MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

dexamethasone acetate

(AKUJBENLRBOFTD-RPRRAYFGSA-N)

Structure

SMILES: CC(=O)OCC(=O)[C@@]1(O)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)F
Type(s): Approved; Investigational; Vet_approved
Molecular Formula:: C24H31FO6
Molecular Weight:: 434.498
Log P:: 2.4665
Hydrogen Bond Acceptor:: 6
Hydrogen Bond Donor:: 2
TPSA:: 100.9
CAS Number(s):: 987-24-6; 1177-87-3

Synonym(s)

dexamethasone acetate

Fortecortin

dexamethasone acetate, (6alpha,11beta)-isomer

External Link(s)

MeSH	C018038
PubChem Compound	236702
BindingDB	50103620
ChEBI	4463
CHEMBL	CHEMBL1530428
DrugBank	DB14649
DrugCentral	826
KEGG	dr:D07796 cpd:C08174
ZINC	3882068

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Anxiety	FAERS: 1		US FAERS
2	Blood immunoglobulin G increased	FAERS: 1		OFFSIDES US FAERS
3	Candidiasis	FAERS: 1		US FAERS
4	Cerebral Infarction	FAERS: 1		US FAERS
5	Drug abuse	FAERS: 1		US FAERS
6	Drug ineffective	FAERS: 1		US FAERS
7	Guillain-Barre Syndrome	FAERS: 1		US FAERS
8	Ventricular hypertrophy	FAERS: 1		US FAERS
9	Abdominal Abscess			OFFSIDES
10	Abnormal vision			OFFSIDES
11	Actinomycosis			OFFSIDES
12	Alcohol abuse			OFFSIDES
13	Amphetamines			OFFSIDES
14	Anhedonia			OFFSIDES
15	Anhidrosis			OFFSIDES
16	Anorexia			OFFSIDES
17	Ascites			OFFSIDES
18	Asthenia			OFFSIDES
19	Atrial tachycardia			OFFSIDES
20	Bicuspid aortic valve			OFFSIDES
21	Bladder neck obstruction			OFFSIDES
22	Bladder tamponade			OFFSIDES
23	Blood blister			OFFSIDES
24	Blood chloride decreased			OFFSIDES
25	Blood creatine increased			OFFSIDES
26	Blood creatinine decreased			OFFSIDES
27	Blood immunoglobulin A increased			OFFSIDES
28	Blood sodium			OFFSIDES
29	Bone lesion			OFFSIDES
30	Bone pain			OFFSIDES
31	Bronchoalveolar Lavage			OFFSIDES
32	Bulbar palsy			OFFSIDES
33	Catheter placement			OFFSIDES
34	Cerebral aspergillosis			OFFSIDES
35	Cerumen removal			OFFSIDES
36	Choking sensation			OFFSIDES
37	Chylothorax			OFFSIDES
38	Compression fracture			OFFSIDES
39	Concomitant disease progression			OFFSIDES
40	Congenital heart disease			OFFSIDES
41	Contralateral breast cancer			OFFSIDES
42	Craniosynostosis			OFFSIDES
43	Creatinine renal clearance increased			OFFSIDES
44	Cyanosis			OFFSIDES
45	Demyelination			OFFSIDES
46	Dental Fistula			OFFSIDES
47	Dental abscess			OFFSIDES
48	Depressive disorder		8780495	CTD
49	Diarrhea			OFFSIDES
50	Disease Progression			OFFSIDES
51	Diverticulitis			OFFSIDES
52	Drowsiness			OFFSIDES
53	Drug exposure during pregnancy			OFFSIDES
54	Emotional distress			OFFSIDES
55	Endodontic procedure			OFFSIDES
56	Enteritis			OFFSIDES
57	Enterocolitis			OFFSIDES
58	Epidermolysis			OFFSIDES
59	Epidural Abscess			OFFSIDES
60	Epistaxis			OFFSIDES
61	Fatigue			OFFSIDES
62	Febrile Neutropenia			OFFSIDES
63	Fistula repair			OFFSIDES
64	Gamma-Glutamyltransferase Increased			OFFSIDES
65	General nutrition disorder			OFFSIDES
66	General physical condition			OFFSIDES
67	General physical health deterioration			OFFSIDES
68	Gestational Diabetes			OFFSIDES
69	Glioblastoma Multiforme			OFFSIDES
70	Glioblastoma			OFFSIDES
71	Haematotoxicity			OFFSIDES
72	Hemiparesis			OFFSIDES
73	Hepatotoxicity			OFFSIDES
74	Histology			OFFSIDES
75	Hydronephrosis			OFFSIDES
76	Hypertensive heart disease			OFFSIDES
77	Hypophagia			OFFSIDES
78	Incontinence			OFFSIDES
79	Infection			OFFSIDES
80	Insulin C-peptide decreased			OFFSIDES
81	Intention tremor			OFFSIDES
82	Intermittent Claudication			OFFSIDES
83	Intervertebral disc disorder			OFFSIDES
84	Intestinal Obstruction			OFFSIDES
85	Joint prosthesis user			OFFSIDES
86	Large intestine perforation			OFFSIDES
87	Laryngospasm			OFFSIDES
88	Leukopenia neonatal			OFFSIDES
89	Livedo Reticularis			OFFSIDES
90	Loose tooth			OFFSIDES
91	Lymphedema			OFFSIDES
92	Malignant neoplasm progression			OFFSIDES
93	Mastication disorder			OFFSIDES
94	Metastatic Renal Cell Carcinoma			OFFSIDES
95	Mononeuritis			OFFSIDES
96	Multiple Myeloma			OFFSIDES
97	Musculoskeletal Pain			OFFSIDES
98	Musculoskeletal discomfort			OFFSIDES
99	Nausea			OFFSIDES
100	Neurogenic Bowel			OFFSIDES
101	Neutropenic infection			OFFSIDES
102	Ocular icterus			OFFSIDES
103	Oliguria			OFFSIDES
104	Oral Cavity Fistula			OFFSIDES
105	Osteomyelitis			OFFSIDES
106	Osteotomy			OFFSIDES
107	Pain			OFFSIDES
108	Pancreatic enzymes increased			OFFSIDES
109	Paraplegia			OFFSIDES
110	Physical disability			OFFSIDES
111	Plasmacytoma			OFFSIDES
112	Pneumothorax			OFFSIDES
113	Polyneuropathy			OFFSIDES
114	Polyuria			OFFSIDES
115	Postrenal failure			OFFSIDES
116	Primary sequestrum			OFFSIDES
117	Purulent discharge			OFFSIDES
118	Respiratory Failure			OFFSIDES
119	Reticulocyte count increased			OFFSIDES
120	Rhabdomyosarcoma			OFFSIDES
121	Rhinitis			OFFSIDES
122	Rhonchi			OFFSIDES
123	Risus sardonicus			OFFSIDES
124	Septic Shock			OFFSIDES
125	Sequestrectomy			OFFSIDES
126	Sleep disorder due to general medical condition, insomnia type			OFFSIDES
127	Splenectomy			OFFSIDES
128	Stem cell transplant			OFFSIDES
129	Sudden death			OFFSIDES
130	Systemic mycosis			OFFSIDES
131	Thoracic vertebral fracture			OFFSIDES
132	Thrombophlebitis			OFFSIDES
133	Tongue biting			OFFSIDES
134	Tooth Extraction			OFFSIDES
135	Tooth Loss			OFFSIDES
136	Transaminases increased			OFFSIDES
137	Vascular calcification			OFFSIDES
138	Venous occlusion			OFFSIDES
139	Vertebroplasty			OFFSIDES
140	Very low density lipoprotein increased			OFFSIDES
141	Wound Infection			OFFSIDES
142	fibroma			OFFSIDES

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