MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Cyproterone

(DUSHUSLJJMDGTE-ZJPMUUANSA-N)

Structure

SMILES: O=C1C=C2C(=C[C@@H]3[C@@H]([C@]2([C@@H]2[C@H]1C2)C)CC[C@]1([C@H]3CC[C@]1(O)C(=O)C)C)Cl
Molecular Formula:: C22H27ClO3
Molecular Weight:: 374.901
Log P:: 4.0368
Hydrogen Bond Acceptor:: 3
Hydrogen Bond Donor:: 1
TPSA:: 54.37
CAS Number(s):: 2098-66-0

Synonym(s)

Cyproterone

Cyproterone, 1alpha,2 alpha,9 beta,10 alpha-Isomer

External Link(s)

MeSH	D003534
PubChem Compound	5284537
ChEBI	50742
CHEMBL	CHEMBL142130
KEGG	dr:D07766
ZINC	12504523

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Abdominal Pain	Canada Vigilance: 1		Canada Vigilance SIDER
2	Abnormal vision			SIDER
3	Acne Vulgaris			SIDER
4	Acne	Canada Vigilance: 1		Canada Vigilance SIDER
5	Activated Protein C Resistance		15333036	CTD
6	Acute Coronary Syndrome			SIDER
7	Agitation			SIDER
8	Alanine Aminotransferase Increased			SIDER
9	Alopecia			SIDER
10	Anemia, Macrocytic		9169341	CTD
11	Anorexia		9169341	CTD SIDER
12	Aphasia			SIDER
13	Ascites			SIDER
14	Aspartate Aminotransferase Increased			SIDER
15	Asthenia			SIDER
16	Asthma			SIDER
17	Azoospermia			SIDER
18	Blindness			SIDER
19	Blood and lymphatic system disorders			SIDER
20	Blood cortisol decreased			SIDER
21	Blood creatinine increased			SIDER
22	Breast tenderness			SIDER
23	Cerebrovascular accident			SIDER
24	Chills			SIDER
25	Constipation			SIDER
26	Creatinine increased			SIDER
27	Crystalluria			SIDER
28	Cyst			SIDER
29	Depressed mood			SIDER
30	Dermatitis			SIDER
31	Diabetes Mellitus			SIDER
32	Discomfort			SIDER
33	Disturbance in sexual arousal			SIDER
34	Dizziness			SIDER
35	Dry skin			SIDER
36	Dyspepsia			SIDER
37	Eczema			SIDER
38	Embolism			SIDER
39	Embolus			SIDER
40	Erectile dysfunction			SIDER
41	Erythema Nodosum			SIDER
42	Extravasation			SIDER
43	Familial Testotoxicosis		19209621	CTD
44	Fatigue	Canada Vigilance: 1	9169341	CTD SIDER Canada Vigilance
45	Febrile Neutropenia			SIDER
46	Feeling abnormal			SIDER
47	Fertilization			SIDER
48	Folic Acid Deficiency		9169341	CTD
49	Gastrointestinal Pain			SIDER
50	Glossitis			SIDER
51	Headache		9169341	CTD SIDER
52	Hemiplegia			SIDER
53	Hepatic necrosis			SIDER
54	Hepatitis			SIDER
55	Hepatomegaly			SIDER
56	Hepatotoxicity			SIDER
57	Hernia			SIDER
58	Hirsutism			SIDER
59	Hypersensitivity			SIDER
60	Hyperventilation			SIDER
61	Hypotension			SIDER
62	Infertility			SIDER
63	Injection Site Reaction			SIDER
64	Lassitude			SIDER
65	Leukocytosis			SIDER
66	Leukopenia			SIDER
67	Malaise	Canada Vigilance: 1		Canada Vigilance SIDER
68	Malnutrition			SIDER
69	Meningioma			SIDER
70	Menorrhagia	Canada Vigilance: 1		Canada Vigilance
71	Myocardial Infarction			SIDER
72	Nausea			SIDER
73	Nitrogen balance negative			SIDER
74	Nodular regenerative hyperplasia			SIDER
75	Nodule			SIDER
76	Normocytic anemia			SIDER
77	Optic Atrophy			SIDER
78	Optic Neuritis			SIDER
79	Osteoporosis			SIDER
80	Ovulation inhibited			SIDER
81	Pain			SIDER
82	Pancreatitis			SIDER
83	Phlebitis			SIDER
84	Prostatic Neoplasms		15503741	CTD
85	Pruritus			SIDER
86	Pulmonary Embolism			SIDER
87	Pulmonary Fibrosis			SIDER
88	Retinal Vascular Disorder			SIDER
89	Scleroderma			SIDER
90	Shock			SIDER
91	Skin Ulcer		9169341	CTD
92	Sleep Initiation and Maintenance Disorders		9169341	CTD
93	Spermatozoa abnormal			SIDER
94	Sweating			SIDER
95	Syncope			SIDER
96	Tachycardia		9169341	CTD SIDER
97	Tension			SIDER
98	Thrombocytopenia			SIDER
99	Thrombophlebitis			SIDER
100	Thrombosis			SIDER
101	Urticaria			SIDER
102	Uterine fibroids enlarged			SIDER
103	Vaginal Discharge			SIDER
104	Venous Thromboembolism		11705493	CTD
105	Visual Impairment			SIDER
106	Vomiting			SIDER
107	Weight decreased			SIDER
108	jaundice			SIDER

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