Quinine
(AKYHKWQPZHDOBW-DSXUQNDKSA-N)
Structure
- SMILES
- OS(=O)(=O)O.C=C[C@H]1CN2CC[C@H]1C[C@H]2[C@@H](c1ccnc2c1cc(OC)cc2)O
- Molecular Formula:
- C20H26N2O6S
- Molecular Weight:
- 422.495
- Log P:
- 3.5391
- Hydrogen Bond Acceptor:
- 8
- Hydrogen Bond Donor:
- 3
- TPSA:
- 128.57
- CAS Number(s):
- 549-56-4; 804-63-7; 6119-70-6
Synonym(s)
1.
Quinine
2.
Biquinate
3.
Legatrim
4.
Myoquin
5.
Quinamm
6.
Quinbisan
7.
Quinbisul
8.
Quindan
9.
Quinimax
10.
Quinine Bisulfate
11.
Quinine Hydrochloride
12.
Quinine Lafran
13.
Quinine Sulfate
14.
Quinine Sulphate
15.
Quinine-Odan
16.
Quinoctal
17.
Quinson
18.
Quinsul
19.
Strema
20.
Surquina
21.
Bisulfate, Quinine
22.
Hydrochloride, Quinine
23.
Sulfate, Quinine
24.
Sulphate, Quinine
External Link(s)
| MeSH | D011803 |
| PubChem Compound | 11949689 |
| CHEMBL | CHEMBL1201100 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Thrombocytopenia | FAERS: 61 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 2 | Acute kidney injury | FAERS: 32 | US FAERS | |
| 3 | Blindness | FAERS: 25 | US FAERS | |
| 4 | Deafness | FAERS: 18 | US FAERS | |
| 5 | Thrombocytopenic purpura | FAERS: 18 | US FAERS | |
| 6 | Cerebrovascular accident | FAERS: 8 | US FAERS | |
| 7 | Retinal toxicity | FAERS: 6 | US FAERS | |
| 8 | Unevaluable event | FAERS: 6 | US FAERS | |
| 9 | Overdose | FAERS: 5 | US FAERS | |
| 10 | Vomiting | FAERS: 5 | US FAERS | |
| 11 | Optic Atrophy | FAERS: 4 | US FAERS | |
| 12 | Headache | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 13 | Nausea | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 14 | Pain | FAERS: 3 | US FAERS | |
| 15 | Tinnitus | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 16 | Anxiety | FAERS: 2 | US FAERS | |
| 17 | Asthenia | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 18 | Blood sodium decreased | FAERS: 2 | US FAERS | |
| 19 | Chest Pain | FAERS: 2 | US FAERS | |
| 20 | Dizziness | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 21 | Drug toxicity | FAERS: 2 | US FAERS | |
| 22 | Dysgeusia | FAERS: 2 | US FAERS | |
| 23 | Medication Error | FAERS: 2 | US FAERS | |
| 24 | Neutropenia | FAERS: 2 | US FAERS | |
| 25 | Pancytopenia | FAERS: 2 | US FAERS | |
| 26 | Petechiae | FAERS: 2 | US FAERS | |
| 27 | Photophobia | FAERS: 2 | US FAERS | |
| 28 | Pruritus | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 29 | Retinal Artery Occlusion | FAERS: 2 | US FAERS | |
| 30 | Retinal Degeneration | FAERS: 2 | US FAERS | |
| 31 | Retinitis Pigmentosa | FAERS: 2 | US FAERS | |
| 32 | Swelling | FAERS: 2 | US FAERS | |
| 33 | Syncope | FAERS: 2 | US FAERS | |
| 34 | Toxicity to various agents | FAERS: 2 | US FAERS | |
| 35 | Visual Impairment | FAERS: 2 | US FAERS | |
| 36 | Activities of daily living impaired | FAERS: 1 | US FAERS | |
| 37 | Alanine Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 38 | Aneurysm | FAERS: 1 | US FAERS | |
| 39 | Angina Pectoris | FAERS: 1 | US FAERS | |
| 40 | Anuria | FAERS: 1 | US FAERS | |
| 41 | Arteriosclerosis | FAERS: 1 | US FAERS | |
| 42 | Aspartate Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 43 | Atrial Fibrillation | FAERS: 1 | US FAERS | |
| 44 | Back Pain | FAERS: 1 | US FAERS | |
| 45 | Bilirubin conjugated increased | FAERS: 1 | US FAERS | |
| 46 | Blood albumin decreased | FAERS: 1 | US FAERS | |
| 47 | Blood alkaline phosphatase increased | FAERS: 1 | US FAERS | |
| 48 | Blood potassium decreased | FAERS: 1 | US FAERS | |
| 49 | Catheter site infection | FAERS: 1 | US FAERS | |
| 50 | Chest discomfort | FAERS: 1 | US FAERS | |
| 51 | Complication associated with device | FAERS: 1 | US FAERS | |
| 52 | Dehydration | FAERS: 1 | US FAERS | |
| 53 | Diabetes Mellitus | FAERS: 1 | US FAERS | |
| 54 | Drug ineffective | FAERS: 1 | US FAERS | |
| 55 | Drug ineffective for unapproved indication | FAERS: 1 | US FAERS | |
| 56 | Economic problem | FAERS: 1 | US FAERS | |
| 57 | Electrolyte imbalance | FAERS: 1 | US FAERS | |
| 58 | Emotional disorder | FAERS: 1 | US FAERS | |
| 59 | Feeling of body temperature change | FAERS: 1 | US FAERS | |
| 60 | Gangrene | FAERS: 1 | US FAERS | |
| 61 | Gastritis | FAERS: 1 | US FAERS | |
| 62 | Gout | FAERS: 1 | US FAERS | |
| 63 | Hypersensitivity | FAERS: 1 | US FAERS | |
| 64 | Hyperventilation | FAERS: 1 | US FAERS | |
| 65 | Hypotension | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 66 | Impaired driving ability | FAERS: 1 | US FAERS | |
| 67 | Impaired work ability | FAERS: 1 | US FAERS | |
| 68 | Incorrect dose administered | FAERS: 1 | US FAERS | |
| 69 | Intercepted drug dispensing error | FAERS: 1 | US FAERS | |
| 70 | Limb discomfort | FAERS: 1 | US FAERS | |
| 71 | Limb injury | FAERS: 1 | US FAERS | |
| 72 | Lyme Disease | FAERS: 1 | US FAERS | |
| 73 | Macular dystrophy congenital | FAERS: 1 | US FAERS | |
| 74 | Malaise | FAERS: 1 | US FAERS | |
| 75 | Metastatic Neoplasm | FAERS: 1 | US FAERS | |
| 76 | Mydriasis | FAERS: 1 | US FAERS | |
| 77 | Pseudocyst | FAERS: 1 | US FAERS | |
| 78 | Retching | FAERS: 1 | US FAERS | |
| 79 | Retinal Vascular Disorder | FAERS: 1 | US FAERS | |
| 80 | Retinal depigmentation | FAERS: 1 | US FAERS | |
| 81 | Retinal pigment epitheliopathy | FAERS: 1 | US FAERS | |
| 82 | Supraventricular tachycardia | FAERS: 1 | US FAERS | |
| 83 | Tremor | FAERS: 1 | US FAERS | |
| 84 | Urticaria | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 85 | Abdominal discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 86 | Amnesia | Canada Vigilance: 1 | Canada Vigilance | |
| 87 | Anaphylactoid Reaction | Canada Vigilance: 1 | Canada Vigilance | |
| 88 | Cerebellar Hypoplasia | Canada Vigilance: 1 | Canada Vigilance | |
| 89 | Chills | Canada Vigilance: 1 | Canada Vigilance | |
| 90 | Disorientation | Canada Vigilance: 1 | Canada Vigilance | |
| 91 | Erythema | Canada Vigilance: 1 | Canada Vigilance | |
| 92 | Optic Neuritis | Canada Vigilance: 1 | Canada Vigilance | |
| 93 | Rash erythematous | Canada Vigilance: 3 | Canada Vigilance | |
| 94 | Stevens-Johnson Syndrome | Canada Vigilance: 1 | Canada Vigilance | |
| 95 | Stupor | Canada Vigilance: 1 | Canada Vigilance |
Powered by :
Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120235
Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.