MetaADEDB 2.0 @ LMMD
Imipenem
(ZSKVGTPCRGIANV-ZXFLCMHBSA-N)
Structure
SMILES
C[C@H]([C@@H]1[C@H]2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O
Type(s)
Approved
ATC code(s)
J01DH51
Molecular Formula:
C12H17N3O4S
Molecular Weight:
299.346
Log P:
0.2525
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
3
TPSA:
141.52
CAS Number(s):
64221-86-9; 74431-23-5; 103730-39-8
Synonym(s)
1.
Imipenem
2.
Imipemide
3.
N-Formimidoylthienamycin
4.
Imipenem Anhydrous
5.
Imipenem, Anhydrous
6.
MK-0787
7.
MK0787
8.
Anhydrous Imipenem
9.
Anhydrous, Imipenem
10.
MK 0787
11.
N Formimidoylthienamycin
External Link(s)
MeSHD015378
PubChem Compound104838
BindingDB50049708
50213266
ChEBI471744
CHEMBLCHEMBL148
DrugBankDB01598
DrugCentral1426
KEGGcpd:C06665
dr:D04515
Therapeutic Target DatabaseD0H3TD
ZINC4097225
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 31US FAERS
2SepsisFAERS: 19US FAERS
3Anaphylactic shockFAERS: 13US FAERS
4EpilepsyFAERS: 13US FAERS
5Septic ShockFAERS: 11OFFSIDES
US FAERS
6PneumoniaFAERS: 10US FAERS
7Intrauterine infectionFAERS: 9US FAERS
8Drug resistanceFAERS: 8US FAERS
9Medication ErrorFAERS: 8US FAERS
10ThrombocytopeniaFAERS: 7US FAERS
11PruritusFAERS: 6US FAERS
12Adverse eventFAERS: 5US FAERS
13Disseminated Intravascular CoagulationFAERS: 5US FAERS
14PancytopeniaFAERS: 5US FAERS
15Toxic Epidermal NecrolysisFAERS: 5US FAERS
16treatment failureFAERS: 5US FAERS
17Altered state of consciousnessFAERS: 4US FAERS
18General physical health deteriorationFAERS: 4OFFSIDES
US FAERS
19LethargyFAERS: 4US FAERS
20Pharmaceutical product complaintFAERS: 4US FAERS
21ShockFAERS: 4US FAERS
22TremorFAERS: 42769962CTD
US FAERS
23Biliary anastomosis complicationFAERS: 3US FAERS
24Duodenal ulcer perforationFAERS: 3US FAERS
25Gastrointestinal perforationFAERS: 3US FAERS
26Incorrect route of drug administrationFAERS: 3US FAERS
27InfectionFAERS: 3OFFSIDES
US FAERS
28Intestinal ObstructionFAERS: 3US FAERS
29VomitingFAERS: 32681127CTD
US FAERS
30AgitationFAERS: 2US FAERS
31Aspartate Aminotransferase IncreasedFAERS: 2US FAERS
32Cardiac ArrestFAERS: 2US FAERS
33CyanosisFAERS: 2OFFSIDES
US FAERS
34DeliriumFAERS: 2US FAERS
35Drug exposure during pregnancyFAERS: 2US FAERS
36Febrile NeutropeniaFAERS: 2OFFSIDES
US FAERS
37Feeling abnormalFAERS: 2US FAERS
38Fundoscopy abnormalFAERS: 2US FAERS
39HepatotoxicityFAERS: 2OFFSIDES
US FAERS
40HypopyonFAERS: 2US FAERS
41HypoxiaFAERS: 2OFFSIDES
US FAERS
42LeukocytosisFAERS: 2US FAERS
43MalaiseFAERS: 2US FAERS
44Mental status changesFAERS: 2US FAERS
45NeutropeniaFAERS: 2US FAERS
46PhotophobiaFAERS: 2US FAERS
47Psoas AbscessFAERS: 2US FAERS
48Rash erythematousFAERS: 2US FAERS
49Respiratory arrestFAERS: 2US FAERS
50RestlessnessFAERS: 2US FAERS
51Shunt infectionFAERS: 2US FAERS
52Status EpilepticusFAERS: 2OFFSIDES
US FAERS
53Therapy non-responderFAERS: 2OFFSIDES
US FAERS
54Urinary tract infectionFAERS: 2US FAERS
55UrticariaFAERS: 211792017CTD
US FAERS
56nervous system disorderFAERS: 2US FAERS
57Abdominal discomfortFAERS: 1US FAERS
58Accidental exposureFAERS: 1US FAERS
59Alanine Aminotransferase IncreasedFAERS: 1OFFSIDES
US FAERS
60AlopeciaFAERS: 1US FAERS
61Ammonia increasedFAERS: 1US FAERS
62Anaphylactoid ReactionFAERS: 1US FAERS
63AngioedemaFAERS: 1US FAERS
64AnxietyFAERS: 1US FAERS
65AsphyxiaFAERS: 1US FAERS
66AsthmaFAERS: 1US FAERS
67Back PainFAERS: 1US FAERS
68Blood amylase increasedFAERS: 1US FAERS
69Blood creatinine increasedFAERS: 1US FAERS
70Cardiac valve vegetationFAERS: 1US FAERS
71Catheter related infectionFAERS: 1OFFSIDES
US FAERS
72Clostridium difficile colitisFAERS: 1OFFSIDES
US FAERS
73Clostridium difficile infectionFAERS: 1US FAERS
74DeafnessFAERS: 1US FAERS
75Depressed Level of ConsciousnessFAERS: 1US FAERS
76Device FailureFAERS: 1US FAERS
77Disease recurrenceFAERS: 1US FAERS
78DisorientationFAERS: 1US FAERS
79Drug administration errorFAERS: 1US FAERS
80Electroencephalogram abnormalFAERS: 1US FAERS
81EncephalitisFAERS: 1OFFSIDES
US FAERS
82EndocarditisFAERS: 1OFFSIDES
US FAERS
83EndophthalmitisFAERS: 1US FAERS
84EosinophiliaFAERS: 1US FAERS
85ErythemaFAERS: 1OFFSIDES
US FAERS
86Escherichia infectionFAERS: 1US FAERS
87ExcitabilityFAERS: 1US FAERS
88FormicationFAERS: 1US FAERS
89GlomerulonephritisFAERS: 1US FAERS
90HemiparesisFAERS: 1US FAERS
91HepatitisFAERS: 1OFFSIDES
US FAERS
92HypercapniaFAERS: 1US FAERS
93HypersensitivityFAERS: 1US FAERS
94HypokinesiaFAERS: 1US FAERS
95Infective thrombosisFAERS: 1US FAERS
96Injection site vesiclesFAERS: 1US FAERS
97LeukopeniaFAERS: 1US FAERS
98Limb injuryFAERS: 1US FAERS
99Lipase increasedFAERS: 1US FAERS
100Liquid product physical issueFAERS: 1US FAERS
101Local reactionFAERS: 1US FAERS
102LymphangitisFAERS: 1US FAERS
103MarasmusFAERS: 1US FAERS
104Memory impairmentFAERS: 1US FAERS
105MeningitisFAERS: 1US FAERS
106Mental impairmentFAERS: 1US FAERS
107Metabolic alkalosisFAERS: 1US FAERS
108Multi-organ disorderFAERS: 1US FAERS
109NauseaFAERS: 1US FAERS
110Neuroleptic Malignant SyndromeFAERS: 1US FAERS
111No adverse effectFAERS: 1US FAERS
112OverdoseFAERS: 1OFFSIDES
US FAERS
113Pacemaker complicationFAERS: 1US FAERS
114PainFAERS: 1US FAERS
115PallorFAERS: 1US FAERS
116Pathogen resistanceFAERS: 1OFFSIDES
US FAERS
117Poor quality drug administeredFAERS: 1US FAERS
118Post procedural bile leakFAERS: 1US FAERS
119Prescribed overdoseFAERS: 1US FAERS
120Product quality issueFAERS: 1US FAERS
121Productive CoughFAERS: 1US FAERS
122Pulmonary congestionFAERS: 1US FAERS
123Refusal of treatment by relativeFAERS: 1OFFSIDES
US FAERS
124Renal tubular necrosisFAERS: 1OFFSIDES
US FAERS
125Respiratory distressFAERS: 1US FAERS
126RhabdomyolysisFAERS: 1US FAERS
127SchizophreniaFAERS: 1US FAERS
128Sense of oppressionFAERS: 1US FAERS
129SomnolenceFAERS: 1US FAERS
130SoporFAERS: 1US FAERS
131Squamous cell carcinoma of skinFAERS: 1US FAERS
132Stenotrophomonas infectionFAERS: 1US FAERS
133Stevens-Johnson SyndromeFAERS: 1OFFSIDES
US FAERS
134Sudden Cardiac DeathFAERS: 1US FAERS
135Sudden deathFAERS: 1US FAERS
136ThrombocytosisFAERS: 1US FAERS
137Ventricular arrhythmiaFAERS: 1US FAERS
138VertigoFAERS: 1US FAERS
139Vocal Cord ParalysisFAERS: 1US FAERS
140Weight decreasedFAERS: 1US FAERS
141White blood cell count abnormalFAERS: 1US FAERS
142pseudomembranous colitisFAERS: 1US FAERS
143Abdominal tendernessOFFSIDES
144AcidosisOFFSIDES
145Actinomycosis15155214CTD
146Adrenal cortex necrosisOFFSIDES
147AnorexiaOFFSIDES
148AnuriaOFFSIDES
149Aortic AneurysmOFFSIDES
150AscitesOFFSIDES
151Ataxia2669668CTD
152AutomatismOFFSIDES
153Axillary vein thrombosisOFFSIDES
154Bacillaceae Infections15155214CTD
155Band neutrophil percentage increasedOFFSIDES
156BicytopeniaOFFSIDES
157Blood chloride decreasedOFFSIDES
158Blood lactate dehydrogenase increasedOFFSIDES
159Blood pressure fluctuationOFFSIDES
160Blood urea increasedOFFSIDES
161Blood urine presentOFFSIDES
162Brain Diseases20339671CTD
163Bronchoalveolar LavageOFFSIDES
164Capillary Leak SyndromeOFFSIDES
165Cell DeathOFFSIDES
166Chemotherapeutic drug level increasedOFFSIDES
167Clostridium Infections15155214CTD
168Corynebacterium Infections15155214CTD
169Crossmatch incompatibleOFFSIDES
170DiabetesOFFSIDES
171Diarrhea2681127CTD
172Drug Eruptions11792017CTD
173Drug toxicityOFFSIDES
174Electromechanical dissociationOFFSIDES
175Enterobacteriaceae Infections16000513CTD
176Enterococcal infectionOFFSIDES
177Eosinophilic PneumoniaOFFSIDES
178Eosinophilic myocarditisOFFSIDES
179EpiglottitisOFFSIDES
180Erythema MultiformeOFFSIDES
181Escherichia sepsisOFFSIDES
182Febrile bone marrow aplasiaOFFSIDES
183Fungal peritonitisOFFSIDES
184Fungus culture positiveOFFSIDES
185Gamma-Glutamyltransferase IncreasedOFFSIDES
186Gastric mucosal lesionOFFSIDES
187GastroenteritisOFFSIDES
188Gestational DiabetesOFFSIDES
189Herpes simplex hepatitisOFFSIDES
190Hypertensive heart diseaseOFFSIDES
191Kidney Diseases7861655
18787798		CTD
192Kidney FailureOFFSIDES
193LaryngotracheitisOFFSIDES
194LeukoencephalomyelitisOFFSIDES
195Lymphocyte percentage decreasedOFFSIDES
196MalabsorptionOFFSIDES
197Mastitis bacterialOFFSIDES
198Meningitis, Bacterial16000513CTD
199Metabolic acidosisOFFSIDES
200Mycobacterium abscessus InfectionOFFSIDES
201Myoclonus9251092
15052466		CTD
202OliguriaOFFSIDES
203PROTHROMBIN TIMEOFFSIDES
204Pancreatic InsufficiencyOFFSIDES
205ParotitisOFFSIDES
206Pericardial effusionOFFSIDES
207Pneumococcal Infections1495831CTD
208Preventive surgeryOFFSIDES
209Pulmonary artery thrombosisOFFSIDES
210Respiratory FailureOFFSIDES
211Reticulocyte count decreasedOFFSIDES
212Seizures

View details

1490893
1901667
2669668
2769962
2808213
7728525
7791026
7797443
8026738
8519843
10129142
10576583
10796065
 		CTD
213Serum SicknessOFFSIDES
214Skin ErosionOFFSIDES
215Skin dystrophyOFFSIDES
216Skin necrosisOFFSIDES
217SoliloquyOFFSIDES
218Sputum culture positiveOFFSIDES
219Stem cell transplantOFFSIDES
220T-Cell LymphomaOFFSIDES
221Testicular massOFFSIDES
222Thoracic cavity drainageOFFSIDES
223Urobilin urine presentOFFSIDES
224Venoocclusive diseaseOFFSIDES
225Wound InfectionOFFSIDES
226prostatitisOFFSIDES
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