MetaADEDB 2.0 @ LMMD
Insulin
(YAJCHEVQCOHZDC-QMMNLEPNSA-N)
Structure
SMILES
NCCCC[C@@H](C(=O)N[C@H](C(=O)O)[C@@H](O)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H]([C@@H](O)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccc(cc2)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](Cc2ccc(cc2)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H]2CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H]([C@@H](CC)C)NC(=O)CN)CCC(=O)O)CCC(=O)N)C(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)C(C)C)CC(C)C)Cc1ccc(cc1)O)CC(C)C)C)CCC(=O)O)C(C)C)CC(C)C)Cc1c[nH]cn1)CO)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C(=O)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc1ccccc1)N)CCC(=O)N)Cc1c[nH]cn1)CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)[C@@H](CC)C)CO)[C@@H](O)C)C(=O)N[C@H](C(=O)O)CC(=O)N)CCC(=O)O)CCCNC(=N)N)Cc1ccccc1)Cc1ccc(cc1)O
Molecular Formula:
C256H381N65O77S6
Molecular Weight:
5793.540
Log P:
4.8177
Hydrogen Bond Acceptor:
146
Hydrogen Bond Donor:
78
TPSA:
2450.87
CAS Number(s):
9004-10-8
Synonym(s)
1.
Insulin
2.
Iletin
3.
Insulin A Chain
4.
Insulin B Chain
5.
Insulin, Regular
6.
Novolin
7.
Sodium Insulin
8.
Soluble Insulin
9.
Chain, Insulin B
10.
Insulin, Sodium
11.
Insulin, Soluble
12.
Regular Insulin
External Link(s)
MeSHC473734
D007328
PubChem Compound70678557
ChEBI5931
Therapeutic Target DatabaseD06SVW
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Blood glucose increasedFAERS: 20US FAERS
2Chest PainFAERS: 12US FAERS
3Blood glucose decreasedFAERS: 8US FAERS
4AstheniaFAERS: 6US FAERS
5Chest discomfortFAERS: 6US FAERS
6Myocardial InfarctionFAERS: 6US FAERS
7DizzinessFAERS: 5US FAERS
8Anaphylactic shockFAERS: 4US FAERS
9BlindnessFAERS: 4US FAERS
10Drug exposure during pregnancyFAERS: 4US FAERS
11Drug ineffectiveFAERS: 4US FAERS
12DysgeusiaFAERS: 4US FAERS
13MalaiseFAERS: 4US FAERS
14PalpitationsFAERS: 4US FAERS
15Pharmaceutical product complaintFAERS: 4US FAERS
16ShockFAERS: 4US FAERS
17SwellingFAERS: 4US FAERS
18Throat irritationFAERS: 4US FAERS
19Coronary Artery DiseaseFAERS: 3US FAERS
20Diabetes MellitusFAERS: 3US FAERS
21FatigueFAERS: 3US FAERS
22HeadacheFAERS: 3US FAERS
23Incorrect dose administeredFAERS: 3US FAERS
24Medication ErrorFAERS: 3US FAERS
25PneumoniaFAERS: 3US FAERS
26Productive CoughFAERS: 3US FAERS
27Accidental exposureFAERS: 2US FAERS
28AsthmaFAERS: 2US FAERS
29Atrial FibrillationFAERS: 2US FAERS
30Cardiac ArrestFAERS: 2US FAERS
31Cerebrovascular accidentFAERS: 2US FAERS
32ChokingFAERS: 2US FAERS
33Diabetic RetinopathyFAERS: 2US FAERS
34DisorientationFAERS: 2US FAERS
35Drug exposure via breast milkFAERS: 2US FAERS
36KetoacidosisFAERS: 2US FAERS
37PresyncopeFAERS: 2US FAERS
38Pulmonary function test decreasedFAERS: 2US FAERS
39Respiratory distressFAERS: 2US FAERS
40SepsisFAERS: 2US FAERS
41Abdominal PainFAERS: 1US FAERS
42Angina PectorisFAERS: 1US FAERS
43AngioplastyFAERS: 1US FAERS
44Blood GlucoseFAERS: 1US FAERS
45Blood glucose fluctuationFAERS: 1US FAERS
46Burning sensationFAERS: 1US FAERS
47Circumstance or information capable of leading to medication errorFAERS: 1US FAERS
48Device malfunctionFAERS: 1US FAERS
49Diabetes mellitus inadequate controlFAERS: 1US FAERS
50DyspepsiaFAERS: 1US FAERS
51DysphoniaFAERS: 1US FAERS
52ErythemaFAERS: 1US FAERS
53Feeling abnormalFAERS: 1US FAERS
54GastritisFAERS: 1US FAERS
55HomicideFAERS: 1US FAERS
56HypersensitivityFAERS: 1US FAERS
57HypothyroidismFAERS: 1US FAERS
58IncoherentFAERS: 1US FAERS
59InflammationFAERS: 1US FAERS
60Memory impairmentFAERS: 1US FAERS
61Mental status changesFAERS: 1US FAERS
62Musculoskeletal chest painFAERS: 1US FAERS
63Musculoskeletal stiffnessFAERS: 1US FAERS
64NauseaFAERS: 1US FAERS
65NeuropathyFAERS: 1US FAERS
66No adverse effectFAERS: 1US FAERS
67No adverse eventFAERS: 1US FAERS
68No adverse reactionFAERS: 1US FAERS
69Oral candidiasisFAERS: 1US FAERS
70Pancreatic carcinomaFAERS: 1US FAERS
71Pharyngolaryngeal PainFAERS: 1US FAERS
72Poor quality drug administeredFAERS: 1US FAERS
73PregnancyFAERS: 1US FAERS
74StillbirthFAERS: 1US FAERS
75StressFAERS: 1US FAERS
76TuberculosisFAERS: 1US FAERS
77UrticariaFAERS: 1US FAERS
78Uterine contractions during pregnancyFAERS: 1US FAERS
79VomitingFAERS: 1US FAERS
80WheezingFAERS: 1US FAERS
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