MetaADEDB 2.0 @ LMMD
Trichlormethiazide
(LMJSLTNSBFUCMU-UHFFFAOYSA-N)
Structure
SMILES
ClC(C1Nc2cc(Cl)c(cc2S(=O)(=O)N1)S(=O)(=O)N)Cl
Type(s)
Approved; Vet_approved
ATC code(s)
C03AA06; C03AB06; C03EA02; G01AE10
Molecular Formula:
C8H8Cl3N3O4S2
Molecular Weight:
380.656
Log P:
4.1497
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
3
TPSA:
135.12
CAS Number(s):
133-67-5
Synonym(s)
1.
Trichlormethiazide
2.
Aquazide
3.
Naqua
4.
Triazide
5.
Trichloromethiazide
External Link(s)
MeSHD014237
PubChem Compound5560
BindingDB26998
ChEBI9683
CHEMBLCHEMBL1054
DrugBankDB01021
DrugCentral2733
IUPHAR/BPS Guide to PHARMACOLOGY7314
KEGGcpd:C07767
dr:D00658
Therapeutic Target DatabaseD0Y2IZ
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Blood creatine phosphokinase increasedFAERS: 1OFFSIDES
US FAERS
2Depressed Level of ConsciousnessFAERS: 1OFFSIDES
US FAERS
3Respiratory arrestFAERS: 1US FAERS
4Abdominal massOFFSIDES
5ActinomycosisOFFSIDES
6Acute kidney injury8164396
12862209		CTD
7Adams-Stokes SyndromeOFFSIDES
8AdenitisOFFSIDES
9AdenocarcinomaOFFSIDES
10AgraphiaOFFSIDES
11Alanine Aminotransferase IncreasedOFFSIDES
12Alcohol interactionOFFSIDES
13Altered state of consciousnessOFFSIDES
14Alveolar Soft Part SarcomaOFFSIDES
15AngioplastyOFFSIDES
16AnorexiaOFFSIDES
17Anti-insulin antibody positiveOFFSIDES
18Aortic AneurysmOFFSIDES
19ApathyOFFSIDES
20Aphthous StomatitisOFFSIDES
21Arteriosclerosis ObliteransOFFSIDES
22AscitesOFFSIDES
23Atrioventricular BlockOFFSIDES
24Autoimmune thyroiditisOFFSIDES
25BicytopeniaOFFSIDES
26Blood albumin abnormalOFFSIDES
27Blood albumin decreasedOFFSIDES
28Blood alkaline phosphatase increasedOFFSIDES
29Blood corticotrophinOFFSIDES
30Blood cortisol decreasedOFFSIDES
31Blood creatinine increasedOFFSIDES
32Blood glucose decreasedOFFSIDES
33Blood immunoglobulin EOFFSIDES
34Blood immunoglobulin G increasedOFFSIDES
35Blood lactate dehydrogenase increasedOFFSIDES
36Blood potassium decreasedOFFSIDES
37Blood potassium increasedOFFSIDES
38Blood pressure inadequately controlledOFFSIDES
39Blood sodium increasedOFFSIDES
40Blood sodiumOFFSIDES
41Blood triglycerides increasedOFFSIDES
42Blood urea increasedOFFSIDES
43Blood uric acidOFFSIDES
44BradycardiaOFFSIDES
45Brain natriuretic peptide increasedOFFSIDES
46Bronchoalveolar LavageOFFSIDES
47CD4 Lymphocytes DecreasedOFFSIDES
48CD8 lymphocytes decreasedOFFSIDES
49CataractOFFSIDES
50Cell marker increasedOFFSIDES
51Cerebral artery stenosisOFFSIDES
52Chemotherapeutic drug level increasedOFFSIDES
53CholangiolitisOFFSIDES
54ChromaturiaOFFSIDES
55Color blindnessOFFSIDES
56Contact DermatitisOFFSIDES
57Cubital Tunnel SyndromeOFFSIDES
58DehydrationOFFSIDES
59Dental abscessOFFSIDES
60Detachment of retinal pigment epitheliumOFFSIDES
61Device interactionOFFSIDES
62DiabetesOFFSIDES
63Diabetic NephropathyOFFSIDES
64Disseminated Intravascular CoagulationOFFSIDES
65DizzinessOFFSIDES
66Duodenal UlcerOFFSIDES
67Duodenal perforationOFFSIDES
68EczemaOFFSIDES
69Electrocardiogram QT corrected interval shortenedOFFSIDES
70EnterocolitisOFFSIDES
71Eosinophilic PneumoniaOFFSIDES
72EpidermolysisOFFSIDES
73ExcoriationOFFSIDES
74Feeling abnormalOFFSIDES
75Gamma-Glutamyltransferase IncreasedOFFSIDES
76Gastric ulcerOFFSIDES
77GastroenteritisOFFSIDES
78Gastrointestinal perforationOFFSIDES
79Gaze palsyOFFSIDES
80Glomerulonephritis1860704CTD
81HemiplegiaOFFSIDES
82HiccoughOFFSIDES
83Hypertensive heart diseaseOFFSIDES
84Ileal ulcerOFFSIDES
85Intestinal ObstructionOFFSIDES
86IntubationOFFSIDES
87Laboratory test interferenceOFFSIDES
88Leukopenia neonatalOFFSIDES
89LipaseOFFSIDES
90Lymphocyte count decreasedOFFSIDES
91Lymphocyte stimulation test positiveOFFSIDES
92MarasmusOFFSIDES
93Markedly reduced dietary intakeOFFSIDES
94MonoplegiaOFFSIDES
95Mucosal erosionOFFSIDES
96Multiple MyelomaOFFSIDES
97Myoglobin blood increasedOFFSIDES
98NasopharyngitisOFFSIDES
99Nephrogenic Diabetes InsipidusOFFSIDES
100Nutritional condition abnormalOFFSIDES
101OliguriaOFFSIDES
102PanniculitisOFFSIDES
103Percutaneous Coronary InterventionOFFSIDES
104Peritoneal DialysisOFFSIDES
105PoriomaniaOFFSIDES
106Primary sequestrumOFFSIDES
107Productive CoughOFFSIDES
108Pulmonary congestionOFFSIDES
109Renal failure neonatalOFFSIDES
110Residual urineOFFSIDES
111RhabdomyolysisOFFSIDES
112RhinorrheaOFFSIDES
113Sinus Arrest, Cardiac1240790CTD
114Sinus bradycardiaOFFSIDES
115Small intestine carcinomaOFFSIDES
116SmallpoxOFFSIDES
117SoliloquyOFFSIDES
118Sudden deathOFFSIDES
119Surgical vascular shuntOFFSIDES
120Thrombotic strokeOFFSIDES
121Tooth ExtractionOFFSIDES
122Ventricular hypokinesiaOFFSIDES
123Wolff-Parkinson-White SyndromeOFFSIDES
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