MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

benserazide, levodopa drug combination

(QFLMOYQNYBDXMT-ZCMDIHMWSA-N)

Structure

SMILES: OC(=O)[C@H](Cc1ccc(c(c1)O)O)N.OCC(C(=O)NNCc1ccc(c(c1O)O)O)N
Molecular Formula:: C19H26N4O9
Molecular Weight:: 454.431
Log P:: 0.4784
Hydrogen Bond Acceptor:: 13
Hydrogen Bond Donor:: 11
TPSA:: 251.85
CAS Number(s):: 37270-69-2

Synonym(s)

benserazide, levodopa drug combination

Ro 8-0576

Ro 8-0576-12

Ro 8-0576-7

benserazide - levodopa

madopa

madopar

modopar

External Link(s)

MeSH	C005177
PubChem Compound	123809

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Catalepsy	7957769 8177909	CTD
2	Chorea	6842240 14757136	CTD
3	Confusion	2046949	CTD
4	Dyskinesia, Drug-Induced	View details 742858 1591961 2239493 6529518 8106150 10078726 11166288 11300719 11520128 12373562 12465055 12524151 14526427 14757136 15056471 15474360 15514976 15837582 16023708 16029219 16095907 16127720 16325337 16365282 16437566 16739115 16950226 17350277 17452372 17553556 17596448 17868931 17933546 18160641 18175345 18281903 18545986 18704766 18762218 18847536 19039008 19146929 19500572 19615446 19733554 19895663 20014115 20452426 20456008 20570206 20623773 20631586 20882603 20966038 21129389 21163338	CTD
5	Dystonia	View details 2239493 14526427 14757136 19319462	CTD
6	Fever	2046949	CTD
7	Gliosis	31381935	CTD
8	Hallucinations	2046949 12815666	CTD
9	Hypokinesia	742858 28185818 31381935	CTD
10	Meige Syndrome	6842240	CTD
11	Motor Skills Disorders	19196941	CTD
12	Movement Disorders	View details 944392 16817869 17596448 18434508 20434491	CTD
13	Muscle Rigidity	2046949	CTD
14	Muscle Weakness	28185818 31381935	CTD
15	Mutism	2046949	CTD
16	Myoclonus	7439114	CTD
17	Neurobehavioral Manifestations	28185818	CTD
18	Parkinson Disease	View details 56427 388600 742858 773080 785578 805381 944392 1095374 1977408 2239493 2691069 3094036 8635184 9523741 9617515 9771801 11437169 12165940 12588639 15314141 19185020	CTD
19	Parkinsonian Disorders	View details 1591961 6122974 8106150 11166288 11520128 12373562 12774329 14757136 15056471 15514976 15837582 16029219 16437566 16739115 16950226 17350277 18160641 18175345 18952677 20014115 20456008 20570206 20966038	CTD
20	Psychoses, Substance-Induced	20966038	CTD
21	Restless Legs Syndrome	17230484	CTD
22	Schizophrenia	706	CTD
23	Seizures	8471829	CTD
24	Sleep Wake Disorders	11437169	CTD
25	Substance Withdrawal Syndrome	15314141	CTD
26	Tremor	12588639	CTD
27	Wallerian Degeneration	31381935	CTD

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