MetaADEDB 2.0 @ LMMD
Granisetron
(MFWNKCLOYSRHCJ-AGUYFDCRSA-N)
Structure
SMILES
CN1[C@@H]2CCC[C@H]1CC(C2)NC(=O)c1nn(c2c1cccc2)C
Type(s)
Approved; Investigational
ATC code(s)
A04AA02
Molecular Formula:
C18H24N4O
Molecular Weight:
312.409
Log P:
2.6472
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
1
TPSA:
50.16
CAS Number(s):
109889-09-0; 124998-65-8
Synonym(s)
1.
Granisetron
2.
1-Methyl-N-(endo-9-Methyl-9-Azabicyclo(3.3.1)non-3-yl)-1H-Indazole-3-Carboxamide
3.
BRL-43694
4.
BRL-43694A
5.
Granisetron Hydrochloride
6.
Granisetron Monohydrochloride
7.
Kytril
8.
BRL 43694
9.
BRL 43694A
10.
BRL43694
11.
BRL43694A
12.
Hydrochloride, Granisetron
13.
Monohydrochloride, Granisetron
External Link(s)
MeSHD017829
PubChem Compound5284566
BindingDB50449636
50291698
50363282
50443668
ChEBI5537
94501
CHEMBLCHEMBL399538
CHEMBL1290003
DrugBankDB00889
DrugCentral1329
IUPHAR/BPS Guide to PHARMACOLOGY2300
KEGGcpd:C07023
dr:D04370
Therapeutic Target DatabaseD0J5KF
ZINC100018854
100018852
347
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Product adhesion issueFAERS: 196US FAERS
2No adverse eventFAERS: 86US FAERS
3Inappropriate schedule of drug administrationFAERS: 83US FAERS
4Wrong technique in product usage processFAERS: 79US FAERS
5NauseaFAERS: 71

View details

7931490
8032707
9660534
14634790
17530482
19627023
 		CTD
OFFSIDES
SIDER
US FAERS
6Drug ineffectiveFAERS: 46US FAERS
7Drug prescribing errorFAERS: 43US FAERS
8Drug administered at inappropriate siteFAERS: 38US FAERS
9VomitingFAERS: 29

View details

1659980
7828269
7931490
7993831
8032704
8032707
8381293
9010987
9660533
9660534
12562658
14634790
15151959
15811204
16319109
17530482
18158814
19627023
21075553
 		CTD
SIDER
US FAERS
10Product use in unapproved indicationFAERS: 24US FAERS
11MalaiseFAERS: 23SIDER
US FAERS
12Product quality issueFAERS: 23US FAERS
13Product use issueFAERS: 22US FAERS
14Inappropriate schedule of product administrationFAERS: 20US FAERS
15Application site erythemaFAERS: 19SIDER
US FAERS
16Intentional product misuseFAERS: 18US FAERS
17Application site rashFAERS: 16SIDER
US FAERS
18Application site pruritusFAERS: 15SIDER
US FAERS
19Application site irritationFAERS: 11SIDER
US FAERS
20DizzinessFAERS: 1115151959
17530482		CTD
SIDER
US FAERS
21Feeling abnormalFAERS: 10SIDER
US FAERS
22HeadacheFAERS: 10

View details

7931490
7993831
8032704
8032707
8381293
9010987
9660533
9660534
10084258
15151959
17530482
 		CTD
SIDER
US FAERS
23Drug administration errorFAERS: 8US FAERS
24ErythemaFAERS: 7OFFSIDES
US FAERS
25PruritusFAERS: 7SIDER
US FAERS
26Skin irritationFAERS: 7US FAERS
27DehydrationFAERS: 6OFFSIDES
US FAERS
28HypersensitivityFAERS: 6SIDER
US FAERS
29Product administered at inappropriate siteFAERS: 6US FAERS
30Application site reactionFAERS: 5US FAERS
31ConstipationFAERS: 5

View details

7993831
8032707
8381293
9660533
9660534
10084258
20350559
 		CTD
SIDER
US FAERS
32Drug effect incompleteFAERS: 5US FAERS
33Incorrect drug administration durationFAERS: 5US FAERS
34Application site painFAERS: 4SIDER
US FAERS
35Drug ineffective for unapproved indicationFAERS: 4US FAERS
36SomnolenceFAERS: 4SIDER
US FAERS
37UrticariaFAERS: 4SIDER
US FAERS
38Application site warmthFAERS: 3US FAERS
39FatigueFAERS: 3OFFSIDES
US FAERS
40Injury associated with deviceFAERS: 3US FAERS
41LeukopeniaFAERS: 3SIDER
US FAERS
42PneumoniaFAERS: 3US FAERS
43Weight decreasedFAERS: 3US FAERS
44White blood cell count decreasedFAERS: 3US FAERS
45Wrong technique in drug usage processFAERS: 3US FAERS
46Abdominal PainFAERS: 29660534CTD
OFFSIDES
SIDER
US FAERS
47Accidental exposure to productFAERS: 2US FAERS
48Administration site rashFAERS: 2US FAERS
49AkathisiaFAERS: 2US FAERS
50AnxietyFAERS: 2OFFSIDES
SIDER
US FAERS
51Application site burnFAERS: 2US FAERS
52Application site drynessFAERS: 2US FAERS
53Application site noduleFAERS: 2US FAERS
54Application site vesiclesFAERS: 2US FAERS
55DermatitisFAERS: 2SIDER
US FAERS
56Drug administered to patient of inappropriate ageFAERS: 2US FAERS
57Dry skinFAERS: 2US FAERS
58DysuriaFAERS: 2OFFSIDES
SIDER
US FAERS
59Feeling jitteryFAERS: 2US FAERS
60Injection site erythemaFAERS: 2US FAERS
61Injection site painFAERS: 2US FAERS
62Intentional product use issueFAERS: 2US FAERS
63Medication ErrorFAERS: 2US FAERS
64Memory impairmentFAERS: 2US FAERS
65MetastasisFAERS: 2US FAERS
66Needle issueFAERS: 2US FAERS
67Night sweatsFAERS: 2US FAERS
68Occupational exposure to productFAERS: 2US FAERS
69PainFAERS: 219627023CTD
OFFSIDES
SIDER
US FAERS
70Product prescribing errorFAERS: 2US FAERS
71Pulmonary EmbolismFAERS: 2US FAERS
72RetchingFAERS: 2SIDER
US FAERS
73ThrombosisFAERS: 2US FAERS
74VertigoFAERS: 2SIDER
US FAERS
75Abdominal discomfortFAERS: 1OFFSIDES
US FAERS
76Accidental exposure to product by childFAERS: 1US FAERS
77Administration site papuleFAERS: 1US FAERS
78AgeusiaFAERS: 1US FAERS
79AgitationFAERS: 1SIDER
US FAERS
80Application site acneFAERS: 1US FAERS
81Application site swellingFAERS: 1US FAERS
82Application site urticariaFAERS: 1US FAERS
83Blister ruptureFAERS: 1US FAERS
84Blood count abnormalFAERS: 1US FAERS
85Blood creatinine decreasedFAERS: 1US FAERS
86BronchitisFAERS: 1OFFSIDES
US FAERS
87Burning sensationFAERS: 1US FAERS
88Cerebral disorderFAERS: 1US FAERS
89Chest PainFAERS: 1SIDER
US FAERS
90Chest discomfortFAERS: 1US FAERS
91ChillsFAERS: 1SIDER
US FAERS
92ColitisFAERS: 1OFFSIDES
US FAERS
93Coronary Artery DiseaseFAERS: 1US FAERS
94CyanosisFAERS: 1US FAERS
95CystitisFAERS: 1US FAERS
96DementiaFAERS: 1US FAERS
97Dermal absorption impairedFAERS: 1US FAERS
98Device difficult to useFAERS: 1US FAERS
99Device leakageFAERS: 1US FAERS
100Device use errorFAERS: 1US FAERS
101DiscomfortFAERS: 1SIDER
US FAERS
102Disease ProgressionFAERS: 1OFFSIDES
US FAERS
103DysarthriaFAERS: 1US FAERS
104DysgeusiaFAERS: 1SIDER
US FAERS
105Emotional distressFAERS: 1OFFSIDES
US FAERS
106Expired product administeredFAERS: 1US FAERS
107Febrile NeutropeniaFAERS: 1OFFSIDES
US FAERS
108Feeling ColdFAERS: 1US FAERS
109FlushingFAERS: 18032707CTD
SIDER
US FAERS
110Full blood count decreasedFAERS: 1US FAERS
111HypotensionFAERS: 1SIDER
US FAERS
112IleusFAERS: 1SIDER
US FAERS
113Incorrect dose administeredFAERS: 1US FAERS
114Incorrect product administration durationFAERS: 1US FAERS
115Incorrect route of drug administrationFAERS: 1US FAERS
116InfectionFAERS: 1OFFSIDES
SIDER
US FAERS
117Infusion site infectionFAERS: 1US FAERS
118Injection site abscessFAERS: 1US FAERS
119Injection site cellulitisFAERS: 1US FAERS
120Injection site exfoliationFAERS: 1US FAERS
121Intercepted drug prescribing errorFAERS: 1US FAERS
122Intercepted medication errorFAERS: 1US FAERS
123Intercepted product prescribing errorFAERS: 1US FAERS
124Intra-abdominal fluid collectionFAERS: 1US FAERS
125LacerationFAERS: 1US FAERS
126Maternal exposure during breast feedingFAERS: 1US FAERS
127Medication residue presentFAERS: 1US FAERS
128MegacolonFAERS: 1US FAERS
129Muscle SpasticityFAERS: 1US FAERS
130Musculoskeletal PainFAERS: 1US FAERS
131Myocardial InfarctionFAERS: 1US FAERS
132NasopharyngitisFAERS: 1US FAERS
133NervousnessFAERS: 1SIDER
US FAERS
134NeutropeniaFAERS: 1US FAERS
135Neutrophil count decreasedFAERS: 1OFFSIDES
US FAERS
136NoduleFAERS: 1OFFSIDES
US FAERS
137ObstructionFAERS: 1US FAERS
138PalpitationsFAERS: 1SIDER
US FAERS
139Physical product label issueFAERS: 1US FAERS
140PresyncopeFAERS: 1US FAERS
141Procedural complicationFAERS: 1US FAERS
142Product administered to patient of inappropriate ageFAERS: 1US FAERS
143Product dosage form issueFAERS: 1US FAERS
144Product dose omissionFAERS: 1US FAERS
145Product formulation issueFAERS: 1US FAERS
146Product label confusionFAERS: 1US FAERS
147Product outer packaging issueFAERS: 1US FAERS
148Product packaging issueFAERS: 1US FAERS
149Product physical issueFAERS: 1US FAERS
150Product storage errorFAERS: 1US FAERS
151Psychiatric symptomFAERS: 1US FAERS
152Respiratory FailureFAERS: 1US FAERS
153Respiratory tract congestionFAERS: 1OFFSIDES
US FAERS
154RestlessnessFAERS: 1US FAERS
155Serotonin SyndromeFAERS: 1US FAERS
156Skin discomfortFAERS: 1US FAERS
157SyncopeFAERS: 1SIDER
US FAERS
158Therapeutic product ineffectiveFAERS: 1US FAERS
159Therapy cessationFAERS: 1US FAERS
160Therapy non-responderFAERS: 1US FAERS
161ThirstFAERS: 1US FAERS
162ThrombocytopeniaFAERS: 1SIDER
US FAERS
163Urinary RetentionFAERS: 1US FAERS
164Venous thrombosis limbFAERS: 1OFFSIDES
US FAERS
165Abdominal massOFFSIDES
166Abdominal rigidityOFFSIDES
167Abnormal visionSIDER
168Acid refluxOFFSIDES
169ActinomycosisOFFSIDES
170Acute graft versus host disease in liverOFFSIDES
171Alanine Aminotransferase IncreasedOFFSIDES
SIDER
172Albumin globulin ratio decreasedOFFSIDES
173AlopeciaOFFSIDES
SIDER
174AlveolitisOFFSIDES
175Analgesic drug level above therapeuticOFFSIDES
176Anaphylactic shockSIDER
177Anastomotic ulcerOFFSIDES
178Angina PectorisSIDER
179AnhedoniaOFFSIDES
180Anorexia30336258CTD
OFFSIDES
181Antithrombin III decreasedOFFSIDES
182ArteriosclerosisOFFSIDES
183ArthralgiaSIDER
184Aspartate Aminotransferase IncreasedSIDER
185Aspiration PneumoniaOFFSIDES
186AstheniaOFFSIDES
SIDER
187AtaxiaOFFSIDES
188AtelectasisOFFSIDES
189Atrial FibrillationSIDER
190Atrial tachycardiaOFFSIDES
191Atrioventricular BlockSIDER
192Blood GlucoseOFFSIDES
193Blood chloride decreasedOFFSIDES
194Blood cholesterolOFFSIDES
195Blood fibrinogenOFFSIDES
196Blood lactate dehydrogenase increasedOFFSIDES
197Blood magnesium decreasedOFFSIDES
198Blood potassium increasedOFFSIDES
199Blood sodium abnormalOFFSIDES
200Blood sodiumOFFSIDES
201Blood urea abnormalOFFSIDES
202Blood uric acidOFFSIDES
203Bradycardia7828269CTD
SIDER
204Bronchial ObstructionOFFSIDES
205Bulbar palsyOFFSIDES
206Cardiac TamponadeOFFSIDES
207Catheter placementOFFSIDES
208Catheter related complicationOFFSIDES
209Catheter related infectionOFFSIDES
210CellulitisOFFSIDES
211Cervicobrachial syndromeOFFSIDES
212Chemotherapeutic drug level increasedOFFSIDES
213Choking sensationOFFSIDES
214Clostridium difficile colitisOFFSIDES
215Cold sweatOFFSIDES
216Completed SuicideOFFSIDES
217Concomitant disease progressionOFFSIDES
218Congenital heart diseaseOFFSIDES
219Coronary angioplastyOFFSIDES
220CraniotomyOFFSIDES
221Cytomegalovirus test positiveOFFSIDES
222DebridementOFFSIDES
223DemyelinationOFFSIDES
224Dental FistulaOFFSIDES
225Dental abscessOFFSIDES
226Dental cariesOFFSIDES
227Depressed Level of ConsciousnessOFFSIDES
228Diarrhea10084258
17530482		CTD
OFFSIDES
229Disseminated Intravascular CoagulationOFFSIDES
230DiverticulitisOFFSIDES
231Drug toxicityOFFSIDES
232Duodenal UlcerOFFSIDES
233DyspepsiaSIDER
234Ear and labyrinth disordersSIDER
235Electrocardiogram poor R-wave progressionOFFSIDES
236Embolism infectiveOFFSIDES
237Enlargement abdomenSIDER
238EnterocolitisOFFSIDES
239EosinophiliaSIDER
240EpistaxisSIDER
241Epstein-Barr virus associated lymphoproliferative disorderOFFSIDES
242Erectile dysfunctionOFFSIDES
243Fat necrosisOFFSIDES
244Febrile infectionOFFSIDES
245FibromyalgiaOFFSIDES
246FlatulenceSIDER
247Gamma-Glutamyltransferase IncreasedOFFSIDES
SIDER
248Gastrointestinal PainSIDER
249Gastrointestinal motility disorderOFFSIDES
250General physical health deteriorationOFFSIDES
251Gingival erythemaOFFSIDES
252Granulocyte count decreasedOFFSIDES
253GranulocytosisOFFSIDES
254HiccoughOFFSIDES
255Hip surgeryOFFSIDES
256Histiocytosis haematophagicOFFSIDES
257HyperkeratosisOFFSIDES
258Hypertensive heart diseaseOFFSIDES
259HysterectomyOFFSIDES
260Immunodeficiency congenitalOFFSIDES
261IncontinenceOFFSIDES
262Increased bronchial secretionSIDER
263Instillation site painSIDER
264Intervertebral Disc DegenerationOFFSIDES
265Intestinal ObstructionOFFSIDES
266Intestinal infarctionOFFSIDES
267Joint injuryOFFSIDES
268Klebsiella sepsisOFFSIDES
269Left Ventricular HypertrophyOFFSIDES
270Left atrial dilatationOFFSIDES
271LeukocytosisSIDER
272LeukodystrophyOFFSIDES
273Leukopenia neonatalOFFSIDES
274Liver transplant rejectionOFFSIDES
275Loose toothOFFSIDES
276Lymph node palpableOFFSIDES
277LymphedemaOFFSIDES
278Lymphocyte count decreasedOFFSIDES
279Malignant neoplasm progressionOFFSIDES
280MalnutritionSIDER
281Maxillofacial operationOFFSIDES
282Mental status changesOFFSIDES
283MetaplasiaOFFSIDES
284Muscle WeaknessOFFSIDES
285Musculoskeletal chest painOFFSIDES
286Musculoskeletal discomfortSIDER
287MyelitisOFFSIDES
288MyelodysplasiaOFFSIDES
289NephrolithiasisOFFSIDES
290Neutropenic sepsisOFFSIDES
291Nutritional condition abnormalOFFSIDES
292OliguriaOFFSIDES
SIDER
293Oral Cavity FistulaOFFSIDES
294Oropharyngeal painOFFSIDES
295OsteomyelitisOFFSIDES
296OsteopeniaOFFSIDES
297OsteoporosisOFFSIDES
298PallorOFFSIDES
299Pancreatic CystOFFSIDES
300PancreatitisOFFSIDES
301ParaparesisOFFSIDES
302Pericardial effusionOFFSIDES
303PericarditisOFFSIDES
304Perivascular dermatitisOFFSIDES
305Pilonidal CystOFFSIDES
306Platelet TransfusionOFFSIDES
307PleurisyOFFSIDES
308PneumothoraxOFFSIDES
309Primary sequestrumOFFSIDES
310Productive CoughOFFSIDES
311Prostate cancer recurrentOFFSIDES
312Protein total decreasedOFFSIDES
313Puncture site painSIDER
314Purulent dischargeOFFSIDES
315PyelonephritisOFFSIDES
316Pyogenic granulomaOFFSIDES
317RhinitisSIDER
318Risus sardonicusOFFSIDES
319SarcoidosisOFFSIDES
320SequestrectomyOFFSIDES
321ShockSIDER
322Shunt malfunctionOFFSIDES
323Sigmoid Neoplasms15494386CTD
324Sinus bradycardiaSIDER
325SinusitisOFFSIDES
SIDER
326Spinal column stenosisOFFSIDES
327SweatingSIDER
328TachycardiaSIDER
329Taste DisordersSIDER
330TensionSIDER
331TetanyOFFSIDES
332ThoracotomyOFFSIDES
333ThyroiditisOFFSIDES
334TonsillitisOFFSIDES
335Tooth ExtractionOFFSIDES
336Tooth InfectionOFFSIDES
337Toxicologic test abnormalOFFSIDES
338TremorSIDER
339Umbilical herniaOFFSIDES
340Unresponsive to stimuliOFFSIDES
341Urinary IncontinenceSIDER
342Urinary tract infectionSIDER
343Urine flow decreasedOFFSIDES
344Ventricular arrhythmiaSIDER
345Viral upper respiratory tract infectionOFFSIDES
346Visceral congestionOFFSIDES
347Vision Disorders15151959CTD
348Visual ImpairmentSIDER
349Visual disturbanceOFFSIDES
350Vitamin K DeficiencyOFFSIDES
351jaundiceSIDER
352nervous system disorderSIDER
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