MetaADEDB 2.0 @ LMMD
Malaria
(UMLS:C0024530)
Definition:
A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
UMLS ID:
C0024530
MeSH ID:
D008288
Classification:
Name:
Parasitic Diseases
MeSH Tree Number(s):
C03.752.530
Synonym(s)
1.
Malaria
2.
Cameroon fever
3.
Cameroon; fever
4.
Corsican fever
5.
Disease caused by Plasmodiidae
6.
Disease due to Plasmodiidae
7.
MALARIA
8.
Malaria, NOS
9.
Malaria, unspecified
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1atovaquone, proguanil drug combinationFAERS: 89
Canada Vigilance: 8		Canada Vigilance
OFFSIDES
US FAERS
2IvermectinFAERS: 57US FAERS
3Imatinib MesylateFAERS: 34US FAERS
4Imatinib MesylateFAERS: 15US FAERS
5MefloquineFAERS: 14US FAERS
6IvermectinFAERS: 13OFFSIDES
US FAERS
7TenofovirFAERS: 12US FAERS
8FinasterideFAERS: 3US FAERS
9Fingolimod HydrochlorideFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
10HydroxyureaFAERS: 3US FAERS
11SertralineFAERS: 3US FAERS
12Artemether, Lumefantrine Drug CombinationFAERS: 2US FAERS
13AtovaquoneFAERS: 210447880
16256055		CTD
US FAERS
14DiclofenacFAERS: 2US FAERS
15DoxycyclineFAERS: 28619448
12649241
17826578		CTD
US FAERS
16DutasterideFAERS: 2OFFSIDES
US FAERS
17LacosamideFAERS: 2US FAERS
18LenalidomideFAERS: 2US FAERS
19NevirapineFAERS: 2OFFSIDES
US FAERS
20Sitagliptin PhosphateFAERS: 2US FAERS
21SunitinibFAERS: 2US FAERS
224-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamideFAERS: 1US FAERS
23Aspirin, Dipyridamole Drug CombinationFAERS: 1US FAERS
24Atovaquone and proguanil hydrochlorideFAERS: 1
Canada Vigilance: 2		Canada Vigilance
US FAERS
25CitalopramFAERS: 1US FAERS
26CitalopramFAERS: 1US FAERS
27ClozapineFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
28DasatinibFAERS: 1US FAERS
29Emtricitabine, Tenofovir Disoproxil Fumarate Drug CombinationFAERS: 1US FAERS
30Glatiramer AcetateFAERS: 1US FAERS
31Medroxyprogesterone AcetateFAERS: 1US FAERS
32MefloquineFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
33Quetiapine FumarateFAERS: 1US FAERS
34Sildenafil CitrateFAERS: 1US FAERS
35SorafenibFAERS: 1US FAERS
36ThalidomideFAERS: 1US FAERS
37abacavirFAERS: 1US FAERS
38cefuroxime axetilFAERS: 1US FAERS
39ponatinibFAERS: 1US FAERS
40tafenoquineFAERS: 1US FAERS
41Amodiaquine

View details

851793
974497
3651930
14717048
19059302
 		CTD
42Artemether15934850CTD
43Artesunate

View details

15107507
19513562
20144594
20194698
25071004
26340163
28712788
 		CTD
44Astemizole16816845CTD
45BleomycinOFFSIDES
46Calcium Compounds9785681CTD
47CefaclorOFFSIDES
48Chloroquine

View details

200890
457222
851793
1029911
1486619
1665944
1888972
2051527
2831692
3029852
3371193
4776885
4864652
6335683
6366489
7310924
7325735
7762925
8099690
8772850
9632091
11130385
11675058
12962582
17202178
17341043
17667217
18061791
18343736
18720672
19198858
19393257
19784824
24781711
 		CTD
49Chlorpromazine23129054CTD
50Ciprofloxacin7596948CTD
51CyclizineOFFSIDES
52Cyproheptadine23129054CTD
53Dapsone18602405CTD
54DiatrizoateSIDER
55DiazepamOFFSIDES
56EthambutolOFFSIDES
57Hydroxychloroquine17202178
18061791		CTD
58Imipramine23129054CTD
59Ketotifen23129054CTD
60LamivudineOFFSIDES
61Lumefantrine15934850
24561477		CTD
62Maloprim

View details

1124444
4776885
17160201
20193682
 		CTD
OFFSIDES
63MedroxyprogesteroneOFFSIDES
64Mefloquine

View details

2569094
2694482
7486482
7859199
7935106
7944858
8099690
8287786
8780466
9394947
9882160
10457122
11179947
11449039
12649241
12962582
16012293
17826578
20058779
 		CTD
OFFSIDES
65Primaquine

View details

4864652
6366489
7325735
9813483
11303037
19616568
20194698
26477383
 		CTD
66Proguanil

View details

1124444
1888972
3651930
8099690
16256055
 		CTD
67Protriptyline23129054CTD
68PyrazinamideOFFSIDES
69PyridoxineOFFSIDES
70Quinidine8957602CTD
71Quinine

View details

1796238
1896775
2406680
8116811
8619448
8957602
15107507
18717145
18807436
 		CTD
72Raltegravir PotassiumCanada Vigilance: 1Canada Vigilance
73StreptomycinOFFSIDES
74SulindacOFFSIDES
75TenofovirOFFSIDES
76Testosterone15788153CTD
77Tetracycline8116811CTD
OFFSIDES
78Trimethoprim, Sulfamethoxazole Drug CombinationOFFSIDES
79Trimipramine23129054CTD
80VinblastineOFFSIDES
81abacavirOFFSIDES
82artemisinine16919048CTD
83artemotil19555804CTD
84borrelidin21343942
23488671
25489076		CTD
85chloroquine diphosphate458905
638620
1232932		CTD
86desmethylastemizole16816845CTD
87efavirenzOFFSIDES
88fanasil, pyrimethamine drug combination

View details

3371193
6335683
7325735
15934850
16012293
17617910
18008240
18008241
18008242
20194698
 		CTD
89ferroquine24781711CTD
90frenolicin B22008701CTD
91halofantrine8116811
15934850
17404338		CTD
92lamivudine, zidovudine drug combinationOFFSIDES
93mefloquine-sulfadoxine-pyrimethamine2694482CTD
94mururin A23354072CTD
95poliothrysoside20457242CTD
Similar ADE(s)
NameSemantic Similarity
1Amebiasis42.9%
2Coccidiosis42.9%
3Acanthamoeba Infection42.9%
4Trichomonas Infections42.9%
5Ciliophora Infections42.9%
6Balamuthia Infection42.9%
7Entamoebiasis31%
8Toxoplasmosis31%
9Trypanosomiasis31%
10Isosporiasis31%
11Protozoan Infections, Animal28.6%
12Babesiosis28.4%
13Giardiasis27.8%
14Leishmaniasis, Visceral25.4%
15African Trypanosomiasis25.4%
16Chagas Disease25.4%
17Cryptosporidiosis24.2%
18Helminthiasis23.1%
19Leishmaniasis22.2%
20Trichomonas Vaginitis20.1%
21Acanthamoeba Keratitis17.8%
22Leishmaniasis, Cutaneous17.4%
23Parasitic Diseases, Animal15.8%
24Chagas Cardiomyopathy15.1%
25Liver Diseases, Parasitic15%
26Intestinal Diseases, Parasitic14.6%
27Pregnancy Complications, Parasitic14.6%
28Liver Abscess, Amebic14.6%
29Parasitemia14.4%
30Cestode Infections14.3%
31Helminthiasis, Animal14.3%
32Nematode infections14.3%
33Trematode Infections14.3%
34Toxoplasmosis, Congenital12.7%
35Fascioliasis12.1%
36Larva Migrans12%
37Opportunistic Infections11.5%
38Echinococcosis, Hepatic11.1%
39Toxocariasis11%
40Dirofilariasis10.9%
41Diphyllobothriasis10.3%
42Echinococcosis10.3%
43Hymenolepiasis10.3%
44Mite Infestations10.3%
45Myiasis10.3%
46Opisthorchiasis10.3%
47Schistosomiasis10.3%
48Tick Infestations10.3%
49Secernentea Infections10.3%
50Onchocerciasis10.3%
51Strongyle Infections, Equine9.3%
52Neurocysticercosis8.7%
53Toxoplasmosis, Cerebral8.6%
54Cysticercosis8.5%
55Hypodermyiasis8.5%
56Schistosomiasis japonica8.5%
57Schistosomiasis mansoni8.5%
58Sparganosis8.5%
59Ascaridida Infections8.5%
60Oxyurida Infections8.5%
61Ascariasis7.6%
62Filariasis7.6%
63Gnathostomiasis7.6%
64Hookworm Infections7.6%
65Oxyuriasis7.6%
66Strongyloidiasis7.6%
67Trichinellosis7.6%
68Trichostrongyloidiasis7.6%
69Loiasis7.1%
70Enterobiasis7.1%
71Superinfection7%
72Lice Infestations6.7%
73Malaria, Cerebral5%
74AIDS-Related Opportunistic Infections4.6%
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.