MetaADEDB 2.0 @ LMMD
Permethrin
(RLLPVAHGXHCWKJ-UHFFFAOYSA-N)
Structure
SMILES
ClC(=CC1C(C1(C)C)C(=O)OCc1cccc(c1)Oc1ccccc1)Cl
Type(s)
Approved; Investigational
ATC code(s)
P03AC04; P03AC54
Molecular Formula:
C21H20Cl2O3
Molecular Weight:
391.288
Log P:
6.1133
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
0
TPSA:
35.53
CAS Number(s):
52341-32-9; 52341-33-0; 52645-53-1; 93389-07-2
Synonym(s)
1.
Permethrin
2.
(m-Phenoxybenzyl)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
3.
3-Phenoxybenzyl-(+-)-cis,trans-2,2-dichlorovinyl-2,2-dimethyl-cyclopropylcarboxylic acid, ester
4.
3-Phenoxybenzyl-cis,trans-(1RS)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
5.
Ambush
6.
Elimite
7.
FMC-33297
8.
NIA-33297
9.
NRDC-143
10.
NRDC-147
11.
Nittifor
12.
PP-557
13.
Permethrin, (1R-cis)-Isomer
14.
Permethrin, (1R-trans)-Isomer
15.
Permethrin, (1S-cis)-Isomer
16.
Permethrin, (1S-trans)-Isomer
17.
Permethrin, (cis)-Isomer
18.
Permethrin, (cis-(+-))-Isomer
19.
Permethrin, (trans)-Isomer
20.
Permethrin, (trans-(+-))-Isomer
21.
Permethrin, trans-(1RS)-Isomer
22.
S-3151
23.
cis-(1RS)-permethrin
24.
cis-permethrin
25.
permethrin, cis-(1RS)-isomer
26.
trans-(1RS)-Permethrin
27.
trans-permethrin
28.
FMC 33297
29.
FMC33297
30.
NIA 33297
31.
NIA33297
32.
NRDC 143
33.
NRDC 147
34.
NRDC143
35.
NRDC147
36.
PP 557
37.
PP557
38.
S 3151
39.
S3151
40.
cis permethrin
41.
trans permethrin
External Link(s)
MeSHD026023
PubChem Compound40326
ChEBI34911
CHEMBLCHEMBL1525
DrugBankDB04930
DrugCentral4152
KEGGcpd:C14388
dr:D05443
Therapeutic Target DatabaseD0K8MP
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 48
Canada Vigilance: 41		Canada Vigilance
US FAERS
2Inappropriate schedule of drug administrationFAERS: 31US FAERS
3PruritusFAERS: 15
Canada Vigilance: 3		Canada Vigilance
SIDER
US FAERS
4Wrong technique in product usage processFAERS: 10US FAERS
5No adverse eventFAERS: 9US FAERS
6Inappropriate schedule of product administrationFAERS: 8US FAERS
7Application site pruritusFAERS: 7US FAERS
8Burning sensationFAERS: 7US FAERS
9Incorrect drug administration durationFAERS: 7US FAERS
10AlopeciaFAERS: 6US FAERS
11Application site painFAERS: 6US FAERS
12ErythemaFAERS: 6SIDER
US FAERS
13PainFAERS: 6SIDER
US FAERS
14Application site erythemaFAERS: 5US FAERS
15Drug ineffective for unapproved indicationFAERS: 5US FAERS
16HypersensitivityFAERS: 5US FAERS
17NauseaFAERS: 5
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
18Application site rashFAERS: 4US FAERS
19Incorrect product administration durationFAERS: 4US FAERS
20OverdoseFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
21Product physical consistency issueFAERS: 4US FAERS
22VomitingFAERS: 4SIDER
US FAERS
23AcarodermatitisFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
24Application site burnFAERS: 3US FAERS
25Drug toxicityFAERS: 3US FAERS
26Dry skinFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
27FormicationFAERS: 3US FAERS
28Infantile apnoeic attackFAERS: 3US FAERS
29Intentional product misuseFAERS: 3US FAERS
30MalaiseFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
31Musculoskeletal stiffnessFAERS: 3US FAERS
32StaringFAERS: 3US FAERS
33UrticariaFAERS: 3US FAERS
34Abdominal PainFAERS: 2SIDER
US FAERS
35Adverse eventFAERS: 2US FAERS
36Application site irritationFAERS: 2US FAERS
37Application site papulesFAERS: 2US FAERS
38Application site swellingFAERS: 2US FAERS
39Arthropod biteFAERS: 2US FAERS
40ChoreoathetosisFAERS: 2US FAERS
41Drug administration errorFAERS: 2US FAERS
42Erythema MultiformeFAERS: 2US FAERS
43Expired product administeredFAERS: 2
Canada Vigilance: 2		Canada Vigilance
US FAERS
44Extra dose administeredFAERS: 2US FAERS
45Eye irritationFAERS: 2US FAERS
46Eye painFAERS: 2US FAERS
47FatigueFAERS: 2US FAERS
48HeadacheFAERS: 2SIDER
US FAERS
49InfectionFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
50Joint swellingFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
51MiliariaFAERS: 2US FAERS
52Product physical issueFAERS: 2US FAERS
53Skin UlcerFAERS: 2US FAERS
54Abdominal discomfortFAERS: 1US FAERS
55Accidental exposure to productFAERS: 1US FAERS
56AgeusiaFAERS: 1US FAERS
57Application site drynessFAERS: 1US FAERS
58Application site urticariaFAERS: 1US FAERS
59Application site vesiclesFAERS: 1US FAERS
60CarotidyniaFAERS: 1US FAERS
61CellulitisFAERS: 1US FAERS
62Chemical injuryFAERS: 1US FAERS
63DeliriumFAERS: 1US FAERS
64DermatitisFAERS: 1SIDER
US FAERS
65Disease recurrenceFAERS: 1US FAERS
66DizzinessFAERS: 1SIDER
US FAERS
67Drug abuseFAERS: 1US FAERS
68Drug administered at inappropriate siteFAERS: 1US FAERS
69Drug effect incompleteFAERS: 1US FAERS
70Drug screen positiveFAERS: 1US FAERS
71Feeling abnormalFAERS: 1US FAERS
72HypotensionFAERS: 1US FAERS
73Incorrect dose administeredFAERS: 1US FAERS
74Incorrect route of drug administrationFAERS: 1US FAERS
75Joint stiffnessFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
76Lip swellingFAERS: 1US FAERS
77LymphadenopathyFAERS: 1US FAERS
78Medication ErrorFAERS: 1US FAERS
79Medication residue presentFAERS: 1US FAERS
80MyalgiaFAERS: 127058124CTD
US FAERS
81Occupational exposure to productFAERS: 1US FAERS
82Peripheral swellingFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
83Poor quality drug administeredFAERS: 1US FAERS
84Product administered at inappropriate siteFAERS: 1US FAERS
85Product container seal issueFAERS: 1US FAERS
86Product label issueFAERS: 1US FAERS
87Product quality issueFAERS: 1US FAERS
88Product residue presentFAERS: 1US FAERS
89SomnolenceFAERS: 1US FAERS
90Therapeutic response unexpectedFAERS: 1US FAERS
91TremorFAERS: 13088650
28456543
29893952		CTD
US FAERS
92TrichorrhexisFAERS: 1US FAERS
93treatment failureFAERS: 1US FAERS
94Adenoma28431163CTD
95Agricultural Workers' Diseases

View details

17932376
17975796
20730623
20818537
23916637
 		CTD
96Aneuploidy28624474
30763314		CTD
97Application site injuryCanada Vigilance: 1Canada Vigilance
98Asthenozoospermia18455858CTD
99Asthma17932376CTD
100Ataxia19748519CTD
101Auditory Perceptual Disorders29893952CTD
102Bronchitis, Chronic17975796CTD
103Chemical and Drug Induced Liver Injury24121187CTD
104Cognition Disorders25785457CTD
105Colonic Neoplasms20730623CTD
106Craniofacial Abnormalities19861644CTD
107Depressive disorder23916637CTD
108DiscomfortCanada Vigilance: 1Canada Vigilance
109Dystonia15843294CTD
110Gastrointestinal PainSIDER
111Gliosis25785457CTD
112Heart Diseases21616133
23806482		CTD
113Hypokinesia20019907CTD
114Infertility30763314CTD
115Inflammation21235202CTD
116Insect Bites and Stings12749493
12971516
15189238		CTD
117Intestinal Diseases29751049CTD
118Kidney Diseases24121187CTD
119Kidney Failure, Chronic26177651CTD
120LethargyCanada Vigilance: 1Canada Vigilance
121Lice Infestations21268748
21337951		CTD
122Liver neoplasms30629241CTD
123Lung Neoplasms28431163CTD
124Memory Disorders27984134CTD
125Micronuclei, Chromosome-Defective27502151CTD
126Mobility Limitation29803855CTD
127Multiple Myeloma25018334
25337994		CTD
128Necrosis15036745CTD
129Nerve Degeneration23174539CTD
130NumbnessSIDER
131Oligospermia18455858CTD
132Parkinson Disease25461423CTD
133Penile swellingCanada Vigilance: 1Canada Vigilance
134Persian Gulf Syndrome

View details

25785457
27058124
27984134
28659758
29751049
29803855
30503814
 		CTD
135PiloerectionCanada Vigilance: 1Canada Vigilance
136Poisoning28742096
28743278		CTD
137Product administered to patient of inappropriate ageCanada Vigilance: 1Canada Vigilance
138Product administration errorCanada Vigilance: 4Canada Vigilance
139Prostatic Neoplasms20978189CTD
140Respiratory Sounds27384423CTD
141Rhinitis20818537CTD
142Seizures19748519CTD
143Skin irritationCanada Vigilance: 2Canada Vigilance
144Skin lesionCanada Vigilance: 1Canada Vigilance
145Spasm31442592CTD
146SwellingCanada Vigilance: 1Canada Vigilance
147Testicular Diseases21745691CTD
148Therapeutic product effect incompleteCanada Vigilance: 1Canada Vigilance
149leukemia12937054CTD
150nervous system disorderCanada Vigilance: 1Canada Vigilance
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