERS
50Intentional product misuseFAERS: 2US FAERS
51LethargyFAERS: 2US FAERS
52MalaiseFAERS: 2US FAERS
53No adverse eventFAERS: 2US FAERS
54PalpitationsFAERS: 2US FAERS
55Pharmaceutical product complaintFAERS: 2US FAERS
56PneumothoraxFAERS: 2OFFSIDES
US FAERS
57Pre-existing condition improvedFAERS: 2US FAERS
58PresyncopeFAERS: 2US FAERS
59Product physical issueFAERS: 2US FAERS
60Product substitution issueFAERS: 2US FAERS
61Rash erythematousFAERS: 2US FAERS
62SwellingFAERS: 2US FAERS
63TachycardiaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
64Therapeutic response unexpectedFAERS: 2US FAERS
65WheezingFAERS: 2US FAERS
66AbasiaFAERS: 1US FAERS
67Abdominal PainFAERS: 1OFFSIDES
US FAERS
68Abdominal discomfortFAERS: 1OFFSIDES
SIDER
US FAERS
69Accidental exposure to productFAERS: 1US FAERS
70Accidental exposureFAERS: 1US FAERS
71AgitationFAERS: 1SIDER
US FAERS
72Alcohol IntoleranceFAERS: 1US FAERS
73AmnesiaFAERS: 1US FAERS
74Anaphylactic shockFAERS: 1US FAERS
75AneurysmFAERS: 1US FAERS
76AngerFAERS: 1US FAERS
77AngioedemaFAERS: 1US FAERS
78Animal biteFAERS: 1US FAERS
79Anoxic EncephalopathyFAERS: 1OFFSIDES
US FAERS
80AnxietyFAERS: 1OFFSIDES
US FAERS
81ArthropathyFAERS: 1OFFSIDES
US FAERS
82AstheniaFAERS: 1OFFSIDES
US FAERS
83AsthmaFAERS: 1OFFSIDES
US FAERS
84Atrial FibrillationFAERS: 1US FAERS
85Blood pressure inadequately controlledFAERS: 1US FAERS
86Brain DeathFAERS: 1US FAERS
87Burning sensationFAERS: 1US FAERS
88ChillsFAERS: 1US FAERS
89Cold sweatFAERS: 1US FAERS
90Coma scale abnormalFAERS: 1US FAERS
91Depressed Level of ConsciousnessFAERS: 1SIDER
US FAERS
92Diabetes MellitusFAERS: 1US FAERS
93DisabilityFAERS: 1US FAERS
94DiscomfortFAERS: 1US FAERS
95Disseminated Intravascular CoagulationFAERS: 1US FAERS
96DissociationFAERS: 1US FAERS
97Documented hypersensitivity to administered drugFAERS: 1US FAERS
98Drug dispensing errorFAERS: 1US FAERS
99Drug effect delayedFAERS: 1US FAERS
100Drug effect incompleteFAERS: 1US FAERS
101Drug prescribing errorFAERS: 1US FAERS
102DysgeusiaFAERS: 1US FAERS
103Economic problemFAERS: 1OFFSIDES
US FAERS
104EructationFAERS: 1US FAERS
105Expired drug administeredFAERS: 1OFFSIDES
US FAERS
106Facial PainFAERS: 1US FAERS
107Feeling ColdFAERS: 1US FAERS
108HyperventilationFAERS: 1US FAERS
109Incorrect route of drug administrationFAERS: 1US FAERS
110InfluenzaFAERS: 1US FAERS
111Intentional drug misuseFAERS: 1OFFSIDES
US FAERS
112Joint stiffnessFAERS: 1US FAERS
113Joint swellingFAERS: 1US FAERS
114LaryngitisFAERS: 1US FAERS
115LaryngospasmFAERS: 1SIDER
US FAERS
116Lip swellingFAERS: 1US FAERS
117Memory impairmentFAERS: 1US FAERS
118Mood swingsFAERS: 1US FAERS
119Musculoskeletal chest painFAERS: 1US FAERS
120MyalgiaFAERS: 1US FAERS
121MydriasisFAERS: 1US FAERS
122Myocardial InfarctionFAERS: 1US FAERS
123Nasal discomfortFAERS: 1OFFSIDES
US FAERS
124NasopharyngitisFAERS: 1US FAERS
125Oropharyngeal painFAERS: 1OFFSIDES
US FAERS
126ParanoiaFAERS: 1US FAERS
127PhotophobiaFAERS: 1US FAERS
128Product contaminationFAERS: 1US FAERS
129Product taste abnormalFAERS: 1US FAERS
130RegurgitationFAERS: 1US FAERS
131Respiratory distressFAERS: 1US FAERS
132Restless Legs SyndromeFAERS: 1US FAERS
133Skin reactionFAERS: 1US FAERS
134SneezingFAERS: 1US FAERS
135SomnambulismFAERS: 1US FAERS
136Suicide attemptFAERS: 1US FAERS
137SynovitisFAERS: 1US FAERS
138TachyarrhythmiaFAERS: 1US FAERS
139Therapeutic product effect delayedFAERS: 1US FAERS
140TinnitusFAERS: 1OFFSIDES
US FAERS
141ToothacheFAERS: 1US FAERS
142Transcription medication errorFAERS: 1US FAERS
143Wrong technique in product usage processFAERS: 1US FAERS
144Acid refluxOFFSIDES
145Acute myocardial infarctionOFFSIDES
146Adenomatous Polyposis ColiOFFSIDES
147Adrenal massOFFSIDES
148AnhedoniaOFFSIDES
149Animal scratchOFFSIDES
150AnorexiaOFFSIDES
151AnosmiaOFFSIDES
152Aortic occlusionOFFSIDES
153Apallic syndromeOFFSIDES
154Application site vesiclesOFFSIDES
155ArteriosclerosisOFFSIDES
156ArthritisOFFSIDES
157AtelectasisOFFSIDES
158Atrial FlutterOFFSIDES
159Bile Duct StenosisOFFSIDES
160Blood GlucoseOFFSIDES
161Blood albumin decreasedOFFSIDES
162Blood alkaline phosphatase increasedOFFSIDES
163Blood cholesterolOFFSIDES
164Blood creatine decreasedOFFSIDES
165Blood creatine phosphokinase increasedOFFSIDES
166Blood creatinine increasedOFFSIDES
167Blood triglycerides increasedOFFSIDES
168Blood uric acidOFFSIDES
169Bone density decreasedOFFSIDES
170Bone fragmentationOFFSIDES
171Bone painOFFSIDES
172Bone swellingOFFSIDES
173BruxismOFFSIDES
174Buccal mucosal rougheningOFFSIDES
175Carcinoembryonic antigen increasedOFFSIDES
176Cardiac FlutterOFFSIDES
177CellulitisOFFSIDES
178Ceruloplasmin decreasedOFFSIDES
179CholangiolitisOFFSIDES
180CholecystitisOFFSIDES
181ChromaturiaOFFSIDES
182Clostridium colitisOFFSIDES
183Conjunctival abrasionOFFSIDES
184Contact DermatitisOFFSIDES
185CystoceleOFFSIDES
186DehydrationOFFSIDES
187DemyelinationOFFSIDES
188Dental cariesOFFSIDES
189Device breakageOFFSIDES
190DiabetesOFFSIDES
191Diabetes mellitus inadequate controlOFFSIDES
192Diabetic NephropathyOFFSIDES
193Diabetic RetinopathyOFFSIDES
194DiarrheaOFFSIDES
195DiplopiaOFFSIDES
196Disease ProgressionOFFSIDES
197DiverticulitisOFFSIDES
198Drug toxicityOFFSIDES
199Drug withdrawal headacheOFFSIDES
200DyspepsiaOFFSIDES
201Dysthymic DisorderOFFSIDES
202DystoniaOFFSIDES
203Ejection Fraction DecreasedOFFSIDES
204Emotional distressOFFSIDES
205Endodontic procedureOFFSIDES
206Erosive gastritisOFFSIDES
207ExcoriationOFFSIDES
208FatigueOFFSIDES
209Fatty LiverOFFSIDES
210Febrile NeutropeniaOFFSIDES
211Femoral artery occlusionOFFSIDES
212FibromyalgiaOFFSIDES
213Flank PainOFFSIDES
214Fluid overloadOFFSIDES
215FormicationOFFSIDES
216GamblingOFFSIDES
217GangreneOFFSIDES
218General physical health deteriorationOFFSIDES
219General symptomOFFSIDES
220GoiterOFFSIDES
221GoutOFFSIDES
222GranulomaOFFSIDES
223Heparin-induced thrombocytopeniaOFFSIDES
224Hepatic congestionOFFSIDES
225Hepatitis COFFSIDES
226HepatitisOFFSIDES
227HydronephrosisOFFSIDES
228HypophagiaOFFSIDES
229Impaired gastric emptyingOFFSIDES
230ImpetigoOFFSIDES
231IncontinenceOFFSIDES
232InfectionOFFSIDES
233Joint injuryOFFSIDES
234Joint sprainOFFSIDES
235Keratitis siccaOFFSIDES
236Kidney FailureOFFSIDES
237LeukoencephalopathyOFFSIDES
238Leukopenia neonatalOFFSIDES
239Life expectancy shortenedOFFSIDES
240Limb injuryOFFSIDES
241LymphedemaOFFSIDES
242Lymphocyte count decreasedOFFSIDES
243Malignant neoplasm progressionOFFSIDES
244Metastatic NeoplasmOFFSIDES
245Metastatic Renal Cell CarcinomaOFFSIDES
246Multi-organ disorderOFFSIDES
247Multiple MyelomaOFFSIDES
248Muscle necrosisOFFSIDES
249Muscle strainOFFSIDES
250Musculoskeletal discomfortOFFSIDES
251MyelitisOFFSIDES
252NephrolithiasisOFFSIDES
253NocturiaOFFSIDES
254Non-cardiac chest painOFFSIDES
255NumbnessSIDER
256Occult blood positiveOFFSIDES
257OliguriaOFFSIDES
258Oral infectionOFFSIDES
259Oral mucosal erythemaOFFSIDES
260OrchitisOFFSIDES
261OsteoporosisOFFSIDES
262OsteosclerosisOFFSIDES
263OverweightOFFSIDES
264PCO2 decreasedOFFSIDES
265Pain7784102CTD
OFFSIDES
266Pelvic abscessOFFSIDES
267Pericardial effusionOFFSIDES
268Peripheral embolismOFFSIDES
269PhonophobiaOFFSIDES
270Postoperative wound complicationOFFSIDES
271PresbyopiaOFFSIDES
272Productive CoughOFFSIDES
273Pulmonary HypertensionOFFSIDES
274Pulmonary congestionOFFSIDES
275Pulmonary vascular disorderOFFSIDES
276Refusal of treatment by relativeOFFSIDES
277Renal Artery StenosisOFFSIDES
278Renal cystOFFSIDES
279Renal lipomatosisOFFSIDES
280Respiratory FailureOFFSIDES
281Restrictive pulmonary diseaseOFFSIDES
282RhonchiOFFSIDES
283SarcoidosisOFFSIDES
284Schizoaffective DisorderOFFSIDES
285Secretion dischargeOFFSIDES
286ShockSIDER
287Sinus headacheOFFSIDES
288SinusitisOFFSIDES
289Skin lacerationOFFSIDES
290SpondylitisOFFSIDES
291Supraventricular tachycardiaOFFSIDES
292Synovial CystOFFSIDES
293TendinitisOFFSIDES
294Terminal dribblingOFFSIDES
295Tooth ExtractionOFFSIDES
296Tooth InfectionOFFSIDES
297TracheobronchitisOFFSIDES
298Transaminases increasedOFFSIDES
299Uterine CancerOFFSIDES
300Vaginal ProlapseOFFSIDES
301Venoocclusive diseaseOFFSIDES
302Visual midline shift syndromeOFFSIDES
303furuncleOFFSIDES
304treatment failureOFFSIDES
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